Joint Environmental and Economical Analysis of Wastewater Treatment Plants Control Strategies : a Benchmark Scenario Analysis

In this paper, a joint environmental and economic analysis of different Wastewater Treatment Plant (WWTP) control strategies is carried out. The assessment is based on the application of the Life Cycle Assessment (LCA) as a method to evaluate the environmental impact and the Benchmark Simulation Model No. 1 (BSM1). The BSM1 is taken as the benchmark scenario used to implement the control strategies. The Effluent Quality Index (EQI) and the Overall Cost Index (OCI) are two indicators provided by BSM1 and used to evaluate the plant's performance from the efluent quality and the economic points of view, respectively. This work conducts a combined analysis and assessment of ten different control strategies defined to operate a wastewater treatment plant. This analysis includes the usual economic and performance indexes provided by BSM1 joined with the LCA analysis that determines the environmental impact linked to each one of the considered control strategies. It is shown how to get an overall evaluation of the environmental effects by using a normalized graphical representation that can be easily used to compare control strategies from the environmental impact point of view. The use of only the BSM1 indexes provides an assessment that leads to a clustering of control strategies according to the cost/quality tradeoff they show. Therefore, regarding the cost/quality tradeoff, all strategies in the same group are almost equal and do not provide an indication on how to proceed in order to select the appropriate one. It is therefore shown how the fact of adding a new, complementary, evaluation (LCA based) allows either to reinforce a decision that could be taken solely on the basis of the EQI/OCI tradeoff or to select one control strategy among the others

Evaluación clínica de la administración de betametasona intratraqueal para la prevención de complicaciones laringotraqueales posintubacion orotraqueal en pacientes Asa I y II que serán intervenidos en cirugías electivas bajo anestesia general, en el Hospital de la Unión, durante el mes de Noviembre de 2017

El presente documento contiene las partes fundamentales que de acuerdo al método científico, se necesitan para la realización de una investigación con características descriptivas, para la evaluación clínica del uso de betametasona administrada intratraqueal en la prevención de complicaciones laringotraqueales posintubación orotraqueal en pacientes intervenidos en cirugías electivas bajo anestesia general en el Hospital Nacional de La Unión durante el mes de noviembre de 2017

Increased Soil Frost Versus Summer Drought as Drivers of Plant Biomass Responses To Reduced Precipitation: Results from A Globally-Coordinated Field Experiment

Reduced precipitation treatments often are used in field experiments to explore the effects of drought on plant productivity and species composition. However, in seasonally snow-covered regions reduced precipitation also reduces snow cover, which can increase soil frost depth, decrease minimum soil temperatures and increase soil freeze-thaw cycles. Therefore, in addition to the effects of reduced precipitation on plants via drought, freezing damage to overwintering plant tissues at or below the soil surface could further affect plant productivity and relative species abundances during the growing season. We examined the effects of both reduced rainfall (via rain-out shelters) and reduced snow cover (via snow removal) at 13 sites globally (primarily grasslands) within the framework of the International Drought Experiment, a coordinated distributed experiment. Plant cover was estimated at the species level and aboveground biomass was quantified at the functional group level. Among sites, we observed a negative correlation between the snow removal effect on minimum soil temperature and plant biomass production the next growing season. Three sites exhibited significant rain-out shelter effects on plant productivity, but there was no correlation among sites between the rain-out shelter effect on minimum soil moisture and plant biomass. There was no interaction between snow removal and rain-out shelters for plant biomass, although these two factors only exhibited significant effects simultaneously for a single site. Overall, our results reveal that reduced snowfall, when it decreases minimum soil temperatures, can be an important component of the total effect of reduced precipitation on plant productivity

Use of Antihypertensives, Blood Pressure, and Estimated Risk of Dementia in Late Life

