174 research outputs found
Palatal development of preterm and low birthweight infants compared to term infants – What do we know? Part 3: Discussion and Conclusion
- Author
- A Erenberg
- A Erenberg
- A Erenberg
- A Hohoff
- A Hohoff
- AJ Nowak
- AM Procter
- Ariane Hohoff
- AS Von Gonten
- B Behrstock
- B Klemke
- BC Leighton
- BL Shapiro
- BS Saunders
- DE Kopra
- DE Kopra
- DW Smith
- EK Biskinis
- Erik Harms
- FA Berry
- FM Moylan
- G Ginoza
- G Pettett
- GM Angelos
- GW Ginoza
- H Krous
- Heike Rabe
- I Kjær
- J Hall
- J Stocks
- JB Boice
- JF Bosma
- JH Sillman
- JR Jasmin
- JW Hanson
- KA Rosenzweig
- KL Watterberg
- KL Watterberg
- KM Morris
- KM Morris
- L Clinch
- L Paulsson
- L Rubenstein
- LM Solomon
- LP Gray
- LP Gray
- LV Macey-Dare
- M Marin-Padilla
- M Mellander
- M Neumann
- MJ Miller
- MM Warwick-Brown
- P Neal
- PJ Carrillo
- PM Duke
- R Gorlin
- R Metz
- RA Molteni
- RA Molteni
- RC Tsang
- RC Wetzel
- RJ Baxter
- RM Viscardi
- S Fadavi
- S Fadavi
- S Fadavi
- S Howell
- SE Kent
- SP Ash
- TNK Raju
- Ulrike Ehmer
- VB Knott
- W Kim Seow
- WH Ginther
- WK Seow
- WK Seow
- WK Seow
- Y Funakoshi
- Publication venue
- BioMed Central
- Publication date
- 01/11/2005
- Field of study
BACKGROUND: It has been hypothesized that prematurity and adjunctive neonatal care is 'a priori' a risk for disturbances of palatal and orofacial development which increases the need for later orthodontic or orthognathic treatment. As results on late consequences of prematurity are consistently contradictory, the necessity exists for a fundamental analysis of existing methodologies, confounding factors, and outcomes of studies on palatal development in preterm and low birthweight infants. METHOD: A search of the literature was conducted based on Cochrane search strategies including sources in English, German, and French. Original data were recalculated from studies which primarily dealt with both preterm and term infants. The extracted data, especially those from non-English paper sources, were provided unfiltered in tables for comparison (Parts 1 and 2). RESULTS: Morphology assessment of the infant palate is subject to non-standardized visual and metrical measurements. Most methodologies are inadequate for measuring a three-dimensional shape. Several confounding factors were identified as causes contributing to disturbances of palatal and orofacial development. CONCLUSION: Taking into account the abovementioned shortcomings, the following conclusions may be drawn for practitioners and prospective investigators of clinical studies. 1) The lack of uniformity in the anatomical nomenclature of the infant's palate underlines the need for a uniform definition. 2) Metrically, non-intubated preterm infants do not exhibit different palatal width or height compared to matched term infants up to the corrected age of three months. Beyond that age, no data on the subject are currently available. 3) Oral intubation does not invariably alter palatal morphology of preterm and low birthweight infants. 4) The findings on palatal grooving, height, and asymmetry as a consequence of orotracheal intubation up to the age of 11 years are inconsistent. 5) Metrically, the palates of orally intubated infants remain narrower posteriorly, beginning at the second deciduous molar, until the age of 11 years. Beyond that age, no data on the subject are currently available. 6) There is a definite need for further, especially metrical, longitudinal and controlled trials on palatal morphology of preterm and low birthweight infants with reliable measuring techniques. 7) None of the raised confounding factors for developmental disturbances may be excluded until evident results are presented. Thus, early orthodontic and logopedic control of formerly premature infants is recommended up to the late mixed dentition stage
