Influence of aerobic physical training in the motochondrial transport of long chain fatty acids in the skeletal muscle: role of the carnitine palmitoil transferase

O ácido graxo (AG) é uma importante fonte de energia para o músculo esquelético. Durante o exercício sua mobilização é aumentada para suprir as necessidades da musculatura ativa. Acredita-se que diversos pontos de regulação atuem no controle da oxidação dos AG, sendo o principal a atividade do complexo carnitina palmitoil transferase (CPT), entre os quais três componentes estão envolvidos: a CPT I, a CPT II e carnitina acilcarnitina translocase. A função da CPT I durante o exercício físico é controlar a entrada de AG para o interior da mitocôndria, para posterior oxidação do AG e produção de energia. Em resposta ao treinamento físico há um aumento na atividade e expressão da CPT I no músculo esquelético. Devido sua grande importância no metabolismo de lipídios, os mecanismos que controlam sua atividade e sua expressão gênica são revisados no presente estudo. Reguladores da expressão gênica de proteínas envolvidas no metabolismo de lipídios no músculo esquelético, os receptores ativados por proliferadores de peroxissomas (PPAR) alfa e beta, são discutidos com um enfoque na resposta ao treinamento físico.Fatty acids are an important source of energy for the skeletal muscle. During exercise, their mobilization is increased to supply the muscle energetic needs. Many points of regulation act in the fatty acids metabolism, where the carnitine palmytoiltransferase (CPT) complex is the main control system. Three compounds named CPT I, CPT II and carnitine acyl carnitine translocase (CACT) are components of this system. Its function is to control the influx of fatty acids inside the mitochondria for posterior oxidation and energy production. There is a pronounced increase in both activity and gene expression of CPT I in the skeletal muscle in response to exercise. Due to its importance in lipid metabolism, the controlling mechanisms are reviewed in the present study. The modulation of gene expression by peroxisome proliferator-activated receptors (PPARs) alpha and beta during the physical training is also discussed in this review

Dinâmica espacial de lagoas marginais presentes no rio Aiuruoca, MG, em períodos de cheia e seca

Floodplains are lands periodically covered with water when rivers overflow their banks. In the tropics, a large portion of fish communities uses the floodplains as habitats for feeding, reproduction, and refuge. For this reason, these habitats are priority for fish conservation and management. The present work aims to analyze the classification resulting from object-based method of floodplains, estimating the connectivity with Aiuruoca river. The study required 2 images of Landsat TM sensor, with 30 meters of spatial resolution all obtained in 2001. Given its efficiency to detect floodplain changes and its automated character, this method seems to constitute an operational tool adequate for floodplain monitoring. Lagoas marginais são utilizadas por comunidades de peixes como habitat, alimentação, reprodução e refúgio. Por esta razão estes ambientes são considerados prioritários à conservação e manejos. O presente estudo objetivou realizar a classificação orientada a objeto no intuito de localizar as lagoas marginais presentes no entorno do rio Aiuruoca, identificando a conexão destas ao rio em períodos de cheia e seca. Utilizou-se duas imagens Landsat 5TM, com 30 metros de resolução espacial do ano 2001, representativas do período de cheia e seca, com uma área de estudo de 3.342 km2. A classificação resultou em valores de precisão global variando de 98,9% para a época de cheia e em 98,8% para a época de seca, e de 63% e 52% de precisão pelo índice de Kappa para épocas de cheia e seca, respectivamente. Os resultados indicaram alterações no número, área e na conectividade de  lagoas marginais para os períodos de chuva e seca. Este método se mostrou bastante adequado na identificação de lagoas marginais e possui grande importância no monitoramento das alterações dos ciclos a que estes ambientes estão submetidos, possibilitando o estudo da dinâmica e a possibilidade de utilização no monitoramento e gestão destes ambientes

Soil preparation and NPK fertilization in the planting of five Atlantic Rainforest species in a clay extraction area

The occurrence of degraded areas worldwide grows each year and measures must be taken to mitigate degradation and to recover these areas. The aim of this study was to assess the effect of soil preparation and NPK levels on the growth of five native species of the Atlantic Rainforest in clay extraction area. The experimental design was randomized block in a split-split plot arrangement with four replications. Subsoiling and scarification soil preparation represented main plots.  Doses of NPK 04-14-08: 0; 40; 80;160; and 320 g pit-1 represented subplots and Atlantic Rainforest native species represented sub-subplots. Absolute growth rate, stem diameter and number of leaves were evaluated, 210 days after planting. The type of soil preparation did not influence the development of the species. The best dose for Dalbergia ecastaphyllum, Inga laurina, Protium heptaphyllum and Psidium cattleyanum were 176.49, 150.18, 199.25 and 166.48 g pit-1 of NPK, respectively. Schinus terebinthifolius was highly responsive to planting fertilization, being recommended 320 g pit-1 of NPK. All species are indicated for area recovery.The occurrence of degraded areas worldwide grows each year and measures must be taken to mitigate degradation and to recover these areas. The aim of this study was to assess the effect of soil preparation and NPK levels on the growth of five native species of the Atlantic Rainforest in clay extraction area. The experimental design was randomized block in a split-split plot arrangement with four replications. Subsoiling and scarification soil preparation represented main plots.  Doses of NPK 04-14-08: 0; 40; 80;160; and 320 g pit-1 represented subplots and Atlantic Rainforest native species represented sub-subplots. Absolute growth rate, stem diameter and number of leaves were evaluated, 210 days after planting. The type of soil preparation did not influence the development of the species. The best dose for Dalbergia ecastaphyllum, Inga laurina, Protium heptaphyllum and Psidium cattleyanum were 176.49, 150.18, 199.25 and 166.48 g pit-1 of NPK, respectively. Schinus terebinthifolius was highly responsive to planting fertilization, being recommended 320 g pit-1 of NPK. All species are indicated for area recovery

SafeFollowing: A collaborative model for public security agents to assist people with disabilities and the elderly

In the last survey about the Brazilian population conducted by IBGE, more than 45.6 million of Brazilians declared that they have some kind of disability. Besides that, the same survey revealed that the number of elderly people has been increasing over the years and at that time it already represented 12.1 \% of the total. In this scenario, public policies that can efficiently ensure the rights of this share of the population became even more necessary. In the same manner, with the popularization of mobile devices, opportunities to develop new solutions are arising, offering more independence and quality of life to them. Ubiquitous accessibility support solutions have been proposed, such as the MASC model, which resorts to the concept of smart assistive city; and more recently the AccompCare, which predicts the monitoring of people with disabilities and the elderly. This article proposes the SafeFollowing, a model that enables integrated and collaborative acting of the community aiming to assist people with some kind of disability or elderly people. The SafeFollowing predicts the use of police cars mapping, in order to provide a specific follow-up in adverse daily situations. The validation of the model is also presented in the article, which was performed through experiments in real test scenarios

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio