phi puzzle in heavy-ion collisions at 2 AGeV: how many K-from phi decays?

The preliminary experimental data on $\phi$ production in the reaction Ni(1.93 AGeV) + Ni point to a puzzling high $\phi$ yield which can not be reproduced with present transport codes. We survey the experimental situation and present prospects for dedicated measurements of the $\phi$ multiplicities with the $K^+ K^-$ and $e^+ e^-$ channels at HADES and FOPI.Comment: talk at Strange Quarks in Matter 2001, Frankfurt Sep. 24 - 29, 200

Констpукції з прийменником з як адвербіальні синтаксеми

Статья касается проблемы семантического арсенала конструкции из предлогом з как адвербиальной синтаксемы. Характеризуется возможность употребления этой конструкции як адвербиальной синтaксемы. Приводятся примеры функционирования этой конструкции как каузальной, темпоральной и целевой синтаксемы.Стаття стосується проблеми семантичного арсеналу конструкції з прийменником з як адвербіальної синтаксеми. Характеризується можливість вживання цієї конструкції як адвербіальної синтаксеми. Наводяться приклади функціонування цієї конструкції як темпоральної, причинової і цільової синтаксеми.The article concerns the problem of semantic arsenal of construction with as adverbial syntactic units. Is ability of usage in the sentence as adverbial syntactic units is characterized. The examples of the functioning of this construction as temporal causal purpose syntaxems are given

Correlations and Characterization of Emitting Sources

Dynamical and thermal characterizations of excited nuclear systems produced during the collisions between two heavy ions at intermediate incident energies are presented by means of a review of experimental and theoretical work performed in the last two decades. Intensity interferometry, applied to both charged particles (light particles and intermediate mass fragments) and to uncharged radiation (gamma rays and neutrons) has provided relevant information about the space-time properties of nuclear reactions. The volume, lifetime, density and relative chronology of particle emission from decaying nuclear sources has been extensively explored and has provided valuable information about the dynamics of heavy-ion collisions. Similar correlation techniques applied to coincidences between light particles and complex fragments are also presented as a tool to determine the internal excitation energy of excited primary fragments as it appears in secondary-decay phenomena.Comment: To appear on Euorpean Physics Journal A as part of the Topical Volume "Dynamics and Thermodynamics with Nuclear Degrees of Freedom

Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus

Background: Synthesis of the Staphylococcus aureus peptidoglycan pentaglycine interpeptide bridge is catalyzed by the nonribosomal peptidyl transferases FemX, FemA and FemB. Inactivation of the femAB operon reduces the interpeptide to a monoglycine, leading to a poorly crosslinked peptidoglycan. femAB mutants show a reduced growth rate and are hypersusceptible to virtually all antibiotics, including methicillin, making FemAB a potential target to restore β-lactam susceptibility in methicillin-resistant S. aureus (MRSA). Cis-complementation with wild type femAB only restores synthesis of the pentaglycine interpeptide and methicillin resistance, but the growth rate remains low. This study characterizes the adaptations that ensured survival of the cells after femAB inactivation. Results: In addition to slow growth, the cis-complemented femAB mutant showed temperature sensitivity and a higher methicillin resistance than the wild type. Transcriptional profiling paired with reporter metabolite analysis revealed multiple changes in the global transcriptome. A number of transporters for sugars, glycerol, and glycine betaine, some of which could serve as osmoprotectants, were upregulated. Striking differences were found in the transcription of several genes involved in nitrogen metabolism and the arginine-deiminase pathway, an alternative for ATP production. In addition, microarray data indicated enhanced expression of virulence factors that correlated with premature expression of the global regulators sae, sarA, and agr. Conclusion: Survival under conditions preventing normal cell wall formation triggered complex adaptations that incurred a fitness cost, showing the remarkable flexibility of S. aureus to circumvent cell wall damage. Potential FemAB inhibitors would have to be used in combination with other antibiotics to prevent selection of resistant survivors

Differential directed flow in Au+Au collisions

We present experimental data on directed flow in semi-central Au+Au collisions at incident energies from 90 to 400 A MeV. For the first time for this energy domain, the data are presented in a transverse momentum differential way. We study the first order Fourier coefficient v1 for different particle species and establish a gradual change of its patterns as a function of incident energy and for different regions in rapidity.Comment: 5 pages, Latex, 5 eps figures, accepted for publication in Phys. Rev. C (Rapid Communications). Data files available at http://www-linux.gsi.de/~andronic/fopi/v1.htm

