Relationship between CMJ and change of direction in collective sports

En la ejecución de una carrera a máxima velocidad con cambio de dirección observamos una alta participación de componentes de fuerza. Dichos componentes vienen siendo entrenados de forma específica, como por ejemplo a través de la pliometría. Pocos estudios valoran la fuerza explosiva y reactiva de forma unilateral y su correlación con las carreras cortas de aceleración con cambios de dirección. Según los resultados de los trabajos revisados, nuestro propósito es conocer la relación entre medidas de fuerza-explosiva y fuerza reactiva, con carreras cortas de aceleración con cambios de dirección, para determinar si la manifestación de fuerza con un salto con contramovimiento (CMJ) predice el rendimiento en carreras cortas de aceleración con cambios de dirección de 90º

Efectos del desentrenamiento sobre los valores antropométricos en jóvenes futbolistas

When executing a race at full speed with change-of-direction force components are highly involved. These components are being specifically trained through plyometric exercises, among others. Few studies evaluate on one side explosive and reactive strength (1,2) and their correlation with short change-of-direction sprints. Once analyzed the evidences showed in some studies reviewed (3,4,5,6,7), our purpose is to determine the relationship between both explosive and reactive strength measures and short change-of-direction sprints in order to find whether the countermovement jump (CMJ) force manifestation helps predicting the performance level during change-of-direction 90º acceleration sprints.El desentrenamiento ha sido definido (Mújika et al., 2001a) como pérdida parcial o completa de las adaptaciones fisiológicas, anatómicas y del rendimiento conseguido con el entrenamiento y como una consecuencia de la reducción o suspensión del proceso de entrenamiento. Con este estudio pretendemos evaluar la influencia del desentrenamiento sobre las variables antropométricas en jóvenes futbolistas (13-15 años). Los resultados nos muestran que las variables antropométricas son una herramienta exacta evaluable en futbolistas en formació

Relación entre el CMJ y cambios de dirección en deportes colectivos

When executing a race at full speed with change-of-direction force components are highly involved. These components are being specifically trained through plyometric exercises, among others. Few studies evaluate on one side explosive and reactive strength (1,2) and their correlation with short change-of-direction sprints. Once analyzed the evidences showed in some studies reviewed (3,4,5,6,7), our purpose is to determine the relationship between both explosive and reactive strength measures and short change-of-direction sprints in order to find whether the countermovement jump (CMJ) force manifestation helps predicting the performance level during change-of-direction 90º acceleration sprints.En la ejecución de una carrera a máxima velocidad con cambio de dirección observamos una alta participación de componentes de fuerza. Dichos componentes vienen siendo entrenados de forma específica, como por ejemplo a través de la pliometría. Pocos estudios valoran la fuerza explosiva y reactiva de forma unilateral (1,2) y su correlación con las carreras cortas de aceleración con cambios de dirección. Según los resultados de los trabajos revisados, (3,4,5,6,7) nuestro propósito es conocer la relación entre medidas de fuerza-explosiva y fuerza reactiva, con carreras cortas de aceleración con cambios de dirección, para determinar si la manifestación de fuerza con un salto con contramovimiento (CMJ) predice el rendimiento en carreras cortas de aceleración con cambios de dirección de 90º

Exploring the canonical behaviour of long gamma-ray bursts using an intrinsic multiwavelength afterglow correlation

In this paper, we further investigate the relationship, reported by Oates et al., between the optical/UV afterglow luminosity (measured at restframe 200 s) and average afterglow decay rate (measured from restframe 200 s onwards) of long duration gamma-ray bursts (GRBs). We extend the analysis by examining the X-ray light curves, finding a consistent correlation. We therefore explore how the parameters of these correlations relate to the prompt emission phase and, using a Monte Carlo simulation, explore whether these correlations are consistent with predictions of the standard afterglow model. We find significant correlations between: log  LO, 200 s and log  LX, 200 s; αO, >200 s and αX, >200 s, consistent with simulations. The model also predicts relationships between log Eiso and log  L200 s; however, while we find such relationships in the observed sample, the slope of the linear regression is shallower than that simulated and inconsistent at ≳3σ. Simulations also do not agree with correlations observed between log  L200 s and α> 200 s, or logEiso logEiso and α> 200 s. Overall, these observed correlations are consistent with a common underlying physical mechanism producing GRBs and their afterglows regardless of their detailed temporal behaviour. However, a basic afterglow model has difficulty explaining all the observed correlations. This leads us to briefly discuss alternative more complex models

