70 research outputs found
Marine Citizen Science: Current State in Europe and New Technological Developments
Marine citizen science is emerging with promising opportunities for science, policy and
public but there is still no comprehensive overview of the current state in Europe.
Based on 127 projects identified for the North Sea area we estimate there might be
as much as 500 marine and coastal citizen science projects running in Europe, i.e.,
one marine citizen science project per 85 km of coastline, with an exponential growth
since 1990. Beach-based projects are more accessible and hence most popular (60%
of the projects), and the mean duration of the projects is 18–20 years. Current trends,
topics, organizers, aims, and types of programme in terms of participation are presented
in this overview. Progress in marine citizen science is specially enabled and promoted
through technological developments. Recent technological advances and best practise
examples are provided here, untapping the potential of smart mobile apps, do-it-yourself
(DIY) technologies, drones, and artificial intelligence (AI) web servicesVersión del edito
Strong fisheries management and governance positively impact ecosystem status
Bundy, Alida ... et al.-- 28 pages, 6 figures, 8 tables, supporting information https://dx.doi.org/10.1111/faf.12184Fisheries have had major negative impacts on marine ecosystems, and effective fisheries management and governance are needed to achieve sustainable fisheries, biodiversity conservation goals and thus good ecosystem status. To date, the IndiSeas programme (Indicators for the Seas) has focussed on assessing the ecological impacts of fishing at the ecosystem scale using ecological indicators. Here, we explore fisheries ‘Management Effectiveness’ and ‘Governance Quality’ and relate this to ecosystem health and status. We developed a dedicated expert survey, focused at the ecosystem level, with a series of questions addressing aspects of management and governance, from an ecosystem-based perspective, using objective and evidence-based criteria. The survey was completed by ecosystem experts (managers and scientists) and results analysed using ranking and multivariate methods. Results were further examined for selected ecosystems, using expert knowledge, to explore the overall findings in greater depth. Higher scores for ‘Management Effectiveness’ and ‘Governance Quality’ were significantly and positively related to ecosystems with better ecological status. Key factors that point to success in delivering fisheries and conservation objectives were as follows: the use of reference points for management, frequent review of stock assessments, whether Illegal, Unreported and Unregulated (IUU) catches were being accounted for and addressed, and the inclusion of stakeholders. Additionally, we found that the implementation of a long-term management plan, including economic and social dimensions of fisheries in exploited ecosystems, was a key factor in successful, sustainable fisheries management. Our results support the thesis that good ecosystem-based management and governance, sustainable fisheries and healthy ecosystems go togetherThis is a contribution to the IndiSeas Working Group, which, by the time of the study, was cofunded by IOC-UNESCO (www.ioc-unesco.org), EuroMarine (http://www.euromarinenetwork.eu), the European FP7 MEECE research project, the European Network of Excellence Eur-Oceans and the FRB EMIBIOS project (contract n°212085)Peer Reviewe
Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer
BACKGROUND: It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and destruction of their tumors. Thus, an important goal for tumor immunotherapy is to identify ways to modulate in vivo anti-tumor immunity to achieve clinical efficacy. We investigate this proposition in a spontaneous mouse tumor model, Rip1-Tag2. METHODS: Experimental therapies were carried out in two distinctive trial designs, intended to either intervene in the explosive growth of small tumors, or regress bulky end-stage tumors. Rip1-Tag2 mice received a single transfer of splenocytes from Tag-specific, CD4(+) T cell receptor transgenic mice, a single sub-lethal radiation, or a combination therapy in which the lymphocyte transfer was preceded by the sub-lethal radiation. Tumor burden, the extent of lymphocyte infiltration into solid tumors and host survival were used to assess the efficacy of these therapeutic approaches. RESULTS: In either intervention or regression, the transfer of Tag-specific T cells alone did not result in significant lymphocyte infiltration into solid tumors, not did it affect tumor growth or host survival. In contrast, the combination therapy resulted in significant reduction in tumor burden, increase in lymphocyte infiltration into solid tumors, and extension of survival. CONCLUSIONS: The results indicate that certain types of solid tumors may be intrinsically resistant to infiltration and destruction by tumor-specific T lymphocytes. Our data suggest that such resistance can be disrupted by sub-lethal radiation. The combinatorial approach presented here merits consideration in the design of clinical trials aimed to achieve T cell-mediated anti-tumor immunity
The Nature Index: A General Framework for Synthesizing Knowledge on the State of Biodiversity
The magnitude and urgency of the biodiversity crisis is widely recognized within
scientific and political organizations. However, a lack of integrated measures
for biodiversity has greatly constrained the national and international response
to the biodiversity crisis. Thus, integrated biodiversity indexes will greatly
facilitate information transfer from science toward other areas of human
society. The Nature Index framework samples scientific information on
biodiversity from a variety of sources, synthesizes this information, and then
transmits it in a simplified form to environmental managers, policymakers, and
the public. The Nature Index optimizes information use by incorporating expert
judgment, monitoring-based estimates, and model-based estimates. The index
relies on a network of scientific experts, each of whom is responsible for one
or more biodiversity indicators. The resulting set of indicators is supposed to
represent the best available knowledge on the state of biodiversity and
ecosystems in any given area. The value of each indicator is scaled relative to
a reference state, i.e., a predicted value assessed by each expert for a
hypothetical undisturbed or sustainably managed ecosystem. Scaled indicator
values can be aggregated or disaggregated over different axes representing
spatiotemporal dimensions or thematic groups. A range of scaling models can be
applied to allow for different ways of interpreting the reference states, e.g.,
optimal situations or minimum sustainable levels. Statistical testing for
differences in space or time can be implemented using Monte-Carlo simulations.
This study presents the Nature Index framework and details its implementation in
Norway. The results suggest that the framework is a functional, efficient, and
pragmatic approach for gathering and synthesizing scientific knowledge on the
state of biodiversity in any marine or terrestrial ecosystem and has general
applicability worldwide
Fate and effects of nanoparticles in aquatic ecotoxicity tests
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