109 research outputs found
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A novel 3D imaging system for strawberry phenotyping
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Accurate and quantitative phenotypic data in plant breeding programmes is vital in breeding to assess the performance of genotypes and to make selections. Traditional strawberry phenotyping relies on the human eye to assess most external fruit quality attributes, which is time-consuming and subjective. 3D imaging is a promising high-throughput technique that allows multiple external fruit quality attributes to be measured simultaneously. A low cost multi-view stereo (MVS) imaging system was developed, which captured data from 360° around a target strawberry fruit. A 3D point cloud of the sample was derived and analysed with custom-developed software to estimate berry height, length, width, volume, calyx size, colour and achene number. Analysis of these traits in 100 fruits showed good concordance with manual assessment methods. This study demonstrates the feasibility of an MVS based 3D imaging system for the rapid and quantitative phenotyping of seven agronomically important external strawberry traits. With further improvement, this method could be applied in strawberry breeding programmes as a cost effective phenotyping technique
Identification of powdery mildew resistance QTL in strawberry (Fragaria × ananassa)
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Key Message: Powdery mildew resistance in two strawberry mapping populations is controlled by both stable and transient novel QTL of moderate effect. Some low transferability of QTL across wider germplasm was observed.
Abstract: The obligate biotrophic fungus Podosphaera aphanis is the causative agent of powdery mildew on cultivated strawberry (Fragaria × ananassa). Genotypes from two bi-parental mapping populations ‘Emily’ × ‘Fenella’ and ‘Redgaunt- let’ × ‘Hapil’ were phenotyped for powdery mildew disease severity in a series of field trials. Here, we report multiple QTL associated with resistance to powdery mildew, identified in ten phenotyping events conducted across different years and locations. Six QTL show a level of stable resistance across multiple phenotyping events; however, many other QTL were represented in a single phenotyping event and therefore must be considered transient. Subsequent screening of identified QTL across a validation set determined whether identified QTL remained closely linked to the associated resistance gene in the wider germplasm. Furthermore, a preliminary association analysis identified a novel conserved locus for further investigation. Our data suggest that resistance is highly complex and that multiple, primarily additive, sources of quantitative resistance to powdery mildew exist across strawberry germplasm. Utilisation of the reported markers in marker-assisted breeding or genomic selection would lead to improved powdery mildew-resistant strawberry cultivars, particularly where the studied parents, progeny and close pedigree material are included in breeding germplasm
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
- Author
- A Kong
- A Lomniczi
- A Murphy
- A Schröder
- AA D’Aloisio
- Aarno Palotie
- AB Migliano
- Adamo Pio D’adamo
- Aida K. Dieffenbach
- AL Dixon
- Albert Hofman
- Albert V. Smith
- Albertine J. Oldehinkel
- Alexander Teumer
- Alison M. Dunning
- Andrea D. Coviello
- Andrea Ganna
- Andres Metspalu
- Andrew C. Heath
- Andrew D. Johnson
- André G. Uitterlinden
- Angela Cox
- Anja Rudolph
- Anna M. Storniolo
- Anna Murray
- Anneli Pouta
- Annika Lindblom
- Antonietta Robino
- AP Abreu
- Arto Mannermaa
- AS Dimas
- AV Segrè
- B Kabakchiev
- B Zhang
- BE Stranger
- Behrooz Z. Alizadeh
- Ben A. Oostra
- Bernardo Bonanni
- Bjarke Feenstra
- BP Fairfax
- Bruce H. R. Wolffenbuttel
- C Colantuoni
- C Liu
- C-J Partsch
- Carl Blomqvist
- Catharina A. Hartman
- Cathy E. Elks
- CE Elks
- Christian Gieger
- Chunyan He
- CJ Willer
- Cornelia M. van Duijn
- CP Schaaf
- Craig E. Pennell
- D Mehta
- D Sasayama
- DA Cusanovich
- Daniel F. Gudbjartsson
- Daniel I. Chasman
- Daniel L. Koller
- David Couper
- David J. Hunter
- David Karasik
- David P. Strachan
- David Schlessinger
- Debbie Lawlor
- Deborah J. Thompson
- Diana L. Cousminer
- Dieter Flesch-Janys
- Diether Lambrechts
- Dirkje S. Postma
- DM Greenawalt
- Doris Stöckl
- Dorret I. Boomsma
- Douglas F. Easton
- Douglas P. Kiel
- E Grundberg
- E Grundberg
- E Grundberg
- Eco E. J. de Geus
- EE Schadt
- EK Speliotes
- EL Heinzen
- Eleonora Porcu
- Elisabeth Widen
- Elizabeth A. Streeten