Palatal development of preterm and low birthweight infants compared to term infants – What do we know? Part 2: The palate of the preterm/low birthweight infant
- Author
- A Björk
- A Erenberg
- A Erenberg
- A Erenberg
- A Hohoff
- A Hohoff
- AG Huddart
- AJ Nowak
- AM Elliman
- AM Procter
- AR Spitzer
- Ariane Hohoff
- AS Von Gonten
- B Behrstock
- B Klemke
- BC Leighton
- BS Saunders
- BS Saunders
- C Updike
- CL Donley
- D Raval
- DE Kopra
- DE Kopra
- DJ Marsden
- E Robke
- EK Biskinis
- Erik Harms
- G Collins
- G Ginoza
- G Pettett
- GM Angelos
- GM Chan
- GW Ginoza
- H Bakwin
- H Krous
- H Ott
- Heike Rabe
- I Dittrich
- JB Boice
- JD Baum
- JH Sillman
- JP Deffez
- JR Jasmin
- KL Watterberg
- KL Watterberg
- KM Morris
- KM Morris
- L Clinch
- L Lebret
- LV Macey-Dare
- M Neumann
- MF Ashley-Montagu
- MM Warwick-Brown
- MW Woolridge
- N Rutter
- P Neal
- PG Sullivan
- PG Sullivan
- PH Cartlidge
- PJ Carrillo
- PM Duke
- PY Lai
- R Arens
- R Van Erum
- RA Molteni
- RA Molteni
- S Adeni
- S Adeni
- S Fadavi
- S Fadavi
- S Fadavi
- S Fadavi
- S Howell
- S Oelschlägl
- SE Kent
- SP Ash
- Ulrike Ehmer
- VB Knott
- W Kim Seow
- WK Seow
- Y Burns
- Publication venue
- BioMed Central
- Publication date
- 01/01/2005
- Field of study
BACKGROUND: Well-designed clinical studies on the palatal development in preterm and low birthweight infants are desirable because the literature is characterized by contradictory results. It could be shown that knowledge about 'normal' palatal development is still weak as well (Part 1). The objective of this review is therefore to contribute a fundamental analysis of methodologies, confounding factors, and outcomes of studies on palatal development in preterm and low birthweight infants. METHODS: An electronic literature search as well as hand searches were performed based on Cochrane search strategies including sources of more than a century in English, German, and French. Original data were recalculated from studies which primarily dealt with both preterm and term infants. The extracted data, especially those from non-English paper sources, were provided unfiltered for comparison. RESULTS: Seventy-eight out of 155 included articles were analyzed for palatal morphology of preterm infants. Intubation, feeding tubes, feeding mode, tube characteristics, restriction of oral functions, kind of diet, cranial form and birthweight were seen as causes contributing to altered palatal morphology. Changes associated with intubation concern length, depth, width, asymmetry, crossbite, and contour of the palate. The phenomenon 'grooving' has also been described as a complication associated with oral intubation. However, this phenomenon suffers from lack of a clear-cut definition. Head flattening, pressure from the oral tube, pathologic or impaired tongue function, and broadening of the alveolar ridges adjacent to the tube have been raised as causes of 'grooving'. Metrically, the palates of intubated preterm infants remain narrower, which has been examined up to the age of the late mixed dentition. CONCLUSION: There is no evidence that would justify the exclusion of any of the raised causes contributing to palatal alteration. Thus, early orthodontic and logopedic control of formerly orally intubated preterm infants is recommended, as opposed to non-intubated infants. From the orthodontic point of view, nasal intubation should be favored. The role that palatal protection plates and pressure-dispersing pads for the head have in palatal development remains unclear
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
- A Antolick
- A Arthur
- A Aslam
- Abaci F
- Abdullakutty J
- Abhaichand R
- Abib E Jr
- Aboufakher R
- Abrantes J
- Abreu M
- Abulencia K
- Acampora D
- Acampora M
- Accini Mendoza Jl
- Aceto L
- Acevedo B
- Acevedo L
- Acheatel R
- Actis Mv
- Adams M
- Adjic Nc
- Affaki Gs
- Agarwal Dk
- Aggarwal Rk
- Agosta Gf
- Aguilar M
- Aguilar M
- Ahire N
- Ahmad I
- Ahmed Sh
- Ahn Y
- Aish B
- Aiub F
- Aiub J
- Ajax K
- Ajioka M
- Akai Y
- Akatova E
- Akrap B
- Al Joundi T
- Al-Khalili F
- Albisu J
- Alcalde Jm
- Alcide P
- Alfonso T
- Allen J
- Alllison Dc
- Almaliky T
- Amerena J
- Andersen K
- Andor M
- Angelova I
- Angiolillo D
- Anita S
- Anker Sd
- Antalik L
- Antonicelli R
- Aparicio Cv
- Apel T
- Apostolovic S
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- Ardissino D
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- Argiolas G
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- Asim Oktay Ao
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- Klein P
- Klemsdal To
- Kleve R
- Klugherz B
- Knight J
- Knutsson A
- Koba M
- Kobalava Z
- Kodem Dr
- Koeitti P
- Koenig W
- Kojima E
- Kok M
- Koldas N
- Koleckar P
- Kolikova V
- Kolleroy C
- Kolokathis F
- Komati S
- Komura Y
- Kondagunta V
- Konradi A
- Kooiman E
- Kopaczewski J
- Kopczyńska M
- Korban E
- Koren M
- Kormann A
- Korte M
- Korth-Wiemann B
- Kose V
- Kosmacheva E
- Kostakou P
- Kostis J
- Kotek L
- Kouz Sm
- Kovacic D
- Kovacs A
- Kozak M
- Kozlova S
- Krapivsky A
- Kreckova M
- Kreutter F
- Krupciakova B
- Krupicka J
- Kuenzler J
- Kulibaba E
- Kulkarni L
- Kullal P
- Kultursay H
- Kumar Ks
- Kumbla M
- Kuntzsch A
- Kuo Jy
- Kuramochi T
- Kuruma T
- Kusnick B
- Kuzin A
- Kyo E
- L Levinson
- L Lim
- L Link
- L Liu
- Laane E
- Labovitz R
- Lachance P
- Lai Wt
- Lail J
- Lainscak M
- Lake J
- Lal S
- Lamance J
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- Lambert J
- Lameira A
- Lamontagne C
- Landers B
- Landolfi A
- Landzberg J
- Lang C
- Langdon J
- Laniec M
- Lappo M
- Lardinois R
- Laszlo Z
- Latheef K
- Laube S
- Lauzon C
- Lavoie W
- Lazov P
- Ledger G
- Lee Hn
- Lee J
- Lee Jh
- Lee K
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- Lee Sc
- Lee Sh
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- Leggewie S
- Lehman Kf
- Lehman R
- Lehmann D
- Leimbach W
- Lekakis J
- Lembo G
- Lenderink T
- Lennard M
- Lenner E
- Lennerova J
- Leon S
- Lepage S
- Lepor N
- Lepp H
- Lester F
- Levin P
- Levine D
- Lewis D
- Li W
- Li X
- Li Y
- Li Y
- Li Y
- Li Yh
- Li Z
- Libby P
- Liberato Nl
- Libov I
- Lierse T
- Ligueros M
- Lillo J
- Lima F
- Limaye Ap
- Lin T
- Lindholm Cj
- Lindner C
- Liniado G
- Lino E
- Lipchenko A
- Liu B
- Liu B
- Liu Hm
- Liu P
- Liu S
- Liu Y
- Liviu C
- Lock E
- Lohkare M
- Lok Dja
- Long C
- Longaker R
- Lopes R
- Lopez P
- Lorch G
- Lorenc Z
- Lorenzatti A
- Lousberg A
- Lozhkina N
- Lu Z
- Luciardi H
- Lucksinger G
- Luecke-Uzar M
- Luedemann J
- Lukac J
- Lundqvist M
- Lupkovics G
- Luquez H
- Luz Serrano H
- Lv Y
- Lynd S
- Lysek R
- Lönnberg I
- M Malek
- M Mallagray
- M Mandati
- M Mandviwala
- M Marsters
- M Mays
- M Mcdonald
- M Medvegy
- M Meinrich
- M Mikus
- M Milanova
- M Moustafa
- Ma C
- Ma G
- Maboyi S
- Macdonald J
- Macfadyen Jg
- Machova V
- Madder R
- Maehara G
- Maffei L
- Magness K
- Maheshwari A
- Maheux K
- Maia L
- Majercak I
- Majul C
- Makedonska Jj
- Makhe B
- Makotoko E
- Malchikova S
- Maletz L
- Malhotra S
- Malhotra V
- Malik J
- Mancikova I
- Mandic L
- Manenti E
- Manfreda S
- Manga P
- Mani Ck
- Mani H
- Manne S
- Manning B
- Mannucci E
- Manolis A
- Manolis Aj
- Manov E
- Mantas I
- Manuel J
- Manukov D
- Manukov I
- Manyari D
- Manzur F
- Marcela Wenetz Lm
- Marchelletta N
- Marchi Al
- Marcinkeviciene J
- Marcun R
- Marengo Garcia De Carvalho L
- Marinaro S
- Marino P
- Mariottoni B
- Maron B
- Marschke T
- Marshall L
- Martin E
