162 research outputs found

    Performance Enhancement of Multiuser Time Reversal UWB Communication System

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    UWB communication is a recent research area for indoor propagation channels. Time Reversal (TR) communication in UWB has shown promising results for improving the system performance. In multiuser environment, the system performance is significantly degraded due to the interference among different users. TR reduces the interference caused by multiusers due to its spatial focusing property. The performance of a multiuser TR communication system is further improved if the TR filter is modified. In this paper, multiuser TR in UWB communication is investigated using simple TR filter and a modified TR filter with circular shift operation. The concept of circular shift in TR is analytically studied. Thereafter, the channel impulse responses (CIR) of a typical indoor laboratory environment are measured. The measured CIRs are used to analyze the received signal peak power and signal to interference ratio (SIR) with and without performing the circular shift operation in a multiuser environment

    Multiuser Time Reversal UWB Communication System: A Modified Transmission Approach

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    International audienceIn this paper, ultra-wideband (UWB), time reversal (TR) communication is investigated by modifying the transmission prefilter. Mathematical expressions for received signal and the interference in the modified transmission scheme are derived. It is shown that the modified transmission approach reduces multi-user interference which eventually translates into a better bit error rate (BER) performance than simple TR multiuser scheme. Channel impulse responses (CIR) of a typical indoor channel are measured. In a multi-user scenario, both TR and the modified TR schemes are studied using the measured CIRs. It is shown that the proposed modified TR scheme outperforms the original TR scheme

    Simulation Analysis of Wireless Channel Effect on IEEE 802.11n Physical Layer

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    International audienceIEEE 802.11n standard came as a rescue; the existing standards are increasingly seen as inadequate since applications become more complex and require more bandwidth. Several techniques have been put into operation to meet two basic requirements: significantly greater bit rate and radio coverage. However, studies have shown that the theoretical limit in terms of throughput is far from being reached and that the received power does not explain the performance degradation. A list of suspect parameters is analyzed in this paper to assess their effect on performance of the IEEE 802.11n physical layer taken as an application of MIMO technology in indoor context. It is shown that for values of angular spread below 27°, the data rate cannot exceed 117 Mbps and the antennas spacing can compensate the performance degradation caused by other parameters. Results are given in terms of correlation coefficient, other channel characteristics and the packet error rate

    Nouvelle technique d'identification des caractéristiques spatio-temporelles d’un canal de propagation

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    National audienceL'émergence de la technologie MIMO requiert des modélisations de canal de transmission de plus en plus avancées. L’approche la plus aboutie représente le canal par un ensemble de trajets respectant les propriétés spatio-temporelles. Toutefois, la véritable difficulté réside dans la complexité des algorithmes d’estimation des paramètres. Nous introduisons dans cet article une méthode à la fois simple et rapide pour estimer conjointement à l’émetteur et au récepteur les composantes déterministes du canal de propagation. L’algorithme est évalué par des simulations et appliqué à des données expérimentales. L’apport de la prendre en compte de la composante diffuse est mise en évidence

    Restauración de caries oculta usando la técnica de réplica oclusal con matriz de acrílico

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    Eventualmente, las lesiones cariosas oclusales provocan un extenso compromiso del tejido dentinario, dejando prácticamente intacta la estructura del esmalte. Situación que debe ser corroborada radiográficamente y que representa la indicación ideal para utilizar la técnica de réplica de la anatomía oclusal. El objetivo del presente caso clínico fue describir los procedimientos del tratamiento restaurador mínimamente invasivo de lesiones de caries ocultas en las piezas dentarias 3.6 y 3.7 utilizando la técnica de la matriz de acrílico que registra la morfología oclusal pre-operatoria. Se logró copiar y reproducir fielmente tanto el color como la morfología oclusal original de las piezas dentarias restauradas. Se concluyó que la técnica con matriz de acrílico es una excelente alternativa de tratamiento que facilita la perfecta integración entre estética, función y conservación de los tejidos dentarios. También resulta costo efectiva, fácil de realizar y optimiza el tiempo de trabajo clínico

    Incidence and clinical outcomes of nosocomial infections in patients presenting with STEMI complicated by cardiogenic shock in the United States

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    OBJECTIVES: This study addresses the incidence, trends, and impact of nosocomial infections (NI) on the outcomes of patients admitted with ST-segment elevation myocardial infarction (STEMI) and cardiogenic shock (STEMI-CS) using the United States National Inpatient Sample (NIS) database. METHODS: We analyzed data from 105,184 STEMI-CS patients using the NIS database from the years 2005-2014. NI was defined as infections of more than or equal to three days, comprising of central line-associated bloodstream infection (CLABSI), urinary tract infection (UTI), hospital-acquired pneumonia (HAP), Clostridium difficile infection (CDI), bacteremia, and skin related infections. Outcomes of the impact of NI on STEMI-CS included in-hospital mortality, length of hospital stay (LOS) and costs. Significant associations of NI in patients admitted with STEMI-CS were also identified. RESULTS: Overall, 19.1% (20,137) of patients admitted with STEMI-CS developed NI. Trends of NI have decreased from 2005-2014. The most common NI were UTI (9.2%), followed by HAP (6.8%), CLABSI (1.5%), bacteremia (1.5%), skin related infections (1.5%), and CDI (1.3%). The strongest association of developing a NI was increasing LOS (7-9 days; OR: 1.99; 95% CI: 1.75-2.26; \u3e9 days; OR: 4.51; 95% CI: 4.04-5.04 compared to 4-6 days as reference). Increased mortality risk among patients with NI was significant, especially those with sepsis-associated NI compared to those without sepsis (OR: 2.95; 95% CI: 2.72-3.20). Patients with NI were found to be associated with significantly longer LOS and higher costs, irrespective of percutaneous mechanical circulatory support placement. CONCLUSIONS: NI were common among patients with STEMI-CS. Those who developed NI were at a greater risk of in-hospital mortality, increased LOS and costs

