Perfilometria dimensional do gesso dentário tipo IV combinado com diferentes diluições do agente plastificante glicerina

Objetivo: Este trabalho avaliou-se a alteração dimensional linear dos gessos odontológicos, sendo submetidos a combinação com glicerina bi-destilada (GC) em 10%, 20% 30%, 40% e 50% de diluição durante o período imediato (t0), 24 horas(t24). Material e Método:O grupo GA:Controle foram água de abastecimento e GB:água destilada. Os grupos dos gessos foram divididos em cinco grupos com diferentes percentuais de diluição de glicerina bi-destilada com dez (n=10) amostras e interagida com o tempo imediato (t0); 24 horas (24). Foi utilizada a máquina de análise de dimensão (perfilômetro) da marca Mitutoyo que avaliou-se a alteração de dimensão de cada grupo de material interagido com os agentes químicos conforme o tempo de armazenamento e percentual de diluição. Em seguida, os dados foram analisados estatisticamente, obtendo os resultados e conseqüentemente foi realizados as tabelas e gráficos e as correlações lineares. Resultados:Este estudo mostrou que glicerina a 10% apresentou valores de alterações dimensionais similares ao grupo com água destilada. Os demais percentuais de glicerina tiveram valores de alterações dimensionais maiores. O grupo cloreto de sódio apresentou o maior valor de alteração dimensional promovendo expansão das amostras. ANOVA e T-student

Silver nanoparticles in resin luting cements: antibacterial and physiochemical properties

Background: Silver has a long history of use in medicine as an antimicrobial and anti-inflammatory agent. Silver nanoparticles (NAg) offer the possibility to control the formation oral biofilms through the use of nanoparticles with biocidal, anti-adhesive, and delivery abilities. This study aims to evaluate the antibacterial effect of resin luting cements with and without NAg, and their influence on color, sorption and solubility. Material and methods: NAg were incorporated to two dual-cured resin cements (RelyX ARC (RA) color A1 and RelyX U200 (RU) color A2) in two concentrations (0.05% and 0.07%, in weight), obtaining six experimental groups. Disc specimens (1x6mm) were obtained to verify the antibacterial effect against Streptococcus mutans in BHI broth after immersion for 1min, 5min, 1h, 6h, and 24h (n=3), through optical density readings. Specimens were evaluated for color changes after addition of NAg with a spectrophotometer (n=10). Sorption and solubility tests were also performed, considering storage in water or 75% ethanol for 28 days (n=5), according to ISO 4049:2010. Data were subjected to statistical analysis with ANOVA and Tukey (p=0.05). Results: The optical density of the culture broths indicated bacterial growth, with and without NAg. NAg produced significant color change on the resin cements, especially in RA. Solubility values were very low for all groups, while sorption values raised with NAg. The cements with NAg did not show antibacterial activity against S. mutans. They also showed perceptible color change and higher sorption than the materials without NAg. Conclusions: The resin luting cements with NAg addition did not show antibacterial activity against S. mutans. They also showed perceptible color change and higher sorption than the materials without NAg

A preliminary study of the antibacterial potential of cetylpyridinium chloride in root canals infected by E. faecalis

The aim of this preliminary study was to verify the antibacterial potential of cetylpyridinium chloride (CPC) in root canals infected by Enterococcus faecalis. Forty human maxillary anterior teeth were prepared and inoculated with E. faecalis for 60 days. The teeth were randomly assigned to the following groups: 1: Root canal preparation (RCP) + 0.1% CPC with positive-pressure irrigation (PPI, Conventional, NaviTip®); 2: RCP + 0.2% CPC PPI; 3: RCP + 2.5% NaOCl PPI; 4: RCP + 2.5% NaOCl with negative-pressure irrigation system (NPI, EndoVac®); 5: Positive control; and 6: Negative control. Four teeth of each experimental group were evaluated by culture and 4 by scanning electron microscopy (SEM). In all teeth, the root canals were dried and filled with 17% EDTA (pH 7.2) for 3 min for smear layer removal. Samples from the infected root canals were collected and immersed in 7 mL of Letheen Broth (LB), followed by incubation at 37°C for 48 h. Bacterial growth was analyzed by turbidity of culture medium and then observed with a UV spectrophotometer. The irrigating solutions were further evaluated for antimicrobial effect by an agar diffusion test.The statistical data were treated by means, standard deviation, Kruskal-Wallis test and analysis of variance. Significance level was set at 5%. The results showed the presence of E. faecalis after root canal sanitization. The number of bacteria decreased after the use of CPC. In the agar diffusion test, CPC induced large microbial inhibition zones, similar to 2% chlorhexidine and large than 2.5% NaOCl. In conclusion, cetylpyridinium chloride showed antibacterial potential in endodontic infection with E. faecalis

Caracterização Físico-química e Clones de Batata-doce de Polpa Alaranjada nas Condições de Palmas-TO

Resumo: o objetivo deste artigo foi obter informações a respeito da produtividade e características físicas químicas da batata-doce de polpa alaranjada visando o consumo humano e animal e sua potencialidade para utilização na indústria alimentícia. Após análise estatística dos resultados obtidos (produtividade, danos mínimos causados por insetos, matéria-seca (massa seca), cinzas, sólidos solúveis e amido), os clones BD# 09 e do BD#35 foram os mais produtivos e com os melhores valores de danos mínimos, o clone BD#02 é o mais produtivo em termo de matéria-seca, o BD#36 destacou-se com o maior percentual de amido com 47,62%. Palavras-chave: Batata-doce. Características ficisoquímicas. Amido

Microscopia digital das pontas diamantadas para acabamento dos pinos intra radiculares pré-fabricados estéticos

Objetivo: O objetivo deste trabalho foi a avaliação por meio de imagens de microscopia digital utilizando diferentes tipos de acabamento. Métodos: Neste trabalho foram utilizados pinos de fibra de vidro de tamanho n.1, foram realizados acabamento com a seguintes pontas diamantadas: 3195, 3195F e 3195FF, formando um total de 4 grupos sendo grupo controle e os outros 3 pertencente a cada ponta diamantada respectivamente. Posteriormente foi analisado em Microscópio se houve alguma alteração em sua estrutura superficial. Resultados: No primeiro grupo foram realizados acabamentos com a ponta diamantada 3195F, apresentando então menor preservação da estrutura superficial do pino. No segundo grupo foram realizados acabamentos com a ponta diamantada 3195FF, apresentando assim variação quanto a preservação da estrutura superficial do pino. No terceiro grupo foram realizados acabamentos com a ponta diamantada 3195, obtendo assim melhor preservação da estrutura superficial do pino. Já o quarto grupo foi utilizado como grupo controle. Conclusão: A utilização da ponta diamantada 3195 apresentou maior padrão de homogeneidade e preservação da estrutura do material

The Barretos Cancer Hospital Animal Facility: implementation and results of a dedicated platform for preclinical oncology models

The Barretos Cancer Hospital Animal Facility (BCHAF) is a unique facility in Brazil exclusively dedicated to working with animal models for cancer research. In this article, we briefly present our modern facility and the main experiments performed, focusing on mutant strains of mice (PTCH-knockout and ApcMin mice), xenograft models, and patient-derived xenografts (PDXs). Our results show the progress and challenges in establishing these models and the need for having an appropriate representation of our cancer population to better understand tumor biology and to identify cancer biomarkers, which could be putatively targeted, allowing for personalized therapy.This study was funded by the Public Ministry of Labor Campinas (Research, Prevention and Education of Occupational Cancer) and by Pio XII Foundation, Barretos Cancer Hospital internal funds, Grant Number: 13/2021

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe