Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Forecasting yearly geomagnetic variation through sequential estimation of core low and magnetic diffusion

Earth’s internal magnetic field is generated through motion of the electrically conductive iron-alloy fluid comprising its outer core. Temporal variability of this magnetic field, termed secular variation (SV), results from two processes: one is the interaction between core fluid motion and the magnetic field, the other is magnetic diffusion. As diffusion is widely thought to take place over relatively long, millennial time scales, it is common to disregard it when considering yearly to decadal field changes; in this frozen-flux approximation, core fluid motion may be inferred on the core–mantle boundary (CMB) using observations of SV at Earth’s surface. Such flow models have been used to forecast variation in the magnetic field. However, recent work suggests that diffusion may also contribute significantly to SV on short time scales provided that the radial length scale of the magnetic field structure within the core is sufficiently short. In this work, we introduce a hybrid method to forecast field evolution that considers a model based on both a steady flow and diffusion, in which we adopt a two-step process: first fitting the SV to a steady flow, and then fitting the residual by magnetic diffusion. We assess this approach by hindcasting the evolution for 2010–2015, based on fitting the models to CHAOS-6 using time windows prior to 2010. We find that including diffusion yields a reduction of up to 25% in the global hindcast error at Earth’s surface; at the CMB this error reduction can be in excess of 77%. We show that fitting the model over the shortest window that we consider, 2009–2010, yields the lowest hindcast error. Based on our hindcast tests, we present a candidate model for the SV over 2020–2025 for IGRF-13, fit over the time window 2018.3–2019.3. Our forecasts indicate that over the next decade the axial dipole will continue to decay, reversed-flux patches will increase in both area and intensity, and the north magnetic (dip) pole will continue to migrate towards Siberia

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Continuous millennial decrease of the earth's magnetic axial dipole

FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOSince the establishment of direct estimations of the Earth's magnetic field intensity in the first half of the nineteenth century, a continuous decay of the axial dipole component has been observed and variously speculated to be linked to an imminent reve2747286FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO2013/16382-0, NE/P00170X/1,2043/2014,454609/2014-0, 206997/2014-

Archaeointensity record of weak field recurrence in Japan: new data from Late Yayoi and Kofun ceramic artifacts

International audienceSummary We present new absolute archaeointensity data from six archaeological sites situated in the Okayama Prefecture, Japan. The materials studied are well-dated fragments from pottery, ceramic coffins and haniwa artifacts. Their ages range from 160 AD to 675 AD, covering the Late Yayoi and Kofun periods. Rock magnetic experiments suggest the presence of magnetite and/or Ti-magnetite as the main carrier of the remanence, with a possible minor contribution of higher coercivity minerals. After thermal demagnetization experiments, the most magnetically stable samples were selected for archaeointensity analysis performed following the double-heating method proposed by Thellier and modified by Coe. Partial thermoremanent magnetization (pTRM) checks and pTRM tail-checks were performed for monitoring possible chemical alterations during heating. All measurements were corrected for both anisotropy and cooling-rate effects. Successful archaeointensity determinations, following rigorous selection criteria, were obtained for samples from all the investigated archaeological sites. Compared with literature data from Japan, the new high-quality data show significantly lower intensity values. They also reveal possible fast secular variation changes during the Late Yayoi period and very weak geomagnetic intensity field around 630 AD. Such values offer evidence of a possible recurrence of weak intensity field in East Asia, suggesting an ancient recurrence of the West Pacific Anomaly. The new data might change the archaeomagnetic field models interpretations in the area, even though more data are still necessary to better understand the secular variation in Japan and the temporal evolution of the geomagnetic field's behavior in East Asia.</jats:p

Paleosecular Variation and the Time-Averaged Geomagnetic Field Since 10 Ma

International audienc

Caracterização fenológica e requerimento térmico da cultivar moscato giallo sob cobertura plástica Phenological characterization and thermal requirement of moscato giallo cultivar under plastic cover

Os efeitos da cobertura plástica (CP) sobre a fenologia e o requerimento térmico da Vitis vinifera L. 'Moscato Giallo' foram estudados em dois ciclos (2005/2006 e 2006/2007). Determinou-se a duração média dos principais períodos fenológicos por meio de avaliações semanais, desde a poda até a queda das folhas. O somatório térmico em graus-dia acumulados (GD) foi calculado considerando-se a temperatura-base de 10ºC, e medidas da temperatura do ar máxima e mínima ao longo de todo o ciclo, nas áreas coberta e descoberta (testemunha). A cobertura plástica aumentou o somatório térmico e antecipou o início da brotação, reduzindo a duração das etapas fenológicas da poda até a mudança de cor das bagas. Entretanto, a redução da radiação fotossinteticamente ativa (RFA) proporcionada pela cobertura plástica atrasou, em média, 18 dias o processo de maturação das uvas da cultivar Moscato Giallo. A soma térmica acumulada (poda até colheita) das áreas coberta e descoberta foi, respectivamente, 2.079 e 1.847 GD no primeiro ciclo, e 1.864 e 1.640 GD no segundo ciclo. A cobertura plástica exige uma alteração nas práticas culturais, como a necessidade de poda verde para reduzir os efeitos da restrição de RFA e o atraso na data de colheita, em relação ao cultivo convencional, em função da menor taxa de evolução da maturação sob a cobertura.<br>The plastic overhead cover (POC) effects on phenology and thermal requirement of grapevine Vitis vinifera L. 'Moscato Giallo' were evaluated in two seasons (2005/2006 and 2006/2007). The phenology was weekly determined since the winter pruning until the falling of the leaves. The thermal requirement as degree-days (GDºC) was calculated in the same period using 10ºC as base temperature and measured of maximal and minimal air temperature throughout both cycles in covered and uncovered areas. POC increased the thermal sum and it anticipated the budburst and decreased the duration of phenological phases from the winter pruning until the changing of the colors of the berries. However, the POC restricted the photosynthetically active radiation (PAR) and it reduced in 18 days the ripening process of grapes, in relation to uncovered plants. The thermal sum accumulated (pruning to harvest) under covered and uncovered areas was respectively, 2079 and 1864 GDºC in the first cycle, and 1847 and 1640 GDºC in the second cycle. POC demands alterations in vineyard management such as the green pruning (aiming to reduce the effect of PAR restriction) and the delay in harvest date due to lower ripening under POC, in comparison to uncovered cultivation