12 research outputs found
Utilisation of an operative difficulty grading scale for laparoscopic cholecystectomy
- Author
- Aawsaj Y
- Abayomi M
- Acharya V
- Aggarwal SK
- Ahmad A
- Ahmed I
- Ahmed J
- Ahmed J
- Ahmed T
- Ainley P
- Akhtar M
- Al Amari K
- Al-Abed YA
- Al-Akash M
- Al-Bahrani AZ
- Al-Khyatt W
- Al-Muhktar A
- Al-Sarireh B
- Al-Taan O
- Alagaratnam S
- Alam I
- Alberts J
- Alderson D
- Aldridge RC
- Aleksandrov D
- Ali H
- Ali S
- Amin K
- Andrew DR
- Appleton S
- Arhi C
- Aroori S
- Aryal K
- Asad M
- Aseem R
- Asprou FM
- Awan A
- Ayaani S
- Aymon
- Babu BI
- Bajwa DS
- Bajwa FM
- Baker AL
- Balfe P
- Ball WR
- Ballance L
- Banwell V
- Barnes J
- Barrie J
- Bartlett F
- Basheer M
- Bashir G
- Basra M
- Basu S
- Basynat P
- Batt J
- Bausbacher H
- Bawa S
- Beasley WD
- Belding R
- Bellini MI
- Bennett SP
- Bhandari CTS
- Bhattacharya V
- Blane C
- Blazeby JM
- Boal M
- Boddy A
- Boland M
- Bond-Smith G
- Booth MI
- Borowski DW
- Bowen L
- Boyce KM
- Boyd AT
- Bradley D
- Bradley N
- Brennan S
- Brett D
- Broadhurst J
- Brooke E
- Brown TH
- Bryant A
- Buchan J
- Bullen N
- Bunnell C
- Bunting DM
- Burke P
- Byrne JP
- Byrnes CK
- Campbell W
- Carney K
- Carney K
- Carroll P
- Carter CR
- Carter NC
- Carty N
- Cassidy JT
- Chambers A
- Chambers A
- Chambers A
- Chan WM
- Chang J
- Charalabopoulos A
- Chauhan N
- Cheung M
- Chishti IA
- Chitre V
- CholeS Study Grp
- CholeS Study Grp
- CholeS Study Grp
- CholeS Study Grp
- Choy A
- Cieplucha K
- Clements JM
- Coats M
- Cockbain AJ
- Coe PO
- Connelly M
- Cooke F
- Courtney MJ
- Cowley JB
- Cross KS
- Cuming T
- Cunha P
- D'Costa C
- Dalgaty F
- Dar F
- Date R
- Dave RV
- Davey P
- Davies J
- Dawson S
- De Marchi JA
- de Siqueira J
- Deguara J
- Delisle TG
- Dennison AR
- Derbyshire L
- Devoto L
- Dhillon A
- Diamond T
- Dickson-Lowe R
- Digney R
- Dindyal S
- Dobbins B
- Doe M
- Dorrian E
- Doulias T
- Downing J
- Downing J
- Drake B
- Driscoll PJ
- Duke D
- Durkin D
- Dwerryhouse SJ
- Ebdewi H
- Ebied H
- Eisawi A
- El-Dhuwaib APY
- El-Hasani SS
- Elkheir N
- Elmasry M
- Elsayed M
- Elshaer M
- Emesih S
- Farag SF
- Farooq A
- Farouk M
- Fasih T
- Fawole AS
- Fenwick S
- Ferguson G
- Ferris P
- Finch D
- Finch JG
- Finch JG
- Finlay I
- Fleming K
- Fletcher T
- Fordham IJ
- Forouzanfar A
- Forrest CR
- Forster L
- Fothergill L
- Frame RJ
- Francombe J
- Frank L
- Fusai G
- Galanopoulos G
- Gallagher PV
- Garcea G
- Gardner-Thorpe J
- Geoghegan JG
- Geogloma I
- Gerakopoulos S
- Ghareeb E
- Ghazanfar MA
- Gibson S
- Giles M
- Giovinazzo F
- Giwa L
- Goh YL
- Gopalswamy S
- Goscimski A
- Gossage JA
- Gough M
- Gould L
- Gould L
- Grant AJ
- Gravante G
- Griffiths EA
- Griffiths EA
- Gull S
- Gunasekera RT
- Gurung K
- Guthrie GJK
- Hafiz S
- Halkias C
- Hall C
- Hamady Z
- Hamdan A
- Hamdan MF
- Hamilton E
- Hancorn K
- Haque M
- Haque SU
- Hardy TJ
- Hargreaves A
- Harilingam ACM
- Harris A
- Harrison E
- Hawkins H
- Heath J
- Hebbar M
- Henderson LT
- Henley N
- Heshaishi M
- Hewes J
- Hewes JC
- Heywood N
- Higgs SM
- Hill ADK
- Hill ADK
- Hindley C
- Hirst NA
- Hisham E
- Ho W-M
- Hoban JR
- Hodgkins KA
- Hodson J
- Holroyd DJ
- Hooks G
- Hopwood B
- Hornby ST
- Hornsby J
- Hosie KB
- Hosie KB
- Hossack MR
- Hossain T
- Hoti E
- Hou D
- Hrycaiczuk A
- Hughes M
- Hunter DI
- Hussain A
- Hussain A
- Hussain AA
- Hussain N
- Iftikhar SY
- Iqbal N
- Iskandar E
- Issa E
- Ivanovski I
- Jackson A
- Jackson C
- Jafferbhoy SF
- Jambulingam P
- Jamdar S
- Jamel S
- Janeczko A
- Jaunoo S
- Jayanthi NVG
- Jelley C
- Jennings NA
- Joel A
- Johnpulle MA
- Johnston D
- Johnstone M
- Johnstone M
- Joji N
- Jones C
- Jones E
- Jones GH
- Jones MA
- Jones MJ
- Jones RP
- Jones SM
- Kadhim A
- Kadirkamanathan S
- Kallaway C
- Kanakala V
- Kanavati O
- Kansal N
- Kaptanis S
- Karavadra B
- Karim L
- Karunakaran P
- Katbeh T
- Kaur P
- Kausar A
- Kelly ME
- Kendal C
- Kennedy D
- Kenny R
- Keogh K
- Khalil AM
- Khan A
- Khan MA
- Khan MAS
- Khan RB
- Khan S
- Khan S
- Khawaja A
- Khawaja Z
- Khogali E
- Kimble A
- Kinghorn A
- Kirkham AJ
- Knight B
- Knight K
- Kourkulos M
- Krysztopik R
- Kumar P
- Kynaston J
- Kyriakidis D
- Lalla K
- Lambert J
- Lammy S
- Lane R
- Larkin D
- Law J
- Lawther R
- Lazim T
- Lee K
- Lee M
- Leeder P
- Lennon H
- Lewis M
- Lim HCC
- Lim PJ
- Lindsay D
- Lloyd D
- Lo C
- Lodhia J
- Longbotham DA
- Loughlin P
- Lovett B
- Luhmann A
- Luther AA
- Lyons EM
- Macano CAW
- MacArtney M
- Macdonald A
- Madanipour S
- Madbak K
- Madurska M
- Magee CJ
- Maguire D
- Maharaj G
- Majeed A
- Malcolm C
- Malde D
- Malik NS
- Mallik M
- Mansour S
- Manu M
- Manzelli A
- Marriott P
- Marriott P
- Martin J
- Martin S
- Martin ST
- Marudanayagam R
- Mason D
- Mathur P
- Mawhinney A
- Mbuvi J
- McAree B
- McCain S
- McCallum IJD
- McClarey A
- McCune K
- McDermott F
- McEntee GP
- McGlone ER
- McGuigan A
- McIlmunn C
- McKay D
- McKenzie S
- McNair AGK
- Mealy K
- Menzies D
- Mercer SJ
- Milburn J
- Mirza AK
- Mirza D
- Miu V
- Mockford KA
- Mohamed S
- Mohan HM
- Mok KWJ
- Monk D
- Morcous P
- Morrison TEM
- Mothe BS
- Mowbray N
- Mozolowski KL
- Mukherjee D
- Murphy JO
- Murtaza G
- Nally DM
- Napetti S
- Nassar AH
- Nassar AHM
- Naumann D
- Nedujchelyn Y
- Needham PJ
- Newton K
- Newton RC
- Ngu WS
- Nicholson GA
- Nicholson J
- Nicholson JA
- Nicol L
- Nicolay CR
- Nieto T
- Nijjar RS
- Nilsen-Nunn A
- Nilsson F
- Noble F
- Nofal E
- Noor N
- Nunes QM
- O'Dwyer P
- O'Neill MA
- O'Neill S
- O'Reilly DA
- O'shea KM
- O'Sullivan AW
- Obeidallah MR
- Ogedegbe A
- Old OJ
- Orchard P
- Orizu MN
- Packer JR
- Padwick R
- Panteleimonitis S
- Parappally CP
- Parmar J
- Pasquali S
- Patel A
- Patel K
- Patel S
- Pati P
- Pearce B
- Pearson KL
- Peirce C
- Pellen M
- Peter MB
- Peterson M
- Pezzuto R
- Photi E
- Phull M
- Pinho-Gomes AC
- Pollock S
- Popplewell M
- Pore N
- Porter J
- Prasad AR
- Prasad R
- Preston SR
- Preziosi G
- Prince S
- Psica A
- Puig S
- Puntis DJ
- Puri Y
- Qandeel H
- Rabie M
- Radwan R
- Rae DM
- Rahman S
- Rajaganeshan R
- Rajendran I
- Ramage MI
- Rao STV
- Rate AJ
- Raza S
- Read E
- Reddy M
- Reece-Bolton O
- Reed J
- Reid A
- Rengifo C
- Rhys T
- Richards CH
- Riera M
- Ritchie J
- Robb W
- Roberts GP
- Robinson S
- Robinson S
- Robinson SJ
- Rodriguez D
- Rodriguez DU
- Roebuck A
- Rogers PN
- Rolph RC
- Roy S
- Rutherford CL
- Sadat MM
- Sakai N
- Sampat K
- Samuel N
- Sarmah PB
- Sarvananthan K
- Sarveswaran J
- Satheesan S
- Saunders M
- Sayegh M
- Segaran A
- Sekhar H
- Sen G
- Seymour K
- Shabo W
- Shah N
- Shah R
- Shahin Y
- Sheel ARG
- Shenoy H
- Shetty V
- Shier D
- Shingler GM
- Shiwani MH
- Shrestha AK
- Siddiqi N
- Siddiqui MN
- Siddiqui Z
- Sillo TO
- Silva M
- Simpson DJ
- Singh S
- Singh-Ranger D
- Sinha S
- Skelly BL
- Slavin JP
- Slawinski C
- Sloane J
- Smith SR
- Smith SR
- Spearman J
- Spence G
- Spreadborough P
- Spreadborough P
- Starmer BZ
- Stevenson TEJ
- Stewart DJ
- Stirland E
- Subramanium D
- Sufi PA
- Sukha A
- Sutcliffe R
- Suttie S
- Sutton CMLR
