2,743 research outputs found
Scanning Electron Microscopy Study of Particles Generated by Laser Damage of Aluminum Surfaces
A high intensity iodine laser (1.315 μm wavelength) was used to study laser-surface damage in vacuum. A 22mm diameter laser beam containing 3.9 J of energy was focused to a 1 mm spot on an aluminum plate mounted in a vacuum chamber. The laser pulse width was 7 μs (FWHM). A copper strip mounted on a quarter circle plate 3.5 cm from the laser spot was used to collect particles ejected from the surface. A scanning electron microscope (SEM) was used to measure the size and spatial distribution of the particles collected on the copper strip. It was found that aluminum droplets were ejected from the crater formed by the laser pulse. The particle sizes ranged from 0.25 to 45 μm in diameter. The peak of the particle size distribution occurred at 1 μm diameter. The maximum spatial distribution of droplets occurred at near 47° from the normal to the target surface. Measurement of the mass lost by the target plate and the volume of aluminum removed from the craters showed that most of the aluminum ejected from the craters remained on the target surface. SEM examination of the surface adjacent to the craters showed that most of the ejected aluminum was liquid splattered around the crater. The particle size and spatial distributions are considered preliminary because droplets smaller than 0.25 μm could not be detected and the copper collector strip was examined in only six areas corresponding to six emission angles
Conservation implications of sea turtle nesting trends: elusive recovery of a globally important loggerhead population
Abstract Understanding population status and trends is important for developing and evaluating management and conservation actions for threatened species. Monitoring population status of marine organisms is especially challenging. Because sea turtles come ashore to lay their eggs and nests are easily counted, these counts are commonly used as an index of abundance and population trends. Nest counts do not provide a direct index of adult female population abundance because females typically lay more than one nest per year and most do not reproduce every year. This study attempts for the first time to investigate the likelihood that observed fluctuations of nest counts represent inter‐annual changes of the adult female population by accounting for uncertainty in reproductive rate parameters. We analyzed 30 yr of reproductive data from the largest nesting loggerhead sea turtle population worldwide, breeding in Florida (USA), and for the three Recovery Units and seven Management Units therein. Nest counts followed a general non‐monotonic trend with wide fluctuations that corresponded to decreasing and increasing trends during short intervals. When we accounted for uncertainty in both clutch frequency and remigration interval, there was no evidence for an increasing or a declining trend in the breeding female population across the entire period. Despite extensive conservation efforts and protections for loggerheads in Florida and the wider USA, we did not find evidence of a strong population recovery. We recommend maintaining a high level of protection, addressing persistent anthropogenic threats, continued collection of rigorous nest‐count data, and monitoring reproductive parameters to better link nest counts to adult female population abundance. Our results demonstrate the need for caution in using nest counts as a direct proxy for adult female population status, as it may lead to unsupported conclusions potentially detrimental to conservation. Therefore, we recommend to always translating nest trends to at least adult female trends, including uncertainty in reproductive parameters. Our approach can be exported to other populations, even where reproductive parameters are not available. Applying high parameter uncertainty obtained from other populations can help identifying unequivocal population changes; that is, nest trends unlikely justified by uncertainty and poor knowledge of reproductive parameters
Nearly degenerate two-beam coupling in photorefractive crystals with two species of movable carriers
Two-beam intensity coupling is calculated for photorefractive crystals with two types of movable charge carrier in the undepleted-pump approximation. The analytical expressions are derived for the temporal evolution of the space-charge field; for weak coupling they are used for calculation of the transmitted beam intensities. The results of the calculation are compared with the experimental observations in photorefractive tin hypothiodiphosphate (Sn 2 P 2 S 6 ). All experimental data are in reasonable quantitative agreement with the calculations. © 1998 Optical Society of America [S0740-3224(98
Constrained 2-D/3-D Registration for Motion Compensation in AFib Ablation Procedures
Abstract. Fluoroscopic overlay images rendered from pre-operative vol-umetric data can provide additional guidance for physicians during catheter ablation procedures for treatment of atrial fibrillation (AFib). As these overlay images are compromised by cardiac and respiratory motion, mo-tion compensation methods have been proposed. The approaches so far either require simultaneous biplane imaging for 3-D motion compensa-tion or, in case of mono-plane X-ray imaging, provide only a limited 2-D functionality. To overcome the downsides of the previously suggested methods, we propose a new approach that facilitates full 3-D motion compensation even if only mono-plane X-ray views are available. To this end, we use constrained model-based 2-D/3-D registration to track a circumferential mapping catheter which is commonly used during AFib catheter ablation procedures. Our approach yields an average 2-D track-ing error of 0.6 mm and an average 3-D tracking error of 2.1 mm.
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Turbulent flow at 190 m height above London during 2006-2008: A climatology and the applicability of similarity theory
Flow and turbulence above urban terrain is more complex than above rural terrain, due to the different momentum and heat transfer characteristics that are affected by the presence of buildings (e.g. pressure variations around buildings). The applicability of similarity theory (as developed over rural terrain) is tested using observations of flow from a sonic anemometer located at 190.3 m height in London, U.K. using about 6500 h of data. Turbulence statistics—dimensionless wind speed and temperature, standard deviations and correlation coefficients for momentum and heat transfer—were analysed in three ways. First, turbulence statistics were plotted as a function only of a local stability parameter z/Λ (where Λ is the local Obukhov length and z is the height above ground); the σ_i/u_* values (i = u, v, w) for neutral conditions are 2.3, 1.85 and 1.35 respectively, similar to canonical values. Second, analysis of urban mixed-layer formulations during daytime convective conditions over London was undertaken, showing that atmospheric turbulence at high altitude over large cities might not behave dissimilarly from that over rural terrain. Third, correlation coefficients for heat and momentum were analyzed with respect to local stability. The results give confidence in using the framework of local similarity for turbulence measured over London, and perhaps other cities. However, the following caveats for our data are worth noting: (i) the terrain is reasonably flat, (ii) building heights vary little over a large area, and (iii) the sensor height is above the mean roughness sublayer depth
Identification of a Bacterial Type III Effector Family with G Protein Mimicry Functions
SummaryMany bacterial pathogens use the type III secretion system to inject “effector” proteins into host cells. Here, we report the identification of a 24 member effector protein family found in pathogens including Salmonella, Shigella, and enteropathogenic E. coli. Members of this family subvert host cell function by mimicking the signaling properties of Ras-like GTPases. The effector IpgB2 stimulates cellular responses analogous to GTP-active RhoA, whereas IpgB1 and Map function as the active forms of Rac1 and Cdc42, respectively. These effectors do not bind guanine nucleotides or have sequences corresponding the conserved GTPase domain, suggesting that they are functional but not structural mimics. However, several of these effectors harbor intracellular targeting sequences that contribute to their signaling specificities. The activities of IpgB2, IpgB1, and Map are dependent on an invariant WxxxE motif found in numerous effectors leading to the speculation that they all function by a similar molecular mechanism
Cryo-balloon reconstruction from two views
Atrial fibrillation is a major cause of stroke. Its treatment is performed under fluoroscopic image guidance. Augmented fluoroscopy has become a useful tool during the ablation pro-cedure for navigation under X-ray. Unfortunately, current navigation systems do not provide tools to localize and visu-alize a cryo-balloon catheters in 3-D. This is why we present a new approach to reconstruct the cryo-ballon catheter, mod-eled as a sphere, from two views. The reconstruction result can then be overlayed onto live fluoroscopic images during the procedure. In simulation studies, we compared our tech-nique to a reference method. While both methods worked equally well on noise-free data, we found our method more reliable if the input data was affected by noise. For example, in the presence of noise with a standard deviation of 4 mm, our maximum 3-D reconstruction error was less than 1 mm
Modelling chemistry in the nocturnal boundary layer above tropical rainforest and a generalised effective nocturnal ozone deposition velocity for sub-ppbv NOx conditions
Measurements of atmospheric composition have been made over a remote rainforest landscape. A box model has previously been demonstrated to model the observed daytime chemistry well. However the box model is unable to explain the nocturnal measurements of relatively high [NO] and [O3], but relatively low observed [NO2]. It is shown that a one-dimensional (1-D) column model with simple O3 -NOx chemistry and a simple representation of vertical transport is able to explain the observed nocturnal concentrations and predict the likely vertical profiles of these species in the nocturnal boundary layer (NBL). Concentrations of tracers carried over from the end of the night can affect the atmospheric chemistry of the following day. To ascertain the anomaly introduced by using the box model to represent the NBL, vertically-averaged NBL concentrations at the end of the night are compared between the 1-D model and the box model. It is found that, under low to medium [NOx] conditions (NOx <1 ppbv), a simple parametrisation can be used to modify the box model deposition velocity of ozone, in order to achieve good agreement between the box and 1-D models for these end-of-night concentrations of NOx and O3. This parametrisation would could also be used in global climate-chemistry models with limited vertical resolution near the surface. Box-model results for the following day differ significantly if this effective nocturnal deposition velocity for ozone is implemented; for instance, there is a 9% increase in the following day’s peak ozone concentration. However under medium to high [NOx] conditions (NOx > 1 ppbv), the effect on the chemistry due to the vertical distribution of the species means no box model can adequately represent chemistry in the NBL without modifying reaction rate constants
Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation
Hsp90 is a highly conserved molecular chaperone that is involved in modulating a multitude of cellular processes. In this study, we identify a function for the chaperone in RNA processing and maintenance. This functionality of Hsp90 involves two recently identified interactors of the chaperone: Tah1 and Pih1/Nop17. Tah1 is a small protein containing tetratricopeptide repeats, whereas Pih1 is found to be an unstable protein. Tah1 and Pih1 bind to the essential helicases Rvb1 and Rvb2 to form the R2TP complex, which we demonstrate is required for the correct accumulation of box C/D small nucleolar ribonucleoproteins. Together with the Tah1 cofactor, Hsp90 functions to stabilize Pih1. As a consequence, the chaperone is shown to affect box C/D accumulation and maintenance, especially under stress conditions. Hsp90 and R2TP proteins are also involved in the proper accumulation of box H/ACA small nucleolar RNAs
Measurement of the cross-section and charge asymmetry of bosons produced in proton-proton collisions at TeV with the ATLAS detector
This paper presents measurements of the and cross-sections and the associated charge asymmetry as a
function of the absolute pseudorapidity of the decay muon. The data were
collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with
the ATLAS experiment at the LHC and correspond to a total integrated luminosity
of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements
varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the
1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured
with an uncertainty between 0.002 and 0.003. The results are compared with
predictions based on next-to-next-to-leading-order calculations with various
parton distribution functions and have the sensitivity to discriminate between
them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables,
submitted to EPJC. All figures including auxiliary figures are available at
https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13
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