- Ellen A. Nohr
- Ellen W. Demerath
- Emmi Tikkanen
- Enda M. Byrne
- Eric Boerwinkle
- Erik Ingelsson
- Erin K. Wagner
- Eva Albrecht
- Evelin Mihailov
- F Innocenti
- F Nagl
- F Zou
- Felix Day
- Femke Atsma
- Fergus J. Couch
- Fernando Rivadeneira
- Frank B. Hu
- Frank Geller
- GA Heap
- George Davey Smith
- George McMahon
- Georgia Chenevix-Trench
- Gerard Waeber
- Gisli Masson
- Gonneke Willemsen
- Graham G. Giles
- Grant W. Montgomery
- Gudmar Thorleifsson
- Gudny Eiriksdottir
- H Lango Allen
- H-J Westra
- Harold Snieder
- Heather A. Boyd
- Heli Nevanlinna
- Henri Wallaschofski
- Henrik Flyger
- Henry Völzke
- Hermann Brenner
- HHH Göring
- Hiltrud Brauch
- Hoda Anton-Culver
- IK Temple
- Ilja M. Nolte
- Immaculata De Vivo
- Irene L. Andrulis
- J Ding
- J Huang
- J Yang
- J Yang
- J Yang
- J. Margriet Collée
- JA Webster
- Javier Benitez
- JC Barrett
- Jenny A. Visser
- Jenny Chang-Claude
- JF Degner
- Jing Hua Zhao
- Jinhui Chen
- Joanne M. Murabito
- Joe Dennis
- Johan G. Eriksson
- John L. Hopper
- John P. Rice
- John R. B. Perry
- Jonathan Tyrer
- Jouke-Jan Hottenga
- JR Gibbs
- Julia A. Knight
- Julian Peto
- Julie E. Buring
- K Estrada
- K Hao
- K Michailidou
- Kamila Czene
- Kari Stefansson
- Kathryn L. Lunetta
- Katri Pylkäs
- Kay-Tee Khaw
- Ken K. Ong
- KS Kompass
- Kyriaki Michailidou
- L Liang
- Laura Crisponi
- Laura J. Bierut
- Laura M. Yerges-Armstrong
- Lavinia Paternoster
- LB Barreiro
- LFG Silveira
- Lili Milani
- Lisette Stolk
- Lude Franke
- Luigi Ferrucci
- Lynda M. Rose
- M Horikoshi
- M Rantalainen
- Maartje J. Hooning
- Mads Melbye
- Manjeet K. Bolla
- Marek Zygmunt
- Margaret J. Wright
- Marjanka K. Schmidt
- Marjo-Riitta Järvelin
- Mark I. McCarthy
- Massimo Mangino
- Matthias W. Beckmann
- Meir J. Stampfer
- Melanie Waldenberger
- Melissa E. Garcia
- Mellissa C. Southey
- Michael J. Econs
- Montserrat García-Closas
- Munro Peacock
- N Ruf
- Najaf Amin
- Nancy L. Pedersen
- Natalia Tšernikova
- Nicholas G. Martin
- Nicholas J. Timpson
- Nicholas J. Wareham
- Nora Franceschini
- P Prentice
- Paolo Gasparini
- Paolo Peterlongo
- Paolo Radice
- Pascal Guénel
- Patrick F. McArdle
- Patrick Neven
- Patrick Sulem
- Patrik K. Magnusson
- Paul D. P. Pharoah
- Paul M. Ridker
- Per Hall
- Peter A. Fasching
- Peter Devilee
- Peter Kraft
- Peter Vollenweider
- Q Li
- Qin Wang
- Reedik Mägi
- Robert Winqvist
- Robin Haring
- Roger L. Milne
- RP Grinspon
- RS Huang
- RSN Fehrmann
- Ruth J. F. Loos
- S Cho
- S Constantin
- S Sulzbacher
- Sandra Lai
- Sanela Kjellqvist
- SE Parker
- Serena Sanna
- Sheila Ulivi
- Stefania Bandinelli
- Stephen Chanock
- Stig E. Bojesen
- Suiqun Guo
- Susan Ring
- Sven Bergmann
- T Kwan
- T Maeda
- T Zeller
- Tamara B. Harris
- Tanguy Corre
- Tatiana Foroud
- Teresa Ferreira
- Thorkild I. A. Sørensen
- Tim D. Spector
- Tune H. Pers
- Tõnu Esko
- Ulla Sovio
- Unnur Thorsteinsdottir
- Ute Hamann
- V Emilsson
- Veikko Salomaa
- Veli-Matti Kosma
- Vilmundur Gudnason
- W Zheng
- Wei Q. Ang
- Wendy L. McArdle
- Y Idaghdour
- Y Stelzer
- Z Zadik
- Zoltan Kutalik
- Publication venue
- Nature Publishing Group
- Publication date
- 01/01/2014
- Field of study
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortality. Studies of rare human disorders of puberty and animal models point to a complex hypothalamic-pituitary-hormonal regulation, but the mechanisms that determine pubertal timing and underlie its links to disease risk remain unclear. Here, using genome-wide and custom-genotyping arrays in up to 182,416 women of European descent from 57 studies, we found robust evidence (P < 5 × 10(-8)) for 123 signals at 106 genomic loci associated with age at menarche. Many loci were associated with other pubertal traits in both sexes, and there was substantial overlap with genes implicated in body mass index and various diseases, including rare disorders of puberty. Menarche signals were enriched in imprinted regions, with three loci (DLK1-WDR25, MKRN3-MAGEL2 and KCNK9) demonstrating parent-of-origin-specific associations concordant with known parental expression patterns. Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid and γ-aminobutyric acid-B2 receptor signalling, among novel mechanisms that regulate pubertal timing in humans. Our findings suggest a genetic architecture involving at least hundreds of common variants in the coordinated timing of the pubertal transition
Introduction to the special issue "in-depth study of air pollution sources and processes within Beijing and its surrounding region (APHH-Beijing)"
- Author
- Allan J
- Barlow J
- Barratt B
- Beddows D
- Bloss WJ
- Calzolai G
- Carruthers D
- Carslaw DC
- Chan Q
- Chatzidiakou L
- Chen Y
- Coe H
- Crilley L
- Dai T
- Demuzere M
- Doherty R
- Duan F
- Dunmore RE
- Fu P
- Ge B
- Ge M
- Grimmond S
- Guan D
- Hamilton JF
- Han Y
- Harrison RM
- He K
- Heal M
- Heard D
- Hollaway M
- Hu M
- Ji D
- Jiang X
- Joe Acton W
- Jones R
- Kalberer M
- Kelly FJ
- Kotthaus S
- Kramer L
- Langford B
- Lee J
- Lewis AC
- Li J
- Li W
- Lin C
- Liu D
- Liu H
- Liu J
- Loh M
- Lu K
- Lucarelli F
- Mann G
- McFiggans G
- Miller MR
- Mills G
- Monk P
- Nemitz E
- Nicholas Hewitt C
- O'Connor F
- Ouyang B
- Palmer PI
- Percival C
- Popoola O
- Reeves C
- Ren L
- Rickard AR
- Shao L
- Shi G
- Shi Z
- Spracklen D
- Stevenson D
- Sun Y
- Sun Z
- Tao S
- Tong S
- Vu T
- Wang Q
- Wang W
- Wang X
- Wang X
- Wang Y
- Wang Z
- Wei L
- Whalley L
- Wild O
- Wu X
- Wu Z
- Xie P
- Yang F
- Yue S
- Zhang Q
- Zhang Y
- Zhang Y
- Zheng M
- Zhu T
- Publication venue
- Atmospheric Chemistry and Physics
- Publication date
- 01/01/2019
- Field of study
© 2019 Author(s). The Atmospheric Pollution and Human Health in a Chinese Megacity (APHH-Beijing) programme is an international collaborative project focusing on understanding the sources, processes and health effects of air pollution in the Beijing megacity. APHH-Beijing brings together leading China and UK research groups, state-of-the-art infrastructure and air quality models to work on four research themes: (1) sources and emissions of air pollutants; (2) atmospheric processes affecting urban air pollution; (3) air pollution exposure and health impacts; and (4) interventions and solutions. Themes 1 and 2 are closely integrated and support Theme 3, while Themes 1-3 provide scientific data for Theme 4 to develop cost-effective air pollution mitigation solutions. This paper provides an introduction to (i) the rationale of the APHH-Beijing programme and (ii) the measurement and modelling activities performed as part of it. In addition, this paper introduces the meteorology and air quality conditions during two joint intensive field campaigns-a core integration activity in APHH-Beijing. The coordinated campaigns provided observations of the atmospheric chemistry and physics at two sites: (i) the Institute of Atmospheric Physics in central Beijing and (ii) Pinggu in rural Beijing during 10 November-10 December 2016 (winter) and 21 May-22 June 2017 (summer). The campaigns were complemented by numerical modelling and automatic air quality and low-cost sensor observations in the Beijing megacity. In summary, the paper provides background information on the APHH-Beijing programme and sets the scene for more focused papers addressing specific aspects, processes and effects of air pollution in Beijing
Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib
- Author
- A Ashworth
- A Ciccia
- A Goncalves
- A Sancar
- A Tutt
- A Tutt
- AA Rodriguez
- Alan Ashworth
- AM Mendes-Pereira
- Anneleen Daemen
- B Koberle
- B Weigelt
- C Hatzis
- C Loveday
- CHEK2 Breast Cancer Case-Control Consortium
- Christopher J. Lord
- CT Williamson
- Denise M. Wolf
- E Vilar
- GJ Williams
- H Farmer
- H Holstege
- H Liang
- HC Reinhardt
- HC Reinhardt
- HE Bryant
- James E. Korkola
- JD Iglehart
- Jessica R. Frankum
- Joe W. Gray
- Jorge S. Reis-Filho
- K Gudmundsdottir
- KA Gelmon
- KW Caldecott
- Lakshmi R. Jakkula
- Laura J. van’t Veer
- LH Saal
- LM Heiser
- LM McShane
- M Graeser
- M Guha
- M Rouleau
- N McCabe
- N Turner
- NC Turner
- Nicholas J. Wang
- O Fletcher
- Obi L. Griffith
- P Domagala
- Paul T. Spellman
- PC Fong
- Q Wen
- R Buisson
- R Plummer
- R Tibes
- Rachael Natrajan
- Rachel Brough
- RM Neve
- S Moulder
- S Okano
- S Vinayak
- SL Edwards
- T Rich
- T Zaremba
- X Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
- Beugelsdijk Tony J.
- Bhakta Rita
- Bhuchar Venita
- Bi Shihua
- Bian Xuemeng
- Bieri Tamberlyn
- Bimage Kesha E.
- Bird Christine
- Birditt Brian
- Birney Ewan
- Birney Ewan
- Birren Bruce
- Bissell Helen
- Biswalo Kaneza
- Bituin Aleksandr
- Black Stacey
- Blackburne-Maze Suzanne
- Blair Jessica Anne
- Blakey Sarah
- Blanks Tia
- Blasiar Darin
- Blazej Robert
- Blitshsteyn Berta
- Blomstrom David B.
- Bloom Scott
- Bloom Toby
- Blumer Heather
- Blye Jason
- Blyth Peter R.
- Blöcker Helmut
- Boatright Elizabeth
- Boehm John
- Boen Juanan
- Boguslavskiy Leonid
- Bolton Christel
- Bolund Lars
- Bondoc Marnel
- Bonfield James
- Bonnett Ralph
- Bonnin David
- Border Richard
- Borowsky Mark
- Borzym Katja
- Boukhgalter Boris
- Bowen Eric
- Bradley Amanda
- Bradshaw-Cordum Holly
- Brady Nicola
- Brandriff Brigitte F.