- Szentpali K
- Tang C-B
- Tanner N
- Tate S
- Tayeh S
- Taylor GW
- Teasdale RL
- Templeton A
- Terrace J
- Thakkar R
- Thomas G
- Thompson RLE
- Tilston MP
- Toh SKC
- Tolofari S
- Tomlinson MA
- Trevatt AEJ
- Trotter M
- Tsang A
- Tsavellas G
- Tuck L
- Turner P
- Tutton MG
- Ullah MF
- Upchurch EA
- Urbonas T
- Varghase J
- Vass DG
- Vaughan EM
- Vijay V
- Vijayan D
- Vijayanand D
- Villatoro E
- Virupaksha S
- Vitone LJ
- Vohra RS
- Vohra RS
- Wadley M
- Wainwright D
- Wajed S
- Wallace T
- Wardle S
- Warren C
- Watkin H
- Watson AJM
- Watson NF
- Wayman J
- Weaver S
- Weber B
- Weber B
- Weerasinghe C
- Welbourn H
- West Midlands Research Collaborative
- Wheatley K
- White TJ
- Wijetunga I
- Wild JRL
- Wilkinson MD
- Williams SV
- Williamson TK
- Willson PD
- Wilson MSJ
- Wilson TR
- Winter DC
- Winter H
- Wood CPJ
- Wood P
- Wood S
- Woodman T
- Yahya S
- Yao C
- Yeldham G
- Yoganathan T
- Youssef H
- Zafar S
- Zafrani Z
- Zarsadias P
- Zeeshan S
- Zhang C
- Zino S
- Ziprin P
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background
A reliable system for grading operative difficulty of laparoscopic cholecystectomy would standardise description of findings and reporting of outcomes. The aim of this study was to validate a difficulty grading system (Nassar scale), testing its applicability and consistency in two large prospective datasets.
Methods
Patient and disease-related variables and 30-day outcomes were identified in two prospective cholecystectomy databases: the multi-centre prospective cohort of 8820 patients from the recent CholeS Study and the single-surgeon series containing 4089 patients. Operative data and patient outcomes were correlated with Nassar operative difficultly scale, using Kendall’s tau for dichotomous variables, or Jonckheere–Terpstra tests for continuous variables. A ROC curve analysis was performed, to quantify the predictive accuracy of the scale for each outcome, with continuous outcomes dichotomised, prior to analysis.
Results
A higher operative difficulty grade was consistently associated with worse outcomes for the patients in both the reference and CholeS cohorts. The median length of stay increased from 0 to 4 days, and the 30-day complication rate from 7.6 to 24.4% as the difficulty grade increased from 1 to 4/5 (both p < 0.001). In the CholeS cohort, a higher difficulty grade was found to be most strongly associated with conversion to open and 30-day mortality (AUROC = 0.903, 0.822, respectively). On multivariable analysis, the Nassar operative difficultly scale was found to be a significant independent predictor of operative duration, conversion to open surgery, 30-day complications and 30-day reintervention (all p < 0.001).
Conclusion
We have shown that an operative difficulty scale can standardise the description of operative findings by multiple grades of surgeons to facilitate audit, training assessment and research. It provides a tool for reporting operative findings, disease severity and technical difficulty and can be utilised in future research to reliably compare outcomes according to case mix and intra-operative difficulty
Population‐based cohort study of outcomes following cholecystectomy for benign gallbladder diseases
- Author
- Aawsaj Y
- Abayomi M
- Acharya V
- Aggarwal SK
- Ahmad A
- Ahmed I
- Ahmed J
- Ahmed J
- Ahmed T
- Ainley P
- Akhtar M
- Al Amari K
- Al-Abed YA
- Al-Akash M
- Al-Bahrani AZ
- Al-Khyatt W
- Al-Muhktar A
- Al-Taan O
- Alagaratnam S
- Alam I
- Alberts J
- Alderson D
- Aldridge RC
- Aleksandrov D
- Ali A
- Ali H
- Ali S
- Amin K
- Andrew DR
- Appleton S
- Arhi C
- Aroori S
- Aryal K
- Asad M
- Aseem R
- Asprou FM
- Awan A
- Ayaani S
- Babu BI
- Bajwa DS
- Bajwa FM
- Baker AL
- Balfe P
- Ball WR
- Ballance L
- Banwell V
- Barnes J
- Barrie J
- Bartlett F
- Basheer M
- Bashir G
- Basra M
- Basu S
- Basynat P
- Batt J
- Bausbacher H
- Bawa S
- Beasley WD
- Belding R
- Bellini MI
- Bennett SP
- Bhandari S
- Bhattacharya V
- Blane C
- Blazeby JM
- Boal M
- Boddy A
- Boland M
- Bond-Smith G
- Booth MI
- Borowski DW
- Bowen L
- Boyce KM
- Boyd AT
- Bradley D
- Bradley N
- Brennan S
- Brett D
- Broadhurst J
- Brooke E
- Brown TH
- Bryant A
- Buchan J
- Bullen N
- Bunnell C
- Bunting DM
- Burke P
- Byrne JP
- Byrnes CK
- Campbell W
- Carney K
- Carney K
- Carroll P
- Carter CR
- Carter NC
- Carty N
- Cassidy JT
- Chambers A
- Chambers A
- Chambers A
- Chan WM
- Chang J
- Chauhan N
- Cheung M
- Chishti IA
- Chitre V
- Choy A
- Cieplucha K
- Clements JM
- Coats M
- Cockbain AJ
- Coe PO
- Collaborative WMR
- Connelly M
- Cooke F
- Courtney MJ
- Cowley JB
- Cross KS
- Cuming T
- Cunha P
- D'Costa C
- Dalgaty F
- Dar F
- Date R
- Dave RV
- Davey P
- Davies J
- Dawson S
- De Marchi JA
- de Siqueira J
- Deguara J
- Delisle TG
- Dennison AR
- Derbyshire L
- Devoto L
- Dhillon A
- Diamond T
- Dickson-Lowe R
- Digney R
- Dindyal S
- Dobbins B
- Doe M
- Dorrian E
- Doulias T
- Downing J
- Downing J
- Drake B
- Driscoll PJ
- Duke D
- Durkin D
- Dwerryhouse SJ
- Ebdewi H
- Ebied H
- Eisawi A
- El-Dhuwaib Y
- El-Hasani SS
- Elkheir N
- Elmasry M
- Elsayed M
- Elshaer M
- Emeshi S
- Farag SF
- Farooq A
- Farouk M
- Fasih T
- Fawole AS
- Fenwick S
- Ferguson G
- Ferris P
- Finch D
- Finch JG
- Finlay I
- Fleming K
- Fletcher T
- Fordham IJ
- Forouzanfar A
- Forrest CR
- Forster L
- Fothergill L
- Frame RJ
- Francombe J
- Frank L
- Fusai G
- Galanopoulos G
- Gallagher PV
- Garcea G
- Gardner-Thorpe J
- Geoghegan JG
- Geogloma I
- Gerakopoulos S
- Ghareeb E
- Ghazanfar MA
- Gibson S
- Giles M
- Giovinazzo F
- Goh YL
- Gopalswamy S
- Goscimski A
- Gossage JA
- Gough M
- Gould L
- Gould L
- Grant AJ
- Gravante G
- Griffiths EA
- Grp CS
- Gull S
- Gunasekera RT
- Gurung K
- Guthrie GJK
- Hafiz S
- Halkias C
- Hall C
- Hamady Z
- Hamdan A
- Hamdan MF
- Hamilton E
- Hancorn K
- Haque M
- Hardy TJ
- Hargreaves A
- Harilingam ACM
- Harris A
- Harrison E
- Hawkins H
- Heath J
- Hebbar M
- Henderson LT
- Henley N
- Heshaishi M
- Hewes J
- Hewes JC
- Heywood N
- Higgs SM
- Hill ADK
- Hill ADK
- Hindley C
- Hirst NA
- Hisham E
- Ho W-M
- Hoban JR
- Hodgkins KA
- Holroyd DJ
- Hooks G
- Hopwood B
- Hornby ST
- Hornsby J
- Hosie KB
- Hossack MR
- Hossain T
- Hoti E
- Hou D
- Hrycaiczuk A
- Hughes M
- Hunter DI
- Hussain A
- Hussain A
- Hussain AA
- Hussain N
- Iftikhar SY
- Iqbal LGN
- Iskandar E
- Issa E
- Ivanovski I
- Jackson A
- Jackson C
- Jafferbhoy SF
- Jambulingam P
- Jamdar S
- Jamel S
- Janeczko A
- Jaunoo S
- Jayanthi NVG
- Jelley C
- Jennings NA
- Joel A
- Johnpulle MA
- Johnston D
- Johnstone M
- Johnstone M
- Joji N
- Jones C
- Jones E
- Jones GH
- Jones MA
- Jones MJ
- Jones RP
- Jones SM
- Kadhim A
- Kadirkamanathan S
- Kallaway C
- Kanakala V
- Kanavati O
- Kansal N
- Kaptanis S
- Karavadra B
- Karim L
- Karunakaran P
- Kaur P
- Kausar A
- Kelly ME
- Kendal C
- Kennedy D
- Kenny R
- Keogh K
- Khalil AM
- Khan A
- Khan MA
- Khan MAS
- Khan RB
- Khan S
- Khan S
- Khawaja A
- Khawaja Z
- Khogali E
