802 research outputs found
Technology use in everyday life: Implications for designing for older users
This study examines the experience and attitudes of older adults towards technology and how they compare with younger age groups. Two hundred and thirty seven participants completed an extensive questionnaire exploring their daily lifestyle, use of technology, attitudes towards technology, and perceived difficulty of household devices. The main findings from the study were; (1) there was a strong motivation to learn or to continue learning to use computers by the older group; (2) social connectedness influenced how the older group used or would like to use technology and also why some preferred not to use it; and finally (3) there was an age-related increase in perceived difficulty for many household devices, however some devices maintained intergenerational usability. These finding can be used to inform the design of future intergenerational household technologies
Defining the origins of multiple emission/excitation in rhenium-bisthiazole complexes
The underlying mechanism of the unusual emissive behavior of [Re(CO) 3 -1,1-bis-4-thiazole-(1,4)-diaminobutane)] bromide (4-BT) has been investigated. Synthesis and spectroscopic characterization of structurally similar isomers ([Re(CO) 3 -1,1-bis-2-thiazole-(1,4)-diaminobutane)] bromide (2-BT)) and the location of triplet states, solid state and low temperature spectroscopic measurements, and DFT calculations show that the photophysical properties are not due to photoisomerization as previously hypothesized. The results show that the unusual emissive behavior is not observed in structural isomers, is specific to the previously reported complex, 4-BT, and may arise from vibrational energy relaxation and vibrational cooling. Translation of the unusual emissive behavior to the solid state offers an interesting platform allowing this complex to be potentially utilized as a probe, sensor or photonic device
Dynamics of ions in the selectivity filter of the KcsA channel
The statistical and dynamical properties of ions in the selectivity filter of the KcsA ion channel are considered on the basis of molecular dynamics (MD) simulations of the KcsA protein embedded in a lipid membrane surrounded by an ionic solution. A new approach to the derivation of a Brownian dynamics (BD) model of ion permeation through the filter is discussed, based on unbiased MD simulations. It is shown that depending on additional assumptions, ion’s dynamics can be described either by under-damped Langevin equation with constant damping and white noise or by Langevin equation with a fractional memory kernel. A comparison of the potential of the mean force derived from unbiased MD simulations with the potential produced by the umbrella sampling method demonstrates significant differences in these potentials. The origin of these differences is an open question that requires further clarifications
Large-scale collective motion of RFGC galaxies
We processed the data about radial velocities and HI linewidths for 1678 flat
edge-on spirals from the Revised Flat Galaxy Catalogue. We obtained the
parameters of the multipole components of large-scale velocity field of
collective non-Hubble galaxy motion as well as the parameters of the
generalized Tully-Fisher relationship in the "HI line width - linear diameter"
version. All the calculations were performed independently in the framework of
three models, where the multipole decomposition of the galaxy velocity field
was limited to a dipole, quadrupole and octopole terms respectively. We showed
that both the quadrupole and the octopole components are statistically
significant.
On the basis of the compiled list of peculiar velocities of 1623 galaxies we
obtained the estimations of cosmological parameters Omega_m and sigma_8. This
estimation is obtained in both graphical form and as a constraint of the value
S_8=sigma_8(Omega_m/0.3)^0.35 = 0.91 +/- 0.05.Comment: Accepted for publication in Astrophysics and Space Scienc
Dynamics of Coronal Bright Points as seen by Sun Watcher using Active Pixel System detector and Image Processing (SWAP), Atmospheric Imaging Assembly AIA), and Helioseismic and Magnetic Imager (HMI)
The \textit{Sun Watcher using Active Pixel system detector and Image
Processing}(SWAP) on board the \textit{PRoject for OnBoard Autonomy\todash 2}
(PROBA\todash 2) spacecraft provides images of the solar corona in EUV channel
centered at 174 \AA. These data, together with \textit{Atmospheric Imaging
Assembly} (AIA) and the \textit{Helioseismic and Magnetic Imager} (HMI) on
board \textit{Solar Dynamics Observatory} (SDO), are used to study the dynamics
of coronal bright points. The evolution of the magnetic polarities and
associated changes in morphology are studied using magnetograms and
multi-wavelength imaging. The morphology of the bright points seen in
low-resolution SWAP images and high-resolution AIA images show different
structures, whereas the intensity variations with time show similar trends in
both SWAP 174 and AIA 171 channels. We observe that bright points are seen in
EUV channels corresponding to a magnetic-flux of the order of Mx. We
find that there exists a good correlation between total emission from the
bright point in several UV\todash EUV channels and total unsigned photospheric
magnetic flux above certain thresholds. The bright points also show periodic
brightenings and we have attempted to find the oscillation periods in bright
points and their connection to magnetic flux changes. The observed periods are
generally long (10\todash 25 minutes) and there is an indication that the
intensity oscillations may be generated by repeated magnetic reconnection
Pharmacology and Surface Electrostatics of the K Channel Outer Pore Vestibule
In spite of a generally well-conserved outer vestibule and pore structure, there is considerable diversity in the pharmacology of K channels. We have investigated the role of specific outer vestibule charged residues in the pharmacology of K channels using tetraethylammonium (TEA) and a trivalent TEA analog, gallamine. Similar to Shaker K channels, gallamine block of Kv3.1 channels was more sensitive to solution ionic strength than was TEA block, a result consistent with a contribution from an electrostatic potential near the blocking site. In contrast, TEA block of another type of K channel (Kv2.1) was insensitive to solution ionic strength and these channels were resistant to block by gallamine. Neutralizing either of two lysine residues in the outer vestibule of these Kv2.1 channels conferred ionic strength sensitivity to TEA block. Kv2.1 channels with both lysines neutralized were sensitive to block by gallamine, and the ionic strength dependence of this block was greater than that for TEA. These results demonstrate that Kv3.1 (like Shaker) channels contain negatively charged residues in the outer vestibule of the pore that influence quaternary ammonium pharmacology. The presence of specific lysine residues in wild-type Kv2.1 channels produces an outer vestibule with little or no net charge, with important consequences for quaternary ammonium block. Neutralizing these key lysines results in a negatively charged vestibule with pharmacological properties approaching those of other types of K channels
Observation of a new chi_b state in radiative transitions to Upsilon(1S) and Upsilon(2S) at ATLAS
The chi_b(nP) quarkonium states are produced in proton-proton collisions at
the Large Hadron Collider (LHC) at sqrt(s) = 7 TeV and recorded by the ATLAS
detector. Using a data sample corresponding to an integrated luminosity of 4.4
fb^-1, these states are reconstructed through their radiative decays to
Upsilon(1S,2S) with Upsilon->mu+mu-. In addition to the mass peaks
corresponding to the decay modes chi_b(1P,2P)->Upsilon(1S)gamma, a new
structure centered at a mass of 10.530+/-0.005 (stat.)+/-0.009 (syst.) GeV is
also observed, in both the Upsilon(1S)gamma and Upsilon(2S)gamma decay modes.
This is interpreted as the chi_b(3P) system.Comment: 5 pages plus author list (18 pages total), 2 figures, 1 table,
corrected author list, matches final version in Physical Review Letter
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