261 research outputs found

    Variable length-based genetic representation to automatically evolve wrappers

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    The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-12433-4_44Proceedings 8th International Conference on Practical Applications of Agents and Multiagent SystemsThe Web has been the star service on the Internet, however the outsized information available and its decentralized nature has originated an intrinsic difficulty to locate, extract and compose information. An automatic approach is required to handle with this huge amount of data. In this paper we present a machine learning algorithm based on Genetic Algorithms which generates a set of complex wrappers, able to extract information from theWeb. The paper presents the experimental evaluation of these wrappers over a set of basic data sets.This work has been partially supported by the Spanish Ministry of Science and Innovation under the projects Castilla-La Mancha project PEII09-0266-6640, COMPUBIODIVE (TIN2007-65989), and by V-LeaF (TIN2008-02729-E/TIN)

    Solar Influence on Nuclear Decay Rates: Constraints from the MESSENGER Mission

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    We have analyzed Cs-137 decay data, obtained from a small sample onboard the MESSENGER spacecraft en route to Mercury, with the aim of setting limits on a possible correlation between nuclear decay rates and solar activity. Such a correlation has been suggested recently on the basis of data from Mn-54 decay during the solar flare of 13 December 2006, and by indications of an annual and other periodic variations in the decay rates of Si-32, Cl-36, and Ra-226. Data from five measurements of the Cs-137 count rate over a period of approximately 5.4 years have been fit to a formula which accounts for the usual exponential decrease in count rate over time, along with the addition of a theoretical solar contribution varying with MESSENGER-Sun separation. The indication of solar influence is then characterized by a non-zero value of the calculated parameter \xi, and we find \xi=(2.8+/-8.1)x10^{-3} for Cs-137. A simulation of the increased data that can hypothetically be expected following Mercury orbit insertion on 18 March 2011 suggests that the anticipated improvement in the determination of \xi could reveal a non-zero value of \xi if present at a level consistent with other data.Comment: Accepted for publication in Astrophysics and Space Science, 2011. 7 pages, 5 figures. Version 2 has corrected Figure 1, since Fig. 1 did not appear correctly in Version

    Mitochondrial dysfunction in CA1 hippocampal neurons of the UBE3A deficient mouse model for Angelman syndrome

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    Angelman syndrome (AS) is a severe neurological disorder caused by a deficiency of ubiquitin protein ligase E3A (UBE3A), but the pathophysiology of the disease remains unknown. We now report that in the brains of AS mice in which the maternal UBE3A allele is mutated (m-) and the paternal allele is potentially inactivated by imprinting (p+) (UBE3A m-p+), the mitochondria are abnormal and exhibit a partial oxidative phosphorylation (OXPHOS) defect. Electron microscopy of the hippocampal region of the UBE3A m-p+ mice (n=6) reveals small, dense mitochondria with altered cristae, relative to wild-type littermates (n=6) and reduced synaptic vesicle density. The specific activity of OXPHOS complex III is reduced in whole brain mitochondria in UBE3A m-p+ (n=5) mice versus wild-type littermates (n=5). Therefore, mitochondrial dysfunction may contribute to the pathophysiology of Angelman syndrome

    Similar neural pathways link psychological stress and brain-age in health and multiple sclerosis

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    Clinical and neuroscientific studies suggest a link between psychological stress and reduced brain health in health and neurological disease but it is unclear whether mediating pathways are similar. Consequently, we applied an arterial-spin-labeling MRI stress task in 42 healthy persons and 56 with multiple sclerosis, and investigated regional neural stress responses, associations between functional connectivity of stress-responsive regions and the brain-age prediction error, a highly sensitive machine learning brain health biomarker, and regional brain-age constituents in both groups. Stress responsivity did not differ between groups. Although elevated brain-age prediction errors indicated worse brain health in patients, anterior insula–occipital cortex (healthy persons: occipital pole; patients: fusiform gyrus) functional connectivity correlated with brain-age prediction errors in both groups. Finally, also gray matter contributed similarly to regional brain-age across groups. These findings might suggest a common stress–brain health pathway whose impact is amplified in multiple sclerosis by disease-specific vulnerability factors

    Supermassive Black Hole Binaries: The Search Continues

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    Gravitationally bound supermassive black hole binaries (SBHBs) are thought to be a natural product of galactic mergers and growth of the large scale structure in the universe. They however remain observationally elusive, thus raising a question about characteristic observational signatures associated with these systems. In this conference proceeding I discuss current theoretical understanding and latest advances and prospects in observational searches for SBHBs.Comment: 17 pages, 4 figures. To appear in the Proceedings of 2014 Sant Cugat Forum on Astrophysics. Astrophysics and Space Science Proceedings, ed. C.Sopuerta (Berlin: Springer-Verlag

    Pulsars as Fantastic Objects and Probes

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    Pulsars are fantastic objects, which show the extreme states of matters and plasma physics not understood yet. Pulsars can be used as probes for the detection of interstellar medium and even the gravitational waves. Here I review the basic facts of pulsars which should attract students to choose pulsar studies as their future projects.Comment: Invited Lecture on the "First Kodai-Trieste Workshop on Plasma Astrophysics", Kodaikanal Obs, India. Aug.27-Sept.7th, 2007. In: "Turbulence, Dynamos, Accretion Disks, Pulsars and Collective Plasma Processes". Get a copy from: http://www.springerlink.com/content/978-1-4020-8867-

    The influence of visual flow and perceptual load on locomotion speed

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    Visual flow is used to perceive and regulate movement speed during locomotion. We assessed the extent to which variation in flow from the ground plane, arising from static visual textures, influences locomotion speed under conditions of concurrent perceptual load. In two experiments, participants walked over a 12-m projected walkway that consisted of stripes that were oriented orthogonal to the walking direction. In the critical conditions, the frequency of the stripes increased or decreased. We observed small, but consistent effects on walking speed, so that participants were walking slower when the frequency increased compared to when the frequency decreased. This basic effect suggests that participants interpreted the change in visual flow in these conditions as at least partly due to a change in their own movement speed, and counteracted such a change by speeding up or slowing down. Critically, these effects were magnified under conditions of low perceptual load and a locus of attention near the ground plane. Our findings suggest that the contribution of vision in the control of ongoing locomotion is relatively fluid and dependent on ongoing perceptual (and perhaps more generally cognitive) task demands
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