- Kimble A
- Kinghorn A
- Kirkham AJ
- Knight B
- Knight K
- Kourkulos M
- Krysztopik R
- Kumar P
- Kynaston J
- Kyriakidis D
- Lalla K
- Lammy S
- Lane R
- Larkin D
- Law J
- Lawther R
- Lazim T
- Lee K
- Lee M
- Leeder P
- Lennon H
- Lewis M
- Lim HCC
- Lim PJ
- Lindsay D
- Lloyd D
- Lo C
- Lodhia J
- Longbotham DA
- Loughlin P
- Lovett B
- Luhmann A
- Luther A
- Lyons EM
- Macano CAW
- MacArtney M
- Macdonald A
- Madanipour S
- Madbak K
- Madurska M
- Magee CJ
- Maguire D
- Maharaj G
- Majeed A
- Malcolm C
- Malde D
- Malik NS
- Mallik M
- Mansour S
- Manu M
- Manzelli A
- Marriott P
- Martin J
- Martin S
- Martin ST
- Marudanayagam R
- Mason D
- Mathur P
- Mawhinney A
- Mbuvi J
- McAree B
- McCain S
- McCallum IJD
- McClarey A
- McCune K
- McDermott F
- McEntee GP
- McGlone ER
- McGuigan A
- McIlmunn C
- Mckay D
- McKenzie S
- McNair AGK
- Mealy K
- Menzies D
- Mercer SJ
- Milburn J
- Mirza AK
- Mirza D
- Miu V
- Mockford KA
- Mohamed S
- Mohan HM
- Mok J
- Monk D
- Morcous P
- Morrison TEM
- Mothe BS
- Mowbray N
- Mozolowski KL
- Mukherjee D
- Murphy JO
- Murtaza G
- Nally DM
- Napetti S
- Nassar AH
- Naumann D
- Nedujchelyn Y
- Needham PJ
- Newton K
- Newton RC
- Ngu WS
- Nicholson GA
- Nicholson J
- Nicholson JA
- Nicol L
- Nicolay CR
- Nieto T
- Nijjar RS
- Nilsen-Nunn A
- Nilsson F
- Noble F
- Nofal E
- Noor N
- Nunes Q
- O'Dwyer P
- O'Neill MA
- O'Neill S
- O'Reilly DA
- O'Shea KM
- O'Sullivan AW
- Obeidallah MR
- Ogedegbe A
- Old OJ
- Orchard P
- Orizu MN
- Packer JR
- Padwick R
- Pannu A
- Panteleimonitis S
- Parappally CP
- Parmar J
- Pasquali S
- Patel A
- Patel K
- Patel S
- Pati P
- Pearce B
- Pearson KL
- Peirce C
- Pellen M
- Peter MB
- Peterson M
- Pezzuto R
- Photi E
- Phull M
- Pinho-Gomes AC
- Pollock S
- Popplewell M
- Pore N
- Porter J
- Prasad AR
- Prasad R
- Preston SR
- Preziosi G
- Prince S
- Psica A
- Puig S
- Puntis DJ
- Puri Y
- Qandeel H
- Rabie M
- Radwan R
- Rae DM
- Rahman S
- Rajaganeshan R
- Rajendran I
- Ramage MI
- Rao STV
- Rate AJ
- Raza S
- Read E
- Reddy M
- Reece-Bolton O
- Reed J
- Reid A
- Rengifo C
- Rhys T
- Richards CH
- Riera M
- Ritchie J
- Robb W
- Roberts GP
- Robinson S
- Robinson S
- Robinson SJ
- Rodriguez D
- Rodriguez DU
- Roebuck A
- Rogers PN
- Rolph RC
- Roy S
- Rutherford CL
- Sadat MM
- Sakai N
- Sampat K
- Samuel N
- Sarmah PB
- Sarvananthan K
- Sarveswaran J
- Satheesan S
- Saunders M
- Sayegh M
- Segaran A
- Sekhar H
- Sen G
- Seymour K
- Shabo W
- Shah N
- Shah R
- Shahin Y
- Sheel ARG
- Shenoy H
- Shetty V
- Shier D
- Shingler GM
- Shiwani MH
- Shrestha AK
- Siddiqi N
- Siddiqui MN
- Siddiqui Z
- Sillo TO
- Silva M
- Simpson DJ
- Singh S
- Singh-Ranger D
- Sinha S
- Skelly BL
- Slavin JP
- Slawinski C
- Sloane J
- Smith SR
- Smith SR
- Spearman J
- Spence G
- Spreadborough P
- Spreadborough P
- Starmer BZ
- Stevenson TEJ
- Stewart DJ
- Stirland E
- Subramanium D
- Sufi PA
- Sukha A
- Sutcliffe R
- Suttie S
- Sutton CMLR
- Szentpali K
- Tang C-B
- Tanner N
- Tate S
- Tayeh S
- Taylor C
- Taylor GW
- Teasdale RL
- Templeton A
- Terrace J
- Thakkar R
- Thomas G
- Thompson RLE
- Tilston MP
- Toh SKC
- Tolofari S
- Tomlinson MA
- Trevatt AEJ
- Trotter M
- Tsang A
- Tsavellas G
- Tuck L
- Turner P
- Tutton MG
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- Ullah MF
- Upchurch EA
- Urbonas T
- Varghase J
- Vass DG
- Vaughan EM
- Vijay V
- Vijayan D
- Vijayanand D
- Villatoro E
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- Wilkinson MD
- Williams SV
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- Willson PD
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- Wilson TR
- Winter DC
- Winter H
- Wood CPJ
- Wood P
- Wood S
- Woodman T
- Yahya S
- Yao C
- Yeldham G
- Yoganathan T
- Youssef H
- Zafar S
- Zafrani Z
- Zarsadias P
- Zeeshan S
- Zhang C
- Ziprin P
- Publication venue
- 'Wiley'
- Publication date
- 01/11/2016
- Field of study
Background The aim was to describe the management of benign gallbladder disease and identify characteristics associated with all‐cause 30‐day readmissions and complications in a prospective population‐based cohort. Methods Data were collected on consecutive patients undergoing cholecystectomy in acute UK and Irish hospitals between 1 March and 1 May 2014. Potential explanatory variables influencing all‐cause 30‐day readmissions and complications were analysed by means of multilevel, multivariable logistic regression modelling using a two‐level hierarchical structure with patients (level 1) nested within hospitals (level 2). Results Data were collected on 8909 patients undergoing cholecystectomy from 167 hospitals. Some 1451 cholecystectomies (16·3 per cent) were performed as an emergency, 4165 (46·8 per cent) as elective operations, and 3293 patients (37·0 per cent) had had at least one previous emergency admission, but had surgery on a delayed basis. The readmission and complication rates at 30 days were 7·1 per cent (633 of 8909) and 10·8 per cent (962 of 8909) respectively. Both readmissions and complications were independently associated with increasing ASA fitness grade, duration of surgery, and increasing numbers of emergency admissions with gallbladder disease before cholecystectomy. No identifiable hospital characteristics were linked to readmissions and complications. Conclusion Readmissions and complications following cholecystectomy are common and associated with patient and disease characteristics
Trends in inpatient antiparkinson drug use in the USA, 2001–2012
- Author
- A Antonini
- A Arasalingam
- A Wright Willis
- AH Schapira
- Allison W. Willis
- AW Willis
- AW Willis
- AW Willis
- C Renoux
- C Zadikoff
- D Weintraub
- Dafna E. Kohen
- Daniel Krewski
- Donald Mattison
- Dylan P. Thibault
- G Trifiro
- IA Halkias
- J Jankovic
- J Jankovic
- James A. G. Crispo
- JM Miyasaki
- K Seppi
- L Brusa
- L Brusa
- L Parkkinen
- Lise M. Bjerre
- M Braga
- M Steiger
- Matthew Emons
- MB Callesen
- MM Mokhles
- MM Rosa
- MT Herrero
- N Dahodwala
- NJ Diederich
- NJ Weerkamp
- O Leoni
- O Suchowersky
- PH Hsieh
- R Fuente-Fernandez de la
- S Nakaoka
- S Perez-Lloret
- SA Factor
- SA Hollingworth
- Santiago Perez-Lloret
- SH Fox
- SK Eeden Van Den
- TB VanItallie
- TJ Moore
- Yannick Fortin
- YJ Wei
- Z Pirtosek
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Evaluation of appendicitis risk prediction models in adults with suspected appendicitis
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- Abbas Sh
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- Patel Mm
- Patel N
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- Peiris Gb
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- Pertile D
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- Photiou D
- Pierre R
- Pietrabissa A
- Pigem A
- Pila U
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- Pineño-Flores C
- Pinillos-Somalo A
- Pinkney Td
- Pinkney Td
- Pinkney Td
- Pinna E
- Pino-Perez O
- Pirari Pf
- Pisanu A
- Piu F
- Planellas P
- Plua-Muniz Kt
- Poacher A