- Brannon Wade
- Branscomb Elbert
- Bray Jason
- Bray-Allen Sarah
- Brettin Thomas
- Bridgeman Anne
- Bridgers Michael
- Brimhall Angela K.
- Brokstein Peter
- Brook Jonathan
- Brooking Shane
- Brottier Philippe
- Brown Andrew
- Brown Clive
- Brown Jacqui
- Brown Margaret
- Brown Mary
- Brown Mary J.
- Brown Michael
- Brown Nancy C.
- Bruce David D.
- Bruce Robert
- Bruno William J.
- Bruskiewich Richard
- Bryant Jackie
- Bryant Jennifer E.
- Bryant Nathaniel P.
- Brüls Thomas
- Buatsi Delali
- Buck David
- Buckingham Judith M.
- Buckle Veronica
- Buczek Donald
- Budd Claire
- Buhay Christian J.
- Bulbul Kerem
- Buller Sarah
- Bunker Nathan
- Burberry Jill
- Burch Paula Ellen
- Burford Deborah
- Burgess Joanne
- Burgin Matt
- Burkett Carrie E.
- Burkhart-Schultz Karolyn
- Burrell Kevin L.
- Burrill Wayne
- Burrows Christine
- Burton Christine
- Burton John
- Butcher Phil
- Butler Adam
- Butler Jon
- Butler Paul
- Caenepeel Sean
- Cahill Patrick
- Cai Tianjing
- Cai Zhen
- Cairns Murray
- Calderon Eliana
- Callen David F.
- Camarata Jody
- Camire David
- Camm Nick
- Campbell Christopher
- Campbell Connie S.
- Campbell Evelyn W.
- Campbell Mary I.
- Campbell Mary L.
- Campo Kevin
- Canning Bruno
- Cao Ting
- Cao Yuzhu
- Caoile Chenier
- Cardenas Faviola
- Cardenas Lolo
- Cardenas Veronica
- Carder Carol
- Carder Paul
- Carpenter Kelly
- Carrano Anthony V.
- Carriere Jason
- Carter Jason
- Carter Kelvin
- Carter Nigel
- Caruso Lauren
- Casias Kristal
- Cattolico Laurence
- Cavanna Tamara
- Cavazos Iracema
- Cavazos Sandra R.
- Ceasar Heather
- Cedroni Maria
- Cepeda Mario
- Chacko Joseph
- Chain Patrick
- Chalk Shani
- Challacombe Jean F.
- Chan Ka
- Chan Sheryl N.
- Chan Yee Man
- Chang Jean L.
- Chapman Jarrod
- Chapman Joanna
- Chapple Jeffrey
- Charles Rachel
- Chasteen Leslie A.
- Chavarria Simeon
- Chazaro Bruno
- Chen Baoxian
- Chen Bin
- Chen Chira
- Chen Chong
- Chen Chong
- Chen Chun-Nan
- Chen Cong
- Chen Ellson
- Chen Hsiu-Chuan
- Chen Jianlong
- Chen Jie
- Chen Jin
- Chen Junbao
- Chen Lihong
- Chen Lixia
- Chen Ray
- Chen Shu
- Chen Tong
- Chen Xiaoyun
- Chen Xinyi
- Chen Yanjiong
- Chen Yiyu
- Chen Zhu
- Chen Zhu
- Chen Zhu
- Cheng Jan-Fang
- Cheng Zhihua
- Chertkov Olga
- Cheshatsang Yama
- Chi Cheng
- Chi Han C.
- Chillingworth Neil
- Chin Sylvia
- Chinn Corey
- Chinwalla Asif
- Chissoe Stephanie
- Chiu Sally
- Chothia Tom
- Christensen Mari
- Christopoulos Constantine
- Chu Joseph
- Chui Connie
- Chung A
- Cinkowsky Michael J.
- Citroen Mieke
- Clack Rob
- Clamp Michele
- Clark Anthea
- Clark Graham
- Clark Kevin
- Clark Lynn
- Clark Lynn M.
- Clark Richard
- Clark Sarah
- Clark Sue
- Clarke Adrian
- Clarke Betty
- Clarke Eddie
- Clarke Kay
- Clarke Laura
- Clawson Hiram
- Clee Chris
- Clegg Shelia
- Clerc Blankenburg Kerstin Petra
- Cleveland David
- Clifford Karen
- Clifton Sandra W.
- Coates Julia
- Cobley Victoria
- Cockrell Raynard
- Coffey Alison
- Cofield Jackie
- Coggill Penelope
- Cohn Judith D.
- Colayco Rick
- Cole Lotte
- Collier Rachael
- Collings Simon
- Collins Francis S.
- Collins John
- Collins Philip
- Collymore Al
- Colman Louise
- Combs Jessie
- Comstock Robin
- Cong Bin
- Conner Richard
- Connolly Anthony
- Connolly Karen
- Conquer Jennie
- Conrad Ansgar
- Conroy Donald
- Considine Tony
- Constance Doug
- Cook April
- Cook Leanna
- Cooke Patrick
- Cooper Jonathan
- Cooper Rachel
- Cooper Robert
- Copeland Alex
- Coppola Maria
- Copsey Teresa
- Corby Nicole
- Cordes Matt
- Cordray Rebecca
- Cornell Christine
- Cornell Earl
- Cornell Linda
- Cornell Ruth
- Corum Ben
- Cottage Amanda
- Cotton Sara
- Coulson Alan
- Couronne Olivier
- Courtney Laura P.
