Una Experiencia del Enfoque por Tareas en la Clase de Lengua Castellana y Literatura

El trabajo que presento está dividido en dos partes: una introducción teórica sobre el Enfoque por Tareas y la exposición de una experiencia docente poniendo en práctica dicho enfoque. Considero interesante la introducción teórica para explicar brevemente los puntos clave de este tipo de enseñanza innovadora, pues de este modo se comprenderá mejor el desarrollo de la experiencia. La segunda parte se subdivide en otras dos: la primera destinada a la explicación del desarrollo de una unidad didáctica de Lengua Castellana y Literatura a través de tareas y la segunda a una evaluación de la misma desde un punto de vista profesional y personal.Le travail queje présente se divise en deux parties: tout d'abord une introduction théorique sur l'enseignement "por tareas" (par "tareas" on entend les divers travaux qui sont donnés par l'enseignant et permettent d'apprendre une langue) et ensuite une exposition d'une expérience de mise en pratique de cet enseignement. L'introduction théorique me semble intéressante afín d'expliquer briévement les points clés de ce type d'enseignement novateur, ainsi on comprendra mieux, par la suite, le déroulement de l'expérience. La deuxiéme partie se subdivise en deux sous-parties: la premiére sous-partie est consacrée á l'explication du déroulement d'une unité didactique de Langue Castillane et Litterature au moyen des "tareas" et la deuxiéme a une évaluation de cette unité didactique selon un point de vue professionnel et un point de vue personnel

Una Experiencia del Enfoque por Tareas en la Clase de Lengua Castellana y Literatura

El trabajo que presento está dividido en dos partes: una introducción teórica sobre el Enfoque por Tareas y la exposición de una experiencia docente poniendo en práctica dicho enfoque. Considero interesante la introducción teórica para explicar brevemente los puntos clave de este tipo de enseñanza innovadora, pues de este modo se comprenderá mejor el desarrollo de la experiencia. La segunda parte se subdivide en otras dos: la primera destinada a la explicación del desarrollo de una unidad didáctica de Lengua Castellana y Literatura a través de tareas y la segunda a una evaluación de la misma desde un punto de vista profesional y personal.Le travail queje présente se divise en deux parties: tout d'abord une introduction théorique sur l'enseignement "por tareas" (par "tareas" on entend les divers travaux qui sont donnés par l'enseignant et permettent d'apprendre une langue) et ensuite une exposition d'une expérience de mise en pratique de cet enseignement. L'introduction théorique me semble intéressante afín d'expliquer briévement les points clés de ce type d'enseignement novateur, ainsi on comprendra mieux, par la suite, le déroulement de l'expérience. La deuxiéme partie se subdivise en deux sous-parties: la premiére sous-partie est consacrée á l'explication du déroulement d'une unité didactique de Langue Castillane et Litterature au moyen des "tareas" et la deuxiéme a une évaluation de cette unité didactique selon un point de vue professionnel et un point de vue personnel

Working memory performance, pain and associated clinical variables in women with fibromyalgia

Working memory (WM) is a critical process for cognitive functioning in which fibromyalgia (FM) patients could show cognitive disturbances. Dyscognition in FM has been explained by interference from pain processing, which shares the neural substrates involved in cognition and may capture neural resources required to perform cognitive tasks. However, there is not yet data about how pain is related to WM performance, neither the role that other clinical variables could have. The objectives of this study were (1) to clarify the WM status of patients with FM and its relationship with nociception, and (2) to determine the clinical variables associated to FM that best predict WM performance. To this end, 132 women with FM undertook a neuropsychological assessment of WM functioning (Digit span, Spatial span, ACT tests and a 2-Back task) and a complete clinical assessment (FSQ, FIQ-R, BDI-1A, HADS, PSQI, MFE-30 questionnaires), including determination of pain thresholds and tolerance by pressure algometry. Patients with FM seem to preserve their WM span and ability to maintain and manipulate information online for both visuospatial and verbal domains. However, up to one-third of patients showed impairment in tasks requiring more short-term memory load, divided attention, and information processing ability (measured by the ACT task). Cognitive performance was spuriously related to the level of pain experienced, finding only that pain measures are related to the ACT task. The results of the linear regression analyses suggest that sleep problems and fatigue were the variables that best predicted WM performance in FM patients. Future research should take these variables into account when evaluating dyscognition in FM and should include dynamic measures of pain modulationThis study was funded by the Spanish State Research Agency (Call: Retos 2016. Project reference: PSI2016-75313-R) and Consellería de Cultura, Educación e Universidades, Xunta de Galicia (Code: ED431C 2021/04)S

