388 research outputs found

    The Principle of Solidarity

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    The ethical basis of trade unionism is the principle of solidarity, according to which “an injury to one is an injury to all.” The principle is analyzed in accordance with three competing interpretations: a “common-interest” interpretation, a “common-fate” interpretation, and a “common front” interpretation. The last of these interpretations, according to which the principle sets out “the terms of a mutually advantageous practice of reliable and reciprocal defence of one another, as if we were each defending ourselves,” is explained and defended

    Optimality and distortionary lobbying: regulating tobacco consumption

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    We examine policies directed at regulating tobacco consumption through three types of instruments: (i) an excise tax hindering consumption by increasing the price of cigarettes, (ii) prevention programs helping consumers to make choices that are more time consistent when trading-off the current pleasure from smoking and its future health harms, and (iii) smoking bans directly restricting consumption. First, on normative grounds, we focus on the optimal design of public policies maximizing the economy’s surplus. Second, in a positive perspective, we investigate how the lobbying activities of the tobacco industry, of smokers, and of anti-tobacco organizations may distort government intervention

    Challenges of beta-deformation

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    A brief review of problems, arising in the study of the beta-deformation, also known as "refinement", which appears as a central difficult element in a number of related modern subjects: beta \neq 1 is responsible for deviation from free fermions in 2d conformal theories, from symmetric omega-backgrounds with epsilon_2 = - epsilon_1 in instanton sums in 4d SYM theories, from eigenvalue matrix models to beta-ensembles, from HOMFLY to super-polynomials in Chern-Simons theory, from quantum groups to elliptic and hyperbolic algebras etc. The main attention is paid to the context of AGT relation and its possible generalizations.Comment: 20 page

    Using multivariate adaptive regression splines to estimate subadult age from diaphyseal dimensions

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    Subadult age estimation is considered the most accurate parameter estimated in a subadult biological profile, even though the methods are deficient and the samples from which they are based are inappropriate. The current study addresses the problems that plague subadult age estimation and creates age estimation models from diaphyseal dimensions of modern children. The sample included 1,310 males and females between the ages of birth and 12 years. Eighteen diaphyseal length and breadth measurements were obtained from Lodox Statscan radiographic images generated at two institutions in Cape Town, South Africa between 2007 and 2012. Univariate and multivariate age estimation models were created using multivariate adaptive regression splines (MARS). K-fold cross-validated 95% prediction intervals (PIs) were created for each model and the precision of each model was assessed.The diaphyseal length models generated the narrowest PIs (two months to six years) for all univariate models. The majority of multivariate models had PIs that ranged from three months to five and six years. Mean bias approximated zero for each model, but most models lost precision after 10 years of age. While univariate diaphyseal length models are recommended for younger children, multivariate models are recommended for older children where the inclusion of more variables minimized the size of the prediction intervals. If diaphyseal lengths are not available, multivariate breadth models are recommended. The present study provides applicable age estimation formulae and explores the advantages and disadvantages of different subadult age estimation models using diaphyseal dimensions.http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1096-8644hb201

    Demythifying contract farming : evidence from rural South Africa

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    This paper intends to contribute to the on-going debate about whether and how restructured agri-food markets can provide viable market opportunities for small-scale farmers in South Africa. It aims at analyzing contract farming from the small-scale farmer perspective and at better understanding the implications for small-scale farmers regarding contractual arrangements with processing and/or marketing firms. The paper, based on empirical research conducted in the Limpopo Province of South Africa and on a combination of qualitative and econometric analyses, argues however that contract farming is not a panacea for small-scale farmers. On one hand, contract farming improves agricultural production for contract farmers benefiting from increased incomes, enables better access to services and resources and creates new opportunities to participate in markets. However, on the other hand, the results, show that contract farming remains limited and mostly involves the already better-off, who have benefited from specific development paths and public support. This case study shows that contract farming by itself does not appear to provide an efficient means of reducing poverty, nor does it provide an institutional tool through which to improve rural livelihoods. It does therefore, not represent a tool for the majority of small farmers and for redressing the historical imbalances in the South African agricultural sector.http://www.tandfonline.com/loi/ragr20hb201

    Overlapping political budget cycles in the legislative and the executive

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    We advance the literature on political budget cycles by testing separately for cycles in expenditures for elections in the legislative and the executive. Using municipal data, we can separately identify these cycles and account for general year effects. For the executive branch, we show that it is important whether the incumbent re-runs. To account for the potential endogeneity associated with this decision, we apply a unique instrumental variables approach based on age and pension eligibility rules. We find sizable and significant effects in expenditures before council elections and before joint elections when the incumbent re-runs

    Vote buying or (political) business (cycles) as usual?

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    We study the short-run effect of elections on monetary aggregates in a sample of 85 low and middle income democracies (1975-2009). We find an increase in the growth rate of M1 during election months of about one tenth of a standard deviation. A similar effect can neither be detected in established OECD democracies nor in other months. The effect is larger in democracies with many poor and uneducated voters, and in Sub-Saharan Africa, Latin America, and in East-Asia and the Pacific. We argue that the election month monetary expansion is related to systemic vote buying which requires significant amounts of cash to be disbursed right before elections. The finely timed increase in M1 is consistent with this; is inconsistent with a monetary cycle aimed at creating an election time boom; and it cannot be, fully, accounted for by alternative explanations

    Marketing innovation in distribution channels in Macedonian enterprises

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    Distribution channels, as part of the marketing strategy of each enterprise, represent the demand for optimal solutions in bringing products closer to consumers, ie services to consumers. The complexity of this issue stems from the many opportunities that businesses have at their disposal to get closer to consumers. Any possible combination is a particular specificity for the company at some point, but such combinations can change over time and the conditions imposed by the actors present in the markets. The creators of these policies, or strategies, endeavor to constantly carry out new, optimal solutions that will offer the best effects. The rapid development of technology has affected the constantly emerging new ways of distributing products or services. Such opportunities that stand in front of the companies on the Macedonian market are different from those on the world markets. The main reason for the lower level of utilization of the new technical and technological breakthroughs among Macedonian enterprises lies in the limited financial budgets of the country and the enterprises themselves. Also, the underdevelopment of the country, in terms of infrastructure and multimodal staffing, that is, the limited resources to perform on the world markets, can also be seen as a reason for this. Each of these problems is part of the great mosaic of problems that Macedonian enterprises face in their lifetime. Key words: marketing strategy; marketing innovations; marketing best effects; distribution channels; Macedonian enterprise

    AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.

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    AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a decrease in agonist-evoked current mediated by mutant subunits compared to wild-type channels. When GluA2 subunits are co-expressed with GluA1, most GRIA2 mutations cause a decreased current amplitude and some also affect voltage rectification. Our results show that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence that other genetic causes of ID, ASD and DEE also disrupt glutamatergic synaptic transmission
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