- Martin L
- Martinez E
- Martinez J
- Maruzzo S
- Marziali A
- Masarikova L
- Massaccesi R
- Mathew A
- Matyasek I
- Mauersberger K
- Maus O
- Mavromatis K
- Maximov D
- Mayer T
- Maynard R
- Mays B
- Mazutavicius R
- Mbulaiteye A
- Mcalister R
- Mccoy C
- Mccrary D Jr
- Mccullough-O'Brien H
- Mcgill J
- Mcgrew F
- Mcintosh C
- Mckenzie A
- Mckenzie C
- Mckibbin A
- Mclaurin B
- Mclellan Ba
- Mcmahon G
- Mcneil D
- Mcneill R
- Mcpherson C
- Medina F
- Megalou A
- Mehrle A
- Mehta A
- Mehta S
- Meijlis P
- Meissner A
- Mejia I
- Melbie K
- Mellberg L
- Melliza T
- Mendoza N
- Mendoza Y
- Mercuro G
- Merkely B
- Messina T
- Mestdagh I
- Meyer R
- Michalaros Y
- Michalska A
- Michaud N
- Michel K
- Mickel C
- Micko K
- Mihaly N
- Mikdadi G
- Mikusova T
- Milicic D
- Militaru C
- Miliuniene R
- Milkas A
- Miller A
- Miller C
- Miller G
- Miller R
- Miller W
- Minescu B
- Minocha G
- Mitchell J
- Mittal A
- Miyamoto T
- Moats Djr
- Modi R
- Mody F
- Moehring B
- Moen S
- Moffat J
- Mohan K
- Molina Di
- Molk B
- Molter D
- Monroe T
- Montana O
- Montenegro E
- Montenegro P
- Montero H
- Montgomery R
- Monti L
- Moodh J
- Mooe T
- Mookherjee D
- Moon K
- Moraes J Jr
- Moran J
- Moreira L
- Morell Y
- Moriarty P
- Morii I
- Morinaga Y
- Morisawa T
- Morozov E
- Morrison J
- Morton D
- Mos L
- Moshayedi P
- Mosley J
- Motiejuniene R
- Muehlhaus J
- Mueller S
- Muenter Kc
- Muenzel T
- Mulder R
- Munoz N
- Munoz R
- Munshi K
- Muntaner J
- Mureddu V
- Murphy G
- Murray A
- Mustafa J
- Musumeci Mb
- Muñoz W
- Myslyaeva L
- Nadar V
- Nagai Y
- Nagele-Luse I
- Nagy Ac
- Naidu R
- Naka T
- Nakamura S
- Nakamura Y
- Nakayoshi K
- Nalley J
- Nanas J
- Nandy P
- Naumann R
- Navarrete S
- Navy S
- Nebel J
- Neil L
- Nema D
- Neumann J
- Neutel Jm
- Niblack P
- Nicely V
- Nicolai M
- Nicolau J
- Nijmeh G
- Nikas A
- Nikoletta P
- Nikolic L
- Nikyar A
- Nilsen V
- Ning M
- Nishibe A
- Nixon S
- Nociar J
- Noori E
- Norin V
- Norkiene S
- Norkute-Macijauske U
- Norman L
- Noto G
- Nour K
- Novo S
- Nuding S
- Nugent A
- Nugteren Skz
- Ocman B
- Odegard A
- Ogawa H
- Ogawa M
- Okada Y
- Okawa M
- Okeefe D
- Olenchock B
- Olmedo M
- Olofsson M
- Olsen S
- Olsson Gh
- Olympios Cd
- Ondrasik J
- Onuchina E
- Oomman A
- Ord M
- Ortiz-Carrasquillo R
- Ossino N
- Otasevic P
- Otava M
- Otis R
- Otterstad Je
- Ouimet F
- Overhoff U
- Ozcan It
- O’Neil G
- P Pais
- P Peters
- P Piatti
- P Poliacik
- P Povolny
- P Purnell
- Pacora Ff
- Paez H
- Paganini M
- Page A
- Pagett K
- Pagnan M
- Pai R
- Pai V
- Palaniswami N
- Palatkina T
- Palchick B
- Pales J
- Paliwal Y
- Palka J Jr
- Palubova L
- Pande R
- Pandey S
- Paniagua A
- Pannell R
- Panov A
- Pansheriya A
- Panzarino C
- Papke B
- Parekh N
- Parente A
- Parepa I
- Parfait V
- Park B
- Park C
- Parmon E
- Partridge J
- Patel B
- Patel J
- Patel M
- Patel R
- Patel R
- Patel S
- Patino Jm
- Patole T
- Patsilinakos S
- Paulweber B
- Pavlickova L
- Paysor C
- Paz S
- Peck C
- Pella D
- Pena A
- Pencz I
- Peng L
- Penzes J
- Pereira S
- Perez Manghi F
- Perez A
- Perez M
- Perkins H
- Perkins L
- Perlstein T
- Perotti M
- Perperis A
- Perry B
- Pesce F
- Petelina T
- Peter Y
- Peterka M
- Petrauskiene B
- Petrescu L
- Petrillo C
- Petrov D
- Petrova I
- Petrusheva T
- Pettersen Ki
- Peukert Am
- Phillippi C
- Phillips A
- Phillips A
- Piacente R
- Pieretti Hb
- Pinheiro L
- Pintado M
- Pirenne B
- Pish R
- Piskorz D
- Pitt W
- Planinc I
- Ploechl A
- Plotz M
- Podoleanu C
- Pogson A
- Pokorna B
- Polato C
- Poling T
- Pomposini D
- Ponce T
- Poock J
- Pool T
- Poor F
- Pop Cf
- Popa V
- Popescu E
- Popovic Z
- Potts J
- Poudrier R
- Poulimenos L
- Pradhan A
- Pramatarova I
- Praveen M
- Prenner A
- Price D
- Price R
- Prior J
- Priori S
- Pritchard C
- Procter K
- Pupic L
