845 research outputs found

    Construction of UEQ+ scales for voice quality: measuring user experience quality of voice interaction

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    The UEQ+ is a modular framework for the construction of UX questionnaires. The researcher can pick those scales that fit his or her research question from a list of 16 available UX scales. Currently, no UEQ+ scales are available to allow measuring the quality of voice interactions. Given that this type of interaction is increasingly essential for the usage of digital products, this is a severe limitation of the possible products and usage scenarios that can be evaluated using the UEQ+. We describe in this paper the construction of three specific scales to measure the UX of voice interactions. Besides, we discuss how these new scales can be combined with existing UEQ+ scales in evaluation projects

    Structure and localization of mRNA encoding a pigment dispersing hormone (PDH) in the eyestalk of the crayfish Orconectes limosus

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    AbstractThe pigment-dispersing hormone (PDH) is produced in the eyestalks of Crustacea where it induces light-adapting movements of pigment in the compound eye and regulates the pigment dispersion in the chromatophores. To study this hormone at the mRNA level, we cloned and sequenced cDNA encoding PDH in the crayfish Orconectes limosus. The structure of the PDH preprohormone consists of a signal peptide, a PDH precursor-related peptide (PPRP) and the highly conserved PDH peptide at the carboxy-terminal end. In situ hybridization in combination with immunocytochemistry revealed four cell clusters expressing PDH in the optic ganglia of the eyestalk. Three clusters stained both with the PDH cRNA probe and the PDH antiserum, however, the perikarya in the lamina ganglionaris (LG) only stained with the PDH antiserum, suggesting the presence of a PDH-like peptide in the LG

    Ammonium Pertechnetate in Mixtures of Trifluoromethanesulfonic Acid and Trifluoromethanesulfonic Anhydride

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    Ammonium pertechnetate reacts in mixtures of trifluoromethanesulfonic anhydride and trifluoromethanesulfonic acid under final formation of ammonium pentakis(trifluoromethanesulfonato)oxidotechnetate(V), (NH4_{4})2_{2} [TcO(OTf) 5_{5}]. The reaction proceeds only at exact concentrations and under the exclusion of air and moisture via pertechnetyl trifluoromethanesulfonate, [TcO3_{3}(OTf)], and intermediate TcVI^{VI} species. 99^{99}Tc nuclear magnetic resonance (NMR) has been used to study the TcVII^{VII} compound and electron paramagnetic resonance (EPR), 99^{99}Tc NMR and X-ray absorption near-edge structure (XANES) experiments indicate the presence of the reduced technetium species. In moist air, (NH4_{4})2[TcO(OTf)5] slowly hydrolyses under formation of the tetrameric oxidotechnetate(V) (NH4_{4})4_{4} [{TcO(TcO4_{4})4_{4}}4_{4}] ⋅10 H2_{2}O. Single-crystal X-ray crystallography was used to determine the solid-state structures. Additionally, UV/Vis absorption and IR spectra as well as quantum chemical calculations confirm the identity of the species

    Metal induced folding: Synthesis and conformational analysis of the lanthanide complexes of two 44-membered hydrazone macrocycles

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    Six new lanthanide complexes of two 44-membered macrocycles have been prepared and characterised in solution. An analysis of the conformations of the free macrocycles and their lanthanide complexes both in solution (2D NMR) and in solid state (X-ray crystallography) demonstrate that the complexation induces changes in folding of the macrocycles

    Strangeness Suppression in Proton-Proton Collisions

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    We analyse strangeness production in proton-proton (pp) collisions at SPS and RHIC energies, using the recently advanced NeXus approach. After having verified that the model reproduces well the existing data, we interpret the results: strangeness is suppressed in proton-proton collisions at SPS energy as compared to electron-positron (e+e-) annihilation due to the limited masses of the strings produced in the reaction, whereas high energy pp and e+e- collisions agree quantitatively . Thus strangeness suppression at SPS energies is a consequence of the limited phase-space available in string fragmentation.Comment: 7 Figures, 4 Page

    On the genetic involvement of apoptosis-related genes in Crohn's disease as revealed by an extended association screen using 245 markers: no evidence for new predisposing factors

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    Crohn's disease (CD) presents as an inflammatory barrier disease with characteristic destructive processes in the intestinal wall. Although the pathomechanisms of CD are still not exactly understood, there is evidence that, in addition to e.g. bacterial colonisation, genetic predisposition contributes to the development of CD. In order to search for predisposing genetic factors we scrutinised 245 microsatellite markers in a population-based linkage mapping study. These microsatellites cover gene loci the encoded protein of which take part in the regulation of apoptosis and (innate) immune processes. Respective loci contribute to the activation/suppression of apoptosis, are involved in signal transduction and cell cycle regulators or they belong to the tumor necrosis factor superfamily, caspase related genes or the BCL2 family. Furthermore, several cytokines as well as chemokines were included. The approach is based on three steps: analyzing pooled DNAs of patients and controls, verification of significantly differing microsatellite markers by genotyping individual DNA samples and, finally, additional reinvestigation of the respective gene in the region covered by the associated microsatellite by analysing single-nucleotide polymorphisms (SNPs). Using this step-wise process we were unable to demonstrate evidence for genetic predisposition of the chosen apoptosis- and immunity-related genes with respect to susceptibility for CD