ImportanceThe utility of antihypertensives and ideal blood pressure (BP) for dementia prevention in late life remains unclear and highly contested.ObjectivesTo assess the associations of hypertension history, antihypertensive use, and baseline measured BP in late life (age >60 years) with dementia and the moderating factors of age, sex, and racial group.Data Source and Study SelectionLongitudinal, population-based studies of aging participating in the Cohort Studies of Memory in an International Consortium (COSMIC) group were included. Participants were individuals without dementia at baseline aged 60 to 110 years and were based in 15 different countries (US, Brazil, Australia, China, Korea, Singapore, Central African Republic, Republic of Congo, Nigeria, Germany, Spain, Italy, France, Sweden, and Greece).Data Extraction and SynthesisParticipants were grouped in 3 categories based on previous diagnosis of hypertension and baseline antihypertensive use: healthy controls, treated hypertension, and untreated hypertension. Baseline systolic BP (SBP) and diastolic BP (DBP) were treated as continuous variables. Reporting followed the Preferred Reporting Items for Systematic Review and Meta-Analyses of Individual Participant Data reporting guidelines.Main Outcomes and MeasuresThe key outcome was all-cause dementia. Mixed-effects Cox proportional hazards models were used to assess the associations between the exposures and the key outcome variable. The association between dementia and baseline BP was modeled using nonlinear natural splines. The main analysis was a partially adjusted Cox proportional hazards model controlling for age, age squared, sex, education, racial group, and a random effect for study. Sensitivity analyses included a fully adjusted analysis, a restricted analysis of those individuals with more than 5 years of follow-up data, and models examining the moderating factors of age, sex, and racial group.ResultsThe analysis included 17 studies with 34 519 community dwelling older adults (20 160 [58.4%] female) with a mean (SD) age of 72.5 (7.5) years and a mean (SD) follow-up of 4.3 (4.3) years. In the main, partially adjusted analysis including 14 studies, individuals with untreated hypertension had a 42% increased risk of dementia compared with healthy controls (hazard ratio [HR], 1.42; 95% CI 1.15-1.76; P = .001) and 26% increased risk compared with individuals with treated hypertension (HR, 1.26; 95% CI, 1.03-1.53; P = .02). Individuals with treated hypertension had no significant increased dementia risk compared with healthy controls (HR, 1.13; 95% CI, 0.99-1.28; P = .07). The association of antihypertensive use or hypertension status with dementia did not vary with baseline BP. There was no significant association of baseline SBP or DBP with dementia risk in any of the analyses. There were no significant interactions with age, sex, or racial group for any of the analyses.Conclusions and RelevanceThis individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls

Sex differences in dementia risk and risk factors: Individual‐participant data analysis using 21 cohorts across six continents from the COSMIC consortium

Introduction: Sex differences in dementia risk, and risk factor (RF) associations with dementia, remain uncertain across diverse ethno‐regional groups. Methods: A total of 29,850 participants (58% women) from 21 cohorts across six continents were included in an individual participant data meta‐analysis. Sex‐specific hazard ratios (HRs), and women‐to‐men ratio of hazard ratios (RHRs) for associations between RFs and all‐cause dementia were derived from mixed‐effect Cox models. Results: Incident dementia occurred in 2089 (66% women) participants over 4.6 years (median). Women had higher dementia risk (HR, 1.12 [1.02, 1.23]) than men, particularly in low‐ and lower‐middle‐income economies. Associations between longer education and former alcohol use with dementia risk (RHR, 1.01 [1.00, 1.03] per year, and 0.55 [0.38, 0.79], respectively) were stronger for men than women; otherwise, there were no discernible sex differences in other RFs. Discussion: Dementia risk was higher in women than men, with possible variations by country‐level income settings, but most RFs appear to work similarly in women and men

Joint Environmental and Economical Analysis of Wastewater Treatment Plants Control Strategies : a Benchmark Scenario Analysis

In this paper, a joint environmental and economic analysis of different Wastewater Treatment Plant (WWTP) control strategies is carried out. The assessment is based on the application of the Life Cycle Assessment (LCA) as a method to evaluate the environmental impact and the Benchmark Simulation Model No. 1 (BSM1). The BSM1 is taken as the benchmark scenario used to implement the control strategies. The Effluent Quality Index (EQI) and the Overall Cost Index (OCI) are two indicators provided by BSM1 and used to evaluate the plant's performance from the efluent quality and the economic points of view, respectively. This work conducts a combined analysis and assessment of ten different control strategies defined to operate a wastewater treatment plant. This analysis includes the usual economic and performance indexes provided by BSM1 joined with the LCA analysis that determines the environmental impact linked to each one of the considered control strategies. It is shown how to get an overall evaluation of the environmental effects by using a normalized graphical representation that can be easily used to compare control strategies from the environmental impact point of view. The use of only the BSM1 indexes provides an assessment that leads to a clustering of control strategies according to the cost/quality tradeoff they show. Therefore, regarding the cost/quality tradeoff, all strategies in the same group are almost equal and do not provide an indication on how to proceed in order to select the appropriate one. It is therefore shown how the fact of adding a new, complementary, evaluation (LCA based) allows either to reinforce a decision that could be taken solely on the basis of the EQI/OCI tradeoff or to select one control strategy among the others