Exploring the canonical behaviour of long gamma-ray bursts with an intrinsic multiwavelength afterglow correlation

In this conference proceeding we examine a correlation between the afterglow luminosity (measured at restframe 200 s; logL200s) and average afterglow decay rate (measured from restframe 200 s onwards; α>200s) found in both the optical/UV and X-ray afterglows of long duration Gamma-ray Bursts (GRBs). Examining the X-ray light curves, we find the correlation does not depend on the presence of specific light curve features. We explore how the parameters in the optical/UV and X-ray bands relate to each other and to the prompt emission phase. We also use a Monte Carlo simulation to explore whether these relationships are consistent with predictions of the standard afterglow model. We conclude that the correlations are consistent with a common underlying physical mechanism producing GRBs and their afterglows regardless of their detailed temporal behaviour. However, a basic afterglow model has difficulty explaining correlations involving α>200s. We therefore briefly discuss alternative more complex models

Lithium and boron in calcified tissues of vicuna and its relation to the chronic exposure by water ingestion in the Andean lithium triangle

Vicuna is a wild, endangered species of Andean camelid living in the hyperarid Andean plateau. In the central part of the plateau, the Lithium Triangle defines a zone with lithium‐rich salt pans. Brine pools naturally form within the salt pans, and the adaptation strategy of vicuna consists of drinking from brine pools. Together with reporting the first chemical data on vicuna bones and teeth, we analyzed lithium, boron, and arsenic in water and brines, with the aim of assessing their relation to chronic exposure by water ingestion. We collected and analyzed bones of vicuna specimens lying in an Andean salt pan, together with brine and water samples. Brine and water samples are highly saline and contain large amounts of lithium, boron, and arsenic. Lithium (13.50–40 mg kg–1 ) and boron (40–46.80 mg kg–1 ), but not arsenic, were found in the vicuna bones and teeth. Based on our results and on previously reported data on human tissues in the Andes, we conducted statistical assessments of the relationships between lithium and boron in body tissues and water samples, and discuss their environmental significance in the context of the Lithium Triangle.Fil: López Steinmetz, Romina Lucrecia. Universidad Nacional de Jujuy. Instituto de Ecorregiones Andinas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Ecorregiones Andinas; Argentina. Universidad Nacional de Jujuy. Instituto de Geología Minera; ArgentinaFil: Fong, Shao Bing. University of Melbourne; AustraliaFil: Boyer, Emile. Universite de Rennes I; FranciaFil: López Steinmetz, Lorena Cecilia. Universidad Nacional de Córdoba. Instituto de Investigaciones Psicológicas. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Psicológicas; ArgentinaFil: Tejerina, Norberto Elio. Universidad Nacional de Jujuy. Instituto de Geología Minera; ArgentinaFil: Meuric, Vincent. Universite de Rennes I; Franci

The Host Galaxy of OJ 287 Revealed by Optical and Near-infrared Imaging

The BL Lacertae object OJ 287 (z = 0.306) has unique double-peaked optical outbursts every similar to 12 yr, and it presents one of the best cases for a small-separation binary supermassive black hole (SMBH) system, with an extremely massive primary log (M-BH/M-circle dot). However, the host galaxy is unresolved or only marginally detected in all optical studies so far, indicating a large deviation from the bulge mass-SMBH mass relation. We have obtained deep, high spatial resolution i-band and K-band images of OJ 287 when the target was in a low state, which enable us to detect the host galaxy. We find the broadband photometry of the host to be consistent with an early-type galaxy with M-R = -22.5 and M-K = -25.2, placing it in the middle of the host galaxy luminosity distribution of BL Lacertae objects. The central supermassive black hole is clearly overmassive for a host galaxy of that luminosity, but not unprecedented, given some recent findings of other "overmassive" black holes in nearby galaxies

