104 research outputs found

    Self-processes in interdependent relationships: Partner affirmation and the Michelangelo Phenomenon

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    This essay reviews theory and research regarding the "Michelangelo phenomenon," which describes the manner in which close partners shape one another's dispositions, values, and behavioral tendencies. Individuals are more likely to exhibit movement toward their ideal selves to the degree that their partners exhibit affirming perception and behavior, exhibiting confidence in the self 's capacity and enacting behaviors that elicit key features of the self 's ideal. In turn, movement towards the ideal self yields enhanced personal well-being and couple well-being. We review empirical evidence regarding this phenomenon and discuss self and partner variables that contribute to the process. © John Benjamins Publishing Company

    Challenges and Opportunities for Spark Plasma Sintering: A Key Technology for a New Generation of Materials

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    This is an open access article distributed under the terms of the Creative Commons Attribution License.-- et al.Peer reviewe

    Discontinuation of RAAS Inhibition in Children with Advanced CKD

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    Background and objectives Although renin-angiotensin-aldosterone system inhibition (RAASi) is a cornerstone in the treatment of children with CKD, it is sometimes discontinued when kidney function declines. We studied the reasons of RAASi discontinuation and associations between RAASi discontinuation and important risk markers of CKD progression and on eGFR decline in the Cardiovascular Comorbidity in Children with CKD study. Design, setting, participants,& measurements In this study, 69 children with CKD(67% male, mean age 13.7 years, mean eGFR 27 ml/min per 1.73m(2)) who discontinued RAASi during prospective follow-up were included. Initial change in BP, albuminuria, and potassium after discontinuation were assessed (median time 6 months). Rate of eGFR decline (eGFR slope) during a median of 1.9 years before and 1.2 years after discontinuation were estimated using linear mixed effects modeling. Results Physician-reported reasons for RAASi discontinuation were increase in serum creatinine, hyperkalemia, and symptomatic hypotension. After discontinuation of RAASi, BP and albuminuria increased, whereas potassium decreased. eGFR declined more rapidly after discontinuation of RAASi (23.9 ml/min per 1.73m2 per year; 95% confidence interval, 25.1 to 22.6) compared with the slope during RAASi treatment (21.5 ml/min per 1.73 m(2) per year; 95% confidence interval, 22.4 to 20.6; P=0.005). In contrast, no change in eGFR slope was observed in a matched control cohort of patients in whom RAASi was continued. Conclusions Discontinuation of RAASi in children with CKD is associated with an acceleration of kidney function decline, even in advanced CKD

    Hindered E4 decay of the 12+ yrast trap in 52Fe

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    AbstractThe Îł decay of the 12+ yrast trap in 52Fe has been measured for the first time. The two E4 Îł-branches to the 8+ states are hindered with respect to other B(E4) reduced transition probabilities measured in the f7/2 shell. The interpretation of the data is given in the full pf shell model framework, comparing the results obtained with different residual interactions. It is shown that measurements of hexadecapole transition probabilities constitute a powerful tool in discriminating the correct configuration of the involved wavefunctions

    Hindered E4 decay of the 12+ yrast trap in 52Fe

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    Abstract The Îł decay of the 12 + yrast trap in 52Fe has been measured for the first time. The two E4 Îł-branches to the 8 + states are hindered with respect to other B ( E 4 ) reduced transition probabilities measured in the f 7 / 2 shell. The interpretation of the data is given in the full pf shell model framework, comparing the results obtained with different residual interactions. It is shown that measurements of hexadecapole transition probabilities constitute a powerful tool in discriminating the correct configuration of the involved wavefunctions

    Fine structure of the Gamow-Teller resonance revealed in the decay of Ho-150 2(-) isomer

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    The Îł rays following the 72s 150Ho 2- Gamow-Teller ÎČ decay have been investigated with the CLUSTER CUBE setup, an array of six EUROBALL CLUSTER Ge detectors in close cubic geometry, providing a Îł ray detection sensitivity of 2×10-5 per ÎČ-parent decay for Îł-ray energies up to 5 MeV. The fine structure of the Gamow-Teller resonance at 4.4-MeV excitation in 150Dy has been studied. The resolved levels are compared with Shell Model predictions

    Progress Report on Target Development

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    The present document is the D08 deliverable report of work package 1 (Target Development) from the MEGAPIE TEST project of the 5th European Framework Program. Deliverable D08 is the progress report on the activities performed within WP 1. The due date of this deliverable was the 5th month after the start of the EU project. This coincided with a technical status meeting of the MEGAPIE Initiative, that was held in March 2002 in Bologna (Italy). The content of the present document reflects the status of the MEGAPIE target development at that stage. It gives an overview of the Target Design, the related Design Support activities and the progress of the work done for the safety assessment and licensing of the target

    5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity

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    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
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