Ten-year course of treated bipolar I disorder: The role of polarity at onset

Introduction: Early-stage predictors of illness course are needed in bipolar disorder (BD). Differences among patients with a first depressive versus maniac/hypomanic episode have been stated, although in most studies, memory bias and time from onset to start of specialized treatment might interfere. The aim was to compare the first 10 years of illness course according to polarity at onset. Methods: 49 type I BD patients admitted for treatment for a first-time affective episode and a following 10-year attendance to the institution were included. A retrospective year by year comparison according to polarity at onset (depressive (DPO) or maniac (MPO)) was performed. Cramer's V and Cohen d were computed to determine effect size. Results: 59.2% (n = 29) started with MPO. Both groups were similar in demographic and social outcome characteristics, clinical features, and treatment variables. Patients with DPO reported more depressive episodes than MPO patients (U = 149.0 p < .001, Cohen's d = 0.87); both groups had a similar number of manic episodes. Only during the first year of follow-up, suicide attempts (SA) were more frequent in patients with DPO while the presence of a psychotic episode and psychiatric hospitalizations were more frequent in the MPO group. Conclusion: According to these findings, it can be concluded that illness onset is only indicative of depressive predominant polarity but is not related to other poor prognostic variables after the first year of illness onset, in treated BD. SA in the first year of an affective disorder could represent a marker of BD

Aportes desde el saber pedagógico para la educación del siglo XXI

199 p. libro digital*Presentación 8. *Soberanía del cuerpo y la subjetividad: un giro pedagógico en educación 12. *Transformación histórica y social del concepto de género en el aula: permanencias e irrupciones 32. *Experiencia Jóvenes líderes pares en salud sexual y reproductiva, Colegio El Jazmín IED 50. *Mentes Rebeldes: una experiencia de comunicación y pedagogía con enfoque de género 70. *El impacto de la tristeza melancólica en niñas y jóvenes estudiantes de secundaria y su influencia en el surgimiento de conflictos femeninos. Una reflexión a partir de la experiencia Torbellinos Guillermistas de Reflexión Femenina 92. *Educación sexual integral para las infancias, el reto pedagógico que el Colegio Juana Escobar IED está dispuesto a asumir 108. *Identidad(es), diversidad(es) y género: un acercamiento a las subjetividades juveniles en la escuela a través del performance 126. *Imaginarios y prácticas sobre diversidad sexual, una mirada sobre la normalización en el Colegio Germán Arciniegas IED 138. *Lenguaje, diversidad sexual y de género en el Colegio Sotavento IED 158. *Masculinidades: trasegando entre la tradicional y la actual. Dilemas como hombre 178.primera edicionLas opiniones son responsabilidad de los autores

Reflections Magazine of the Faculty of Education. Volume 7 No. 8 June 1999

Reflexiones presenta en esta entrega artículos escritos por profesores y alumnos de los programas de posgrado y pregrado de nuestra Facultad, en los cuales se plasma el espíritu de una comunidad académica deseosa de contribuir al desarrollo de lo humano, utilizando como pretexto puntos de referencia de orden ético y lógico, en consonancia con los ideales que propone, para el hacerteórico y práctico, el Proyecto Educativo de nuestra Universidad. Además, através deestas líneas iniciales, el comité curricular de la Facultad desea informar a los lectores sobre el proceso de autoevalución y acreditación que estamos viviendo, e invitar a los profesores y alumnos, al personal administrativo y a los egresados de esa facultad y a la comunidad académica de la escuelanormal de Bucaramanga, a participar en el análisis y consecuente reestructuración de los programas que ofrecemos.Reflections presents in this installment articles written by professors and students of the postgraduate and undergraduate programs of our Faculty, in which the spirit of an academic community eager to contribute to the development of the human being is embodied, using reference points of order as a pretext. ethical and logical, in line with the ideals proposed, for the theoretical and practical, the Educational Project of our University. In addition, through these initial lines, the Faculty's curricular committee wishes to inform readers about the self-evaluation and accreditation process that we are undergoing, and invite teachers and students, administrative staff and graduates of that Faculty and the academic community of the normal school of Bucaramanga, to participate in the analysis and consequent restructuring of the programs we offer

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV

A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe

Observation of tW production in the single-lepton channel in pp collisions at root s=13 TeV

A measurement of the cross section of the associated production of a single top quark and a W boson in final states with a muon or electron and jets in proton-proton collisions at root s = 13 TeV is presented. The data correspond to an integrated luminosity of 36 fb(-1) collected with the CMS detector at the CERN LHC in 2016. A boosted decision tree is used to separate the tW signal from the dominant t (t) over bar background, whilst the subleading W+jets and multijet backgrounds are constrained using data-based estimates. This result is the first observation of the tW process in final states containing a muon or electron and jets, with a significance exceeding 5 standard deviations. The cross section is determined to be 89 +/- 4 (stat) +/- 12 (syst) pb, consistent with the standard model.Peer reviewe

Measurements of the Electroweak Diboson Production Cross Sections in Proton-Proton Collisions at root s=5.02 TeV Using Leptonic Decays

The first measurements of diboson production cross sections in proton-proton interactions at a center-of-mass energy of 5.02 TeV are reported. They are based on data collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 302 pb(-1). Events with two, three, or four charged light leptons (electrons or muons) in the final state are analyzed. The WW, WZ, and ZZ total cross sections are measured as sigma(WW) = 37:0(-5.2)(+5.5) (stat)(-2.6)(+2.7) (syst) pb, sigma(WZ) = 6.4(-2.1)(+2.5) (stat)(-0.3)(+0.5)(syst) pb, and sigma(ZZ) = 5.3(-2.1)(+2.5)(stat)(-0.4)(+0.5) (syst) pb. All measurements are in good agreement with theoretical calculations at combined next-to-next-to-leading order quantum chromodynamics and next-to-leading order electroweak accuracy

Search for lepton-flavor violating decays of the Higgs boson in the mu tau and e tau final states in proton-proton collisions at root s=13 TeV

A search is presented for lepton-flavor violating decays of the Higgs boson to mu t and et. The dataset corresponds to an integrated luminosity of 137 fb(-1) collected at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV. No significant excess has been found, and the results are interpreted in terms of upper limits on lepton-flavor violating branching fractions of the Higgs boson. The observed (expected) upper limits on the branching fractions are, respectively, B(H -> mu t) e tau) < 0.22(0.16)% at 95% confidence level.Peer reviewe