- Podda F
- Podda M
- Podda M
- Podda M
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- Pollard H
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- Poudevigne M
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- Prideaux A
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- Provenza G
- Puerta E
- Pulighe F
- Pullabatla-Venkata Up
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- Rabie Ma
- Rabie Mr
- Radwan Rw
- Radwan Rw
- Rahim A
- Rahman M
- Rahmani Ls
- Rajagopal S
- Rajaram R
- Rajaretnam N
- Rajjoub Y
- Rallage H
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- Ramirez-Redondo Aa
- Ramos Xh
- Ramos-Bernado Mi
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- Ranathunga S
- Rangarajan K
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- Rao V
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- Rashid M
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- Ravindran R
- Raymond M
- Raza Ss
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- Redondo E
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- Regina G
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- Rezacova M
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- Roncero Ls
- Ronda Rn
- Roomi S
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- Roscio F
- Rossi C
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- Roth N
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- Roxburgh C
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- Rubbini M
- Rudland I
- Ruffolo C
- Rufo E
- Ruggiu Gv
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- Ruiz-Marín M
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- Rutherford Dg
- Ruzvidzo F
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- Saba A
- Sabia D
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- Salamone G
- Salamone G
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- Salandini Mc
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- Salim S
- Salva Ab
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- Sancho-Muriel J
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- Santurro L
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- Sarmah P
- Sarmah P
- Sarmah P
- Sarveswaran J
- Sasia D
- Sasia D
- Saunders S
- Savill A
- Savino G
- Savino G
- Savioli F
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- Scabini S
- Scabini S
- Scandroglio Is
- Scanlon K
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- Scialandrone G
- Scricciolo M
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- Segura-Sampedro Jj
- Sena G
- Sena-Ruiz F
- Seneviratne N
- Sepe C
- Serventi F
- Serventi F
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- Setshwaelo T
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- Sgrò A
- Sgrò A
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- Shah Sm
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- Shakoor Z
- Shanmuganathan V
- Shanmugarajah K
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- Sharma A
- Sharma P
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- Sharp Ol
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- Shetty Vd
- Shingler G
- Shiwani Mh
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- Siaw O
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- Siddiqui Mn
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- Siggens Kl
- Sihra N
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- Smallcombe N
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- Smart Cj
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- Smoker H
- Soares A. S.
- Soares As
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- Soh B
- Solaini L
- Solar-García L
- Soliani P
- Solinas L
- Sooriyamoorthy T
- Soria-Aledo V
- Soria-Aledo V
- Soriano Jt
- Sorrentino L
- Sousa Hs
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- Sparta C
- Spaziani A
- Speake D
- Speake D
- Springate El
- Sreedharan L
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- Staderini F
- Stecca T
- Stella M
- Stephens Gf
- Stephens Gf
- Stevenson R
- Stewart Dj
- Stoica I
- Storey R
- Stoyanov Ti
- Strachan E
- Strange Ja
- Stubbs Bm
- Stupalkowska W
- Stupalkowska W
- Suarez-Cabrera A
- Suero Ca
- Sultana A
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- Sunter H
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- Swords C
- Symons N
- Szentpali K
- Szucs A
- Szucs A
- Sánchez-Cifuentes A
- Sánchez-Fuentes Mn
- Sánchez-Rubio M
- Tabain V
- Taglietti L
- Tague Le
- Tahir W
- Tailor K
- Tallon-Aguilar L
- Tallon-Aguilar L
- Tamayo-López Mj
- Tamborska A
- Tamini N
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- Tinsley Bj
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- Tomasoni M
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- Toomey D
- Toomey Db
- Torkington J
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- Torrado Aa
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- Torrance A
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- Townsend Dc
- Tozer Pj
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- Tudyka V
- Tudyka V
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- Tyler R
- Ugarte-Sierra B
- Vacca A
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- Vakis S
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- Vallejo-Bernad C
- Vallve-Bernal M
- Van Boxel Gi
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- Vannucchi A
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- Vaughan Em
- Vaughan Em
- Vazquez-Fernandez Ap
- Vega L
- Velchuru Vr
- Velho R
- Venkata Up
- Venkatasubramaniam Ak
- Venn Ml
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- Venugopal R
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- Veres T
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- Vescio G
- Vettoretto N
- Vigorita V
- Vijay V
- Vila-Zarate C
- Villarejo-Campos P
- Vinnicombe Z
- Viscosi F
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- Viviani E
- Viñas Nl
- Vohra R
- Vohra R
- Vulcano I
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- Whittaker L
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- Wijesundera K
- Wilcox G
- Wilkin R
- Wilkin R
- Wilkin R
- Wilkin R
- Wilkin R. J. W.
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- Williams M
- Williams R
- Williams S
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- Woodward A
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- Yeung K
- Yeung K
- Yoganathan S
- Yoong S
- Youssef H
- Yow L
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- Zaborowski A
- Zadi Az
- Zalla T
- Zarka Za
- Zarka Za
- Zarog Ma
- Zelazek M
- Zerpa C
- Zhang Ay
- Zhou S
- Zorrilla L
- Zuin M
- Zurleni Tz
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2019
- Field of study
Background
Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis.
Methods
A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis).
Results
Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent).