- Coville Gez
- Cox Anthony
- Cox Caroline D.
- Cox Tony
- Coxhill Robert
- Coyle Marcus D.
- Craig Matthew
- Crane Tom
- Crawford Amanda L.
- Crawley Matt
- Cree Andrew
- Crespeau Hervé
- Crew Victor
- Critchlow Terrance
- Critz Paul
- Cruaud Corinne
- Cuff James
- Cui Hongjuan
- Cui Jinhui
- Cui Peng
- Cui Peng
- Culley Karl
- Cummings Auli
- Cummings Kirsti
- Cummings Paul
- Cummings Stephanie
- Cuomo Christina A.
- Curran Adam
- Curwen Valery
- Cutts Jeffrey
- Czubayko Martin
- D\u27Souza Lisa Marie
- Da Silva Corinne
- Dai Li
- Dalin Eillen
- Dang Michelle
- Danganan Linda
- Daniels Rachael
- Dathorne Stephanie R.
- Daum Christopher
- David Robert
- Davidson Lucy
- Davidson Stuart
- Davies Jonathon
- Davies Joy
- Davies Nicholas
- Davies Robert
- Davila Mary Louise
- Davis Candi Mon\u27et
- Davis Cheryl
- Davis Clay
- Davis Jayne
- Davis John
- Davis Matthew
- Davy-Carroll Latarsha
- Dawoe Tenzin
- Dawson Elisabeth
- De Anda Claudia
- De Latorre Andrea
- Deadman Rebecca
- Dean Peter
- Dear Simon
- Dearden Frances
- DeArellano Kurt
- Deaven Larry I.
- Deaven Larry L.
- Deere Kerry
- DeGray Stewart
- Degusta David
- Deguzman Maria
- Dehal Paramvir
- Delgado Marcos
- Delgado Oliver
- Delhaunty Kimberley
- Deloukas Panos
- Deng Yajun
- Dennis Janet
- Denson Shawn
- Denys Mirian
- Deramo Christine
- Desai Anu
- Detter John C.
- Devlin Laurie
- Dewar Ken
- Dhami Pawandeep
- Dhongsar Chemey
- Dias Jennifer
- Dias Victoria
- Dibartolo Genevieve
- Dibling Catherine
- Dickson Mark
- Diekhans Mark
- Dietz-Band Jeanne
- Digennaro Richard
- Dilts Karen
- Dimitrijevic-Bussod Mira
- Ding Hao
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- Ding Li
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- Dinh Huyen H.
- Dixon Kami
- Do Long
- Dobbs Ruth
- Dobson Richard
- Dockree Catherine
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- Dodsworth Steven
- Doggett Norman
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- Dong Hui
- Dong Kimberly
- Dong Wei
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- Dong Xiaojia
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- Doucette-Stamm Lynn
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- Du Feiyu
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- Dubchak Inna
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- Dunwell Erin
- Dupes Alan
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- Dutta Ireena
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- Eckenberg Ralph
- Edgar Darren
- Edionwe Susan Omwanghe Osayanro
- Edwards Carol
- Edwards Jennifer
- Edwards Karen
- Egan Amy
- Eichler Evan
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- Ejima Fumio
- Elkin Chris
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- Elliot Jeffrey
- Ellwood Matthew
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- Emelianenko Natalia
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- Faro Susan
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- Fawcett Joseph J.
- Fechtel Kim
- Fellingham Charlotte
- Felming Claire
- Felsenfeld Adam
- Feltwell Theresa
- Feng Guodong
- Feng Haiyan
- Feng Jie
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- Fennell Stephen
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- Fernando Pushpa Ranjani
- Ferriera Pat
- Fertitta Anne
- Fey Jim
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- Finn Robert
- Fischer Heather
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- Forbes Lisa D.
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- Fu Gang
- Fu Qiushi
- Fujioka Michiru
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- Fukawa Rintaro
- Fuller Liam
- Fuller Sharin
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- Fulton Lucinda A.
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- Förste Silke
- Gabisi Abdul M.
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- Gao Anwu
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- Garcia Carmen
- Garcia Emilio
- Garcia Marvin
- Garcia Ricardo M, III
- Garcia-Martinez Antonio
- Gardner Alison
- Gardner Alison
- Garduno Consuelo
- Gardyna Steph
- Garner Patrick
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- Gatland Leigh
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- Georgescu Anca
- Geotina Amy
- Ghori Jilur
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- Gibbs Ben
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- Gifford Mary
- Gil Isaias
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- Gingrich Jeff
- Giovanelli Kira
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- Glithero Rebecca
- Glöckner Gernot
- Gnerre Sante
- Gnirke Andreas
- Gold Darren
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- Gong Guanghui
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- Goodwin Lynne A.
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- Graham Joe
- Grandbois Edward
- Grant Jennifer
- Grant Michael
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- Gray Bruce
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- Green Lisa
- Greenhalgh James
- Greenhill Joe
- Gregg Philippa
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- Grewal Nennu
- Gribble Susan
- Griffith Jeffrey K.
