180 research outputs found
Dynamic processes in magnetic thin films. Domain wall motion and ferromagnetic resonance
NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document.
The objective of the present investigation has been threefold: (1) To characterize domain wall motion in thin ferromagnetic films experimentally and to determine what film properties influence wall mobility. (2) To investigate ferromagnetic resonance relaxation in thin films over a wide range of temperature, frequency, and thickness and to determine what physical relaxation processes contribute to the resonance linewidth. (3) To correlate the losses for wall motion with relaxation processes for ferromagnetic resonance.
Domain wall mobility for Ni-Fe alloy films has been measured as a function of film thickness from 300 to 1650 [angstroms]. Between 300 and 800 [angstroms] the mobility decreases with increasing film thickness, ranging from 8 x 10[superscript 3] cm/sec-0e at 300 [angstroms] to 3 x 10[superscript 3] cm/sec-0e at 800 [angstroms]. Between 900 and 1000 [angstroms], the mobility increases rapidly with increasing film thickness to about 7 x 10[superscript 3] cm/sec-0e. Above 1000 [angstroms], the mobility increases slowly with film thickness. Predictions based on Lorentz microscopy static wall shape measurements are in good agreement with the data for a constant value of the Landau-Lifshitz damping parameter [alpha] = 0.014. Eddy-current losses are negligible. The crosstie and Bloch line structures associated with domain walls in thin films do not appear to influence the mobility. The sharp increase in mobility between 900 and 1000 [angstroms] is associated with a wall structure transition in this region.
Ferromagnetic resonance linewidth measurements have been made for films 150 to 3200 [angstroms] thick at frequencies from 1 to 9 Gc/sec and temperature from 2[degrees]K to 300[degrees]K with the static field in the film plane. Linewidths between 3 0e (1 Gc/sec) and 50 0e (9 Gc/sec) were observed. For fixed thickness, the 300[degrees]K linewidth increases monotonically with anisotropy dispersion. To eliminate dispersion, samples with the smallest linewidth [...] were selected for each thickness. For thickness less than a critical thickness [...]. [...] is independent of thickness, but increases with thickness for D > D[...]. The data are in good agreement with predictions based on two-magnon scattering between the uniform mode and degenerate magnons. Eddy-current losses are not important. The phenomenological damping varies from 0.005 (D = 400[angstroms] to 0.009 (D = 3200[angstroms]) for the 300[degrees]K data. As a function of temperature, the linewidth exhibits a maximum at about 80[degrees]K which is generally larger in thinner films. The amplitude of the peak (as high as 15 0e) is independent of frequency and the peak shifts to slightly higher temperatures with increasing frequency. Two annealing treatments at 150[degrees]C, one in a vacuum and one in hydrogen or oxygen, indicate that the temperature dependence is associated with a surface oxide layer. Two mechanisms, valence exchange and exchange anisotropy, may be important.
Even though phenomenological damping parameters for the two processes, wall motion and resonance, are quite different (at 300[degrees]K), there is a definite connection between the losses. Changes in the wall mobility between 300[degrees]K and 77[degrees]K have been measured for films exhibiting, to varying degrees, the above linewidth effect. From these mobility and linewidth data, the losses for wall motion were found to be directly related to the losses for resonance from 300[degrees]K to 77[degrees]K. There is a definite connection between the relaxation processes which are important for wall motion and those involved in resonance
Fundamental Magnetic Properties and Structural Implications for Nanocrystalline Fe-Ti-N Thin Films
The magnetization (M) as a function of temperature (T) from 2 to 300 K and
in-plane field (H) up to 1 kOe, room temperature easy and hard direction
in-plane field hysteresis loops for fields between -100 and +100 Oe, and 10 GHz
ferromagnetic resonance (FMR) profiles have been measured for a series of
soft-magnetic nano-crystalline 50 nm thick Fe-Ti-N films made by magnetron
sputtering in an in-plane field. The nominal titanium concentration was 3 at. %
and the nitrogen concentrations (xN) ranged from zero to 12.7 at. %. The
saturation magnetization (Ms) vs. T data and the extracted exchange parameters
as a function of xN are consistent with a lattice expansion due to the addition
of interstitial nitrogen in the body-centered-cubic (bcc) lattice and a
structural transition to body-centered-tetragonal (bct) in the 6-8 at. %
nitrogen range. The hysteresis loop and FMR data show a consistent picture of
the changes in both the uniaxial and cubic anisotropy as a function of xN.