- Purighalla R
- Pye M
- Qing L
- Quddusi K
- Quinones J
- Quinton D
- R Rauch
- R Recoaro
- R Reyes
- R Roettges
- R Rummel
- Racca V
- Radde I
- Radeljic V
- Radhakrishnan V
- Radin M
- Radoi M
- Radojcsics B
- Radvan M
- Raev D
- Ragghianti B
- Raghu C
- Rajan B A
- Rajasekhar D
- Rajput B
- Raju Ss
- Rama B
- Ramdas S
- Ramos G
- Ramos M
- Rancane G
- Randvee L
- Ranjith N
- Rao M
- Rao Mb
- Rao Nm
- Rassi S
- Rathnavel S
- Rathore A
- Rathore Srs
- Ratnik E
- Rau T
- Rawat S
- Raynes K
- Reber Am
- Reddy J
- Reddy Nc
- Redfearn H
- Rees Dh
- Reeves M
- Regner S
- Reichenbach D
- Reilly K
- Reimand M
- Reimer D
- Reinmets S
- Reis G
- Reis H
- Ren L
- Renaud K
- Renda G
- Repin A
- Resende I
- Resnick H
- Rewbury J
- Reznakova S
- Reznik I
- Rhudy Jm
- Richardson M
- Richert L
- Rickova Z
- Ridker Pm
- Riethof M
- Righini V
- Rinke A
- Risberg K
- Risenfors M
- Riser J
- Rivis L
- Robbins K
- Roberts-Thomson P
- Robinson S
- Rodero M
- Rodriguez Araya E
- Rodriguez A
- Rodriguez D
- Rodriguez J
- Rodriguez Lm
- Rodriguez Sm
- Roel A
- Romano A
- Romanski A
- Roos J
- Roper L
- Ross B
- Rossi Prf
- Rost N
- Roszkowska P
- Rotreklova M
- Roy A
- Roy C
- Roy M
- Rozeman P
- Ruder D
- Rudys A
- Ruffini L
- Rugo H
- Runev N
- Runquist L
- Rupka D
- Ruschel K
- Ryding A
- Rönndahl M
- Rønnevik P
- Rønnevik Td
- S Sarah
- S Sasaki
- S Sathe
- S Seki
- S Sharma
- S Shayani
- S Shetty
- S Shustov
- S Srivastava
- S Stadelmeier
- S Stoltz
- S Strand
- S Strugatsky
- S Such
- Sabo L
- Sack G
- Sahin M
- Sahin T
- Saini R
- Saint-Jacques H
- Saka B
- Sakamoto Y
- Sakurada M
- Salfity M
- Salinger M
- Salko T
- Sall N
- Saloustros I
- Salvador L
- Sam K
- Samal A
- Samer H
- Samkova D
- Sanchez Vallejo G
- Sanchez A
- Sanchez D
- Sang X
- Santiago J Jr
- Santosh Mj
- Sanuri M
- Saporito W
- Saraiva Jf
- Saravia Ma
- Sarbu I
- Sarcone M
- Sarjanovich R
- Sarma R
- Sarnighausen He
- Sarszegi Z
- Sattar N
- Saunders K
- Savard D
- Savignano C
- Saylor R
- Sazonova E
- Scaro G
- Scheffel M
- Scheibner T
- Schermaul Kh
- Schiavi Lb
- Schifferdecker B
- Schindler A
- Schindler A
- Schindler E
- Schlundt C
- Schmidt E
- Schmidt K
- Schnabel A
- Schneider P
- Schneider R
- Schnitzler R
- Schoen N
- Schorn K
- Schrager B
- Schroeder T
- Schulenburg D
- Schultz C
- Schulz M
- Schulze J
- Schulze U
- Schumacher M
- Schwartz A
- Schwerin G
- Schwerin M
- Schäfer B
- Sciborski R
- Scott J
- Scott R
- Seals A
- Senni M
- Sergienko T
- Seroqui M
- Servaes V
- Sesto I
- Seung Kb
- Shah A
- Shah Av
- Shah J
- Shaikh P
- Shanahan T
- Shaposhnik I
- Shapovalova Y
- Sharma K
- Sharma T
- Sharp A
- Shatsky K
- Shaw P
- Shealy N
- Sheets L
- Shelley J
- Shepard P
- Shetty P
- Shimokawa H
- Shimomura H
- Shinozaki T
- Shvarts Y
- Sidhu G
- Siemann M
- Sigurdadottir E
- Sigurdsson A
- Silva R
- Silver K
- Simay A
- Sime I
- Simon J
- Simon M
- Simons N
- Simpson H
- Singerling M
- Singh K
- Singh N
- Singh V
- Singhal A
- Sinnaeve P
- Siostrzonek P
- Sirakova-Taseva A
- Sirnes Pa
- Sizemore Bc
- Skalicka H
- Skatrud L
- Skjelvan G
- Skopets I
- Skubova K
- Skuladottir F
- Skuratova M
- Slanina M
- Slapikas R
- Slayton C
- Slechticka A
- Slimak V
- Sloane G
- Smallwood B
- Smeele F
- Smik R
- Smith B
- Smith G
- Smith J
- Smith J
- Smith M
- Smith M
- Smith P
- Smith T
- Smith W
- Smith W
- Smolenskaya O
- Soca Y
- Socoteanu E
- Socoteanu G
- Sofley C
- Sohi Gs
- Solares A
- Soler J
- Solovev O
- Song M
- Sopko K
- Soro E
- Sorodoc L
- Sosa-Padilla M
- Sotolongo R
- Sotomayor A
- Soucy D
- Spiridon M
- Sprinkle B
- Squire I
- Srdos V
- Srinath Vs
- St Amour E
- Stahl A
- Stahl Hd
- Stanciulescu G
- Starzec M
- Stefanescu M
- Steinhoff J
- Stelly L
- Steringer-Mascherbauer R
- Stern M
- Sternthal P
- Stinson J
- Stitova M
- Stockhausen G
- Stockhausen J
- Stoddard M
- Stoessel J
- Stofkova D
- Stokuca-Korac N
- Stolze K
- Stone B
- Stonkute K
- Storey R
- Stover T
- Strain J
- Stratmann M
- Strazdiene D
- Strbova J
- Stroes E
- Strohner-Kaestenbauer H
- Stys T
- Sugimoto N
- Suleman A
- Sullivan P
- Sun Z
- Sundelin R
- Suorra I
- Sutalo K
- Suzuki A
- Swart Hp
- Szacinski G
- Szakal I
- Szatmarine V
- Szocs A
- Szpajer M
- Szymanowski N
- T Tase
- T Tekten
- T Thuren
- T Tjaden
- Taguchi S
- Tahk S
- Tahon S
- Takahashi J
- Takase S
- Talliard C
- Tamburrini P
- Tamesby G
- Tamez W
- Tan M
- Tan R
- Tanabe K
- Tanaka A
- Tanaseanu C
- Tandon N
- Tani S
- Taqueti V
- Taran A
- Taverner P
- Tawfik R
- Teenan M
- Telekes P
- Teltser M
- Ten Holt W
- Terry K
- Terry Ps
- Tesak M
- Teschner Ab
- Teske A
- Tessmar C
- Thakkar B
- Thekkoott D
- Theunissen E
- Thiessen S
- Thomas D
- Thomas Dm
- Thomas H
- Thompson E
- Thompson J
- Thornton A
- Tijuneliene E
- Tinnirello V
- Tisheva-Gospodinova S
- Tobias C
- Todorova A
- Tomassi A
- Tomioka J
- Toom M
- Topper J
- Torgersruud M
- Torstensson I
- Torun A
- Toth P
- Townend J
- Tran A
- Treasure C
- Trenkamp P
- Trevelyan J
- Trevino M
- Trofimov V
- Troquay Rpt
- Tsai Mc
- Tsao Hm
- Tsioufis K
- Tsorbatzoglou K
- Tsou L
- Tsuboi H
- Tsuji M
- Tsujita K
- Tsujiyama S
- Tudoran M
- Tuholske C
- Turner F
- Tusek S
- Tzekova M
- Tzong L
- Ucar N
- Uecker C
- Ueng Kc
- Umesu A
- Unterkircher B
- Urbonas G
- Uresin S
- Urgeova L
- Urina M
- Urina-Triana M
- Uy W
- V Vahula
- V Vijan
- V Vora
- Vahtel M
- Vaid B
- Valenzuela M
- Valle M
- Vallejo Ma
- Vallone L
- Van Der Wal M
- Van Der Zwaan C
- Van Genechten G
- Van Kempen Ww
- Van Maarseveen M
- Van Stein I
- Vanagiene S
- Vance A
- Vandam J
- Vanhecke T
- Vanness WC Iii
- Vardas P
- Vargas R
- Varigos J
- Vasiliev M
- Vaz S
- Vazquez Tanus J
- Veerina K
- Vega J
- Vegsundvåg J
- Veit S
- Velusamy K
- Vento A
- Venturini C
- Vertes G
- Vervoort G
- Vesely J
- Vesely P
- Vesga B
- Vettus R
- Veze I
- Vezikova N
- Vezina M
- Vibert J
- Vicente C
- Vico Ml
- Vida-Simiti L
- Vieira N
- Viergever Ep
- Viezelis M
- Vijay N
- Villani Gq
- Vinanska D
- Vincelli G
- Vins P
- Viola Hg
- Visseren Flj
- Vissers C
- Vitovec M
- Vodnansky P
- Voelker F
- Voeller H
- Vogel M
- Vogt E
- Vold D
- Volpe M
- Voors C
- Vora K
- Vorster M
- Voyzey Ej
- Vozzhaev A
- Vranckx P
- Vrolix M
- Vuriya Ak
- W Wu
- Wade Rd
- Wadell C
- Wakeling J
- Waksman R
- Walker K
- Walker K
- Wallace K
- Walter I
- Walter J
- Walther I
- Walukiewicz P
- Wanderley Ff
- Wang Cp
- Wang Hc
- Wang J
- Wang Y
- Wang Yl
- Warren M
- Washam M
- Watson B
- Webel R
- Weber Hg
- Wei J
- Wei N
- Weimer J
- Weisnagel Sj
- Wells T
- West M
- Westberg Jc
- Whitaker J
- White A
- White A
- White C
- White J
- Wichterich K
- Wiebusch A
- Wilhoit G
- Wilkins M
- Wilkinson S
- William M
- Willingham K
- Willmerdinger M
- Willner C
- Wilson S
- Wilson V
- Winkelmann B
- Winkler J
- Wise J
- Wistuba T
- Woehrle J
- Woelcke J
- Wohnlich T
- Wolf S
- Woodall S
- Woods A
- Woyczak D
- Wrage P
- Wright J
- Wu J
- Wu J
- Wujkowski M
- Wyss F
- Xavier Jp
- Xu H
- Xu Zj
- Yakovova S
- Yakushin S
- Yamada T
- Yamaguchi E
- Yamamoto H
- Yamamoto T
- Yamane M
- Yan J
- Yanase T
- Yanev T
- Yang Cc
- Yang K
- Yang P
- Yao Z
- Yaoqing H
- Yarows S
- Yasuoka S
- Yasutake M
- Yigit Z
- Yilmaz Mb
- Yim Kh
- Yim S
- Yokoyama M
- Yong H
- Yoshida M
- Yoshimoto E
- Yossen M
- Young A
- Younis L
- Youssef G
- Yuan Z
- Yunoki C
- Yupanqui H
- Z Zhai
- Z Zilahi
- Zadionchenko V
- Zadra R
- Zagozen P
- Zaidman C
- Zalazar L
- Zaman A
- Zangroniz P
- Zarate J
- Zareczky P
- Zarifis I
- Zdrenghea D
- Zebrack J
- Zena N
- Zhang J
- Zhang W
- Zhang Y
- Zhao R
- Zhou H
- Zidova M
- Zielinski M
- Zieve F
- Zineldine A.
