Physical Stress, Not Biotic Interactions, Preclude an Invasive Grass from Establishing in Forb-Dominated Salt Marshes

Biological invasions have become the focus of considerable concern and ecological research, yet the relative importance of abiotic and biotic factors in controlling the invasibility of habitats to exotic species is not well understood. Spartina species are highly invasive plants in coastal wetlands; however, studies on the factors that control the success or failure of Spartina invasions across multiple habitat types are rare and inconclusive.We examined the roles of physical stress and plant interactions in mediating the establishment of the smooth cordgrass, Spartina alterniflora, in a variety of coastal habitats in northern China. Field transplant experiments showed that cordgrass can invade mudflats and low estuarine marshes with low salinity and frequent flooding, but cannot survive in salt marshes and high estuarine marshes with hypersaline soils and infrequent flooding. The dominant native plant Suaeda salsa had neither competitive nor facilitative effects on cordgrass. A common garden experiment revealed that cordgrass performed significantly better when flooded every other day than when flooded weekly. These results suggest that physical stress rather than plant interactions limits cordgrass invasions in northern China.We conclude that Spartina invasions are likely to be constrained to tidal flats and low estuarine marshes in the Yellow River Delta. Due to harsh physical conditions, salt marshes and high estuarine marshes are unlikely to be invaded. These findings have implications for understanding Spartina invasions in northern China and on other coasts with similar biotic and abiotic environments

Pathogenic mechanisms and clinical implications of congenital neutropenia syndromes

Purpose of reviewThe purpose of this review is to summarize pathogenic mechanisms and clinical implications of the most illustrative genetic entities of congenital neutropenia syndromes.Recent findingsCongenital neutropenia comprise monogenetic entities with or without additional immunologic and extrahaematopoietic syndromatic features. Continuous careful explorations of known entities such as ELANE, GFI1, HAX1, G6PC3 deficiency and XLN help to define principles controlling differentiation and function of neutrophil granulocytes. Furthermore, the identification of novel genetic defects associated with congenital neutropenia, such as VPS45 deficiency, broadens our understanding of neutrophil biology. Pathogenic mechanisms imply protein and vesicle mistrafficking, endoplasmic reticulum stress, the unfolded protein response, destabilization of the mitochondrial membrane potential, disturbed energy metabolism, dysglycosylation and deregulated actin polymerization.SummaryAdvanced genetic and biochemical techniques have helped to expand our knowledge of congenital neutropenia syndromes. Known and novel genetic entities shed light on fundamental biological processes important for the homeostatis and functioning not only of the neutrophil granulocyte but as well of the entire haematopoietic system. Furthermore, treatment decisions become more tailored and might pave the road towards personalized molecular medicine

Ritual plants of Muslim graveyards in northern Israel

This article surveys the botanical composition of 40 Muslim graveyards in northern Israel, accompanied by an ethnobotanical study of the folkloristic traditions of the use of these plants in cemeteries. Three groups of plants were found to be repeated systematically and were also recognized for their ritual importance: aromatics herbs (especially Salvia fruticosa and Rosmarinus officinalis), white flowered plants (mainly Narcissus tazetta, Urginea maritima, Iris spp. and Pancratium spp.) and Cupressus sempervirens as the leading cemetery tree. As endemic use we can indicate the essential role of S. fruticosa as the main plant used in all human rites of passage symbolizing the human life cycle. The rosemary is of European origin while the use of basil is of Indian influence. The use of white flowers as cemeteries plants reflects an old European influence and almost the same species are used or their congeners. Most of the trees and shrubs that are planted in Muslim cemeteries in Israel have the same use in ancient as well in modern European cultures. In conclusion, our findings on the occurrence of plants in graveyards reflect the geographic situation of Israel as a crossroads in the cultural arena between Asia and Europe. Most of the traditions are common to the whole Middle East showing high relatedness to the classical world as well as to the present-day Europe

