841 research outputs found
Expertise in Law Enforcement
Book Chapte
Collier Heights
This resource was created by the Case Studies class in Spring of 2008 as a Historic District Information Form. It includes data on the neighborhood known as Collier Heights, as well as pertinent newspaper clippings, permits, blueprints, maps, and other primary sources.https://scholarworks.gsu.edu/history_heritagepreservation/1011/thumbnail.jp
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NO SPACE LEFT BEHIND - Graduate Urban Design Studio - LANDARCH 606
The following report documents the work of the 2015 Spring Graduate Urban Design Studio course in the Department of Landscape Architecture and Regional Planning. This fourteen week studio focused on using tactical urbanism to engage Springfieldâs Metro Center neighborhood with visions to revitalize the downtown core of this legacy city.
In addition to completing the components of a traditional urban design studio (site analyses, schematic plans, spatial designs, and programming), the student teams also developed conceptual projects to immediately engage the public. These efforts culminated in a free afternoon walking tour throughout the Metro Center that presented several tactical interventions. These interactive, public installations illustrated potential future initiatives and brought attention to overlooked areas and assets. Throughout the semester the teams were challenged to continuously consider both the short-term impacts of their interventions and the long-term visions for the future of Springfieldâs urban core. This strategy allowed students to develop a process-based approach to urban design. It provided opportunities to engage stakeholders and test new ideas with the public, rather than simply creating a master plan without any real world interactions with the city and its populace.
STUDIO GOALS
âą To enliven public space in Springfieldâs Metro Center through small-scale urban design interventions which illustrate and inform long-term plans
âą To activate residual spaces in the downtown with Tactical Urbanism
By matching long-term visions for the Metro Center with short-term, site-specific tactical interventions the teams were able to deliver a variety of ideas in multiple formats. Furthermore, the experience of interacting with community members during the installation of projects added a great deal of meaning to the research and design process.
The work explores a community service learning strategy within the framework of an urban design studio with the goal of revitalizing the city of Springfield, Massachusetts, through sustainable design, planning, and engagement with the community.
The six design-team interventions are documented and published as team-authored videos:
1. Union Station Green Corridor
Maozhu Mao, Yuqing Wu
https://www.youtube.com/watch?v=EnE8Yt8x0Es&feature=youtu.be
2. (No) Vacancy
Chris Counihan, Michalagh Stoddard, Ruoying Tang
https://youtu.be/CapaQ9gDxeM
3. Extra Space, Active Street
Yu Yu
https://youtu.be/2pgYq5HLNHA
4. Spring into Art
Emilie Jordao, Matt Hisle, Jing Wang
https://youtu.be/Vf2yk6Se6rU
5. Urban Agua
Kellie Fenton, James Prendergast, Nelle Ward
https://www.youtube.com/watch?v=vk2PUJMdhTU&feature=youtu.be
6. Make the Connection
Yue Li, Yanhua Lu, Yi Yang
https://youtu.be/EvQD0QYV97
Effect of amlodipine on the circulating renin-angiotensin-aldosterone system in healthy cats
Background: Systemic hypertension (SH) is a common cardiovascular disease in older cats that is treated primarily with the calcium channel blocker amlodipine besylate (AML). The systemic effect of AML on the classical and alterative arms of the renin-angiotensin-aldosterone system (RAAS) in cats is incompletely characterized.Hypothesis/Objectives: To determine the effect of AML compared to placebo on circulating RAAS biomarkers in healthy cats using RAAS fingerprinting. Animals: Twenty healthy client-owned cats. Methods: Cats were administered amlodipine besylate (0.625âmg in toto) or placebo by mouth once daily for 14âdays in a crossover design with a 4-week washout period. Plasma AML concentrations and RAAS biomarker concentrations were measured at multiple timepoints after the final dose in each treatment period. Time-weighted averages for RAAS biomarkers over 24âhours after dosing were compared between treatment groups using Wilcoxon rank-sum testing. Results: Compared to placebo, AML treatment was associated with increases in markers of plasma renin concentration (median 44% increase; interquartile range [IQR] 19%-86%; Pâ=â.009), angiotensin I (59% increase; IQR 27-101%; Pâ=â.006), angiotensin II (56% increase; IQR 5-70%; Pâ=â.023), angiotensin IV (42% increase; â19% to 89%; Pâ=â.013); and angiotensin 1-7 (38% increase; IQR 9-118%; Pâ=â.015). Conclusions and Clinical Importance: In healthy cats, administration of AML resulted in nonspecific activation of both classical and alternative RAAS pathways.This article is published as Garcia Marrero, Tatiana M., Jessica L. Ward, Melissa A. Tropf, Agnes BourgoisâMochel, Emilie Guillot, Oliver Domenig, Lingnan Yuan, Debosmita Kundu, and Jonathan P. Mochel. "Effect of amlodipine on the circulating reninâangiotensinâaldosterone system in healthy cats." Journal of Veterinary Internal Medicine (2024). doi: https://doi.org/10.1111/jvim.17006. © 2024 The Authors. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs
From Expert Administration to Accountability Network: A New Paradigm for Comparative Administrative Law
Notwithstanding the radically changed landscape of contemporary administrative governance, the categories that guide comparative administrative law and that determine what will be compared remain similar to those used at the founding of the discipline in the late 1800s. These categories are rooted in confidence in an expert bureaucracy to accomplish public purposes and are mainly twofold - administrative organization and judicial review. This outdated model has limited the ability of comparative law to engage with contemporary debates on the administrative state, which instead display considerable skepticism of public administration and are premised on achieving the public good through a plural accountability network of public and private actors. This Article seeks to correct the anachronism by reframing comparative administrative law as an accountability network of rules and procedures designed to embed public administration and civil servants in their liberal democratic societies: accountability to elected officials, organized interests, the courts, and the general public. Based on this paradigm, the Article compares American and European administrative law in a global context. Among the many differences explored are parliamentary versus presidential political control, pluralist versus neo-corporatist forms of self-regulation and public-private collaboration, judicial review focused on fundamental rights versus policy rationality, and reliance on ombudsmen in lieu of courts. The Article concludes with a number of suggestions for how comparative law can speak to current debates on reforming administrative governance
Starting Day Care in Espoo from the Viewpoint of Chinese Parents
The thesis is a small-scale evaluative research. The day care start folder, which provided practical and detailed information about starting Finnish day care to support multicultural parents in Otaniemi day-care centre and Servin-Maija day-care centre, was assessed among nine Chinese parents of children in five municipal and outsourced day-care centres in the City of Espoo.
