Estudio diagnóstico del clima organizacional en una dependencia educativa

The research raised as a general objective, to determine the concordance between the organizational climate and the factors of recognition, environment and work performance of the workers of the Mochis Faculty of Social Work of the Autonomous University of Sinaloa, 2022; the focused and validated methodology was defined and applied in search of feasible results, the variables that were analyzed were recognition, relationships and work performance; It is a descriptive study of non-experimental design, with a quantitative approach, of a transversal type, which are designed to measure situations and factors that affect the development and quality of a form of organization, the population is finite, made up of 57 workers; was applied to a total of 31 active employees, which offers 54.38% of the total, the survey instrument is focused on identifying the work and organizational climate, which is validated by Litwin and Stringer, Chavarría (1984), the instrument it was rigorously applied and analyzed and the Cronbach's Alpha reliability test offered a recognition coefficient of 0.976 for the environment variable and 0.987, for the performance variable 0.931 and indicating that the applied instrument is highly reliable; the final result has a lower significance of .004 through Pearson's Chi-square feasibility analysis; It is concluded, offering as a result a feasible correlation between the variables in the analysis of the organizational climate of the indicated academic unit, and affirming that there is an influence on job performance regarding recognition, environment and job performance, identifying a significant correlation in variables.La investigación planteó como objetivo general, determinar la concordancia entre el clima organizacional y los factores de reconocimiento, ambiente y rendimiento laboral de los trabajadores de la Facultad de Trabajo Social Mochis de la Universidad Autónoma de Sinaloa, 2022; se definió y aplico la metodología enfocada y validada en busca de resultados factibles, las variables que se analizaron fueron, reconocimiento, relaciones y rendimiento laboral; es un estudio descriptivo de diseño no experimental, con enfoque cuantitativo, de tipo transversal, los cuales son diseñados para medir situaciones y factores que inciden en el desarrollo y la calidad de una forma de organización, la población es finita, conformada por 57 trabajadores, se aplicó a un total de 31 empleados en activo,  lo cual ofrece un 54.38% del total, el instrumento de encuesta está enfocado a identificar el clima laboral y organizacional,  mismo que es validado de Litwin y Stringer, Chavarría (1984), el instrumento fue aplicado y analizado de forma rigurosa y la prueba de fiabilidad del Alfa de Cronbach ofreció un coeficiente de reconocimiento 0.976, para la variable ambiente 0.987 y para la variable rendimiento 0.931 señalando que el instrumento aplicado es altamente confiable; el resultado final tiene una significancia inferior de .004 a través del análisis de viabilidad Chi-cuadrado de Pearson; se concluye, ofreciendo como resultado una correlación factible entre las variables en el análisis del clima organizacional de la unidad académica señalada, y afirmando que sí hay influencia en el desempeño laboral respecto al reconocimiento, el ambiente y el rendimiento laboral, identificando una correlación significativa en las variables

La relocalización alimentaria débil: desconexión entre agentes del territorio y planificación espacial

El interés hacia las redes alimentarias locales y la reconexión entre producción y consumo ha ido creciendo desde mediados de los años 80. El objetivo de relocalización va permeando las agendas urbanas y aumentan las investigaciones, propuestas y recomendaciones que plantean la importancia de la ordenación territorial y los planes espaciales para relocalizar el sistema alimentario. Sin embargo, ni el sector agrario ni los agentes que en la práctica gestionan el territorio, perciben como un factor relevante la componente espacial y de ordenación. Con el proyecto ArimNET DIVERCROP hemos analizado la zona de la Vega Baja del Jarama, próxima al área metropolitana de Madrid. Mediante metodologías participativas se ha trabajado con agentes del sector agrario, de la investigación y de las instituciones locales, así como con entidades de la economía social y movimientos sociales. Los resultados de la investigación constatan que hay en estos agentes un deseo y voluntad de recuperar la producción hortícola y ganadera y ligarla a los mercados locales, pero queda fuera de su imaginario el papel de los planes de urbanismo y de ordenación espacial, a distintas escalas. No identifican los planes espaciales como elementos sobre los que incidir para lograr sus objetivos, más allá de las estrategias tradicionalmente defensivas frente a planes de expansión de suelos artificiales, infraestructuras y actividades extractivas