    Leading-order determination of the gluon polarisation from semi-inclusive deep inelastic scattering data

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    Using a novel analysis technique, the gluon polarisation in the nucleon is re-evaluated using the longitudinal double-spin asymmetry measured in the cross section of semi-inclusive single-hadron muoproduction with photon virtuality Q2>1 (GeV/c)2Q^2>1~({\rm GeV}/c)^2. The data were obtained by the COMPASS experiment at CERN using a 160 GeV/cc polarised muon beam impinging on a polarised 6^6LiD target. By analysing the full range in hadron transverse momentum pTp_{\rm T}, the different pTp_{\rm T}-dependences of the underlying processes are separated using a neural-network approach. In the absence of pQCD calculations at next-to-leading order in the selected kinematic domain, the gluon polarisation Δg/g\Delta g/g is evaluated at leading order in pQCD at a hard scale of μ2=Q2=3(GeV/c)2\mu^2= \langle Q^2 \rangle = 3 ({\rm GeV}/c)^2. It is determined in three intervals of the nucleon momentum fraction carried by gluons, xgx_{\rm g}, covering the range 0.04 ⁣< ⁣xg ⁣< ⁣0.280.04 \!<\! x_{ \rm g}\! <\! 0.28~ and does not exhibit a significant dependence on xgx_{\rm g}. The average over the three intervals, Δg/g=0.113±0.038(stat.)±0.036(syst.)\langle \Delta g/g \rangle = 0.113 \pm 0.038_{\rm (stat.)}\pm 0.036_{\rm (syst.)} at xg0.10\langle x_{\rm g} \rangle \approx 0.10, suggests that the gluon polarisation is positive in the measured xgx_{\rm g} range.Comment: 14 pages, 6 figure

    Resource Heterogeneity Moderates the Biodiversity-Function Relationship in Real World Ecosystems

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    Numerous recent studies have tested the effects of plant, pollinator, and predator diversity on primary productivity, pollination, and consumption, respectively. Many have shown a positive relationship, particularly in controlled experiments, but variability in results has emphasized the context-dependency of these relationships. Complementary resource use may lead to a positive relationship between diversity and these processes, but only when a diverse array of niches is available to be partitioned among species. Therefore, the slope of the diversity-function relationship may change across differing levels of heterogeneity, but empirical evaluations of this pattern are lacking. Here we examine three important functions/properties in different real world (i.e., nonexperimental) ecosystems: plant biomass in German grasslands, parasitism rates across five habitat types in coastal Ecuador, and coffee pollination in agroforestry systems in Indonesia. We use general linear and structural equation modeling to demonstrate that the effect of diversity on these processes is context dependent, such that the slope of this relationship increases in environments where limiting resources (soil nutrients, host insects, and coffee flowers, respectively) are spatially heterogeneous. These real world patterns, combined with previous experiments, suggest that biodiversity may have its greatest impact on the functioning of diverse, naturally heterogeneous ecosystems

    Measurement of the charged-pion polarisability

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    The COMPASS collaboration at CERN has investigated pion Compton scattering, πγπγ\pi^-\gamma\rightarrow \pi^-\gamma, at centre-of-mass energy below 3.5 pion masses. The process is embedded in the reaction πNiπγ  Ni\pi^-\mathrm{Ni}\rightarrow\pi^-\gamma\;\mathrm{Ni}, which is initiated by 190\,GeV pions impinging on a nickel target. The exchange of quasi-real photons is selected by isolating the sharp Coulomb peak observed at smallest momentum transfers, Q2<0.0015Q^2<0.0015\,(GeV/cc)2^2. From a sample of 63\,000 events the pion electric polarisability is determined to be $\alpha_\pi\ =\ (\,2.0\ \pm\ 0.6_{\mbox{\scriptsize stat}}\ \pm\ 0.7_{\mbox{\scriptsize syst}}\,) \times 10^{-4}\,\mbox{fm}^3undertheassumption under the assumption \alpha_\pi=-\beta_\pi$, which relates the electric and magnetic dipole polarisabilities. It is the most precise measurement of this fundamental low-energy parameter of strong interaction, that has been addressed since long by various methods with conflicting outcomes. While this result is in tension with previous dedicated measurements, it is found in agreement with the expectation from chiral perturbation theory. An additional measurement replacing pions by muons, for which the cross-section behavior is unambigiously known, was performed for an independent estimate of the systematic uncertainty.Comment: Published version: 9 pages, 3 figures, 1 tabl
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