IGF1R Signaling in Ewing Sarcoma Is Shaped by Clathrin-/Caveolin-Dependent Endocytosis

Receptor endocytosis is critical for cell signaling. IGF1R mediates an autocrine loop that is de-regulated in Ewing Sarcoma (ES) cells. Here we study the impact of IGF1R internalization, mediated by clathrin and caveolin-1 (CAV1), in ES signaling. We used clathrin and CAV1-siRNA to interfere in clathrin- and caveolin-dependent endocytosis. Chlorpromazine (CPMZ) and methyl-beta-cyclo-dextrin (MCD) were also used in order to inhibit clathrin- and caveolin-dependent endocytosis, respectively. We analyzed IGF1R internalization and co-localization with clathrin and CAV1 upon ligand binding, as well as the status of the IGF1R pathway, cellular proliferation, and the apoptosis of interfered and inhibited ES cells. We performed a high-throughput tyrosine kinase phosphorylation assay to analyze the effects of combining the IGF1R tyrosine kinase inhibitor AEW541 (AEW) with CPMZ or MCD on the intracellular phospho-proteome. We observed that IGF1R is internalized upon ligand binding in ES cells and that this process is dependent on clathrin or CAV1. The blockage of receptor internalization inhibited AKT and MAPK phosphorylation, reducing the proliferative rate of ES cells and increasing the levels of apoptosis. Combination of AEW with CPMZ or MCD largely enhanced these effects. CAV1 and clathrin endocytosis controls IGF1R internalization and signaling and has a profound impact on ES IGF1R-promoted survival signaling. We propose the combination of tyrosine-kinase inhibitors with endocytosis inhibitors as a new therapeutic approach to achieve a stronger degree of receptor inhibition in this, or other neoplasms dependent on IGF1R signaling

Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium

Clostridium autoethanogenum is an acetogenic bacterium capable of producing high value commodity chemicals and biofuels from the C1 gases present in synthesis gas. This common industrial waste gas can act as the sole energy and carbon source for the bacterium that converts the low value gaseous components into cellular building blocks and industrially relevant products via the action of the reductive acetyl-CoA (Wood-Ljungdahl) pathway. Current research efforts are focused on the enhancement and extension of product formation in this organism via synthetic biology approaches. However, crucial to metabolic modelling and directed pathway engineering is a reliable and comprehensively annotated genome sequence

Perceived economic self‑sufficiency: a countryand generation‑comparative approach

We thank Michael Camasso and Radha Jagannathan as well as Asimina Christoforou, Gerbert Kraaykamp, Fay Makantasi, Tiziana Nazio, Kyriakos Pierrakakis, Jacqueline O’Reilly and Jan van Deth for their contribution to the CUPESSE project (Seventh Framework Programme; Grant Agreement No. 61325). CUPESSE received additional funding from the Mannheim Centre for European Social Research (MZES) and the Field of Focus 4 “Self-Regulation and Regulation: Individuals and Organisations” at Heidelberg University. We further acknowledge helpful comments on this article by two anonymous reviewers. Julian Rossello provided valuable research assistance.Electronic supplementary material The online version of this article (https ://doi.org/10.1057/ s4130 4-018-0186-3) contains supplementary material, which is available to authorized users.Existing datasets provided by statistical agencies (e.g. Eurostat) show that the economic and financial crisis that unfolded in 2008 significantly impacted the lives and livelihoods of young people across Europe. Taking these official statistics as a starting point, the collaborative research project “Cultural Pathways to Economic Self-Sufficiency and Entrepreneurship in Europe” (CUPESSE) generated new survey data on the economic and social situation of young Europeans (18–35 years). The CUPESSE dataset allows for country-comparative assessments of young people’s perceptions about their socio-economic situation. Furthermore, the dataset includes a variety of indicators examining the socio-economic situation of both young adults and their parents. In this data article, we introduce the CUPESSE dataset to political and social scientists in an attempt to spark a debate on the measurements, patterns and mechanisms of intergenerational transmission of economic self-sufficiency as well as its political implications.CUPESSE project (Seventh Framework Programme; Grant Agreement No. 61325