Conclusion
Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified
The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism
- Author
- A Dekundy
- A Dekundy
- A Mura
- A Sánchez
- A Thomas
- AP Tsou
- C Ghelardini
- CA Frye
- CG Goetz
- Charles K. Meshul
- CP VanderMaelen
- CW Olanow
- D Frechilla
- DK Chan
- E Hajós-Korcsok
- Elizabeth G. Brudney
- EV Kuzhikandathil
- F Bibbiani
- F Mela
- FF Matos
- G Fabbrini
- G Giovanni Di
- G Holoubek
- G Levandis
- G Skuza
- GA McPherson
- GD Bartoszyk
- GR Gewirtz
- H Schoemaker
- H Ujike
- H Ujike
- H Ujike
- H Ujike
- IA Halkias
- IM Stanford
- J Zhang
- JB Feldstein
- JD Leander
- JG Nutt
- JJ Canales
- JL Taylor
- JP Yevich
- JR Lever
- JW Chang
- K Hashimoto
- K Kannari
- K Kannari
- K Okumura
- Katherine Foley
- KB Dupre
- KB Dupre
- KD Alex
- KL Eskow
- L Bardin
- L Chen
- L Matuszewich
- L Verhagen Metman
- L Verhagen-Metman
- LJ Bristow
- LJ Mignon
- M Abou-Gharbia
- M Abou-Gharbia
- M Ba
- M Bevilacqua
- M Bishnoi
- M Kleven
- M Lundblad
- M Lundblad
- M Mavridis
- M Tomiyama
- M Wood
- MA Bédard
- MA Cenci
- MA Paquette
- MD Kelland
- Melanie A. Paquette
- MH Yen
- MJ Müller
- MM Iravani
- MS Kleven
- MT Huber
- P Dotto Del
- P Romieu
- P Romieu
- P Romieu
- PJ Blanchet
- PM Callahan
- R Bhidayasiri
- R Perrone
- R Stefanski
- RE Solomon
- RM Eglen
- RM Frieboes
- RN Waterhouse
- RR Matsumoto
- RR Matsumoto
- RT Matthews
- S Ahlenius
- S Modell
- S. Paul Berger
- SA Vanecek
- SC Miller
- SJ Peroutka
- SL Patrick
- SM Papa
- SN Calderon
- Steven W. Johnson
- T Antonelli
- TS Rao
- V Bonifati
- WS Cobb
- Y Temel
- Z Xiang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Preoperative risk factors for conversion from laparoscopic to open cholecystectomy: a validated risk score derived from a prospective U.K. database of 8820 patients
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- Abayomi M
- Acharya V
- Aggarwal SK
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- Ahmed I
- Ahmed J
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- Al-Abed YA
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- Teasdale RL
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- Tilston MP
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- Zarsadias P
- Zeeshan S
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- Ziprin P
- Publication venue
- Elsevier B.V.
- Publication date
- 01/01/2016
- Field of study
Background Laparoscopic cholecystectomy is commonly performed, and several factors increase the risk of open conversion, prolonging operating time and hospital stay. Preoperative stratification would improve consent, scheduling and identify appropriate training cases. The aim of this study was to develop a validated risk score for conversion for use in clinical practice. Patients and methods Preoperative patient and disease-related variables were identified from a prospective cholecystectomy database (CholeS) of 8820 patients, divided into main and validation sets. Preoperative predictors of conversion were identified by multivariable binary logistic regression. A risk score was developed and validated using a forward stepwise approach. Results Some 297 procedures (3.4%) were converted. The risk score was derived from six significant predictors: age (p = 0.005), sex (p < 0.001), indication for surgery (p < 0.001), ASA (p < 0.001), thick-walled gallbladder (p = 0.040) and CBD diameter (p = 0.004). Testing the score on the validation set yielded an AUROC = 0.766 (p < 0.001), and a score >6 identified patients at high risk of conversion (7.1% vs. 1.2%). Conclusion This validated risk score allows preoperative identification of patients at six-fold increased risk of conversion to open cholecystectomy
Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
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- A'Court J
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- Abbadessa F
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- Publication venue
- 'BMJ'
- Publication date
- 01/01/2021
- Field of study
Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis. Setting Prospective, international, multicentre, observational cohort study. Participants Patients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative). Primary outcome 30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality. Results This study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787). Conclusions Patients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups. Trial registration number NCT0432364
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y
- Abadia M
- Abad‐Gurumeta A
- Abad‐Motos A
- Abassy J
- Abate E
- Abbasov A
- Abbott D
- Abbott Tom EF
- Abdalla M
- Abdeldayem H
- Abdelkabir M
- Abdelkader Salama I
- Abdelkarim M
- Abdelsamed A
- Abdulfattah F
- Abdulwahed E
- Abdur‐Rahman LO
- Abel MK
- Abelevich A
- Abiyere H
- Aboelkassem Ibrahim A
- Aboharp Hasan Z
- Abou Chaar MK
- Abreu da Silva A
- Abubakar A
- Abukhalaf SA
- Abukhalaf Sadi
- Acebes García F
- Achalandabaso Boira M
- Acher A
- Acosta Mérida MA
- Acrich E
- Adam Essa Adam ME
- Adamina M
- Adamina Michel
- Adamina Michel
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- Jimenez Toscano M
- Jimenez V
- Jiménez A
- Jobran F
- Jocson R
- Johnstone J
- Jones Conor S
- Jonescheit J
- Jonker Pascal
- Jordan P
- Jordan S
- Jouffret L
- Jover JM
- Jovine E
- JW Wilkin Richard
- Jácome F
- Jäger T
- Kaafarani H
- Kaafarani Haytham MA
- Kacem MJ
- Kakotkin V
- Kalayarasan R
- Kalfountzos C
- Kam da Silva Andrade A
- Kamal M
- Kamal N
- Kamalov A
- Kamarajah Sivesh K
- Kamarajah Sivesh K
- Kamburoğlu MB
- Kamel F
- Kamera BS
- Kamoka E
- Kamphues C
- Kanemitsu Y
- Kannummal Veetil S
- Kanthasamy S
- Kapoor S
- Kappenberger A
- Kara H
- Kara Y
- Karahasanoglu T
- Karaitianos IG
- Karamarkovic A
- Karandikar S
- Karim A
- Karimuddin A
- Karlović D
- Kashif M
- Kasivisvanathan Veeru
- Kassir R
- Katory M
- Kattakayam A
- Katusic Z
- Kaul S
- Kauppila JH
- Kauppila JH
- Kaushal M
- Kavanagh D
- Kaya T
- Kayyal MY
- Kazachenko E
- Keatley James M
- Kebabçı E
- Kecmanović D
- Keeler BD
- Keller Debby
- Keller Debby
- Kembuan G
- Kenic M
- Kennelly R
- Kent A
- Kerawala AA
- Khajuria A
- Khan A
- Khan AH
- Khan F
- Khan J
- Khan K
- Khan S
- Khan Tabassum
- Khatri Chetan
- Khaw Rachel A
- Khokhar MI
- Kiconco H
- Kilani AI
- Kilinc Tuncer G
- Killeen S
- Kim NJ
- Kirmizi Y
