169 research outputs found

    Can dissonance engineering improve risk analysis of human–machine systems?

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    The paper discusses dissonance engineering and its application to risk analysis of human–machine systems. Dissonance engineering relates to sciences and technologies relevant to dissonances, defined as conflicts between knowledge. The richness of the concept of dissonance is illustrated by a taxonomy that covers a variety of cognitive and organisational dissonances based on different conflict modes and baselines of their analysis. Knowledge control is discussed and related to strategies for accepting or rejecting dissonances. This acceptability process can be justified by a risk analysis of dissonances which takes into account their positive and negative impacts and several assessment criteria. A risk analysis method is presented and discussed along with practical examples of application. The paper then provides key points to motivate the development of risk analysis methods dedicated to dissonances in order to identify the balance between the positive and negative impacts and to improve the design and use of future human–machine system by reinforcing knowledge

    Integrating isotopes and documentary evidence : dietary patterns in a late medieval and early modern mining community, Sweden

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    We would like to thank the Archaeological Research Laboratory, Stockholm University, Sweden and the Tandem Laboratory (Ångström Laboratory), Uppsala University, Sweden, for undertaking the analyses of stable nitrogen and carbon isotopes in both human and animal collagen samples. Also, thanks to Elin Ahlin Sundman for providing the ÎŽ13C and ÎŽ15N values for animal references from VĂ€sterĂ„s. This research (BĂ€ckström’s PhD employment at Lund University, Sweden) was supported by the Berit Wallenberg Foundation (BWS 2010.0176) and Jakob and Johan Söderberg’s foundation. The ‘Sala project’ (excavations and analyses) has been funded by Riksens Clenodium, Jernkontoret, Birgit and Gad Rausing’s Foundation, SAU’s Research Foundation, the Royal Physiographic Society of Lund, Berit Wallenbergs Foundation, Åke Wibergs Foundation, Lars Hiertas Memory, Helge Ax:son Johnson’s Foundation and The Royal Swedish Academy of Sciences.Peer reviewedPublisher PD

    Identification of a new European rabbit IgA with a serine-rich hinge region

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    <div><p>In mammals, the most striking IgA system belongs to Lagomorpha. Indeed, 14 IgA subclasses have been identified in European rabbits, 11 of which are expressed. In contrast, most other mammals have only one IgA, or in the case of hominoids, two IgA subclasses. Characteristic features of the mammalian IgA subclasses are the length and amino acid sequence of their hinge regions, which are often rich in Pro, Ser and Thr residues and may also carry Cys residues. Here, we describe a new IgA that was expressed in New Zealand White domestic rabbits of <i>IGHV</i>a1 allotype. This IgA has an extended hinge region containing an intriguing stretch of nine consecutive Ser residues and no Pro or Thr residues, a motif exclusive to this new rabbit IgA. Considering the amino acid properties, this hinge motif may present some advantage over the common IgA hinge by affording novel functional capabilities. We also sequenced for the first time the IgA14 CH2 and CH3 domains and showed that IgA14 and IgA3 are expressed.</p></div

    Impact of pulsed direct current on embryos, larvae, and young juveniles of Atlantic cod and its implications for electrotrawling of brown shrimp

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    The application of electrical pulses in fishing gear is considered a promising option to increase the sustainability of demersal trawl fisheries. In the electrotrawl fishery for brown shrimp Crangon crangon, an electrical field selectively induces a startle response in the shrimp. Other benthic organisms remain mainly on the seafloor and escape underneath a hovering trawl. Previous experiments have indicated that this pulse has no short-term major harmful effects on adult fish and invertebrates. However, the impact on young marine life stages is still unknown. Because brown shrimp are caught in shallow coastal zones and estuaries, which serve as important nurseries or spawning areas for a wide range of marine species, electrotrawling on these grounds could harm embryos, larvae, and juveniles. We carried out experiments with different developmental stages of Atlantic Cod Gadus morhua, which are considered vulnerable to electrical pulses. Three embryonic stages, four larval stages, and one juvenile stage of Atlantic Cod were exposed to a homogeneous electrical field of 150 V-peak/m for 5 s, mimicking a worst-case scenario. We detected no significant differences in embryo mortality rate between control and exposed groups. However, for the embryonic stage exposed at 18 d postfertilization, the initial hatching rate was lower. Larvae that were exposed at 2 and 26 d posthatch exhibited higher mortality rates than the corresponding nonexposed control groups. In the other larval and juvenile stages, no short-term impact of exposure on survival was observed. Morphometric analysis of larvae and juveniles revealed no differences in measurements or deformations of the yolk, notochord, eye, or head. Although exposure to a worst-case electrical field did not impact survival or development for six of the eight young life stages of Atlantic Cod, the observed delayed hatching rate and decreased survival for larvae might indicate an impact of electric pulses and warrant further research

    Influence of fore-arc structure on the extent of great subduction zone earthquakes

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    Author Posting. © American Geophysical Union, 2007. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 112 (2007): B09301, doi:10.1029/2007JB004944.Structural features associated with fore-arc basins appear to strongly influence the rupture processes of large subduction zone earthquakes. Recent studies demonstrated that a significant percentage of the global seismic moment release on subduction zone thrust faults is concentrated beneath the gravity lows resulting from fore-arc basins. To better determine the nature of this correlation and to examine its effect on rupture directivity and termination, we estimated the rupture areas of a set of Mw 7.5–8.7 earthquakes that occurred in circum-Pacific subduction zones. We compare synthetic and observed seismograms by measuring frequency-dependent amplitude and arrival time differences of the first orbit Rayleigh waves. At low frequencies, the amplitude anomalies primarily result from the spatial and temporal extent of the rupture. We then invert the amplitude and arrival time measurements to estimate the second moments of the slip distribution which describe the rupture length, width, duration, and propagation velocity of each earthquake. Comparing the rupture areas to the trench-parallel gravity anomaly (TPGA) above each rupture, we find that in 11 of the 15 events considered in this study the TPGA increases between the centroid and the limits of the rupture. Thus local increases in TPGA appear to be related to the physical conditions along the plate interface that favor rupture termination. Owing to the inherently long timescales required for fore-arc basin formation, the correlation between the TPGA field and rupture termination regions indicates that long-lived material heterogeneity rather than short timescale stress heterogeneities are responsible for arresting most great subduction zone ruptures.A. Llenos was supported by a National Defense Science and Engineering Graduate fellowship

    Palaeogenomics of Upper Palaeolithic to Neolithic European hunter-gatherers

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    Modern humans have populated Europe for more than 45,000 years1,2. Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period3. Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. We identify a genetic ancestry profile in individuals associated with Upper Palaeolithic Gravettian assemblages from western Europe that is distinct from contemporaneous groups related to this archaeological culture in central and southern Europe4, but resembles that of preceding individuals associated with the Aurignacian culture. This&nbsp;ancestry profile survived during the Last Glacial Maximum (25,000 to 19,000 years ago) in human populations from southwestern Europe associated with the Solutrean&nbsp;culture, and with&nbsp;the following Magdalenian culture&nbsp;that re-expanded northeastward after the Last Glacial Maximum. Conversely, we reveal a genetic turnover in southern Europe suggesting a local replacement of human groups around the time of the Last Glacial Maximum, accompanied by a north-to-south dispersal of populations associated with the Epigravettian culture. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. After a period of limited admixture that spanned the beginning of the Mesolithic, we find genetic interactions between western and eastern European hunter-gatherers,&nbsp;who were also characterized by marked differences in phenotypically relevant variants

    The origins and development of Zuwīla, Libyan Sahara: an archaeological and historical overview of an ancient oasis town and caravan centre

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    ZuwÄ«la in southwestern Libya (Fazzān) was one of the most important early Islamic centres in the Central Sahara, but the archaeological correlates of the written sources for it have been little explored. This paper brings together for the first time a detailed consideration of the relevant historical and archaeological data, together with new AMS radiocarbon dates from several key monuments. The origins of the settlement at ZuwÄ«la were pre-Islamic, but the town gained greater prominence in the early centuries of Arab rule of the Maghrib, culminating with the establishment of an Ibāឍī state ruled by the dynasty of the BanĆ« Khaáč­áč­Äb, with ZuwÄ«la its capital. The historical sources and the accounts of early European travellers are discussed and archaeological work at ZuwÄ«la is described (including the new radiocarbon dates). A short gazetteer of archaeological monuments is provided as an appendix. Comparisons and contrasts are also drawn between ZuwÄ«la and other oases of the ash-Sharqiyāt region of Fazzān. The final section of the paper presents a series of models based on the available evidence, tracing the evolution and decline of this remarkable site
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