Bajo Tierra

La obra fue realizada en el año 2017 como trabajo final de la cátedra Teoría de la Práctica Artística, por seis estudiantes de la Facultad de Bellas Artes, de cinco disciplinas diferentes: Plástica, Escenografía, Multimedia, Artes Audiovisuales y Música. La obra se titula “Bajo tierra” como metáfora de lo que sucede en los talleres que conforman el histórico establecimiento, que justamente se sitúan en los subsuelos del Teatro. El audiovisual consiste en un recorrido continuo, mediante plano secuencia (con la técnica hiperlapse), por cada uno de esos talleres. Haciendo especial énfasis en la cartelería utilizada por los trabajadores (vestuaristas, zapateros, peluqueros, maquilladores, escenógrafos, carpinteros y escultores) como parte de su reclamo. De esta manera, la música y la imagen confluyen creando una atmósfera punzante en su devenir temporal que potencia la significación de los espacios transitados.Facultad de Bellas Arte

Bajo Tierra

La obra fue realizada en el año 2017 como trabajo final de la cátedra Teoría de la Práctica Artística, por seis estudiantes de la Facultad de Bellas Artes, de cinco disciplinas diferentes: Plástica, Escenografía, Multimedia, Artes Audiovisuales y Música. La obra se titula “Bajo tierra” como metáfora de lo que sucede en los talleres que conforman el histórico establecimiento, que justamente se sitúan en los subsuelos del Teatro. El audiovisual consiste en un recorrido continuo, mediante plano secuencia (con la técnica hiperlapse), por cada uno de esos talleres. Haciendo especial énfasis en la cartelería utilizada por los trabajadores (vestuaristas, zapateros, peluqueros, maquilladores, escenógrafos, carpinteros y escultores) como parte de su reclamo. De esta manera, la música y la imagen confluyen creando una atmósfera punzante en su devenir temporal que potencia la significación de los espacios transitados.Facultad de Bellas Arte

La música y la corporalidad: un recorrido hacia la consciencia corporal en el hacer musical

El presente trabajo pretende mostrar que existen diferentes tipos de relaciones entre cuerpo y música, que variarán dependiendo del tipo de formación que se haya transitado, del instrumento elegido, del repertorio y de la conciencia corporal. A su vez estos aspectos se analizaran teniendo en cuenta la clase social de las y los músicos valiéndonos de los concepto abordados por García Canclini tomados de Pierre Bourdieu.Facultad de Bellas Arte

La música y la corporalidad: un recorrido hacia la consciencia corporal en el hacer musical

El presente trabajo pretende mostrar que existen diferentes tipos de relaciones entre cuerpo y música, que variarán dependiendo del tipo de formación que se haya transitado, del instrumento elegido, del repertorio y de la conciencia corporal. A su vez estos aspectos se analizaran teniendo en cuenta la clase social de las y los músicos valiéndonos de los concepto abordados por García Canclini tomados de Pierre Bourdieu.Facultad de Bellas Arte

La música y la corporalidad: un recorrido hacia la consciencia corporal en el hacer musical

El presente trabajo pretende mostrar que existen diferentes tipos de relaciones entre cuerpo y música, que variarán dependiendo del tipo de formación que se haya transitado, del instrumento elegido, del repertorio y de la conciencia corporal. A su vez estos aspectos se analizaran teniendo en cuenta la clase social de las y los músicos valiéndonos de los concepto abordados por García Canclini tomados de Pierre Bourdieu.Facultad de Bellas Arte

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P <0.01) and previous renal failure (57.9%, P <0.01). Patients treated with cloxacillin presented higher rates of septic shock (25%, P = 0.033) and new-onset or worsening renal failure (47.3%, P = 0.024) with significantly higher rates of in-hospital mortality (38.5%, P = 0.017). One-year IE-related mortality and rate of relapses were similar between treatment groups. None of the treatments were identified as risk or protective factors. Conclusion: Our results suggest that cefazolin is a valuable option for the treatment of MSSA IE, without differences in 1-year mortality or relapses compared with cloxacillin, and might be considered equally effective