42 research outputs found
Reduction of Dental Decay in Rampant Caries Individuals Following Short-Term Kanamycin Treatment
A week of kanamycin gel treatment before and after the placement of dental restorations, compared to a placebo gel treatment, significantly reduced the levels of cultivable bacteria, S mutans and S sanguis, in the plaque samples collected immediately after the completion of the gel treatments, and was associated with a 46% reduction in new carious surfaces in the 14- to 37-month period following the gel treatment.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68298/2/10.1177_00220345770560031101.pd
Production of Massless Fermions during Inflation
We compute the one loop self energy, in a locally de Sitter background, for a
massless fermion which is Yukawa-coupled to a massless, minimally coupled
scalar. We then solve the modified Dirac equation resulting from inclusion of
the self energy. We find faster-than-exponential growth in the fermion wave
function, consistent with the production of fermions through a process in which
a scalar and a fermion-anti-fermion pair are ripped out of the vacuum by
inflation.Comment: 17 pages, LaTeX 2e, 1 figure. The first 15 pages gives the text of
version 1, which matches the published version. The erratum appended on page
15 corrects a crucial sign error which COMPLETELY CHANGES THE PHYSICAL
CONCLUSION
Out-of-equilibrium evolution of quantum fields in the hybrid model with quantum back reaction
The hybrid model with a scalar "inflaton" field coupled to a "Higgs" field
with a broken symmetry potential is one of the promising models for inflation
and (p)reheating after inflation. We consider the nonequilibrium evolution of
the quantum fields of this model with quantum back reaction in the Hartree
approximation, in particular the transition of the Higgs field from the
metastable "false vacuum" to the broken symmetry phase. We have performed the
renormalization of the equations of motion, of the gap equations and of the
energy density, using dimensional regularization. We study the influence of the
back reaction on the evolution of the classical fields and of the quantum
fluctuations. We observe that back reaction plays an important role over a wide
range of parameters. Some implications of our investigation for the preheating
stage after cosmic inflation are presented.Comment: 35 pages, 16 eps figures, revtex4; v2: typos corrected and references
added, accepted for publication in Physical Review
Brane Inflation, Solitons and Cosmological Solutions: I
In this paper we study various cosmological solutions for a D3/D7 system
directly from M-theory with fluxes and M2-branes. In M-theory, these solutions
exist only if we incorporate higher derivative corrections from the curvatures
as well as G-fluxes. We take these corrections into account and study a number
of toy cosmologies, including one with a novel background for the D3/D7 system
whose supergravity solution can be completely determined. This new background
preserves all the good properties of the original model and opens up avenues to
investigate cosmological effects from wrapped branes and brane-antibrane
annihilation, to name a few. We also discuss in some detail semilocal defects
with higher global symmetries, for example exceptional ones, that could occur
in a slightly different regime of our D3/D7 model. We show that the D3/D7
system does have the required ingredients to realise these configurations as
non-topological solitons of the theory. These constructions also allow us to
give a physical meaning to the existence of certain underlying homogeneous
quaternionic Kahler manifolds.Comment: Harvmac, 115 pages, 9 .eps figures; v2: typos corrected, references
added and the last section expanded; v3: Few minor typos corrected and
references added. Final version to appear in JHE
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Energetic particle influence on the Earth's atmosphere
This manuscript gives an up-to-date and comprehensive overview of the effects of energetic particle precipitation (EPP) onto the whole atmosphere, from the lower thermosphere/mesosphere through the stratosphere and troposphere, to the surface. The paper summarizes the different sources and energies of particles, principally
galactic cosmic rays (GCRs), solar energetic particles (SEPs) and energetic electron precipitation (EEP). All the proposed mechanisms by which EPP can affect the atmosphere
are discussed, including chemical changes in the upper atmosphere and lower thermosphere, chemistry-dynamics feedbacks, the global electric circuit and cloud formation. The role of energetic particles in Earth’s atmosphere is a multi-disciplinary problem that requires expertise from a range of scientific backgrounds. To assist with this synergy, summary tables are provided, which are intended to evaluate the level of current knowledge of the effects of energetic particles on processes in the entire atmosphere
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age-and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to similar to 2.8M SNPs with BMI and WHRadjBMI in four strata (men 50y, women 50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR= 50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may providefurther insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.Peer reviewe