48 research outputs found

    Experiments based on blue intensity for reconstructing North Pacific temperatures along the Gulf of Alaska

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    We gratefully acknowledge the National Science Foundation’s Paleoclimatic Perspectives on Climatic Change (P2C2) grant nos. AGS 1159430, AGS 1502186, AGS 1502150, and PLR 15-04134.Ring-width (RW) records from the Gulf of Alaska (GOA) have yielded a valuable long-term perspective for North Pacific changes on decadal to longer timescales in prior studies but contain a broad winter to late summer seasonal climate response. Similar to the highly climate-sensitive maximum latewood density (MXD) proxy, the blue intensity (BI) parameter has recently been shown to correlate well with year-to-year warm-season temperatures for a number of sites at northern latitudes. Since BI records are much less labour intensive and expensive to generate than MXD, such data hold great potential value for future tree-ring studies in the GOA and other regions in mid- to high latitudes. Here we explore the potential for improving tree-ring-based reconstructions using combinations of RW- and BI-related parameters (latewood BI and delta BI) from an experimental subset of samples at eight mountain hemlock (Tsuga mertensiana) sites along the GOA. This is the first study for the hemlock genus using BI data. We find that using either inverted latewood BI (LWBinv) or delta BI (DB) can improve the amount of explained temperature variance by > 10 % compared to RW alone, although the optimal target season shrinks to June–September, which may have implications for studying ocean–atmosphere variability in the region. One challenge in building these BI records is that resin extraction did not remove colour differences between the heartwood and sapwood; thus, long term trend biases, expressed as relatively warm temperatures in the 18th century, were noted when using the LWBinv data. Using DB appeared to overcome these trend biases, resulting in a reconstruction expressing 18th–19th century temperatures ca. 0.5 °C cooler than the 20th–21st centuries. This cool period agrees well with previous dendroclimatic studies and the glacial advance record in the region. Continuing BI measurement in the GOA region must focus on sampling and measuring more trees per site (> 20) and compiling more sites to overcome site-specific factors affecting climate response and using subfossil material to extend the record. Although LWBinv captures the inter-annual climate signal more strongly than DB, DB appears to better capture long-term secular trends that agree with other proxy archives in the region. Great care is needed, however, when implementing different detrending options and more experimentation is necessary to assess the utility of DB for different conifer species around the Northern Hemisphere.Publisher PDFPeer reviewe

    Last millennium northern hemisphere summer temperatures from tree rings: Part I: The long term context

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    Large-scale millennial length Northern Hemisphere (NH) temperature reconstructions have been progressively improved over the last 20 years as new datasets have been developed. This paper, and its companion (Part II, Anchukaitis et al. in prep), details the latest tree-ring (TR) based NH land air temperature reconstruction from a temporal and spatial perspective. This work is the first product of a consortium called N-TREND (Northern Hemisphere Tree-Ring Network Development) which brings together dendroclimatologists to identify a collective strategy for improving large-scale summer temperature reconstructions. The new reconstruction, N-TREND2015, utilises 54 records, a significant expansion compared with previous TR studies, and yields an improved reconstruction with stronger statistical calibration metrics. N-TREND2015 is relatively insensitive to the compositing method and spatial weighting used and validation metrics indicate that the new record portrays reasonable coherence with large scale summer temperatures and is robust at all time-scales from 918 to 2004 where at least 3 TR records exist from each major continental mass. N-TREND2015 indicates a longer and warmer medieval period (∼900–1170) than portrayed by previous TR NH reconstructions and by the CMIP5 model ensemble, but with better overall agreement between records for the last 600 years. Future dendroclimatic projects should focus on developing new long records from data-sparse regions such as North America and eastern Eurasia as well as ensuring the measurement of parameters related to latewood density to complement ring-width records which can improve local based calibration substantially

    Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

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    Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

    Tree rings reveal globally coherent signature of cosmogenic radiocarbon events in 774 and 993 CE

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    This study was funded by the WSL-internal COSMIC project (5233.00148.001.01), the ETHZ (Laboratory of Ion Beam Physics), the Swiss National Science Foundation (SNF Grant 200021L_157187/1), and as the Czech Republic Grant Agency project no. 17-22102s.Though tree-ring chronologies are annually resolved, their dating has never been independently validated at the global scale. Moreover, it is unknown if atmospheric radiocarbon enrichment events of cosmogenic origin leave spatiotemporally consistent fingerprints. Here we measure the 14C content in 484 individual tree rings formed in the periods 770–780 and 990–1000 CE. Distinct 14C excursions starting in the boreal summer of 774 and the boreal spring of 993 ensure the precise dating of 44 tree-ring records from five continents. We also identify a meridional decline of 11-year mean atmospheric radiocarbon concentrations across both hemispheres. Corroborated by historical eye-witness accounts of red auroras, our results suggest a global exposure to strong solar proton radiation. To improve understanding of the return frequency and intensity of past cosmic events, which is particularly important for assessing the potential threat of space weather on our society, further annually resolved 14C measurements are needed.Publisher PDFPeer reviewe

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Bishop Estate's Kakaako project gains support

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    A quantitative study exploring grading and assessment practices in the middle school environment

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    Educators are committed to providing students the best possible education by using the practices and tools they know (Zmuda, Kuklis, & Kline, 2004). Unfortunately, the status quo for grading and assessment practices is faulty, outdated, and ineffective. Current practices have unwittingly hindered student progress and motivation (O'Connor, 2007). Educational leaders, administrators, and teachers are faced with questions regarding the best ways to motivate students and accurately report their progress (Popham, 2011). Assessing and grading student achievement are primary functions of educators and if these practices are not approached and applied properly, a grade can misrepresent the true knowledge of the student regarding class standards (Brookhart, 2009). Even though there has been a shift to standards based teaching, grading and assessment practices have not followed suit and continue to lag behind (Zmuda, Kuklis, & Kline, 2004). Conventional grading and assessment practices abound, yet opportunities for the introduction of reform and the necessary professional development for the implementation and sustainability of such reform are lacking (Wormeli, 2006). Second order change is an apparent break from the past and is best presented and maintained through quality, ongoing professional development (Marzano, 2003). Change is inevitable and necessary at times, offering fresh perspective and new ideas, and it is the responsibility of those in the teaching profession to continue to learn and stay apprised of current research to give students the best possible education (Schimmer, 2012). When a district or school becomes aware of the need for change, there is an obligation to address the underlying issues and all relevant facts, logic, and research. Professional development provides the optimal venue for learning, discussing, applying, and evaluating any proposed changes (DuFour & Marzano, 2011). Reeves (2007) asked, "What is the risk if we engage in this change compared to the risk of continuing our present practice" (p. 7). The risk of embracing a proposed change may include limited buy-in, fear of failure, or the perception of more work. Regardless of potential effects, growth can only come through change, and trying new methods is the only way to know what changes work (Schimmer, 2012). The continuation of current grading practices poses a threat to the educational process and the future of student learning by undermining motivation and presenting inaccurate information due to grades' convoluted nature (Brookhart, 2009). Grades should not represent tradition, opinion, behavior, effort, homework, attendance, or any other extra-curricular components (O'Connor, 2007). They should purely and simply report the student's comprehension of predetermined class standards and goals (Brookhart, 2009). There are new research based methods for grading and assessment that honor the meaning of the grade and could be introduced and implemented in schools across the country through professional development opportunities (Reeves, 2007). The purpose of this study was to investigate the perceptions of grading and assessment practices in Fall River Middle School and to analyze the impact of increased opportunities for professional development in grading and assessment practices on the staff

    Protest at Hamakua auction

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