Marcadores clínicos de mal pronóstico intrahospitalario en pacientes con síndrome coronario agudo con elevación del segmento ST

ResumenIntroducción: La valoración del pronóstico desde el momento del ingreso hospitalario constituye una herramienta útil para el médico al  prevenir complicaciones a corto y largo plazo.  Objetivo: Determinar la asociación de la edad, el sexo femenino, la taquicardia, la tensión arterial sistólica, la tensión arterial diastólica y la escala de Killip Kimball>1 en el momento del ingreso con el pronóstico intrahospitalario. Diseño metodológico: Estudio prospectivo de cohorte con 90 pacientes que ingresaron con diagnóstico de síndrome coronario agudo con elevación ST, en el Hospital Universitario “General Calixto García”  desde mayo 2013 hasta abril 2014. Se realizó revisión de antecedentes patológicos personales, datos clínicos, electrocardiograma y evolución intrahospitalaria. Para la asociación de variables con el pronóstico se utilizó la prueba del riesgo relativo con su intervalo de confianza, t de Student y la prueba de x2. Se consideró significación estadística p=70 años [RR=1,813(IC=1,024 – 3,208), p=0,043], la taquicardia[RR=3,429 (IC=2,250 – 5,226), p=0,000], la tensión arterial sistólica I [RR=1,868 (IC=1,061 – 3,289), p=0,045] aumentaron el riesgo de complicaciones intrahospitalarias, el sexo femenino [RR=1,402 (IC=0,784 – 2,508), p=0,264] no se asoció con el mal pronóstico. Conclusiones: La edad >=70 años, la taquicardia, la tensión arterial sistólica I pueden utilizarse como marcadores de mal pronóstico intrahospitalario desde el momento de la admisión en pacientes con síndrome coronario agudo con elevación del segmento ST.Palabras claves: Síndrome coronario agudo, elevación del segmento ST, mal pronóstico.Title: Clinical markers of intrahospital bad prognosis in patients with ST elevation in acute coronary syndrome. AbstractThe values of prognosis when the patients’ admission at hospital is very important for physician in prevent a short or long time complications. Objective:  determine the association between age, female sex,  tachycardia, systolic blood pressure, diastolic blood pressure and Killip Kimball score >I in admission the patients with prognosis inside hospital. Method: prospective, cohort study in ninety patients whit diagnosis ST elevated acute coronary syndrome, in “Calixto García” University Hospital since 2013 may to 201 april. We explored pathologic personal history, clinical date, electrocardiogram, inside hospitality evolution. Relative risk test, t-student test and X2 test were performed to investigate association between variables and prognosis. P value =70 years [RR=1,813(IC=1,024 – 3,208), p=0,043], tachycardia  [RR=3,429 (IC=2,250 – 5,226), p=0,000], systolic blood pressure I  [RR=1,868 (IC=1,061 – 3,289), p=0,045] increased risk complications inside hospitality, female sex don’t had association with bad prognosis.  Conclusions: age >=70 years, systolic blood pressure I  it can be utilize as bad risk markers inside hospitality since admission in patients with ST elevated acute coronary syndrome. Key word: acute coronary syndrome, ST elevated, bad prognosis

ELOVL6 Genetic Variation Is Related to Insulin Sensitivity: A New Candidate Gene in Energy Metabolism

BACKGROUND: The elongase of long chain fatty acids family 6 (ELOVL6) is an enzyme that specifically catalyzes the elongation of saturated and monounsaturated fatty acids with 12, 14 and 16 carbons. ELOVL6 is expressed in lipogenic tissues and it is regulated by sterol regulatory element binding protein 1 (SREBP-1). OBJECTIVE: We investigated whether ELOVL6 genetic variation is associated with insulin sensitivity in a population from southern Spain. DESIGN: We undertook a prospective, population-based study collecting phenotypic, metabolic, nutritional and genetic information. Measurements were made of weight and height and the body mass index (BMI) was calculated. Insulin resistance was measured by homeostasis model assessment. The type of dietary fat was assessed from samples of cooking oil taken from the participants' kitchens and analyzed by gas chromatography. Five SNPs of the ELOVL6 gene were analyzed by SNPlex. RESULTS: Carriers of the minor alleles of the SNPs rs9997926 and rs6824447 had a lower risk of having high HOMA_IR, whereas carriers of the minor allele rs17041272 had a higher risk of being insulin resistant. An interaction was detected between the rs6824447 polymorphism and the intake of oil in relation with insulin resistance, such that carriers of this minor allele who consumed sunflower oil had lower HOMA_IR than those who did not have this allele (P = 0.001). CONCLUSIONS: Genetic variations in the ELOVL6 gene were associated with insulin sensitivity in this population-based study