- Kjaer DW
- Klaristenfeld D
- Klatte Tobias
- Kleeff J
- Kler A
- Klimopoulos S
- Kloppers C
- Kmezić S
- Knezevic D
- Knight Andrew
- Knights E
- Knowles C
- Knowles J
- Kocatas A
- Koh A
- Kokkinos G
- Kokobelyan AK
- Kokoropoulos P
- Koleva Radica M
- Kolias Angelos
- Kolias Angelos
- Kolla C
- Kollengode VV
- Kolli VS
- Konney Thomas
- Konstadoulakis M
- Konstantinou C
- Konsten J
- Kontovounisios C
- Kornblith LZ
- Kottayasamy Seenivasagam R
- Koukoulis G
- Kourdouli A
- Kovacevic B
- Kowalewski P
- Krarup P
- Krdzic I
- Kredan A
- Kretzmer L
- Krishnan E
- Kristensen HØ
- Krivokapic Z
- Kroon HM
- Kruijff Schelto
- Kršul D
- Kubiliute E
- Kubyshkin V
- Kucuk GO
- Kudchadkar S
- Kuiper S
- Kulkarni N
- Kulkarni R
- Kulle CB
- Kumar A
- Kumar L
- Kumar S
- Kumar V
- Kutkevičius J
- Kuttanchettiyar KG
- Kwan‐Feinberg R
- Kwiatkowski A
- Kyriacou H
- Kälviäinen H
- Königsrainer A
- Küçük IF
- La Regina D
- La Torre F
- Labib PL
- Lacy AM
- Ladd MR
- Laface L
- Laforest A
- Laharwal A
- Lakkis Z
- Lala AK
- Lalou L
- Lamb Benjamin
- Landaluce‐olavarria A
- Lapolla P
- Laporte G
- Larentzakis A
- Larkin J
- Laskar N
- Lasses Martínez B
- Latinčić S
- Lauretta A
- Lauscher J
- Lavy R
- Law J
- Lawani Ismail
- Lawday S
- Lawday Samuel
- Lawday Samuel
- Layton Georgia R
- Le Roy B
- Lecolle K
- Lederhuber Hans
- Lederhuber Hans
- Ledesma FS
- Lee M
- Lee N
- Leede E
- Lenzi E
- Leon R
- Leung Elaine YL
- Leventoglu Sezai
- Leventoglu Sezai
- Lewis‐Lloyd C
- Li Elizabeth
- Li Elizabeth
- Li M
- Li Z
- Liakakos T
- Liao CCL
- Lieske B
- Lim M
- Lim RZM
- Lima Buarque I
- Lima da Cruz L
- Lima da Silva C
- Lima MJ
- Linari C
- Lippa Laura
- Lira dos Santos Leite A
- Litta F
- Litvin A
- Litvin Andrey
- Litvina Y
- Liu J
- Liu T
- Lizzi V
- Locatelli A
- Loch FN
- Loehrer A
- Loehrer Andrew
- Loncar Z
- Long C
- Longhi M
- Longhini A
- Longstaff L
- Lopes L
- Lopez Abad A
- Lora‐Cumplido P
- Lorena Maria Aguilera
- Lorenzon L
- Losada M
- Lott N
- Loubani M
- Loutzidou L
- Lowery A
- Lozano Lominchar P
- Lucchini SM
- Luglio G
- Lule H
- Lun EWY
- Lunevicius R
- Lunghi EG
- Lynch N
- Lyons A
- Lázaro A
- López Antoñanzas L
- Löffler Markus W
- Löffler MW
- Löfgren N
- M. elghazaly S
- Maa Albared S
- Maccabe TA
- MacDonald L
- Machado D
- Machado N
- Macina S
- Madani Kia T
- Madani R
- Madonini M
- Maffioli A
- Magee C
- Maghrebi H
- Magowan D
- Mahajan A
- Mahendran V
- Mahmood M
- Mahmoud Ali F
- Mahvi D
- Maida P
- Maiga A
- Maimbo Mayaba
- Majbar AM
- Majkowska A
- Major P
- Major Piotr
- Majrashi S
- Majumdar KS
- Mak TWC
- Malapati H
- Malcolm FL
- Malgras B
- Malibary N
- Mall JW
- Maltinti G
- Manatakis DK
- Manfredelli S
- Manku B
- Mann Harvinder S
- Manrique E
- Manso I
- Manson J
- Mantoglu B
- Manu N
- Maqueda González R
- Marafante C
- Marano A
- Marchbank Adrian
- Marcos‐Santos P
- Marcus Hani J
- Mardare M
- Margalit A
- Mari G
- Marialva J
- Mariani NM
- Marie‐Macron L
- Marinello P
- Marino Cosentino L
- Marino M
- Marino MV
- Markaryan D
- Markovic I
- Markovic V
- Marques R
- Marques T
- Marqueta De Salas M
- Marra AA
- Marra E
- Marreiro A
- Marson Ella J
- Marte G
- Martel A
- Martin E
- Martin E
- Martin Janet
- Martin ST
- Martinek L
- Martinez German A
- Martins dos Santos G
- Martins Jordão D
- Martins A
- Martins D
- Martins R
- Martin‐Perez B
- Martin‐Perez E
- Martín Anoro LF
- Martín L
- Martínez Chicote C
- Martínez‐Hurtado E
- Martínez‐Pinedo C
- Martínez‐Pérez P
- Martín‐Arévalo J
- Marx W
- Marzi F
- Marçal A
- Marín H
- Masciandaro A
- Mashat A
- Mashbari Hassan N
- Massey LH
- Massie E
- Massobrio A
- Mastoridis S
- Math S
- Mathew S
- Matić S
- Matos Costa P
- Matute M
- Maté Mate P
- Matías‐García B
- Maw A
- Mazingi Dennis
- Mazzotta E
- Mazzotti F
- McAleer J
- McAree B
- McCanny A
- Mccluney S
- Mccormick P
- McDermott FD
- McElhinney K
- McEwen R
- McGivern K
- McGrath John S
- McIlmunn C
- McIntosh S
- McIntyre J
- McKay Siobhan
- Mckay Siobhan C
- McKevitt K
- McLean Kenneth A
- McNaught C
- McNeill Alan
- McNicol F
- MdRazali. I null
- Mehigan BJ
- Mehraj A
- Meima‐van Praag EM
- Mekhael M
- Melchor‐Ruan J
- Melenhorst J
- Melhem S
- Memon AS
- Memos N
- Mendes F
- Mendes JR
- Mendoza‐Moreno F
- Meneghini S
- Mercado MÁ
- Merdrignac A
- Merh R
- Meriç S
- Messner F
- Metallidis Symeon
- Metwalli M
- Metzger J
- Michalopoulos N
- Michalski C
- Michel M
- Micic D
- Migliore M
- Mignot G
- Miguel T
- Mihanovic J
- Mihmanli M
- Miladinov M
- Milanović M
- Milic LJ
- Mills Emily C
- Mills SJ
- Milne K
- Minaya Bravo AM
- Minaya‐Bravo Ana
- Minaya‐Bravo Ana
- Minaya‐Bravo Ana
- Mingoli A
- Minicozzi A
- Minto G
- Mir I
- Mirabella A
- Miranda P
- Mirica RM
- Mirnezami R
- Mishra N
- Mishra S
- Mishra T
- Misra S
- Mitchell D
- Mitchell S
- Mithany R
- Mitra JK
- Mitrofan C
- Mittal R
- Mittal Rohin
- Miu V
- Mochet S
- Modolo Maria Marta
- Modolo Maria Marta
- Moftah M
- Moggia E
- Mohamed Sidek AS
- Mohammad Z
- Mohammed MM
- MohammedJibreel M
- Mohan H
- Mohan Helen M
- Mohan Helen M
- Mohd Azman ZA
- Mohd Yunus MF
- Mohsine R
- Mongelli F
- Montauban P
- Montelatici M
- Monteleone M
- Montella MT
- Montori G
- Montuori M
- Moore Rachel
- Moorthy M
- Morais H
- Moras L
- Mora‐Guzmán I
- Morelli L
- Moretto G
- Morgan R
- Moritani K
- Moro‐Valdezate D
- Morris A
- Morsi A
- Mosley F
- Moss J
- Moszkowicz David
- Moug S
- Moug Susan
- Moug Susan
- Moura F
- Mourad M
- Mshelbwala P
- Msherghi A
- Mudawi I
- Muduly D
- Muguerza JM
- Muiesan P
- Mukherjee S
- Muller B
- Mulligan CS
- Mungo S
- Muratore A
- Murawa D
- Murgese A
- Murphy C
- Musetti S
- Mustafa A
- Mutter D
- Muzamil J
- Muñoz Camarena JM
- Muñoz‐Atienza V
- Muñoz‐Bellvis L
- Naar L
- Nacif L
- Nafees Ahmed R
- Nageh MA
- Nahm C
- Najarian M
- Nally D
- Namazov İ
- Nankivell Paul
- Narahari Krishna
- Nassa H
- Nassif M
- Natale J
- Naumann D
- Navaratne L
- Nazir S
- Neary P
- Neary PM
- Neely D
- Negoi I
- Negoi Ionut
- Negoita VM
- Nel D
- Nelli T
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Neri J
- Nespoli LC
- Nessim C
- Neville Iuri
- Newman S
- Newman T
- Newton C
- Newton K
- Ng HJ
- Ng Joe
- Ng S
- Ng V
- Ng V
- Ngo CW
- Ng‐Kamstra Joshua S
- Nicolás‐López T
- Nikaj H
- Nikolaou S
- Nikolic S
- Niquen Milagros
- Nisar P
- Nitschke C
- Nogueira O
- Nogueiro J
- Nogués A
- Noiret B
- Nolan GJ
- Norcini C
- Nordberg M
- Notte F
- Nouh T
- Novello S
- Novikova A
- Nowak K
