Thank you,

Public Comment on Kettleman City dump expansion Petition to stop Kettleman Hills expansion.xls Wayne, Attached is a list of people who signed our online petition opposing the expansion of the Chem Waste Kettleman Hills hazardous waste dump, with additional comments. We are submitting this as part of the public comment period for the permit. The petition was prefaced with a video and this language: "Kettleman City is a rural, majority Latino and farmworker community halfruay between Los Angeles and San Franoisco. It is home to the largest hazardous waste dump this side of the Mississippi and to shockingly high rates of childhood cancer, birth defects and miscarriages- two facts residents believe to be connected. Now the dump is looking to double in size and the agency responsible for approving the expansion- the Department of Toxic Substances Control- is letting it happen. We have until October 25th to stop this.Sign the petition to demand the Dept. of Toxic Substances Control stop the dump from expanding!&quot

Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA

Precise regulation of Egr2 transcription is fundamentally important to the control of peripheral myelination. Here, we describe a long non-coding RNA antisense to the promoter of Egr2 (Egr2-AS-RNA). During peripheral nerve injury, the expression of Egr2-AS-RNA is increased and correlates with decreased Egr2 transcript and protein levels. Ectopic expression of Egr2-AS-RNA in dorsal root ganglion (DRG) cultures inhibits the expression of Egr2 mRNA and induces demyelination. In vivo inhibition of Egr2-AS-RNA using oligonucleotide GapMers released from a biodegradable hydrogel following sciatic nerve injury reverts the EGR2-mediated gene expression profile and significantly delays demyelination. Egr2-AS-RNA gradually recruits H3K27ME3, AGO1, AGO2, and EZH2 on the Egr2 promoter following sciatic nerve injury. Furthermore, expression of Egr2-AS-RNA is regulated through ERK1/2 signaling to YY1, while loss of Ser184 of YY1 regulates binding to Egr2-AS-RNA. In conclusion, we describe functional exploration of an antisense long non-coding RNA in peripheral nervous system (PNS) biology. Keywords: nerve injury response; transcription; RNA epigenetics; antisense RNA; Egr2; myelination; YY1; neureguli

Estudio físico-químicos de los huevos de Iguana iguana Linnaeus, 1758

Caracterización físico-químicamente de huevos de Iguana iguana. Las pruebas físicas se realizaron por métodos de Espectrofotocolorimetría, calibrador, cinta métrica, micrómetro, flexómetro y flotación y las pruebas químicas acorde a los lineamientos exigidos por la A.O.A.C. Los resultados obtenidos mostraron con respecto a las características físicas: En promedio, un peso de 14,78 (g); diámetro longitudinal 39,70 mm (±0,49), diámetro transversal 26,41mm (±0,6), largo perimetral 11,55 cm (±0,2), ancho perimetral 9,07 cm (± 0,2), entre otras caractericticas evaluadas. Respecto a la composición química, en cáscara 51,23% (±3,02) Calcio Inorgánico; 20,17% (±1,56) Fósforo Inorgánico; en albumen 51,47% (±1,05) de proteína bruta, un 17,02% (±1,33) de grasa cruda y en albumen compacto un peso de 3,83 g (±0,21). Mediante regresiones múltiples se determinó que el peso depende del porcentaje de cáscara y del albumen compacto en un 87%. La gravedad específica depende no solo del largo perimetral sino también del porcentaje de cáscara y del grosor de ésta en la zona ecuatorial en un 86,3%. El porcentaje de cáscara, del peso, gravedad específica y grosor en la zona ecuatorial en 88,3%. La caracterización cromática determinó su color entre amarillo medio y blanco amarillento