- Zirlik A
- Zucchetti C
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
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- Zhang Y
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- Zhang Z
- Zhao H
- Zhao T
- Zhao Y
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- Zhao Z
- Zhemchugov A
- Zheng J
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
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- Zhu CG
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- Zhukov K
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at
= 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
Effect of adjuvant trastuzumab treatment in conventional clinical setting: an observational retrospective multicenter Italian study
- Author
- A Hasan
- A. Balsari
- A. Bologna
- A. Fabi
- C Palmieri
- C Rosales
- D Slamon
- D. Giuffrida
- DH Jones
- DJ Slamon
- DJ Slamon
- DM Reese
- DR Cox
- E Tagliabue
- E. Ferri
- E. Tagliabue
- E. Tarenzi
- E. Valle
- EC Dijkers
- EH Romond
- EJ Bowles
- F. Bianchi
- F. Riccardi
- G. Mustacchi
- G. Tabaro
- H Joensuu
- H Kennecke
- HA Azim
- I Smith
- KL Blackwell
- L Gianni
- M Procter
- M Spielmann
- M. Campiglio
- M. Sasso
- MJ Piccart-Gebhart
- N Niikura
- O Metzger-Filho
- P Carter
- P. Casalini
- R. Aiello
- R. Bufalino
- S. Ménard
- SR Johnston
- SV Sharma
- TM Suter
- V. Adamo
- V. Scotti
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The neighbourhood physical environment and active travel in older adults: a systematic review and meta-analysis
- Author
- A Barnett
- A Barnett
- A Etman
- A Martin
- A Nathan
- A Nathan
- A Nathan
- AA Laverty
- AC King
- AC King
- AM Chudyk
- Andrea Nathan
- Anthony Barnett
- B Chaix
- B Giles-Corti
- BE Saelens
- BJ Boruff
- BJ Kelly
- CF Mendes de Leon
- D Ding
- D King
- D Moher
- D Ogilvie
- D Rainham
- DA Dillman
- David W. Barnett
- DD Dunlop
- Department of Infrastructure and transport
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Leslie
- E Procter-Gray
- Ester Cerin
- GR McCormack
- HB Menz
- J Boone-Heinonen
- J Cauwenberg Van
- J Cauwenberg Van
- J Cauwenberg Van
- J Cauwenberg Van
- J Cohen
- J Davey
- J Garrard
- J Jarrett
- J Kerr
- J Kerr
- J Pelclová
- J Sallis
- J Woodcock
- JA Carlson
- Jelle van Cauwenberg
- JF Sallis
- JL Maisel
- JPT Higgins
- JR Willis
- K Berkemeyer
- K Gebel
- K Witten
- KE Lamb
- KK Davison
- KL Cain
- L Foley
- L Frank
- LB Christiansen
- LL Barnes
- LT Tsai
- M Bland
- M Johnson
- M Moniruzzaman
- M Moniruzzaman
- M Moran
- M Tainio
- M Takemoto
- MA Alfonzo
- MG Davis
- MR Franco
- MS Nyunt
- MW Corseuil
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- NL Bracy
- NW Burton
- P Kelly
- PA Jackson
- PK Patterson
- R Barnes
- R Ewing
- R Rosenthal
- R Shigematsu
- S Foster
- S Inoue
- S O’Hern
- SC Webber
- SK Keadle
- SL Handy
- T Sugiyama
- TL Kolbe-Alexander
- V Holle Van
- V Holle Van
- V Holle Van
- World Health Organisation
- World Health Organization
- X Cao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index
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- Abecasis GR
- Absher D
- Albrecht E
- Alizadeh B
- Amin N
- Amouyel P
- Arking DE
- Ascari G
- Asselbergs FW
- Assimes TL
- Atalay M
- Attwood AP
- Aubert V
- Balmforth AJ
- Barcella M
- Barroso I
- Basart H
- Beckmann JS
- Beilby J
- Bell JT
- Benyamin B
- Berg J
- Bergmann S
- Berndt SI
- Blackwood D
- Bochud M
- Bochud P-Y
- Boehm BO
- Boehnke M
- Boerwinkle E
- Boerwinkle E
- Boezen HM
- Bonnycastle LL
- Boomsma DI
- Borecki IB
- Borecki IB
- Bragg-Gresham JL
- Brambilla P
- Bruinenberg M
- Bruinenberg M
- Bültmann U
- Cadby G
- Campbell H
- Campbell H
- Caulfield MJ
- Cavanagh J
- Chakravarti A
- Chambers JC
- Chanock SJ
- Chasman DI
- Chines PS
- Collins FS
- Connell J
- Connell JM
- Connor M
- Cookson W
- Croteau-Chonka DC
- Cunningham-Burley S
- Cupples LA
- Cusi D
- Cusi D
- Da Smith G
- Dauvilliers Y
- Day FR
- De Bakker P
- De Boer R
- De Faire U
- De Vegt F
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- Dominiczak A
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- Eklund N
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- Erdmann J
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- Esko T
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- Evans DM
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- Fall T
