Degermed corn distiller’s grains with solubles (DGS) have feed value similar to traditional distiller’s grains

Rapid expansion of the fuel ethanol industry has greatly increased availability of distillery byproducts. Distiller\u27s grains with solubles (DGS) are the predominant byproduct of fermenting grains into fuel ethanol. During this process, starch is removed from the grain and the residual components of the grain are concentrated in the DGS. Improvements in the conversion of cereal grains to ethanol have been fueled by recent changes in the production process. Broin Companies (Sioux Falls, SD) have developed a technology that removes the germ before the fermentation process. The resulting byproduct contains more protein, less crude fat, and less phosphorus compared to traditional distiller\u27s grains. Feeding even modest levels of DGS can contribute to greater phosphorus excretion from feedlots, suggesting that strategies aimed at reducing phosphorus levels are well warranted. The objective of this study was to compare diets based on steam-flaked corn with and without DGS and to compare a highprotein, low-fat, low-phosphorus byproduct to more traditional distiller\u27s grains

Chondroitin-based nanoplexes as peptide delivery systems-Investigations into the self-assembly process, solid-state and extended release characteristics

YesA new type of self-assembled polyelectrolyte complex nanocarrier composed of chondroitin (CHON) and protamine (PROT) was designed and the ability of the carriers to bind salmon calcitonin (sCT) was examined. The response of sCT-loaded CHON/PROT NPs to a change in the properties of the liquid medium, e.g. its pH, composition or ionic strength was studied and in vitro peptide release was assessed. The biocompatibility of the NPs was evaluated in Caco-2 cells. CHON/PROT NPs were successfully obtained with properties that were dependent on the concentration of the polyelectrolytes and their mixing ratio. X-ray diffraction determined the amorphous nature of the negatively charged NPs, while those with the positive surface potential were semi-crystalline. sCT was efficiently associated with the nanocarriers (98-100%) and a notably high drug loading (13-38%) was achieved. The particles had negative zeta potential values and were homogenously dispersed with sizes between 60 and 250 nm. CHON/PROT NPs released less than 10% of the total loaded peptide in the first hour of the in vitro release studies. The enthalpy of the decomposition exotherm correlated with the amount of sCT remaining in NPs after the release experiments. The composition of medium and its ionic strength was found to have a considerable influence on the release of sCT from CHON/PROT NPs. Complexation to CHON markedly reduced the toxic effects exerted by PROT and the NPs were compatible and well tolerated by Caco-2 cells

The Octonionic Membrane

We generalize the supermembrane solution of D=11 supergravity by permitting the 4-form $G$ to be either self-dual or anti-self-dual in the eight dimensions transverse to the membrane. After analyzing the supergravity field equations directly, and also discussing necessary conditions for unbroken supersymmetry, we focus on two specific, related solutions. The self-dual solution is not asymptotically flat. The anti-self-dual solution is asymptotically flat, has finite mass per unit area and saturates the same mass=charge Bogomolnyi bound as the usual supermembrane. Nevertheless, neither solution preserves any supersymmetry. Both solutions involve the octonionic structure constants but, perhaps surprisingly, they are unrelated to the octonionic instanton 2-form $F$, for which $TrF \wedge F$ is neither self-dual nor anti-self-dual.Comment: 17 pages, Latex; enhanced discussion on supersymmetry, some references adde

Ricci-Flat Branes

Up to overall harmonic factors, the D8-brane solution of the massive type IIA supergravity theory is the product of nine-dimensional Minkowski space (the worldvolume) with the real line (the transverse space). We show that the equations of motion allow for the worldvolume metric to be generalised to an arbitrary Ricci-flat one. If this nine-dimensional Ricci-flat manifold admits Killing spinors, then the resulting solutions are supersymmetric and satisfy the usual Bogomol'nyi bound, although they preserve fewer than the usual one half of the supersymmetries. We describe the possible choices of such manifolds, elaborating on the connection between the existence of Killing spinors and the self-duality condition on the curvature two-form. Since the D8-brane is a domain wall in ten dimensions, we are led to consider the general case: domain walls in any supergravity theory. Similar considerations hold here also. Moreover, it is shown that the worldvolume of any magnetic brane --- of which the domain walls are a specific example --- can be generalised in precisely the same way. The general class of supersymmetric solutions have gravitational instantons as their spatial sections. Some mention is made of the worldvolume solitons of such branes.Comment: 26 pages, LaTe

Bethe ansatz for the XXX-S chain with non-diagonal open boundaries

We consider the algebraic Bethe ansatz solution of the integrable and isotropic XXX-S Heisenberg chain with non-diagonal open boundaries. We show that the corresponding K-matrices are similar to diagonal matrices with the help of suitable transformations independent of the spectral parameter. When the boundary parameters satisfy certain constraints we are able to formulate the diagonalization of the associated double-row transfer matrix by means of the quantum inverse scattering method. This allows us to derive explicit expressions for the eigenvalues and the corresponding Bethe ansatz equations. We also present evidences that the eigenvectors can be build up in terms of multiparticle states for arbitrary S.Comment: 62 page