Estudio físico-químicos de los huevos de Iguana iguana Linnaeus, 1758

Iguana iguana eggs were physically and chemically characterized. the physical tests were performed by methods of spectrophotolorimetry, calibrator, tape measure, micrometer, flexometer and flotation and chemical tests according to the guidelines required by A.O.A.C. The results obtained showed with respect to the physical characteristics: On average, a weight of 14.78 (g); longitudinal diameter 39.70 mm (±0.49), cross-sectional diameter 26.41mm (±0.6), perimeter length 11.55 cm (±0.2), perimeter width 9.07 cm (±02), among other characteristics evaluated. Regarding the chemical composition, in shell 51.23% (±3.02) Inorganic Calcium; 20.17% (±1.56) Inorganic Phosphorus; in albumen 51.47% (±1.05) of crude protein, 17.02% (±1.33) of raw fat and in compact albumen a weight of 3.83 g (±0.21). Through multiple regressions, it was determined that the weight depends on the percentage of shell and the compact albumen in 87%. The specific gravity depends not only on the perimeter length but also on the percentage of shell and the thickness of this in the equatorial zone in a 86.3%. The percentage of shell, weight, specific gravity and thickness in the equatorial zone in 88.3%. The chromatic characterization determined its color between medium yellow and yellowish white.Caracterización físico-químicamente de huevos de Iguana iguana. Las pruebas físicas se realizaron por métodos de Espectrofotocolorimetría, calibrador, cinta métrica, micrómetro, flexómetro y flotación y las pruebas químicas acorde a los lineamientos exigidos por la A.O.A.C. Los resultados obtenidos mostraron con respecto a las características físicas: En promedio, un peso de 14,78 (g); diámetro longitudinal 39,70 mm (±0,49), diámetro transversal 26,41mm (±0,6), largo perimetral 11,55 cm (±0,2), ancho perimetral 9,07 cm (± 0,2), entre otras caractericticas evaluadas. Respecto a la composición química, en cáscara 51,23% (±3,02) Calcio Inorgánico; 20,17% (±1,56) Fósforo Inorgánico; en albumen 51,47% (±1,05) de proteína bruta, un 17,02% (±1,33) de grasa cruda y en albumen compacto un peso de 3,83 g (±0,21). Mediante regresiones múltiples se determinó que el peso depende del porcentaje de cáscara y del albumen compacto en un 87%. La gravedad específica depende no solo del largo perimetral sino también del porcentaje de cáscara y del grosor de ésta en la zona ecuatorial en un 86,3%. El porcentaje de cáscara, del peso, gravedad específica y grosor en la zona ecuatorial en 88,3%. La caracterización cromática determinó su color entre amarillo medio y blanco amarillento

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Measurement of the t t-bar production cross section in the dilepton channel in pp collisions at sqrt(s) = 7 TeV

The t t-bar production cross section (sigma[t t-bar]) is measured in proton-proton collisions at sqrt(s) = 7 TeV in data collected by the CMS experiment, corresponding to an integrated luminosity of 2.3 inverse femtobarns. The measurement is performed in events with two leptons (electrons or muons) in the final state, at least two jets identified as jets originating from b quarks, and the presence of an imbalance in transverse momentum. The measured value of sigma[t t-bar] for a top-quark mass of 172.5 GeV is 161.9 +/- 2.5 (stat.) +5.1/-5.0 (syst.) +/- 3.6(lumi.) pb, consistent with the prediction of the standard model.Comment: Replaced with published version. Included journal reference and DO

Search for anomalous t t-bar production in the highly-boosted all-hadronic final state

A search is presented for a massive particle, generically referred to as a Z', decaying into a t t-bar pair. The search focuses on Z' resonances that are sufficiently massive to produce highly Lorentz-boosted top quarks, which yield collimated decay products that are partially or fully merged into single jets. The analysis uses new methods to analyze jet substructure, providing suppression of the non-top multijet backgrounds. The analysis is based on a data sample of proton-proton collisions at a center-of-mass energy of 7 TeV, corresponding to an integrated luminosity of 5 inverse femtobarns. Upper limits in the range of 1 pb are set on the product of the production cross section and branching fraction for a topcolor Z' modeled for several widths, as well as for a Randall--Sundrum Kaluza--Klein gluon. In addition, the results constrain any enhancement in t t-bar production beyond expectations of the standard model for t t-bar invariant masses larger than 1 TeV.Comment: Submitted to the Journal of High Energy Physics; this version includes a minor typo correction that will be submitted as an erratu

Combined search for the quarks of a sequential fourth generation

Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO

Measurement of the Z/gamma* + b-jet cross section in pp collisions at 7 TeV

The production of b jets in association with a Z/gamma* boson is studied using proton-proton collisions delivered by the LHC at a centre-of-mass energy of 7 TeV and recorded by the CMS detector. The inclusive cross section for Z/gamma* + b-jet production is measured in a sample corresponding to an integrated luminosity of 2.2 inverse femtobarns. The Z/gamma* + b-jet cross section with Z/gamma* to ll (where ll = ee or mu mu) for events with the invariant mass 60 < M(ll) < 120 GeV, at least one b jet at the hadron level with pT > 25 GeV and abs(eta) < 2.1, and a separation between the leptons and the jets of Delta R > 0.5 is found to be 5.84 +/- 0.08 (stat.) +/- 0.72 (syst.) +(0.25)/-(0.55) (theory) pb. The kinematic properties of the events are also studied and found to be in agreement with the predictions made by the MadGraph event generator with the parton shower and the hadronisation performed by PYTHIA.Comment: Submitted to the Journal of High Energy Physic