Films with xN > 1.9 at. % show an overall uniaxial anisotropy, with an
anisotropy field parameter Hu that increases with xN. The corresponding
dispersion averaged uniaxial anisotropy energy density parameter = HuMs/2
is a linear function of xN, with a rate of increase of 950 erg/cm3 per at. %
nitrogen. The estimated uniaxial anisotropy energy per nitrogen atom is 30
J/mol, a value consistent with other systems. For xN below 6 at. %, the scaling
of coercive force Hc data with the sixth power of the grain size D indicate a
grain averaged effective cubic anisotropy energy density parameter that is
about an order of magnitude smaller that the nominal K1 values for iron, and
give a quantitative vs. D response that matches predictions for exchange
coupled random grains with cubic anisotropy.Comment: 13 pages, 7 figure
Observation of Spin Wave Soliton Fractals in Magnetic Film Active Feedback Rings
The manifestation of fractals in soliton dynamics has been observed for the
first time. The experiment utilized self-generated spin wave envelope solitons
in a magnetic film based active feedback ring. At high ring gain, the soliton
that circulates in the ring breathes in a fractal pattern. The corresponding
power frequency spectrum shows a comb structure, with each peak in the comb
having its own comb, and so on, to finer and finer scales.Comment: 4 pages, 4 figure
Thinking like a man? The cultures of science
Culture includes science and science includes culture, but conflicts between the two traditions persist, often seen as clashes between interpretation and knowledge. One way of highlighting this false polarity has been to explore the gendered symbolism of science. Feminism has contributed to science studies and the critical interrogation of knowledge, aware that practical knowledge and scientific understanding have never been synonymous. Persisting notions of an underlying unity to scientific endeavour have often impeded rather than fostered the useful application of knowledge. This has been particularly evident in the recent rise of molecular biology, with its delusory dream of the total conquest of disease. It is equally prominent in evolutionary psychology, with its renewed attempts to depict the fundamental basis of sex differences. Wars over science have continued to intensify over the last decade, even as our knowledge of the political, economic and ideological significance of science funding and research has become ever more apparent
Implementing health research through academic and clinical partnerships : a realistic evaluation of the Collaborations for Leadership in Applied Health Research and Care (CLAHRC)
Background: The English National Health Service has made a major investment in nine partnerships between
higher education institutions and local health services called Collaborations for Leadership in Applied Health
Research and Care (CLAHRC). They have been funded to increase capacity and capability to produce and
implement research through sustained interactions between academics and health services. CLAHRCs provide a
natural ‘test bed’ for exploring questions about research implementation within a partnership model of delivery.
This protocol describes an externally funded evaluation that focuses on implementation mechanisms and
processes within three CLAHRCs. It seeks to uncover what works, for whom, how, and in what circumstances.
Design and methods: This study is a longitudinal three-phase, multi-method realistic evaluation, which
deliberately aims to explore the boundaries around knowledge use in context. The evaluation funder wishes to see
it conducted for the process of learning, not for judging performance. The study is underpinned by a conceptual
framework that combines the Promoting Action on Research Implementation in Health Services and Knowledge to
Action frameworks to reflect the complexities of implementation. Three participating CLARHCS will provide indepth
comparative case studies of research implementation using multiple data collection methods including
interviews, observation, documents, and publicly available data to test and refine hypotheses over four rounds of
data collection. We will test the wider applicability of emerging findings with a wider community using an
interpretative forum.
Discussion: The idea that collaboration between academics and services might lead to more applicable health
research that is actually used in practice is theoretically and intuitively appealing; however the evidence for it is
limited. Our evaluation is designed to capture the processes and impacts of collaborative approaches for
implementing research, and therefore should contribute to the evidence base about an increasingly popular (e.g.,
Mode two, integrated knowledge transfer, interactive research), but poorly understood approach to knowledge
translation. Additionally we hope to develop approaches for evaluating implementation processes and impacts
particularly with respect to integrated stakeholder involvement
Physicians' messages in problematic sickness certification: a narrative analysis of case reports
<p>Abstract</p> <p>Background</p> <p>Many physicians find sickness certification tasks problematic. There is some knowledge about situations that are experienced as problematic, whereas less is understood about how physicians respond to the problems they face. One way to acquire such knowledge is to consider "reflection-in-action", aspects of which are expressed in the physician's interpretation of the patient's story. The aim of this study was to gain knowledge about the meaning content of case reports about problematic sickness certification. Specifically, we looked for possible messages to the colleagues intended to read the reports.</p> <p>Methods</p> <p>A narrative approach was used to analyse reports about problematic sickness certification cases that had been written by GPs and occupational health service physicians as part of a sickness insurance course. The analysis included elements from both thematic and structural analysis. Nineteen case reports were used in the actual analysis and 25 in the validation of the results. Main narrative qualities and structural features of the written case reports were explored.