724 research outputs found

    Central Washington University Campus Community Garden: A Mural Project

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    This service-learning project represents the first phase of constructing a mural for the campus community garden at Central Washington University. The purpose of the mural is to bring awareness to the garden by creating a welcoming space that empowers the community to learn from, work with, and teach others. As a group, we became involved with the Campus Community Garden through a Health Education (HED) course, Community Organization and Coalition Development (HED 450). The purpose of this course is to provide public health students the knowledge, practices, and skills necessary to be successful while working with community organizations. We started out developing a concept to attract more Central Washington University students to be a part of the garden through participating in a design competition for the garden’s mural. Submitted designs from Central Washington University students are currently being considered for final selection during the month of April. The chosen artist will be asked to recreate the drawing on a plywood panel for a Community Mural Painting event which will be held on the first Friday in May, and it will be open for participation by all community members. Our role in this project was to collaborate in the launching of the mural design competition, engaging local businesses to contribute resources to the mural project, and participate in the Community Painting Event in May. Our service learning project also involved several opportunities for academic reflection on this experience, and we plan to highlight some of our reflection pieces, as well as photos from the design process, and the actual garden space in our SOURCE presentation

    Research Openness in Canadian Political Science: Toward an Inclusive and Differentiated Discussion

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    In this paper, we initiate a discussion within the Canadian political science community about research openness and its implications for our discipline.  This discussion is important because the Tri-Agency has recently released guidelines on data management and because a number of political science journals, from several subfields, have signed the Journal Editors’ Transparency Statement requiring data access and research transparency (DA-RT).  As norms regarding research openness develop, an increasing number and range of journals and funding agencies may begin to implement DA-RT-type requirements.  If Canadian political scientists wish to continue to participate in the global political science community, we must take careful note of and be proactive participants in the ongoing developments concerning research openness

    Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.

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    Stavudine (d4T) was, until recently, one of the most widely prescribed antiretroviral drugs worldwide. While there has been a major shift away from d4T use in resource-limited countries, a large number of patients have previously received (or continue to receive) d4T, and many have developed peripheral neuropathy. The identification of genetic predictors of increased risk might suggest novel therapeutic targets for such patients. In AIDS Clinical Trials Group protocol 384, antiretroviral-naïve patients were randomized to d4T/didanosine (ddI)- or zidovudine/lamivudine-containing regimens. Data from d4T/ddI recipients were analyzed for genome-wide associations (approximately 1 million genetic loci) with new onset distal sensory peripheral neuropathy. Analyses involved 254 patients (49 % White, 34 % Black, 17 % Hispanic), comprising 90 peripheral neuropathy cases (32 grade 1, 35 grade 2, 23 grade 3) and 164 controls. After correcting for multiple comparisons, no polymorphism was consistently associated with neuropathy among all patients, among White, Black, and Hispanic patients analyzed separately, both in genome-wide analyses (threshold, P < 5.0 × 10(-8)) and focused on 46 neuropathy-associated genes (threshold, P < 3.5 × 10(-5)). In the latter analyses, the lowest P values were in KIF1A among Whites (rs10199388, P = 8.4 × 10(-4)), in LITAF among Blacks (rs13333308, P = 6.0 × 10(-6)), and in NEFL among Hispanics (rs17763685, P = 5.6 × 10(-6)). Susceptibility to d4T/ddI-associated neuropathy is not explained by a single genetic variant with a marked effect

    System for Estimating Horizontal Velocity During Descent

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    The descent image motion estimation system (DIMES) is a system of hardware and software, designed for original use in estimating the horizontal velocity of a spacecraft descending toward a landing on Mars. The estimated horizontal velocity is used in generating rocket-firing commands to reduce the horizontal velocity as part of an overall control scheme to minimize the landing impact. DIMES can also be used for estimating the horizontal velocity of a remotely controlled or autonomous aircraft for purposes of navigation and control

    Derivations and automorphisms of free nilpotent Lie algebras and their quotiens

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    Let \n_{d,t} be the free nilpotent Lie algebra of type dd and nilindex tt. Starting out with the derivation algebra and the automorphism group of \n_{d,t}, we get a natural description of derivations and automorphisms of any generic nilpotent Lie algebra of the same type and nilindex. Moreover, along the paper we discuss several examples to illustrate the obtained results.Comment: 13 page