Comparative validation of three contemporary bleeding risk scores in acute coronary syndromes

Background: Hemorrhagic complications are strongly linked with subsequent adverse outcomes in acute coronary syndrome (ACS) patients. Various risk scores (RS) are available to estimate the bleeding risk in these patients. Aims: To compare the predictive accuracy of the three contemporary bleeding RS in ACS. Methods: We studied 4500 consecutive patients with ACS. For each patient, the ACTION, CRUSADE, and Mehran et al bleeding RS were calculated. We assessed their performance either for the prediction of their own major bleeding events or to predict the TIMI serious (major and minor) bleeding episodes in the overall population, in patients with non-ST elevation ACS (NSTEACS) and in those with ST-elevation myocardial infarction (STEMI) patients. Calibration (Hosmer-Lemeshow test) and discrimination (c-statistic) for the three RS were computed and compared. We used the concept of net reclassification improvement (NRI) to compare the incremental prognostic value of using a particular RS over the remaining scores in predicting the TIMI serious bleeding. Results: The best predictive accuracy was obtained by the CRUSADE score either for the prediction of its own major bleeding events (c-statistic=0.80, 0.791, and 0.81 for the entire sample, for STEMI, and for NSTEACS patients, respectively) or to predict the TIMI serious bleed occurrence (c-statistic=0.741, 0.738,and 0.745 for the whole population, for STEMI and NSTEACS patients, respectively). The lowest bleeding rates observed in patients classified as low risk corresponded to the CRUSADE RS. All scores performed modestly in patients who did not undergo coronariography (all c-statistic <0.70). The CRUSADE score was significantly superior to the ACTION model in predicting the TIMI serious bleeding occurrence in terms of NRI overall and by ACS subgroups (p<0.05). Overall, the CRUSADE RS exhibited better calibration for predicting the TIMI serious bleeding compared to the ACTION and Mehran et al scores (Hosmer-Lemeshow p-values of 0.26, 0.13, and 0.07, respectively). Conclusion: The CRUSADE score represents, among the more contemporary bleeding RS, the most accurate and reliable quantitative clinical tool in STEACS and STEMI patients. We encourage the utilization of the CRUSADE index for bleeding risk stratification purposes in daily clinical practice and in ACS outcome studies. The performance of the three more contemporary bleeding RS is modest in those patients who received conservative management

Culture of Human Rotaviruses in Relevant Models Shows Differences in Culture-Adapted and Nonculture-Adapted Strains

Rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in children under 5 years old worldwide, and several studies have demonstrated that histo-blood group antigens (HBGAs) play a role in its infection process. In the present study, human stool filtrates from patients diagnosed with RV diarrhea (genotyped as P[8]) were used to infect differentiated Caco-2 cells (dCaco-2) to determine whether such viral strains of clinical origin had the ability to replicate in cell cultures displaying HBGAs. The cell culture-adapted human RV Wa model strain (P[8] genotype) was used as a control. A time-course analysis of infection was conducted in dCaco-2 at 1, 24, 48, 72, and 96 h. The replication of two selected clinical isolates and Wa was further assayed in MA104, undifferentiated Caco-2 (uCaco-2), HT29, and HT29-M6 cells, as well as in monolayers of differentiated human intestinal enteroids (HIEs). The results showed that the culture-adapted Wa strain replicated more efficiently in MA104 cells than other utilized cell types. In contrast, clinical virus isolates replicated more efficiently in dCaco-2 cells and HIEs. Furthermore, through surface plasmon resonance analysis of the interaction between the RV spike protein (VP8*) and its glycan receptor (the H antigen), the V7 RV clinical isolate showed 45 times better affinity compared to VP8* from the Wa strain. These findings support the hypothesis that the differences in virus tropism between clinical virus isolates and RV Wa could be a consequence of the different HBGA contents on the surface of the cell lines employed. dCaco-2, HT29, and HT29M6 cells and HIEs display HBGAs on their surfaces, whereas MA104 and uCaco-2 cells do not. These results indicate the relevance of using non-cell culture-adapted human RV to investigate the replication of rotavirus in relevant infection models.This research was funded by the Spanish Ministry of Science and Innovation (MICIN)/Spanish State Research Agency (AEI)/10.13039/501100011033 Project grants PID2020-115403RB C21 to M.J.Y. and PID2020-115403RB C22 to J.R.-D. This study was also supported by the Valencian Government grant CIAICO/2022/033 to J.R.-D. N.P.-G. is the recipient of a predoctoral grant from the Valencian Government (ACIF/2020/085). C.S.-B. is the recipient of an FPI predoctoral grant PRE2018-083315 from MICIN/AEI/10.13039/501100011033 and “ESF Investing in your future”. N.N.-L. is the recipient of a predoctoral grant from the Valencian Government (ACIF/2020/076). R.C.-C. is the recipient of a predoctoral grant from the Valencian Government (ACIF/2021/162). This study was supported by PREVISION project (reference no. PID2019-105509RJ-I00) funded by the Spanish Ministry of Science, Innovation, and Universities and AEI/FEDER, UE to W.R.With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX 2021-001189-S)Peer reviewe