- Farrall Martin
- Feitosa MF
- Ferrario MM
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- Fiorito G
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- Ford I
- Fox CS
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- Gustafsson S
- Gyllensten U
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- Publication venue
- Publication date
- 01/01/2014
- Field of study
Marja-Liisa Lokki työryhmien Generation Scotland Consortium, LifeLines Cohort Study ja GIANT Consortium jäsenPeer reviewe
Search for dark photons in rare Z boson decays with the ATLAS detector
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- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
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- Abusleme Hoffman AC
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- Ai X
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- Akbiyik M
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- Akiyama D
- Akolkar NN
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- Alberghi GL
- Albert J
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- Alderweireldt S
- Aleksa M
- Aleksandrov IN
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- Alfonsi A
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- Ali B
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- ATLAS Collaboration
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- Yildiz H Duran
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- Yuan R
- Yue L
- Zaazoua M
- Zabinski B
- Zaid E
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- Zamora Saa JA
- Zang J
- Zanzi D
- Zaplatilek O
- Zeitnitz C
- Zeng H
- Zeng JC
- Zenger DT
- Zenin O
- Zenz S
- Zerradi S
- Zerwas D
- Zhai M
- Zhang B
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- Zhang J
- Zhang J
- Zhang K
- Zhang L
- Zhang P
- Zhang R
- Zhang S
- Zhang T
- Zhang X
- Zhang X
- Zhang Y
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao H
- Zhao P
- Zhao T
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng K
- Zheng X
- Zheng Z
- Zhong D
- Zhou B
- Zhou H
- Zhou N
- Zhou Y
- Zhu CG
- Zhu J
- Zhu Y
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas TG
- Zormpa O
- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2023
- Field of study
A search for events with a dark photon produced in association with a dark Higgs boson via rare decays of the standard model
Z
boson is presented, using
139
fb
−
1
of
√
s
=
13
TeV
proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider. The dark boson decays into a pair of dark photons, and at least two of the three dark photons must each decay into a pair of electrons or muons, resulting in at least two same-flavor opposite-charge lepton pairs in the final state. The data are found to be consistent with the background prediction, and upper limits are set on the dark photon’s coupling to the dark Higgs boson times the kinetic mixing between the standard model photon and the dark photon,
α
D
ϵ
2
, in the dark photon mass range of [5, 40] GeV except for the
Υ
mass window [8.8, 11.1] GeV. This search explores new parameter space not previously excluded by other experiments
Combined measurement of the Higgs boson mass from the H → γγ and H → ZZ∗ → 4ℓ decay channels with the ATLAS detector using √s = 7, 8, and 13 TeV pp collision data
- Author
- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
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- Zhemchugov A
- Zheng J
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- Zimine NI
- Zinsser J
- Ziolkowski M
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- Zorbas TG
- Zormpa O
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- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2023
- Field of study
A measurement of the mass of the Higgs boson combining the
H
→
Z
Z
∗
→
4
ℓ
and
H
→
γ
γ
decay channels is presented. The result is based on
140
fb
−
1
of proton-proton collision data collected by the ATLAS detector during LHC run 2 at a center-of-mass energy of 13 TeV combined with the run 1 ATLAS mass measurement, performed at center-of-mass energies of 7 and 8 TeV, yielding a Higgs boson mass of
125.11
±
0.09
(
stat
)
±
0.06
(
syst
)
=
125.11
±
0.11
GeV
. This corresponds to a 0.09% precision achieved on this fundamental parameter of the Standard Model of particle physics
- …