Mitochondrial ATP synthase: architecture, function and pathology

Human mitochondrial (mt) ATP synthase, or complex V consists of two functional domains: F1, situated in the mitochondrial matrix, and Fo, located in the inner mitochondrial membrane. Complex V uses the energy created by the proton electrochemical gradient to phosphorylate ADP to ATP. This review covers the architecture, function and assembly of complex V. The role of complex V di-and oligomerization and its relation with mitochondrial morphology is discussed. Finally, pathology related to complex V deficiency and current therapeutic strategies are highlighted. Despite the huge progress in this research field over the past decades, questions remain to be answered regarding the structure of subunits, the function of the rotary nanomotor at a molecular level, and the human complex V assembly process. The elucidation of more nuclear genetic defects will guide physio(patho)logical studies, paving the way for future therapeutic interventions

Search for Gamma-Ray and Neutrino Coincidences Using HAWC and ANTARES Data

In the quest for high-energy neutrino sources, the Astrophysical Multimessenger Observatory Network (AMON) has implemented a new search by combining data from the High Altitude Water Cherenkov (HAWC) observatory and the Astronomy with a Neutrino Telescope and Abyss environmental RESearch (ANTARES) neutrino telescope. Using the same analysis strategy as in a previous detector combination of HAWC and IceCube data, we perform a search for coincidences in HAWC and ANTARES events that are below the threshold for sending public alerts in each individual detector. Data were collected between July 2015 and February 2020 with a livetime of 4.39 years. Over this time period, 3 coincident events with an estimated false-alarm rate of $< 1$ coincidence per year were found. This number is consistent with background expectations.Comment: 12 pages, 5 figures, 3 table

“Against the Dog Only a Dog”. Talking Canines Civilizing Cynicism in Cervantes’ “coloquio de los perros” (With Tentative Remarks on the Discourse and Method of Animal Studies)

Deriving its designation from the Greek word for ‘dog’, cynicism is likely the only philosophical ‘interest group’ with a diachronically dependable affinity for various animals—particularly those of the canine kind. While dogs have met with differing value judgments, chiefly along a perceived human–animal divide, it is specifically discourses with cynical affinities that render problematic this transitional field. The Cervantine “coloquio de los perros” has received scholarly attention for its (caninely) picaresque themes, its “cynomorphic” (Ziolkowski) narratological technique, its socio-historically informative accounts relating to Early Modern Europe and the Iberian peninsula, including its ‘zoopoetically’ (Derrida) relevant portrayal of dogs (see e.g., Alves, Beusterien, Martín); nor did the dialog’s mention of cynical snarling go unnoticed. The essay at hand commences with a chapter on questions of method pertaining to ‘animal narration’: with recourse to Montaigne, Descartes, and Derrida, this first part serves to situate the ensuing close readings with respect to the field of Animal Studies. The analysis of the Cervantine texts synergizes thematic and narratological aspects at the discourse historical level; it commences with a brief synopsis of the respective novellas in part 2; Section 3, Section 4 and Section 5 supply a description of the rhetorical modes of crafting plausibility in the framework narrative (“The Deceitful Marriage”), of pertinent (Scriptural) intertexts for the “Colloquy”. Parts 6–7 demonstrate that the choice of canine interlocutors as narrating agencies—and specifically in their capacity as dogs—is discursively motivated: no other animal than this animal, and precisely as animal, would here serve the discursive purpose that is concurrently present with the literal plane; for this dialogic novella partakes of a (predominantly Stoicizing) tradition attempting to resocialize the Cynics, which commences already with the appearance of the Ancient arch-Cynic ‘Diogenes’ on the scene. At the discursive level, a diachronic contextualization evinces that the Cervantine text takes up and outperforms those rhetorical techniques of reintegration by melding Christian, Platonic, Stoicizing elements with such as are reminiscent of Diogenical ones. Reallocating Blumenberg’s reading of a notorious Goethean dictum, this essay submits the formula ‘against the Dog only a dog’ as a concise précis of the Cervantine method at the discursive level, attained to via a decidedly pluralized rhetorical sermocination featuring, at a literal level, specifically canine narrators in a dialogic setting