80 research outputs found
An Ultra Fast Image Generator (UFig) for wide-field astronomy
Simulated wide-field images are becoming an important part of observational
astronomy, either to prepare for new surveys or to test measurement methods. In
order to efficiently explore vast parameter spaces, the computational speed of
simulation codes is a central requirement to their implementation. We introduce
the Ultra Fast Image Generator (UFig) which aims to bring wide-field imaging
simulations to the current limits of computational capabilities. We achieve
this goal through: (1) models of galaxies, stars and observational conditions,
which, while simple, capture the key features necessary for realistic
simulations, and (2) state-of-the-art computational and implementation
optimizations. We present the performances of UFig and show that it is faster
than existing public simulation codes by several orders of magnitude. It allows
us to produce images more quickly than SExtractor needs to analyze them. For
instance, it can simulate a typical 0.25 deg^2 Subaru SuprimeCam image (10k x
8k pixels) with a 5-sigma limiting magnitude of R=26 in 30 seconds on a laptop,
yielding an average simulation time for a galaxy of 30 microseconds. This code
is complementary to end-to-end simulation codes and can be used as a fast,
central component of observational methods relying on simulations.Comment: Submitted to Astronomy and Computing. 13 pages, 9 figure
Meta-analysis of environmental contamination by phtalates
Introduction: Phthalate Acid Esters (PAE), commonly named Phthalates, are toxics classified as endocrine-disrupting compounds; they are primarily used as additives to improve the flexibility in polyvinyl chloride. Occurrence: Many studies have reported the occurrence of phthalates in different environmental matrices, however none of these studies has yet establish a complete overview for those compounds in the water cycle within an urban environment. This review summarizes PAE concentrations for all environmental media throughout the water cycle, from atmosphere to receiving waters. Once the occurrences of compounds have been evaluated for each environmental compartment (urban wastewater, wastewater treatment plants, atmosphere and the natural environment), data are reviewed in order to identify the fate of PAE in the environment and establish whether geographical and historical trends exist. Indeed, geographical and historical trends appear between Europe and other countries such as USA/Canada and China, however they remain location-dependent. Discussion: This study aimed at identifying both the correlations existing between environmental compartments and the processes influencing the fate and transport of these contaminants into the environment. In Europe, the concentrations measured in waterways today represent the background level of contamination, which provides evidence of a past diffuse pollution. In contrast, an increasing trend has actually been observed for developing countries, especially for China
Optimal capture of non-Gaussianity in weak lensing surveys: power spectrum, bispectrum and halo counts
We compare the efficiency of weak lensing-selected galaxy clusters counts and
of the weak lensing bispectrum at capturing non-Gaussian features in the dark
matter distribution. We use the halo model to compute the weak lensing power
spectrum, the bispectrum and the expected number of detected clusters, and
derive constraints on cosmological parameters for a large, low systematic weak
lensing survey, by focusing on the - plane and on the dark
energy equation of state. We separate the power spectrum into the resolved and
the unresolved parts of the data, the resolved part being defined as detected
clusters, and the unresolved part as the rest of the field. We consider four
kinds of clusters counts, taking into account different amount of information :
signal-to-noise ratio peak counts; counts as a function of clusters' mass;
counts as a function of clusters' redshift; and counts as a function of
clusters' mass and redshift. We show that when combined with the power
spectrum, those four kinds of counts provide similar constraints, thus allowing
one to perform the most direct counts, signal-to-noise peaks counts, and get
percent level constraints on cosmological parameters. We show that the weak
lensing bispectrum gives constraints comparable to those given by the power
spectrum and captures non-Gaussian features as well as clusters counts, its
combination with the power spectrum giving errors on cosmological parameters
that are similar to, if not marginally smaller than, those obtained when
combining the power spectrum with cluster counts. We finally note that in order
to reach its potential, the weak lensing bispectrum must be computed using all
triangle configurations, as equilateral triangles alone do not provide useful
information.Comment: Matches ApJ-accepted versio
Combined analysis of weak lensing and X-ray blind surveys
We present a joint weak lensing and X-ray analysis of 4 deg from the
CFHTLS and XMM-LSS surveys. Our weak lensing analysis is the first analysis of
a real survey using shapelets, a new generation weak lensing analysis method.
We create projected mass maps of the images, and extract 6
weak-lensing-detected clusters of galaxies. We show that their counts can be
used to constrain the power spectrum normalisation for . We show that despite the large
scatter generally observed in the M-T relation derived from lensing masses,
tight constraints on both its slope and normalisation can be obtained
with a moderate number of sources provided that the covered mass range is large
enough. Adding clusters from Bardeau et al. (2007) to our sample, we measure
. Although they are
dominated by shot noise and sample variance, our measurements are consistent
with currently favoured values, and set the stage for future surveys. We thus
investigate the dependence of those estimates on survey size, depth, and
integration time, for joint weak lensing and X-ray surveys. We show that deep
surveys should be dedicated to the study of the physics of clusters and groups
of galaxies. For a given exposure time, wide surveys provide a larger number of
detected clusters and are therefore preferred for the measurement of
cosmological parameters such as and . We show that a wide
survey of a few hundred square degrees is needed to improve upon current
measurements of these parameters. More ambitious surveys covering 7000 deg
will provide the 1% accuracy in the estimation of the power spectrum and the
M-T relation normalisations.Comment: MNRAS in press Matches accepted version. References update
New 8-nitroquinolinone derivative displaying submicromolar in vitro activities against both Trypanosoma brucei and cruzi
International audienceAn antikinetoplastid pharmacomodulation study was conducted at position 6 of the 8-nitroquinolin-2(1H)-one pharmacophore. Fifteen new derivatives were synthesized and evaluated in vitro against L. infantum, T. brucei brucei, and T. cruzi, in parallel with a cytotoxicity assay on the human HepG2 cell line. A potent and selective 6-bromo-substituted antitrypanosomal derivative 12 was revealed, presenting EC50 values of 12 and 500 nM on T. b. brucei trypomastigotes and T. cruzi amastigotes respectively, in comparison with four reference drugs (30 nM ≤ EC50 ≤ 13 μM). Moreover, compound 12 was not genotoxic in the comet assay and showed high in vitro microsomal stability (half life >40 min) as well as favorable pharmacokinetic behavior in the mouse after oral administration. Finally, molecule 12 (E° = −0.37 V/NHE) was shown to be bioactivated by type 1 nitroreductases, in both Leishmania and Trypanosoma, and appears to be a good candidate to search for novel antitrypanosomal lead compounds
Cold atoms in space: community workshop summary and proposed road-map
We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies
Cold atoms in space: community workshop summary and proposed road-map
We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies.publishedVersio
Cold atoms in space: community workshop summary and proposed road-map
We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies
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Cold atoms in space: community workshop summary and proposed road-map
We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies
MICROSCOPE mission: first results of a space test of the equivalence principle
According to the weak equivalence principle, all bodies should fall at the same rate in a gravitational field. The MICROSCOPE satellite, launched in April 2016, aims to test its validity at the 10−15 precision level, by measuring the force required to maintain two test masses (of titanium and platinum alloys) exactly in the same orbit. A nonvanishing result would correspond to a violation of the equivalence principle, or to the discovery of a new long-range force. Analysis of the first data gives δ(Ti,Pt)=[−1±9(stat)±9(syst)]×10−15 (1σ statistical uncertainty) for the titanium-platinum Eötvös parameter characterizing the relative difference in their free-fall accelerations
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