Follow-up of gone away in the accreditation of Master in Infirmary of the BUAP

[EN] Introduction: The follow-up of gone away is an indicator of the relevancy of the Study plan, in case of the Master in Infirmary it is a source of information for the modification of the programs of the subjects as well as the identification of the needs of education continues of the gone away ones. Aims To identify the opinion of the gone away ones from the study plan, that course, requirements of the labor market, professional performance and needs of update. Methodology: Type of study: descriptive, longitudinal. Results: They met 1120egresados, 65 % of the gone away ones obtained employment to six months of concluding the career, the principal activity that they realize is the care of patients, 59 % thinks that the labor coincidence is total with his studies, the economic sector at which they are employed is that of services of health. He thinks that the content of the programs of the subjects as well as the knowledge of the teachers as good, 86. % would return to study the master in infirmary. Conclusion: the opinion of the gone away ones has allowed the extension of the practices, the implementation of the programs of the specialities of infirmary and that the program of the master continues being an educational program of quality when assessors are accredited by the organisms as COMACE CIEES[ES] Introducción: El seguimiento de egresados es un indicador de la pertinencia del Plan de Estudios, en el caso de la Licenciatura en Enfermería es fuente de información para la modificación de los programas de las asignaturas así como la identificación de las necesidades de educación continua de los egresados.Objetivos: Identificar la opinión de los egresados del plan de estudios, que curso, exigencias del mercado laboral, desempeño profesional y necesidades de actualización.Metodología: Tipos de estudio: descriptivo, longitudinal.Resultados: Se entrevistaron 1120egresados, el 65% de los egresados obtuvieron empleo a los seis meses de concluir la carrera, la principal actividad que realizan es el cuidado de pacientes, el 59% opina que es total la coincidencia laboral con sus estudios, el sector económico en el que trabajan es el de servicios de salud. Opina que el contenido de los programas de las asignaturas así como los conocimientos de los docentes como buenos, el 86 % volvería estudiar la licenciatura en enfermería.Conclusión: la opinión de los egresados ha permitido la ampliación de las practicas, la implementación de los programas de las especialidades de enfermería y que el programa de la licenciatura siga siendo un programa educativo de calidad al ser acreditado por los organismos evaluadores como COMACE CIFRUS.Salazar Peña, MTL.; Trujillo De La Cruz, C.; Perez Noriega, E.; Bonilla Luis, MDLL.; Rios Palacios, N.; Morales Espinoza, MDL.; Huesca Gil, JLA. (2014). Seguimiento de egresados en la acreditación de Licenciatura en Enfermeria de la BUAP. En CONFERENCIA INTERNACIONAL INFOACES. UN SISTEMA DE INFORMACIÓN PARA LAS UNIVERSIDADES LATINOAMERICANAS. LIBRO DE ACTAS. Editorial Universitat Politècnica de València. 83-86. http://hdl.handle.net/10251/85894OCS838

Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy:Study protocol of a cluster randomized clinical trial (Multi-PAP project)

This study was funded by the Fondo de Investigaciones Sanitarias ISCIII (Grant Numbers PI15/00276, PI15/00572, PI15/00996), REDISSEC (Project Numbers RD12/0001/0012, RD16/0001/0005), and the European Regional Development Fund ("A way to build Europe").Background: Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12months, as compared with usual care. Methods/Design: Design:pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. Scope: PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). Population: patients aged 65-74years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3months). Sample size: n=400 (200 per study arm). Intervention: complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. Outcomes: MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. Statistical analysis: primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. Discussion: It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Trial registration: Clinicaltrials.gov, NCT02866799Publisher PDFPeer reviewe