    Molecular Weight Dependence of Spreading Rates of Ultrathin Polymeric Films

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    We study experimentally the molecular weight MM dependence of spreading rates of molecularly thin precursor films, growing at the bottom of droplets of polymer liquids. In accord with previous observations, we find that the radial extension R(t) of the film grows with time as R(t) = (D_{exp} t)^{1/2}. Our data substantiate the M-dependence of D_{exp}; we show that it follows D_{exp} \sim M^{-\gamma}, where the exponent \gamma is dependent on the chemical composition of the solid surface, determining its frictional properties with respect to the molecular transport. In the specific case of hydrophilic substrates, the frictional properties can be modified by the change of the relative humidity (RH). We find that \gamma \approx 1 at low RH and tends to zero when RH gets progressively increased. We propose simple theoretical arguments which explain the observed behavior in the limits of low and high RH.Comment: 4 pages, 2 figures, to appear in PR

    UV+IR Star Formation Rates: Hickson Compact Groups with Swift and Spitzer

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    We present Swift UVOT (1600-3000A) 3-band photometry for 41 galaxies in 11 nearby (<4500km/s) Hickson Compact Groups (HCGs) of galaxies. We use the uvw2-band (2000A) to estimate the dust-unobscured component, SFR_UV, of the total star-formation rate, SFR_T. We use Spitzer MIPS 24-micron photometry to estimate SFR_IR, the dust-obscured component of SFR_T. We obtain SFR_T=SFR_UV+SFR_IR. Using 2MASS K_s band based stellar mass, M*, estimates, we calculate specific SFRs, SSFR=SFR_T/M*. SSFR values show a clear and significant bimodality, with a gap between low (<~3.2x10^-11 / yr) and high SSFR (>~1.2x10^-10 / yr) systems. All galaxies with MIR activity index a_IRAC 0) are in the high- (low-) SSFR locus, as expected if high levels of star-formation power MIR emission from polycyclic aromatic hydrocarbon molecules and a hot dust continuum. All elliptical/S0 galaxies are in the low-SSFR locus, while 22 out of 24 spirals/irregulars are in the high-SSFR locus, with two borderline cases. We divide our sample into three subsamples (I, II and III) according to decreasing HI-richness of the parent galaxy group to which a galaxy belongs. Consistent with the SSFR and a_IRAC bimodality, 12 out of 15 type-I (11 out of 12 type-III) galaxies are in the high- (low-) SSFR locus, while type II galaxies span almost the full range of SSFR values. Unlike HCG galaxies, galaxies in a comparison quiescent SINGS sub-sample are continuously distributed both in SSFR and a_IRAC. Any uncertainties can only further enhance the SSFR bimodality. These results suggest that an environment characterized by high galaxy number-densities and low galaxy velocity-dispersions, such as the one found in compact groups, plays a key role in accelerating galaxy evolution by enhancing star-formation processes in galaxies and favoring a fast transition to quiescence.(abridged)Comment: Accepted by ApJ. [8 Tables, 16 Figures. Color figures have reduced size for ArXiv - emulateapj v. 2/16/10

    Dust attenuation in disk-dominated galaxies: evidence for the 2175A dust feature

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    The attenuation of starlight by interstellar dust is investigated in a sample of low redshift, disk-dominated star-forming galaxies using photometry from GALEX and SDSS. By considering broadband colors as a function of galaxy inclination we are able to confidently separate trends arising from increasing dust opacity from possible differences in stellar populations, since stellar populations do not correlate with inclination. All commonly employed dust attenuation curves (such as the Calzetti curve for starbursts, or a power-law curve) provide poor fits to the ultraviolet colors for moderately and highly inclined galaxies. This conclusion rests on the fact that the average FUV-NUV color varies little from face-on to edge-on galaxies, while other colors such as NUV-u and u-r vary strongly with inclination. After considering a number of model variations, we are led to speculate that the presence of the strong dust extinction feature at 2175A seen in the Milky Way (MW) extinction curve is responsible for the observed trends. Independent of our interpretation, these results imply that the modeling of dust attenuation in the ultraviolet is significantly more complicated than traditionally assumed. These results also imply a very weak dependence of the FUV-NUV color on total FUV attenuation, and we conclude from this that it is extremely difficult to use only the observed UV spectral slope to infer the total UV dust attenuation, as is commonly done. We propose several simple tests that might finally identify the grain population responsible for the 2175A feature.Comment: 16 pages, 10 figures. ApJ accepte

    Porphyrin Production and Regulation in Cutaneous Propionibacteria

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    ABSTRACT Porphyrins are intermediate metabolites in the biosynthesis of vital molecules, including heme, cobalamin, and chlorophyll. Bacterial porphyrins are known to be proinflammatory, with high levels linked to inflammatory skin diseases. Propionibacterium species are dominant skin commensals and play essential roles in defending against pathogens and in triggering an inflammatory response. To better understand how the inflammatory potential of the skin microbiome may vary depending on its propionibacterial composition, we compared the production levels of porphyrins among Propionibacterium acnes, Propionibacterium granulosum, Propionibacterium avidum, and Propionibacterium humerusii strains. We found that porphyrin production varied among these species, with P. acnes type I strains producing significantly larger amounts of porphyrins than P. acnes type II and III strains and other Propionibacterium species. P. acnes strains that are highly associated with the common skin condition acne vulgaris responded to vitamin B12 supplementation with significantly higher porphyrin production. In contrast, vitamin B12 supplementation had no effect on the porphyrin production of health-associated P. acnes strains and other propionibacteria. We observed low-level porphyrin production in most Propionibacterium strains harboring the deoR repressor gene, with the exception of P. acnes strains belonging to type I clades IB-3 and IC. Our findings shed light on the proinflammatory potential of distinct phylogenetic lineages of P. acnes as well as other resident skin propionibacteria. We demonstrate that the overall species and strain composition is important in determining the metabolic output of the skin microbiome in health and disease. IMPORTANCE Porphyrins are a group of metabolites essential to the biosynthesis of heme, cobalamin, and chlorophyll in living organisms. Bacterial porphyrins can be proinflammatory, with high levels linked to human inflammatory diseases, including the common skin condition acne vulgaris. Propionibacteria are among the most abundant skin bacteria. Variations in propionibacteria composition on the skin may lead to different porphyrin levels and inflammatory potentials. This study characterized porphyrin production in all lineages of Propionibacterium acnes, the most dominant skin Propionibacterium, and other resident skin propionibacteria, including P. granulosum, P. avidum, and P. humerusii. We revealed that P. acnes type I strains produced significantly more porphyrins than did type II and III strains and other Propionibacterium species. The findings from this study shed light on the proinflammatory potential of the skin microbiome and can be used to guide the development of effective acne treatments by modulating the skin microbiome and its metabolic activities

    Hot Jupiters and the evolution of stellar angular momentum

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    Giant planets orbiting main-sequence stars closer than 0.1 AU are called hot Jupiters. They interact with their stars affecting their angular momentum. Recent observations provide suggestive evidence of excess angular momentum in stars with hot Jupiters in comparison to stars with distant and less massive planets. This has been attributed to tidal interaction, but needs to be investigated in more detail considering also other possible explanations because in several cases the tidal synchronization time scales are much longer than the ages of the stars. We select stars harbouring transiting hot Jupiters to study their rotation and find that those with an effective temperature greater than 6000 K and a rotation period shorter than 10 days are synchronized with the orbital motion of their planets or have a rotation period approximately twice that of the planetary orbital period. Stars with an effective temperature lower than 6000 K and a rotation period longer than 10 days show a general trend toward synchronization with increasing effective temperature or decreasing orbital period. We propose a model for the angular momentum evolution of stars with hot Jupiters to interpret these observations. It is based on the hypothesis that a close-in giant planet affects the coronal field of its host star leading to a topology with predominantly closed field lines. Our model can be tested observationally and has relevant consequences for the relationship between stellar rotation and close-in giant planets as well as for the application of gyrochronology to estimate the age of planet-hosting stars.Comment: 18 pages, 4 tables, 8 figures, accepted by Astronomy and Astrophysic
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