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- Griffiths Ed
- Griffiths Mark
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- Grigoriev Igor
- Grimwood Jane
- Grocock Russell
- Groza Matthew
- Gu Jingli
- Gu Jun
- Gu Jun
- Gu Wenyi
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- Gu Xiaochang
- Guan Qiaoning
- Guarin Hannibal
- Guel Metzalli
- Guerra William
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- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
- Guo Jane
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- Gustafson Erik
- Guthrie Ian
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- Gwilliam Rhian
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- Gyapay Gábor
- Görlich Yvonne
- Ha Chi
- Hafez Nabil
- Haglund Krista
- Hagopian Daniel
- Hagos Birhane
- Haim Allen
- Hajek Patrick
- Hall Brett Lynn
- Hall Brittany
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- Hall Rebekah
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- Halls Karen
- Hallsworth-Pepin Kym
- Hamada Junko
- Hamilton Cerissa
- Hamilton Keelan A.
- Hamilton Matt
- Hamlett John
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- Han Guiqing
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- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
- Harper Georgina
- Harper Patrik
- Harradence Grant
- Harris Anthony
- Harrison Charlene-Lou
- Harrison Elliot
- Harrison Ruth
- Hart Elizabeth
- Hasegawa Tomoko
- Hashimoto Etsuko
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- Hatcher Beath
- Hattori Masahira
- Haugen Eric
- Haussler David
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- Hawkins Natalie
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- He Lin
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- Heath Paul
- Heathcott Rosemary
- Heilig Roland
- Heiner Cheryl
- Heinze Ivonne
- Heitmann Katja
- Helfenbein Keven
- Heller Andrew
- Hellsten Uffe
- Hembry Cathy
- Henderson Carl
- Henderson Nicholas
- Henderson Nina
- Hendrix David
- Hennig Steffen
- Henning Karla
- Hepa Victor
- Herd Tim
- Herman Charles
- Hernandez Judith
- Hernandez Omar
- Herseim Allyson
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- Heyen Joshua
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- Hildebrand Carl E.
- Hillier LaDeana
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- Holden Jane
- Holdgate Janet
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- Hooper Alison
- Hopewell Lucy
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- Hornett Gary
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- Hornsby Tony
- Horsley Sharon
- Horton Roger
- Hosage-Norman Catherine
- Hosoda Kei
- Hosono Katsuhiro
- Hosseini Roya
- Hou Shunfang
- Hou Xiaodi
- Houde Nathan
- Howard Philip
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- Howden Philip
- Howe Kevin
- Howell Gareth
- Howell Latoya Lynette
- Howells Sally Lucinda
- Hsu Fan
- Hu George
- Hu Jie
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- Huang Fang
- Huang Guyang
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- Huang Mei
- Huang Wayne
- Huang Wei
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- Huang Zhengping
- Hubbard Timothy
- Huber James W.
- Huckle Elizabeth
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- Ito Noriko
- Itoh Takehiko
- Iwakawa Shinobu
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- Iwatsu Mikiko
- Iyer Vivek
- Izatt Janet
- Izmajlowicz Monica
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- Jacintho Mark
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- Jahn Niels
- Jaklevic Joseph
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- James Kent W.
- Jareborg Niclas
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- Jassal Bijay
- Jeffery Grant
- Jeffery Kim
- Jeffrey Colin
- Jekosch Kerstin
- Jenkins Lee
- Jett Jamie
- Jewett Phillip E.
- Jia Jia
- Jia Jia
- Jia Nan
- Jia Xingchang
- Jiang Lu
- Jiang Yanrui
- Jiang Ziyou
- Jimenez Alberto
- Jin Jian
- Jin Yetao
- Jin Yongsan
- Johansen Tina
- Johnson Bennie
- Johnson Cheryl
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- Johnson David
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- Johnson Lori
- Johnson Mark
- Johnson Philip
- Johnson Rudy
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- Jolivet Angela
- Jolley Keith
- Jones Abigail
- Jones Charlien
- Jones Claire
- Jones Juliet
- Jones Matthew
- Jones Michael
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- Jones Steven
- Jong Pieter De
- Jordan Yun
- Joseph Shirin
- Joy Ann
- Joy Linsey
- Joy Victoria
- Joyce Gillian
- Jubb Mark
- Jung Eugine
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- Kadner Kristen
- Kagan Ryan
- Kahsai Orsalem
- Kaida Kaoru
- Kale Pat
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- Kamal Michael
- Kamat Asha
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- Kana Arnold
- Kang Hui
- Kang Kelie
- Kang Ning
- Kapur Hitesh
- Karolchik Donna
- Karunaratne Kanchi
- Kasprzyk Arek
- Katayama Takujiro
- Kato Takako
- Kauer Gerhard
- Kaul Rajinder
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- Kawagoe Chiharu
- Kawasaki Kazuhiko
- Kay Michael
- Kaye Danielle
- Kearney Lyndal
- Keefe Damian
- Keen Gifford
- Keenan Stephen
- Kegelmeyer Laura
- Kegg Lisa
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- Kells Cristyn
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- Kelly Susan H.
- Kershaw Joanna
- Kettleborough Ross
- Keys David
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- Kidd Cathy
- Kierstan Peter
- Kieu Alix
- Kim Jennifer
- Kim Joomyeong
- Kim Kyung
- Kimball Heather
- Kimberley Andrew
- Kimura Moe
- King Andrew
- King Laquisha Monique
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- Kingswood Colin
- Kisamo Haika
- Kisner Peter
- Kitts Paul
- Kiyooka Miho
- Klages Sven
- Klingle Gillian
- Knights Andrew
- Kobayashi Mai
- Kodira Chinnappa
- Kohlberg Sara
- Kojima Kazuyasu
- Kolbe William
- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
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- Krawczyk Marie-Claude
- Kremitzki Colin
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- Kube Michael
- Kubischta Duane
- Kudoh Jun
- Kuehl Jennifer
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- Kuhn Carol
- Kulish Larissa
- Kuroki Yoko
- Kwan Chinnie
- Kyle Amy
- LaButti Kurt
- Lacombe Anne
- Lad Heena
- Lafrades Melanie
- Lagemann Dorothee
- Lai Jianghua
- Lai Teresa
- Laidlaw Philip
- Laing Michael
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- Lama Dawa
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- Lambart Christine
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- Lander Eric S.