- Ntirenganya Faustin
- Nugent E
- Nunes Coelho M
- Nunes R
- Nunez‐Garcia B
- Nunoo‐Mensah JW
- Nuñez Del Barrio H
- Nwabuoku SE
- Núñez J
- Obeidat K
- Ocaña J
- Ochagavía S
- Oguttu B
- Okafor B
- Okunlola A
- Olaogun J
- Olasehinde O
- Oldfield F
- Oliva Mompean F
- Oliveira A
- Olivier J
- Olivieri M
- Olivos Maricarmen
- Olori S
- Olson KA
- Olute A
- Omar W
- Omeroglu S
- Ong SL
- Onos L
- Oosterlinck W
- Oosterling S
- Opocher E
- Ortega Vázquez I
- Ortiz de Solórzano Aurusa FJ
- Ortiz López D
- Osagie O
- Oseira A
- Osman N
- Osorio Ramos A
- Otero A
- Otoniel LR
- Oussama Kacimi
- Outani Oumaima
- Ovejero Merino E
- Owen H
- Owens P
- Oyende O
- Ozben V
- Ozcelık MF
- Ozgediz D
- Ozmen BB
- O’Brien H
- O’Brien S
- O’Donnell S
- O’Malley S
- O’Riordan J
- O’Shea M
- P Delrio
- Pacheco Sánchez D
- Padilla‐Valverde D
- Padmore G
- Pagano G
- Pajan H
- Palagi S
- Palma P
- Palmeri M
- Panahi P
- Pandey D
- Paniagua García Señorans M
- Papaconstantinou I
- Papadopoulos V
- Papagni V
- Papatheodorou P
- Paquette N
- Parasyris S
- Pareek P
- Pareja Rene
- Parello A
- Parente A
- Parini S
- Parise P
- Park J
- Parkin E
- Parkins K
- Parlanti D
- Parmar C
- Parra Baños PA
- Parray FQ
- Parreira R
- Parreño‐Sacdalan Marie Dione
- Parreño‐Sacdalan Marie Dione
- Parseliunas A
- Parwaiz I
- Pasini F
- Paspaliari D
- Pata Francesco
- Pata Francesco
- Pata Francesco
- Patel Akshay
- Patel K
- Patel M
- Patel P
- Patil S
- Patrone R
- Patrício B
- Pattyn P
- Pattyn P
- Pavlov M
- Pedrazzani C
- Pedro J
- Pedro V
- Peirce C
- Pejnovic L
- Pejovic I
- Pellegrino L
- Pellino G
- Pellino Gianluca
- Peluso C
- Penumadu P
- Pera R
- Peralta Ferreira M
- Pereca J
- Pereira Rodrigues A
- Pereira A
- Pereira C
- Pereira I
- Pereira R
- Perez Gonzalez M
- Perez D
- Pergolini I
- Perivoliotis K
- Peros G
- Perotto LO
- Perra T
- Perrone G
- Persad A
- Persiani R
- Pertile D
- Peteja M
- Petrillo A
- Peyroteo M
- Pezzuto AP
- Peña Ros E
- Peña Soria MJ
- Pham H
- Phan D
- Phang PT
- Phillips E
- Picardo AL
- Picciariello A
- Picciochi Maria
- Pickett L
- Picón Rodríguez R
- Pieniowski E
- Piessen G
- Pina S
- Pinilla Morales RE
- Pinkney Thomas D
- Pinotti E
- Pinto J
- Pipara A
- Piper Rory J
- Pipitone Federico NS
- Pirozzolo G
- Pirzada A
- Pisani Ceretti A
- Pisanu A
- Pius Ogolekwu I
- Pla‐Marti V
- Pockney P
- Pockney Peter
- Pockney Peter
- Pockney Peter
- Podda M
- Poeze M
- Poggioli G
- Police A
- Polydorou A
- Pol‐Fachin L
- Ponchietti L
- Popoola AA
- Porcu A
- Portinari M
- Posadas‐Trujillo OE
- Posma‐Bouman L
- Potter R
- Pourcher G
- Powell S
- Pozotou I
- Praetorius C
- Pramesh CS
- Prando D
- Presl J
- Price C
- Price Stephen J
- Prieto Calvo M
- Prieto Nieto MI
- Pronk AJM
- Prosperi P
- Provozina A
- Pruvot FR
- Pujari R
- Pujol Cano N
- Pérez Sánchez MA
- Pérez‐Saborido B
- Qadan M
- Qasem A
- Qatora MS
- Quante M
- Quintana Martinic M
- Quiroga‐Valcárcel A
- Qureshi Ahmad
- Qureshi AU
- Raby‐Smith W
- Radenkovic Dejan
- Raggio E
- Rai L
- Rajan S
- Rajaretnam N
- Rakvin I
- Ramachandran A
- Ramalho de Almeida F
- Ramamoorthy R
- Ramasamy S
- Ramcharan S
- Ramesh P
- Ramirez Faraco M
- Ramirez Romero P
- Ramos Bonilla A
- Ramos D
- Ramos‐De la Medina Antonio
- Ramos‐Martín P
- Ramwell A
- Rao S
- Rapaport S
- Rashid A
- Rashid MM
- Rasoaherinomenjanahary F
- Rattizzato S
- Ratto C
- Raval M
- Ravindrakumar S
- Ravindran S
- Rayamajhi S
- Raymond T
- Razafindrahita JB
- Recordare A
- Reddy P
- Redfern J
- Refky B
- Rega D
- Rega D
- Regina de Sampaio L
- Reilly J
- Reim D
- Reinhard T
- Revez T
- Rey Ferro M
- Rey Valcarcel C
- Reynolds IS
- Ribeiro A
- Ribeiro CG
- Ribeiro R
- Ribolla M
- Rice D
- Richards S
- Richards T
- Richards Toby
- Riddell A
- Ridgway PF
- Righini E
- Riley C
- Rimonda R
- Ringressi MN
- Ripollés‐Melchor J
- Riquoir Altamirano C
- Risaliti M
- Riva C
- Rivas R
- Rivera Carlos Jose Perez
- Rivera‐Alonso D
- Rizk M
- Rizzi A
- Roberts Keith
- Roberts Keith
- Robertson Faith
- Robinson A
- Roca Calvo MJ
- Rodrigo VSD
- Rodrigues K
- Rodriguez Artigas JM
- Rodriguez JL
- Rodríguez Gómez L
- Rodwell H
- Rogers LJ
- Rogers M
- Rojo López JA
- Roldón Golet M
- Romano M
- Romero Bañuelos E
- Romero de Diego A
- Ronellenfitsch U
- Rooney SM
- Rosa F
- Rose J
- Roslani AC
- Roslani April C
- Rosseau Gail
- Rossi S
- Roszkowski R
- Rottoli M
- Roux A
- Roxo V
- Roy Mahapatra S
- Royle T
- Rubio‐Perez I
- Ruivo A
- Ruiz Esquide M
- Ruiz Manzanera JJ
- Ruiz Soriano M
- Ruiz‐Escobar A
- Ruiz‐Marín M
- Russ J
- Russo IS
- Rutegård M
- Rutegård Martin
- Rutegård Martin
- Rutherford D
- Ruzgar NM
- Ruzzenente A
- Ryan M
- Ryan ÉJ
- Ryska O
- Río Lafuente FD
- S RRR
- Saad MM
- Saafan T
- Saavedra J
- Sabry A
- Saeed S
- Saez Carlin P
- Sagar J
- Sagnotta A
- Sahid Nik Amin
- Sahin I
- Sahnan K
- Saklani A
- Sakr A
- Saksena AR
- Salazar A
- Saleem A
- Saleem A
- Saleh M
- Salem H
- Salem H
- Salem M
- Salerno G
- Sales Mallafré R
- Salgado‐Nesme N
- Salim A
- Salimoğlu S
- Salindera S
- Sallam I
- Samadov E
- Samih A
- Samir Abdelaal A
- Samison LH
- Samkari A
- Sammarco G
- Sammour T
- Sampaio da Nóvoa Gomes Miguel II
- Sampaio Soares A
- Sampietro GM
- San Miguel C
- Sanchez Cabezudo Noguera F
- Sanchez Gonzalez J
- Sanchez Jimenez R
- Sanchez‐Casado AB
- Sanchez‐Pelaez D
- Sanchon L
- Sancho‐Muriel J
- Sanli AN
- Santanach C
- Santarrufina Martinez S
- Santero‐Ramirez MS
- Santos Bezerra T
- Santos Irène
- Santos PMDD
- Santos R
- Santos‐Sousa H
- Sanz Larrainzar A
- Sanz Ortega G
- Sanz‐López R
- Sapienza P
- Sapre D
- Saraiva P
- Sarantitis I
- Sarigul M
- Sarin A
- Sarjanoja E
- Sarma DR
- Sarpel U
- Sarre C
- Sartarelli L
- Sarveswaran J
- Sasapu K
- Sasia D
- Satoi Sohei
- Satoi Sohei
- Saudí S
- Sauvain M
- Sauvat F
- Saverio Salomone Di
- Saverio Salomone Di
- Savković N
- Sayyed R
- Sayyed Raza
- Scabini S
- Scalabre A
- Scanu AM
- Schache Andrew
- Schache Andrew G
- Schaller Karl
- Scheiwiller A
- Schiavo M
- Schiergens T
- Schineis C
- Schizas D
- Schlesinger N
- Schnitzbauer Andreas A
- Schwartz PB
- Scott L
- Scotton G
- Scrima O
- Sebai A
- Seebah K
- Seeliger B
- Seenivasagam Rajkumar Kottayasamy
- Seguin‐givelet A
- Segura‐Sampedro JJ
- Segura‐Sampedro Juan José
- Sehgal T
- Sehouli Jalid
- Seleim A
- Selmani J
- Semina E
- Sena G
- Senossi O
- Serevina OL
- Serralta de Colsa D
- Serrano González J
- Serrano‐Navidad M
- Sert İ
- Servadei Franco
- Seyi‐Olajide Justina O.