</p> <p>Results</p> <p>Five types of messages were identified in the case reports, here classified as "a call for help", "a call for understanding", "hidden worries", "in my opinion", and "appearing neutral". In the reports, the physicians tried to achieve neutrality in their writing, and the patients' stories tended to be interpreted within a traditional biomedical framework. In some cases there was an open request for help, in others it was not obvious that the physician had any problems. Overall, the messages were about having problems as such, rather than the specific features of the problems.</p> <p>Conclusions</p> <p>The case reports clearly demonstrated different ways of writing about problems that arise during sickness certification, from being neutral and not mentioning the problems to being emotionally involved and asking for help. The general character of the messages suggests that they are also relevant for case reports in problematic areas other than sickness certification. If pertinent relationships can be found between reflection-in-practice and the narrative writing about practice, they will provide an approach to further research concerning consultations perceived as problematic and also to medical education.</p
Phylogenetic relationships and molecular evolution in uropeltid snakes (Serpentes: Uropeltidae): allozymes and albumin immunology
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73950/1/j.1095-8312.1990.tb00541.x.pd
The influence of social capital on employers’ use of occupational health services: a qualitative study
Gene Expression Profile of Neuronal Progenitor Cells Derived from hESCs: Activation of Chromosome 11p15.5 and Comparison to Human Dopaminergic Neurons
BACKGROUND: We initiated differentiation of human embryonic stem cells (hESCs) into dopamine neurons, obtained a purified population of neuronal precursor cells by cell sorting, and determined patterns of gene transcription.
METHODOLOGY: Dopaminergic differentiation of hESCs was initiated by culturing hESCs with a feeder layer of PA6 cells. Differentiating cells were then sorted to obtain a pure population of PSA-NCAM-expressing neuronal precursors, which were then analyzed for gene expression using Massive Parallel Signature Sequencing (MPSS). Individual genes as well as regions of the genome which were activated were determined.
PRINCIPAL FINDINGS: A number of genes known to be involved in the specification of dopaminergic neurons, including MSX1, CDKN1C, Pitx1 and Pitx2, as well as several novel genes not previously associated with dopaminergic differentiation, were expressed. Notably, we found that a specific region of the genome located on chromosome 11p15.5 was highly activated. This region contains several genes which have previously been associated with the function of dopaminergic neurons, including the gene for tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine biosynthesis, IGF2, and CDKN1C, which cooperates with Nurr1 in directing the differentiation of dopaminergic neurons. Other genes in this region not previously recognized as being involved in the functions of dopaminergic neurons were also activated, including H19, TSSC4, and HBG2. IGF2 and CDKN1C were also found to be highly expressed in mature human TH-positive dopamine neurons isolated from human brain samples by laser capture.
CONCLUSIONS: The present data suggest that the H19-IGF2 imprinting region on chromosome 11p15.5 is involved in the process through which undifferentiated cells are specified to become neuronal precursors and/or dopaminergic neurons
Global and national Burden of diseases and injuries among children and adolescents between 1990 and 2013
Importance The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce.
Objective To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged <5 years), older children (aged 5-9 years), and adolescents (aged 10-19 years) between 1990 and 2013 in 188 countries from the Global Burden of Disease (GBD) 2013 study.
Evidence Review Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates.
Findings Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905 059 deaths; 95% UI, 810 304-998 125), diarrheal diseases among older children (38 325 deaths; 95% UI, 30 365-47 678), and road injuries among adolescents (115 186 deaths; 95% UI, 105 185-124 870). Iron deficiency anemia was the leading cause of years lived with disability among children and adolescents, affecting 619 (95% UI, 618-621) million in 2013. Large between-country variations exist in mortality from leading causes among children and adolescents. Countries with rapid declines in all-cause mortality between 1990 and 2013 also experienced large declines in most leading causes of death, whereas countries with the slowest declines had stagnant or increasing trends in the leading causes of death. In 2013, Nigeria had a 12% global share of deaths from lower respiratory tract infections and a 38% global share of deaths from malaria. India had 33% of the world’s deaths from neonatal encephalopathy. Half of the world’s diarrheal deaths among children and adolescents occurred in just 5 countries: India, Democratic Republic of the Congo, Pakistan, Nigeria, and Ethiopia.
Conclusions and Relevance Understanding the levels and trends of the leading causes of death and disability among children and adolescents is critical to guide investment and inform policies. Monitoring these trends over time is also key to understanding where interventions are having an impact. Proven interventions exist to prevent or treat the leading causes of unnecessary death and disability among children and adolescents. The findings presented here show that these are underused and give guidance to policy makers in countries where more attention is needed
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