Lambda-proton correlations in relativistic heavy ion collisions

The prospect of using lambda-proton correlations to extract source sizes in relativistic heavy ion collisions is investigated. It is found that the strong interaction induces a large peak in the correlation function that provides more sensitive source size measurements than two-proton correlations under some circumstances. The prospect of using lambda-proton correlations to measure the time lag between lambda and proton emissions is also studied.Comment: 4 pages, 3 figure, revtex style. Two short paragraphs are added at referees' recommendations. Phys. Rev. Lett. in pres

Flow angle from intermediate mass fragment measurements

Directed sideward flow of light charged particles and intermediate mass fragments was measured in different symmetric reactions at bombarding energies from 90 to 800 AMeV. The flow parameter is found to increase with the charge of the detected fragment up to Z = 3-4 and then turns into saturation for heavier fragments. Guided by simple simulations of an anisotropic expanding thermal source, we show that the value at saturation can provide a good estimate of the flow angle, $\Theta_{flow}$, in the participant region. It is found that $\Theta_{flow}$ depends strongly on the impact parameter. The excitation function of $\Theta_{flow}$ reveals striking deviations from the ideal hydrodynamical scaling. The data exhibit a steep rise of \Theta_{\flow} to a maximum at around 250-400 AMeV, followed by a moderate decrease as the bombarding energy increases further.Comment: 28 pages Revtex, 6 figures (ps files), to appear in Nucl.Phys.

Novel low resistivity glass: MRPC detectors for ultra high rate applications

Abstract Multigap Resistive Plate Chambers (MRPCs) are often used as time-of-flight (TOF) detectors for high-energy physics and nuclear experiments thanks to their excellent time accuracy. For the Compressed Baryonic Matter (CBM) TOF system, MRPCs are required to work at particle fluxes on the order of 1-10 kHz/ c m 2 for the outer region and 10-25 kHz/ c m 2 for the central region. Better time resolution will allow particle identification with TOF techniques to be performed at higher momenta. From our previous studies, a time resolution of 25 ps has been obtained with a 20-gap MRPC of 140 μ m gap size with enhanced rate capbability. By using a new type of commercially available thin low-resistivity glass, further improvement MRPC rate capability is possible. In order to study the rate capability of the 10-gap MRPC built with this new low-resistivity glass, we have performed tests using the continuous electron beam at ELBE. This 10-gap MRPC, with 160 μ m gaps, reaches 97% efficiency at 19.2 kV and a time resolution of 36 ps at particle fluxes near 2 kHz/ c m 2 . At a flux of 100 kHz/ c m 2 , the efficiency is still above 95% and a time resolution of 50 ps is obtained, which would fulfil the requirement of CBM TOF system

Evaluation of rate law approximations in bottom-up kinetic models of metabolism.

BackgroundThe mechanistic description of enzyme kinetics in a dynamic model of metabolism requires specifying the numerical values of a large number of kinetic parameters. The parameterization challenge is often addressed through the use of simplifying approximations to form reaction rate laws with reduced numbers of parameters. Whether such simplified models can reproduce dynamic characteristics of the full system is an important question.ResultsIn this work, we compared the local transient response properties of dynamic models constructed using rate laws with varying levels of approximation. These approximate rate laws were: 1) a Michaelis-Menten rate law with measured enzyme parameters, 2) a Michaelis-Menten rate law with approximated parameters, using the convenience kinetics convention, 3) a thermodynamic rate law resulting from a metabolite saturation assumption, and 4) a pure chemical reaction mass action rate law that removes the role of the enzyme from the reaction kinetics. We utilized in vivo data for the human red blood cell to compare the effect of rate law choices against the backdrop of physiological flux and concentration differences. We found that the Michaelis-Menten rate law with measured enzyme parameters yields an excellent approximation of the full system dynamics, while other assumptions cause greater discrepancies in system dynamic behavior. However, iteratively replacing mechanistic rate laws with approximations resulted in a model that retains a high correlation with the true model behavior. Investigating this consistency, we determined that the order of magnitude differences among fluxes and concentrations in the network were greatly influential on the network dynamics. We further identified reaction features such as thermodynamic reversibility, high substrate concentration, and lack of allosteric regulation, which make certain reactions more suitable for rate law approximations.ConclusionsOverall, our work generally supports the use of approximate rate laws when building large scale kinetic models, due to the key role that physiologically meaningful flux and concentration ranges play in determining network dynamics. However, we also showed that detailed mechanistic models show a clear benefit in prediction accuracy when data is available. The work here should help to provide guidance to future kinetic modeling efforts on the choice of rate law and parameterization approaches