- Seymour Z
- Sganga G
- Sgrò A
- Shah J
- Shah S
- Shah ZA
- Shaikh I
- Shaikh S
- Shakoor Z
- Shanthakunalan K
- Sharabiany S
- Sharma Neil
- Sharma P
- Shaw Catherine A
- Shaw Richard
- Shaw Richard
- Sheel A
- Shehata S
- Shenit K
- Sheridan K
- Sherief M
- Sherif A
- Sherif Ahmed Elshawadfy
- Sherif G
- Shokuhi P
- Sholadoye TT
- Shortland T
- Shream S
- Shrestha A
- Shu Sebastian
- Shylasree TS
- Sian T
- Siaw‐Acheampong Kwabena
- Sibilla MG
- Siddiqui MT
- Sidiropoulos T
- Silva A
- Silva M
- Silva N
- Silva R
- Silveira Nunes I
- Silvestre D
- Simões JFF
- Singh AA
- Singh Jagdeep K
- Singh MP
- Singh R
- Singh S
- Singh S
- Sion M
- Skrovina M
- Smart Neil
- Smart Neil J
- Smith C
- Smith H
- Smith J
- Smith L
- Soh JY
- Sohrabi C
- Sokolov M
- Solari F
- Soldevila Verdeguer C
- Soliman H
- Soltan H
- Soreide Kjetil
- Soriano AI
- Soriero D
- Sorrentino L
- Sorribas Grifell M
- Sosa Duran EE
- Sosa‐Rodríguez MV
- Soto Montesinos C
- Souadka A
- Soulé Martínez CE
- Sousa Fernandes M
- Sousa R
- Sousa S
- Spagni G
- Spampinato MG
- Spanu A
- Spartalis E
- Spencer N
- Spiezio G
- Spinelli A
- Spinelli Antonino
- Spolini A
- Sreedharan L
- Srikumar B
- Sriram RK
- Srishankar S
- Sroczyński P
- St John S
- Stafford J
- Stavrinidou O
- Stebbing J
- Steele C
- Steidle C
- Steinke J
- Stevens K
- Stevenson J
- Stevic D
- Stewart Grant D
- Stewart Grant D
- Stewart KE
- Stockdale T
- Stoica B
- Strate T
- Stylianides N
- Stylianidis G
- Subhi MT
- Subocius A
- Subramaniam S
- Sud A
- Sund Malin
- Sundar Sudha
- Sundar Sudha
- Sundaram Venkatesan G
- Sundhu M
- Suszták N
- Sutherland A
- Swinson B
- Syed WAS
- Syllaios A
- Szatmary P
- Szubota I
- Sánchez del Pueblo C
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- Ćoza I
- Ławnicka A
- Žatecký J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Outcomes from elective colorectal cancer surgery during the SARS‐CoV‐2 pandemic
- Author
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- Wullschleger M
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- Yurttas C
- Zafar SN
- Zakaria AD
- Zakaria Z
- Zambon M
- Zanus G
- Zegarac M
- Zeli\u107 M
- Zengin AK
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zizzo M
- Zografos C
- Zorrilla Ort\ufazar J
- Zourntou S
- Zubaidi AM
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Aim
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic.
Method
This was an international cohort study of patients undergoing elective resection of colon or rectal cancer without preoperative suspicion of SARS-CoV-2. Centres entered data from their first recorded case of COVID-19 until 19 April 2020. The primary outcome was 30-day mortality. Secondary outcomes included anastomotic leak, postoperative SARS-CoV-2 and a comparison with prepandemic European Society of Coloproctology cohort data.
Results
From 2073 patients in 40 countries, 1.3% (27/2073) had a defunctioning stoma and 3.0% (63/2073) had an end stoma instead of an anastomosis only. Thirty-day mortality was 1.8% (38/2073), the incidence of postoperative SARS-CoV-2 was 3.8% (78/2073) and the anastomotic leak rate was 4.9% (86/1738). Mortality was lowest in patients without a leak or SARS-CoV-2 (14/1601, 0.9%) and highest in patients with both a leak and SARS-CoV-2 (5/13, 38.5%). Mortality was independently associated with anastomotic leak (adjusted odds ratio 6.01, 95% confidence interval 2.58–14.06), postoperative SARS-CoV-2 (16.90, 7.86–36.38), male sex (2.46, 1.01–5.93), age >70 years (2.87, 1.32–6.20) and advanced cancer stage (3.43, 1.16–10.21). Compared with prepandemic data, there were fewer anastomotic leaks (4.9% versus 7.7%) and an overall shorter length of stay (6 versus 7 days) but higher mortality (1.7% versus 1.1%).
Conclusion
Surgeons need to further mitigate against both SARS-CoV-2 and anastomotic leak when offering surgery during current and future COVID-19 waves based on patient, operative and organizational risks
Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott Tom EF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdel Al S
- Abdel Jalil R
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- Abellán M
- Aboelkassem Ibrahim A
- Abosamak NE
- Abou Chaar MK
- Abou Chaar Mohammad K.
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Za’nouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf Sadi
- Acebes García F
- Achalandabaso Boira M
- Acher A
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- Addae-Boateng E
- Ademuyiwa Adesoji O
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- on behalf of the COVIDSurg Collaborative
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- Vilatoba M
- Vilendecic Z
- Villalabeitia Ateca I
- Vimalachandran D
- Vimalachandran Dale
- Vimalchandran Dale
- Vinayagam R
- Violante T
- Visgauss J
- Viswambaram P
- Viswanath Y
- Vitali A
- Vitone L
- Vives RV
- Vo UG
- Vogel J
- Vollkommer T
- Von Papen M
- Vovola F
- Vucic N
- Vujanac V
- Wade R
- Wadham B
- Waheed S
- Wai K
- Wali A
- Walker C
- Walker D
- Walkes K
- Wallwork K
- Walton G
- Walton T
- Waqar SH
- Warburton H
- Ward D
- Ward S
- Waris Farooka M
- Warren O
- Warren Oliver J
- Waseem S
- Wasim T
- Watson D
- Watson LJ
- Watson N
- Weaver H
- Webber L
- Wedderburn Duane
- Weitz J
- Welsch T
- Wensley F
- Werner J
- West C
- West D
- Westwood E
- Whelan M
- Whelan P
- Whisker L
- Whitehall E
- Whitmore H
- Wilkin R
- Wilkin Richard JW
- Wilkins A
- Wilkins Alex
- Williams G
- Williams J
- Williams K
- Williams MA
- Williams T
- Williamson K
- Wilson M
- Wimberger P
- Wimmer A
- Winnand P
- Winter D
- Winter S
- Winter Stuart C
- Wolfer S
- Wong MPK
- Wong S
- Wong WJ
- Woodham A
- Woodun H
- Worku D
- Wright G
- Wright Naomi
- Wullschleger M
- Wustrack R
- Xenaki S
- Xu MJ
- Xyda SE
- Xynos E
- Yahaya AS
- Yang W
- Yassin N
- Ye G
- Yesantharao P
- Yetkin G
- Yeşilyurt D
- Yiallourou A
- Yıldırım A
- Yildiz A
- Ying Y
- Yip V
- Yordanov S
- Young R
- Yousof EA
- Youssef A
- Youssef M
- Yurttas C
- Yánez C
- Yüksel E
- Zacharoulis D
- Zafar SN
- Zakai D
- Zakaria AD
- Zakaria R
- Zakaria Z
- Zambelli MF
- Zambon M
- Zamora L
- Zamvar V
- Zani S
- Zanotti S
- Zanus G
- Zapardiel I
- Zarabini AG
- Zegarac M
- Zelić M
- Zeller N
- Zengin AK
- Zerbib P
- Zervas K
- Zese M
- Zhang H
- Zivanovic M
- Zivkovic M
- Zizzo M
- Zografos C
- Zonta S
- Zorrilla Ortúzar J
- Zourntou S
- Zouzoulas D
- Zubaidi A
- Zullo A
- Ângelo M
- Älgå A
- Çapoğlu R
- Çelebi F
- Çolak E
- Öfner D
- Öhlberger L
- Öğücü H
- Überrück L
- Ćoza I
- Šimko K
- Šćepanović V
- Žatecký J
- Камалов А
- Publication venue
- American Society of Clinical Oncology
- Publication date
- 01/01/2021
- Field of study