    Management of hepatitis C virus genotype 4: recommendations of an international expert panel.

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    HCV has been classified into no fewer than six major genotypes and a series of subtypes. Each HCV genotype is unique with respect to its nucleotide sequence, geographic distribution, and response to therapy. Genotypes 1, 2, and 3 are common throughout North America and Europe. HCV genotype 4 (HCV-4) is common in the Middle East and in Africa, where it is responsible for more than 80% of HCV infections. It has recently spread to several European countries. HCV-4 is considered a major cause of chronic hepatitis, cirrhosis, hepatocellular carcinoma, and liver transplantation in these regions. Although HCV-4 is the cause of approximately 20% of the 170 million cases of chronic hepatitis C in the world, it has not been the subject of widespread research. Therefore, this document, drafted by a panel of international experts, aimed to review current knowledge on the epidemiology, natural history, clinical, histological features, and treatment of HCV-4 infections

    Five Glutathione S-Transferase Gene Variants in 23,452 Cases of Lung Cancer and 30,397 Controls: Meta-Analysis of 130 Studies

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    BACKGROUND: Glutathione S-transferases (GSTs) are known to abolish or reduce the activities of intracellular enzymes that help detoxify environmental carcinogens, such as those found in tobacco smoke. It has been suggested that polymorphisms in the GST genes are risk factors for lung cancer, but a large number of studies have reported apparently conflicting results. METHODS AND FINDINGS: Literature-based meta-analysis was supplemented by tabular data from investigators of all relevant studies of five GST polymorphisms ( GSTM1 null, GSTT1 null, I105V, and A114V polymorphisms in the GSTP1 genes, and GSTM3 intron 6 polymorphism) available before August, 2005, with investigation of potential sources of heterogeneity. Included in the present meta-analysis were 130 studies, involving a total of 23,452 lung cancer cases and 30,397 controls. In a combined analysis, the relative risks for lung cancer of the GSTM1 null and GSTT1 null polymorphisms were 1.18 (95% confidence interval [CI]: 1.14–1.23) and 1.09 (95% CI: 1.02–1.16), respectively, but in the larger studies they were only 1.04 (95% CI: 0.95–1.14) and 0.99 (95% CI: 0.86–1.11), respectively. In addition to size of study, ethnic background was a significant source of heterogeneity among studies of the GSTM1 null genotype, with possibly weaker associations in studies of individuals of European continental ancestry. Combined analyses of studies of the 105V, 114V, and GSTM3*B variants showed no significant overall associations with lung cancer, yielding per-allele relative risks of 1.04 (95% CI: 0.99–1.09), 1.15 (95% CI: 0.95–1.39), and 1.05 (95% CI: 0.89–1.23), respectively. CONCLUSIONS: The risk of lung cancer is not strongly associated with the I105V and A114V polymorphisms in the GSTP1 gene or with GSTM3 intron 6 polymorphism. Given the non-significant associations in the larger studies, the relevance of the weakly positive overall associations with the GSTM1 null and the GSTT1 null polymorphisms is uncertain. As lung cancer has important environmental causes, understanding any genetic contribution to it in general populations will require the conduct of particularly large and comprehensive studies

    Burden of obesity in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study

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    Mokdad AH, El Bcheraoui C, Afshin A, et al. Burden of obesity in the Eastern Mediterranean Region: findings from the Global Burden of Disease 2015 study. INTERNATIONAL JOURNAL OF PUBLIC HEALTH. 2018;63(Suppl. 1):165-176.We used the Global Burden of Disease (GBD) 2015 study results to explore the burden of high body mass index (BMI) in the Eastern Mediterranean Region (EMR). We estimated the prevalence of overweight and obesity among children (2-19 years) and adults (20 years) in 1980 and 2015. The burden of disease related to high BMI was calculated using the GBD comparative risk assessment approach. The prevalence of obesity increased for adults from 15.1% (95% UI 13.4-16.9) in 1980 to 20.7% (95% UI 18.8-22.8) in 2015. It increased from 4.1% (95% UI 2.9-5.5) to 4.9% (95% UI 3.6-6.4) for the same period among children. In 2015, there were 417,115 deaths and 14,448,548 disability-adjusted life years (DALYs) attributable to high BMI in EMR, which constitute about 10 and 6.3% of total deaths and DALYs, respectively, for all ages. This is the first study to estimate trends in obesity burden for the EMR from 1980 to 2015. We call for EMR countries to invest more resources in prevention and health promotion efforts to reduce this burden
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