On the Inverse Scattering Method for Integrable PDEs on a Star Graph

© 2015, Springer-Verlag Berlin Heidelberg. We present a framework to solve the open problem of formulating the inverse scattering method (ISM) for an integrable PDE on a star-graph. The idea is to map the problem on the graph to a matrix initial-boundary value (IBV) problem and then to extend the unified method of Fokas to such a matrix IBV problem. The nonlinear Schrödinger equation is chosen to illustrate the method. The framework unifies all previously known examples which are recovered as particular cases. The case of general Robin conditions at the vertex is discussed: the notion of linearizable initial-boundary conditions is introduced. For such conditions, the method is shown to be as efficient as the ISM on the full-line

Statistics for Fission-Track Thermochronology

This chapter introduces statistical tools to extract geologically meaningful information from fission-track (FT) data using both the external detector and LA-ICP-MS methods. The spontaneous fission of 238U is a Poisson process resulting in large single-grain age uncertainties. To overcome this imprecision, it is nearly always necessary to analyse multiple grains per sample. The degree to which the analytical uncertainties can explain the observed scatter of the single-grain data can be visually assessed on a radial plot and objectively quantified by a chi-square test. For sufficiently low values of the chi-square statistic (or sufficiently high p values), the pooled age of all the grains gives a suitable description of the underlying ‘true’ age population. Samples may fail the chi-square test for several reasons. A first possibility is that the true age population does not consist of a single discrete age component, but is characterised by a continuous range of ages. In this case, a ‘random effects’ model can constrain the true age distribution using two parameters: the ‘central age’ and the ‘(over)dispersion’. A second reason why FT data sets might fail the chi-square test is if they are underlain by multimodal age distributions. Such distributions may consist of discrete age components, continuous age distributions, or a combination of the two. Formalised statistical tests such as chi-square can be useful in preventing overfitting of relatively small data sets. However, they should be used with caution when applied to large data sets (including length measurements) which generate sufficient statistical ‘power’ to reject any simple yet geologically plausible hypothesis

A new type of highly-vaporized microtektite from the Transantarctic Mountains

We report on the discovery of microtektites (microscopic impact glass spherules) in a glacial moraine near Larkman Nunatak in the Transantarctic Mountains, Antarctica. The microtektites were identified based on their physical and chemical properties. Major and trace element compositions of the particles suggest that they may be related to the Australasian strewn field. This would further extend the current strewn field ∼800 km southward. Depletion in volatiles and enrichment in refractory elements in Larkman Nunatak microtektites fit the volatilization trend defined by Australasian microtektites, suggesting that they may represent a new highly vapor fractionated end-member thereof. This observation is supported by their low vesicularity and absence of mineral inclusions. This discovery has significant implications for the formation of microtektites (i.e. their evolution with respect to the distance from the source crater). Finally, the discovery of potentially old (i.e. 0.8 Ma) microtektites in moraine has implications for the stability of the East Antarctic Ice Sheet in the Larkman Nunatak area over the last ∼1 Ma and, as a consequence, the high efficiency of such moraines as traps for other extraterrestrial materials (e.g. micrometeorites and meteoritic ablation debris)

Evaluation of sesamum gum as an excipient in matrix tablets

In developing countries modern medicines are often beyond the affordability of the majority of the population. This is due to the reliance on expensive imported raw materials despite the abundance of natural resources which could provide an equivalent or even an improved function. The aim of this study was to investigate the potential of sesamum gum (SG) extracted from the leaves of Sesamum radiatum (readily cultivated in sub-Saharan Africa) as a matrix former. Directly compressed matrix tablets were prepared from the extract and compared with similar matrices of HPMC (K4M) using theophylline as a model water soluble drug. The compaction, swelling, erosion and drug release from the matrices were studied in deionized water, 0.1 N HCl (pH 1.2) and phosphate buffer (pH 6.8) using USP apparatus II. The data from the swelling, erosion and drug release studies were also fitted into the respective mathematical models. Results showed that the matrices underwent a combination of swelling and erosion, with the swelling action being controlled by the rate of hydration in the medium. SG also controlled the release of theophylline similar to the HPMC and therefore may have use as an alternative excipient in regions where Sesamum radiatum can be easily cultivated

Velocity-space sensitivity of the time-of-flight neutron spectrometer at JET

The velocity-space sensitivities of fast-ion diagnostics are often described by so-called weight functions. Recently, we formulated weight functions showing the velocity-space sensitivity of the often dominant beam-target part of neutron energy spectra. These weight functions for neutron emission spectrometry (NES) are independent of the particular NES diagnostic. Here we apply these NES weight functions to the time-of-flight spectrometer TOFOR at JET. By taking the instrumental response function of TOFOR into account, we calculate time-of-flight NES weight functions that enable us to directly determine the velocity-space sensitivity of a given part of a measured time-of-flight spectrum from TOFOR