A newly deciphered gloss on the Cadmug Gospels (Fulda, Landesbibliothek, MS Bonifatianus 3, folio 39a)

In this article I provide a new edition of the glosses on folio 39a of the 8thcentury Cadmug Gospels. I also correct the reading of one of the glosses on folio 3v

The Old Irish glosses in Bern, Burgerbibliothek, Cod. 207

Eine Edition und Diskussion der altirischen Glossen in Bern, Burgerbibliothek, Cod. 207.In this paper, I provide an edition of the glosses in Bern, Burgerbibliothek, Cod. 207 along with some discussion of their linguistic features

Strategies in tracing linguistic variation in a corpus of Old Irish texts (CorPH)

This article introduces Corpus PalaeoHibernicum (CorPH), a corpus currently consisting of 78 texts in Early Irish (c. 7th–10th cent.) created by the ERC-funded Chronologicon Hibernicum (ChronHib) project by bringing together pre-existing lexical and syntactic databases and adding further crucial texts from the period. In addition to being annotated for POS, morphological and syntactic information, another layer of annotation has been developed for CorPH – ‘Variation Tagging’, i.e. a tagset that numerically encodes synchronic language variation during the Early Irish period, thus allowing for much improved research on the chronological variation among the material. Another new pillar of studying linguistic variation is Bayesian Language Variation Analysis (BLaVA), in order to address the challenge that “not-so-big data” poses to statistical corpus methods. Instead of reflecting feature frequencies, BLaVA models language variation as probabilities of variation

Contact as catalyst: The case for Coptic influence in the development of Arabic negation

This article discusses similar developments in the expression of negation in the histories of Egyptian-Coptic and Arabic and explores the evidence for these respective developments being related by language contact. Both Coptic and Arabic have undergone a development known as Jespersen’s Cycle (JC), whereby an original negative marker is joined by some new element to form a bipartite negative construction. The original marker then becomes optional while the new element becomes the primary negator. We present the results of a corpus study of negation in late Coptic, showing that, at the time when Arabic speakers began to settle in Egypt, the bipartite negative construction still predominated. This being the case, we argue that native speakers of Coptic learning Arabic as a second language played a key role in the genesis of the Arabic bipartite negative construction. More generally, we give reasons to doubt the a priori preference for internal explanations of syntactic change over those involving contact, as well as the assumption that the two are mutually exclusive. Rather, we suggest that not only purely internal but also (partially) contactinduced change can profitably be accounted for in terms of child language acquisition leading to a change in the grammars of individual speakers

Predictive value of cervical cytokine, antimicrobial and microflora levels for pre-term birth in high-risk women

Spontaneous preterm birth (sPTB, delivery <37 weeks gestation), accounts for approximately 10% of births worldwide; the aetiology is multifactorial with intra-amniotic infection being one contributing factor. This study aimed to determine whether asymptomatic women with a history of sPTB or cervical surgery have altered levels of inflammatory/antimicrobial mediators and/or microflora within cervical fluid at 22-24 weeks gestation. External cervical fluid was collected from women with history of previous sPTB and/or cervical surgery at 22-24 weeks gestation (n = 135). Cytokine and antimicrobial peptides were measured on a multiplex platform or by ELISA. qPCR was performed for detection of 7 potentially pathogenic bacterial species. IL-8 and IL-1β levels were lower in women who delivered preterm compared to those who delivered at term (IL-8 P = 0.02; IL-1β P = 0.04). There were no differences in elafin or human beta defensin-1 protein levels between the two groups. Multiple bacterial species were detected in a higher proportion of women who delivered preterm than in those who delivered at term (P = 0.005). Cervical fluid IL-8 and IL-1β and microflora have the potential to be used as biomarkers to predict sPTB in high risk women

Factors influencing accuracy of referral and the likelihood of false positive referral by optometrists in Bradford, United Kingdom

YesAims: Levels of false positive referral to ophthalmology departments can be high. This study aimed to evaluate commonality between false positive referrals in order to find the factors which may influence referral accuracy. Methods: In 2007/08, a sample of 431 new Ophthalmology referrals from the catchment area of Bradford Royal Infirmary were retrospectively analysed. Results: The proportion of false positive referrals generated by optometrists decreases with experience at a rate of 6.2% per year since registration (p < 0.0001). Community services which involved further investigation done by the optometrist before directly referring to the hospital were 2.7 times less likely to refer false positively than other referral formats (p = 0.007). Male optometrists were about half as likely to generate a false positive referral than females (OR = 0.51, p = 0.008) and as multiple/corporate practices in the Bradford area employ less experienced and more female staff, independent practices generate about half the number of false positive referrals (OR = 0.52, p = 0.005). Conclusions: Clinician experience has the greatest effect on referral accuracy although there is also a significant effect of gender with women tending to refer more false positives. This may be due to a different approach to patient care and possibly a greater sensitivity to litigation. The improved accuracy of community services (which often refer directly after further investigation) supports further growth of these schemes.This study was funded by the University of Bradford

The production and consumption activities relating to the celebrity artist

This paper considers the impact of the celebrity artist on the associated production and consumption activities. It also considers the role which entrepreneurial marketing plays in helping to create the celebrity artist aura. The artist Thomas Kinkade is used to illustrate how this occurs in practice. Here, authenticity and nostalgia dimensions are also influential factors. Underpinning these relationships are the roles played out by the media, including communication of celebrity artist identity, and the catalysing of its commodification within the celebrity artist brandscape. An enduring celebrity brand results due to the market creation activities of the celebrity artist. A conceptual model is developed which synthesises the factors behind the production and consumption of the celebrity artist which can stimulate further research. This paper provides innovative insight into the world of the celebrity artist by interrogating the market making and shaping devices behind successful production and consumption practices

Global Expression Profiling in Epileptogenesis: Does It Add to the Confusion?

Since the inception of global gene expression profiling platforms in the mid-1990s, there has been a significant increase in publications of differentially expressed genes in the process of epileptogenesis. In particular for mesial temporal lobe epilepsy, the presence of a latency period between the first manifestation of seizures to chronic epilepsy provides the opportunity for therapeutic interventions at the molecular biology level. Using global expression profiling techniques, approximately 2000 genes have been published demonstrating differential expression in mesial temporal epilepsy. The majority of these changes, however, are specific to laboratory or experimental conditions with only 53 genes demonstrating changes in more than two publications. To this end, we review the current status of gene expression profiling in epileptogenesis and suggest standard guidelines to be followed for greater accuracy and reproducibility of results

The semiology of changing brand image

This article considers the attempted change to the image of an established brand by studying the semiotics within the brand’s historical advertising campaigns. The use of semiotics to study the interpretation of messages is discussed, and the link between interpretation of messages and advertising effectiveness in changing brand image is explored. The authors deconstruct advertisements of a brand to provide a model containing opposing dialectics that may aid managers by highlighting alternative symbolic messages contained in advertisements. Oncwe identified, these alternative symbolic messages may be used to help change brand image and influence advertising effectiveness. Although the study focuses upon a major brand of beer, this is an industry in which there are numerous small firms, and many of those have constrained marketing budgets, and thus need to make sure that their advertising is effective. Equally, entrepreneurial marketing is not to found only in the small firm, and the case study discusses a radical and imaginative brand repositioning of a well established product