- Landers Tom
- Langford Cordelia
- Lansang Christine
- Lao Victoria
- Lapidus Alla
- Larke Ben
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- Lawlor Stephanie
- Layman Dan
- Leal Belita
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- Lebow Heather
- Lee Byung-in
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- Lee Denise
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- Lee Kenneth
- Lee Lisa
- Lee Peter
- Legall Fitzherbert Henderson, III
- Leger Jean Pierre
- Lehman Karl
- Lehmann Rüdiger
- Lehoczky Jessica
- Lehrach Hans
- Lehvaslaiho Minna
- Lei Meng
- Lemke Johannes
- Lennon Gregory
- Leonard Shawn
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- Lesar Kendra
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- Li Lili
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- Li Shuangding
- Li Shuangli
- Li Shuping
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- Li Zaiping
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- Lindo Ken
- Lindquist K.
- Lindsay Sarah
- Lindstrom Kirsten
- LIne Matthew
- Ling Wei
- Linkowski Albert
- Linsdell Sally
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- Liu Boyong
- Liu Boyong
- Liu Cong
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- Liu Jing
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- Liu Wen
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- Liu Xinshe
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- Liu Yilin
- Liu Ying
- Liu Yu
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- Liu Zhanwei
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- Luo Chunqing
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- Löhnert Tschong-Hun
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- Nguyen Hoa
- Nguyen Le-Thu Dinh
- Nguyen Lisa
- Nguyen Minh
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- Nguyen Ngoc Bich
- Nguyen Thu
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- Novik Karen
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- O\u27Donnell Paula
- O\u27Donovan Daniel
- O\u27Leary Sinead
- O\u27Loughlin Jennifer
- O\u27Neill Keith
- Obayashi Izumi
- Obregon Melissa
- Oddone Paola
- Oddone Pierre
- Oddy Lachlan
- Odell Christopher
- Ogawara Etsuko
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- Oragunye Njideka
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- Zembeck Lisa
- Zeng Yixin
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- Zhang Guohua
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- Zhang Haiqing
- Zhang Haiqing
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- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
- Author
- Aalfs C.M. (Cora)
- Adamo P. (Pio) d'
- Adank M.A. (Muriel)
- Adenis C. (Claude)
- Adlard J.W. (Julian)
- Agata S. (Simona)
- Ahearn T. (Thomas)
- Aittomäki K. (Kristiina)
- Andrieu N. (Nadine)
- Andrulis I.L. (Irene L.)
- Anton-Culver H. (Hoda)
- Antoniou A.C. (Antonis C.)
- Arndt V. (Volker)
- Arnold N. (Norbert)
- Aronson K.J. (Kristan J.)
- Arun B.K. (Banu)
- Augustinsson A. (Annelie)
- Ausems M.G.E.M. (Margreet)
- Azzollini J.
- Barjhoux L. (Laure)
- Barnes D. (Daniel)
- Barouk-Simonet E. (Emmanuelle)
- Barrowdale D. (Daniel)
- Barwell J. (Julian)
- Baurand A. (Amandine)
- Baxter R. (Robert)
- Baynes C. (Caroline)
- Becher H. (Heko)
- Beesley J. (Jonathan)
- Belotti M. (Muriel)
- Bermisheva M. (Marina)
- Bernstein L. (Leslie)
- Berthet P. (Pascaline)
- Bertolone G. (Geoffrey)
- Bertrand O. (Ophélie)
- Białkowska K. (Katarzyna)
- Bignon Y.-J. (Yves-Jean)
- Birot A.-M. (Anne-Marie)
- Blok M.J. (Marinus J.)
- Blomqvist C. (Carl)
- Bock G.H. (Geertruida) de
- Bojesen S.E. (Stig)
- Bolla M.K. (Manjeet K.)
- Bonadona V. (Valérie)
- Bonnani B. (Bernardo)
- Bonnet F. (Françoise)
- Borg Å. (Åke)
- Bourdon V. (Violaine)
- Boutry-Kryza N. (N.)
- Bowtell D. (David)
- Brady A. (A.)
- Brauch H. (Hiltrud)
- Brenner H. (Hermann)
- Bressac-de Paillerets B. (Brigitte)
- Brewer C. (Carole)
- Bronner M. (Myriam)
- Bubien V. (Virginie)
- Buecher B. (Bruno)
- Burwinkel B. (Barbara)
- Buys S.S. (Saundra S.)
- Bézieau S. (Stéphane)
- Caldes T. (Trinidad)
- Calender A. (Alain)
- Caligo M.A. (Maria A.)
- Campa D. (Daniele)
- Campbell I. (Ian)
- Caputo S. (Sandrine)
- Caron O. (Olivier)
- Carpenter T.A. (Adrian)
- Carter B.D. (Brian D.)
- Castelao J.E. (Jose )
- Castera L. (Laurent)
- Chang-Claude J. (Jenny)
- Chanock S.J. (Stephen J.)
- Chenevix-Trench G. (Georgia)
- Chiesa J. (Jean)
- Chung W.K. (Wendy K.)
- Claes K.B.M. (Kathleen B. M.)
- Clarke C. (Christine)
- Clarke C.L. (Christine L.)
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- Hogervorst F.B.L. (Frans B. L.)
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- Ziogas A. (Argyrios)
- Zorn K.K. (Kristin K.)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/02/2021
- Field of study
Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies. Other mutation carrier-specific susceptibility variants may exist but studies of mutation carriers have so far been underpowered. We conduct a novel case-only genome-wide association study comparing genotype frequencies between 60,212 general population BC cases and 13,007 cases with BRCA1 or BRCA2 mutations. We identify robust novel associations for 2 variants with BC for BRCA1 and 3 for BRCA2 mutation carriers, P < 10−8, at 5 loci, which are not associated with risk in the general population. They include rs60882887 at 11p11.2 where MADD, SP11 and EIF1, genes previously implicated in BC biology, are predicted as potential targets. These findings will contribute towards customising BC polygenic risk scores for BRCA1 and BRCA2 mutation carriers
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
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- Arai Koji
- Araya Akito
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- Wu Chien-Ming
- Wu David S.
- Wu H.
- Wysocki Daniel
- Xiao Liting
- Yadav N.
- Yamada T.
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
- Yamamoto Takahiro
- Yamashita K.
- Yamazaki R.
- Yang Fengwei
- Yang Kate Z.
- Yang Le
- Yang Y. -C.
- Yang Yang
- Yang Yi
- Yap M. J.
- Yeeles D. W.
- Yeh S. -W.
- Yelikar A. B.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yoshioka T.
- Yu Hang
- Yu Haocun
- Yuzurihara H.
- Zadrożny A.
- Zahoor Jan Aasim
- Zanolin M.
- Zeidler Simon
- Zelenova T.
- Zendri J. -P.
- Zevin Michael
- Zhan M.
- Zhang H.
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Y.
- Zhao C.
- Zhao G.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
International Consensus Statement on Rhinology and Allergy: Rhinosinusitis
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- Parma V
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- Passali D
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- Patel NA
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- Patel ZM
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- Peng Y
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- Peric A
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- Perkasa MF
- Perloff JR
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- Pfaar O
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- Ramakrishnan V
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- Rostkowska‐Nadolska B
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- Rotenberg BW
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- Schreiber CP
- Schubert MS
- Schwartz HJ
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- Schwarzbach HL
- Schwitzguébel AJ‐P
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- Sedaghat AR
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- Seiberling K
- Seiberling KA
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- Sella GCP
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- Senior BA
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- Senturk M
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- Seresirikachorn K
- Servat JJ
- Seshadri S
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- Siegel GJ
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- Sirikci A
- Sitarek P
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- Sleigh MA
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- Small CB
- Smith A
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- Smith KA
- Smith KA
- Smith SS
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- Smith T
- Smith TL
- Smith TL
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- Smith TL
- Smith TL
- Smith TL
- Smith TL
- Snidvongs K
- Snidvongs K
- Snidvongs K
- Snidvongs K
- Snidvongs K
- Snidvongs K
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- Snidvongs K
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- Snow DG
- Snyderman CH
- Sohn HG
- Sohn JH
- Soler ZM
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- Soler ZM
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- Southwood JE
- Sowerby LJ
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- Stevens PR
- Stevens WW
- Stevens WW
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- Stevens WW
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- Stevenson DD
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- Stewart RA
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- Stryjewska‐Makuch G
- Su MC
- Subramanian HN
- Succar EF
- Sugimoto I
- Sugino T
- Suh JD
- Sullivan PW
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- Sunadome H
- Sundaresan AS
- Sunkaraneni VS
- Suzuki S
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- Sylvester DC
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- Tammemagi CM
- Tan BK
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- Tan KS
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- Tan NC
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- Tanaka S
- Tang C
- Tanner SB
- Tarrant BJ
- Tas M
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- Taulu R
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- Tay TR
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- Telmesani LM
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- Tewfik MA
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- Thamboo A
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- Thamboo A
- Tharakan A
- Theodoraki MN
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- Tizzano M
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- Todman MS
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- Tosun F
- Tournas A
- Tran Khai Hoan N
- Tripathi A
- Trompette A
- Tscopp KP
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- Turan A
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- Turner JH
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- Tyler MA
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- Tyler MA
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- Unlu HH
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- Zurlo JJ
- Zuskin E
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2021
- Field of study
Background: The 5 years since the publication of the first International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed foundational progress in our understanding and treatment of rhinologic disease. These advances are reflected within the more than 40 new topics covered within the ICAR‐RS‐2021 as well as updates to the original 140 topics. This executive summary consolidates the evidence‐based findings of the document. Methods: ICAR‐RS presents over 180 topics in the forms of evidence‐based reviews with recommendations (EBRRs), evidence‐based reviews, and literature reviews. The highest grade structured recommendations of the EBRR sections are summarized in this executive summary. Results: ICAR‐RS‐2021 covers 22 topics regarding the medical management of RS, which are grade A/B and are presented in the executive summary. Additionally, 4 topics regarding the surgical management of RS are grade A/B and are presented in the executive summary. Finally, a comprehensive evidence‐based management algorithm is provided. Conclusion: This ICAR‐RS‐2021 executive summary provides a compilation of the evidence‐based recommendations for medical and surgical treatment of the most common forms of RS
Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo
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- Zweizig John
- Álvarez-López S.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/08/2023
- Field of study
Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level
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