The purposes of the current research were to find out how Chinese parents perceive starting day care in the City of Espoo and their difficulties and suggestions concerning starting day care in the City of Espoo; to evaluate how the day care start folder is experienced as a working method in opinion of Chinese parents living in the City of Espoo; and to further improve the day care start folder as a working method for multicultural families and personnel in Otaniemi day-care centre and possibly for other day-care centres in the similar situation.
Two types of interview, namely semi-structured individual interview and focus group interview, were utilised as the primary qualitative data-collecting methods in the current research. In addition, questionnaire as an assistant quantitative data-collecting method was employed as well to ensure verification of the consistency of the data, and supplement the abundance of the narrative data collected from interviews.
The qualitative data gathered from the six interviews was coded, categorised and analysed in accordance with the method of content analysis. The results showed that the participating Chinese parents basically concerned about the information on starting day care; their childâs language learning; their communication and cooperation with day-care staff; cultures, religions and festivals; playing, learning and friends; child protection and legislation and so forth.
Furthermore, these Chinese parents also put forward some important problems and suggestions on Finnish day care, such as problems caused by cultural differences, different opinions on learning by playing and Finnish as a second language-teaching, difficulties to obtain enough English information about Finnish day care, and the lack of mediums for foreign families to receive help concerning Finnish day care. In addition, these Chinese parents perceived the day care start folder as useful and adequate. The results based on the questionnaires supported and verified the results generated from the qualitative data analysis
Reconstructing the Deep Population History of Central and South America
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least 9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central Andes by 4,200 years ago, while the other explains an affinity between the oldest North American genome associated with the Clovis culture and the oldest Central and South Americans from Chile, Brazil, and Belize. However, this was not the primary source for later South Americans, as the other ancient individuals derive from lineages without specific affinity to the Clovis-associated genome, suggesting a population replacement that began at least 9,000 years ago and was followed by substantial population continuity in multiple regions
Methylobacterium Genome Sequences: A Reference Blueprint to Investigate Microbial Metabolism of C1 Compounds from Natural and Industrial Sources
Methylotrophy describes the ability of organisms to grow on reduced organic compounds without carbon-carbon bonds. The genomes of two pink-pigmented facultative methylotrophic bacteria of the Alpha-proteobacterial genus Methylobacterium, the reference species Methylobacterium extorquens strain AM1 and the dichloromethane-degrading strain DM4, were compared. Methodology/Principal Findings The 6.88 Mb genome of strain AM1 comprises a 5.51 Mb chromosome, a 1.26 Mb megaplasmid and three plasmids, while the 6.12 Mb genome of strain DM4 features a 5.94 Mb chromosome and two plasmids. The chromosomes are highly syntenic and share a large majority of genes, while plasmids are mostly strain-specific, with the exception of a 130 kb region of the strain AM1 megaplasmid which is syntenic to a chromosomal region of strain DM4. Both genomes contain large sets of insertion elements, many of them strain-specific, suggesting an important potential for genomic plasticity. Most of the genomic determinants associated with methylotrophy are nearly identical, with two exceptions that illustrate the metabolic and genomic versatility of Methylobacterium. A 126 kb dichloromethane utilization (dcm) gene cluster is essential for the ability of strain DM4 to use DCM as the sole carbon and energy source for growth and is unique to strain DM4. The methylamine utilization (mau) gene cluster is only found in strain AM1, indicating that strain DM4 employs an alternative system for growth with methylamine. The dcm and mau clusters represent two of the chromosomal genomic islands (AM1: 28; DM4: 17) that were defined. The mau cluster is flanked by mobile elements, but the dcm cluster disrupts a gene annotated as chelatase and for which we propose the name âisland integration determinantâ (iid).Conclusion/Significance These two genome sequences provide a platform for intra- and interspecies genomic comparisons in the genus Methylobacterium, and for investigations of the adaptive mechanisms which allow bacterial lineages to acquire methylotrophic lifestyles.Organismic and Evolutionary Biolog
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