49 research outputs found

    Predicting evolution and visualizing high-dimensional fitness landscapes

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    The tempo and mode of an adaptive process is strongly determined by the structure of the fitness landscape that underlies it. In order to be able to predict evolutionary outcomes (even on the short term), we must know more about the nature of realistic fitness landscapes than we do today. For example, in order to know whether evolution is predominantly taking paths that move upwards in fitness and along neutral ridges, or else entails a significant number of valley crossings, we need to be able to visualize these landscapes: we must determine whether there are peaks in the landscape, where these peaks are located with respect to one another, and whether evolutionary paths can connect them. This is a difficult task because genetic fitness landscapes (as opposed to those based on traits) are high-dimensional, and tools for visualizing such landscapes are lacking. In this contribution, we focus on the predictability of evolution on rugged genetic fitness landscapes, and determine that peaks in such landscapes are highly clustered: high peaks are predominantly close to other high peaks. As a consequence, the valleys separating such peaks are shallow and narrow, such that evolutionary trajectories towards the highest peak in the landscape can be achieved via a series of valley crossingsComment: 12 pages, 7 figures. To appear in "Recent Advances in the Theory and Application of Fitness Landscapes" (A. Engelbrecht and H. Richter, eds.). Springer Series in Emergence, Complexity, and Computation, 201

    The Physics of the B Factories

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    The BaBar detector: Upgrades, operation and performance

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    Contains fulltext : 121729.pdf (preprint version ) (Open Access

    Evolutionary perspectives on salary dispersion within firms

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    Behavioral economics, Relative fitness, Egalitarianism, Evolutionary psychology, Anthropology, Trans disciplinary, Compensation, Sex differences, Age, Labor unions, J31, D31, M52, Z10,

    Erratum: Measurement of the absolute branching fractions for D-S(-) -> l(-)(nu)over-bar(l) and extraction of the decay constant f(Ds) (vol 82, 091103, 2010)

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