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb^-1. The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final version published in European Physical Journal

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration

Antimalarial drug artemether inhibits neuroinflammation in BV2 microglia through Nrf2-dependent mechanisms

Artemether, a lipid-soluble derivative of artemisinin has been reported to possess anti-inflammatory properties. In this study, we have investigated the molecular mechanisms involved in the inhibition of neuroinflammation by the drug. The effects of artemether on neuroinflammation-mediated HT22 neuronal toxicity were also investigated in a BV2 microglia/HT22 neuron co-culture. To investigate effects on neuroinflammation, we used LPS-stimulated BV2 microglia treated with artemether (5-40µM) for 24 hours. ELISAs and western blotting were used to detect pro inflammatory cytokines, nitric oxide, PGE2, iNOS, COX-2 and mPGES-1. BACE-1 activity and Aβ levels were measured with ELISA kits. Protein levels of targets in NF-kappaB and p38 MAPK signalling, as well as HO-1, NQO1 and Nrf2 were also measured with western blot. NF-kappaB binding to the DNA was investigated using EMSA. MTT, DNA fragmentation and ROS assays in BV2-HT22 neuronal co-culture were used to evaluate the effects of artemether on neuroinflammation-induced neuronal death. The role of Nrf2 in the anti-inflammatory activity of artemether was investigated in BV2 cells transfected with Nrf2 siRNA. Artemether significantly suppressed pro-inflammatory mediators (NO/iNOS, PGE2/COX-2/mPGES-1, TNFα, and IL-6), Aβ and BACE-1 in BV2 cells following LPS stimulation. These effects of artemether were shown to be mediated through inhibition of NF-kappaB and p38MAPK signalling. Artemether produced increased levels of HO-1, NQO1 and GSH in BV2 microglia. The drug activated Nrf2 activity by increasing nuclear translocation of Nrf2 and its binding to antioxidant response elements in BV2 cells. Transfection of BV2 microglia with Nrf2 siRNA resulted in the loss of both anti-inflammatory and neuroprotective activities of artemether. We conclude that artemether induces Nrf2 expression and suggest that Nrf2 mediates the anti-inflammatory effect of artemether in BV2 microglia. Our results suggest that this drug has a therapeutic potential in neurodegenerative disorders

Biodegradation of Pig Manure by the Housefly, Musca domestica: A Viable Ecological Strategy for Pig Manure Management

The technology for biodegradation of pig manure by using houseflies in a pilot plant capable of processing 500–700 kg of pig manure per week is described. A single adult cage loaded with 25,000 pupae produced 177.7±32.0 ml of eggs in a 15-day egg-collection period. With an inoculation ratio of 0.4–1.0 ml eggs/kg of manure, the amount of eggs produced by a single cage can suffice for the biodegradation of 178–444 kg of manure. Larval development varied among four different types of pig manure (centrifuged slurry, fresh manure, manure with sawdust, manure without sawdust). Larval survival ranged from 46.9±2.1%, in manure without sawdust, to 76.8±11.9% in centrifuged slurry. Larval development took 6–11 days, depending on the manure type. Processing of 1 kg of wet manure produced 43.9–74.3 g of housefly pupae and the weight of the residue after biodegradation decreased to 0.18–0.65 kg, with marked differences among manure types. Recommendations for the operation of industrial-scale biodegradation facilities are presented and discussed

Imported malaria in a cosmopolitan European city: A mirror image of the world epidemiological situation

© 2008 Millet et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens