1,640 research outputs found

    Genetic characterization of seedling and adult plant resistance against three rust diseases in the 22nd SAWSN CIMMYT Nursery

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    Relatório de estágio do mestrado em Ensino da Educação Física nos Ensinos Básico e Secundário, apresentado à Faculdade de Ciências do Desporto e Educação Física da Universidade de CoimbraEste relatório final surge a conclusão de uma formação de dois anos neste mestrado. O Estágio Pedagógico foi realizado na Escola Secundária de Anadia junto da turma D do 9º ano de escolaridade, durante o ano lectivo de 2013/14. O presente trabalho, pretende relatar e refletir sobre os procedimentos adotados em três processos por mim considerados fundamentais no processo ensino-aprendizagem, o planeamento; a realização e a avaliação. Ao longo do ano lectivo a reflexão constante sobre a prática pedagógica permitiu que me torna-se um professor em constante evolução, absorvendo a informação e tendo uma postura critica em relação a este processo. Com este relatório pretendo demonstrar o processo desenvolvido ao longo desta jornada. Um dos principais desfechos que retiro deste processo é a necessidade de ensinar e promover a aprendizagem adequada a todos os alunos. Deste o aluno que tem excesso de peso, ao que tem Necessidades Educativas Especiais, ao que não gosta de educação física, estre outros perfis. Se lhes for apresentado um ambiente adequado às suas necessidades todos eles serão munidos de uma importante bagagem. O estágio pedagógico promove a aquisição de um conjunto de saberes, de atitudes práticas e resolução de problemas pedagógicos, que servirão como base de sustentação para a integração futura no ensino e também será transversal a outras actividades ligadas ao desporto e à promoção de saúde. Por último, será abordado o tema: grupos de nível em Educação Física, apresentando como exemplo a turma do 9ºD. Que se foi confrontada ao longo do ano lectivos pela homo e heterogeneidade nos grupos formados para a aula. This final report is the conclusion of a two-year training in this Masters Degree. The Pedagogical Internship was conducted in Escola Secundária de Anadia with class D of the 9th grade during the school year 2013/14. The present study aims to report and reflect on the procedures adopted in the three cases, that i considered fundamental, teaching-learning process, planning; the implementation and evaluation. During the school year, constant reflexion about pedagogical act allow me toi became a teacher in constant improvement, absorbing all the information with na critic posture about the teaching. With this report i pretend show all the process developed during this long journey. One of the principals knowledges i reatret from this process is the need of teaching and promote na learning suitable for all students. From the student who have overweight, the one who has Special Educational Needs, the student who don’t like physical education, until the other students profile, if we gave them an suitable environment to their needs, al og them will todos eles will be provided with an important baggage. The Pedagogical Internship promotes the acquisition of an a aquisição de a set of knowledge, with practices and attitudes for solving pedagogical problems, to serve as a support base for future integration in teaching and will also be cross-linked to other activities for sport and health promotion.. Last but not least, will be approach a theme: Group levels on physical Education class, using as an example the class D from the 9th grade . Who was faced throughout the school year by the homo-and heterogeneity in groups formed for class

    Revisiting old landraces of wheat for stem rust resistance

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    Identification of markers linked with stem rust resistance genes Sr33 and Sr45

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    Measurement of the t(t)over-bar production cross section in the dilepton channel in pp collisions at √s=8 TeV

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    The top-antitop quark (t (t) over bar) production cross section is measured in proton-proton collisions at root s = 8 TeV with the CMS experiment at the LHC, using a data sample corresponding to an integrated luminosity of 5.3 fb(-1). The measurement is performed by analysing events with a pair of electrons or muons, or one electron and one muon, and at least two jets, one of which is identified as originating from hadronisation of a bottom quark. The measured cross section is 239 +/- 2 (stat.) +/- 11 (syst.) +/- 6 (lum.) pb, for an assumed top-quark mass of 172.5 GeV, in agreement with the prediction of the standard model

    Long-Term Impact of Radiation on the Stem Cell and Oligodendrocyte Precursors in the Brain

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    Background. The cellular basis of long term radiation damage in the brain is not fully understood. Methods and Findings. We administered a dose of 25Gy to adult rat brains while shielding the olfactory bulbs. Quantitative analyses were serially performed on different brain regions over 15 months. Our data reveal an immediate and permanent suppression of SVZ proliferation and neurogenesis. The olfactory bulb demonstrates a transient but remarkable SVZ-independent ability for compensation and maintenance of the calretinin interneuron population. The oligodendrocyte compartment exhibits a complex pattern of limited proliferation of NG2 progenitors but steady loss of the oligodendroglial antigen O4. As of nine months post radiation, diffuse demyelination starts in all irradiated brains. Counts of capillary segments and length demonstrate significant loss one day post radiation but swift and persistent recovery of the vasculature up to 15 months post XRT. MRI imaging confirms loss of volume of the corpus callosum and early signs of demyelination at 12 months. Ultrastructural analysis demonstrates progressive degradation of myelin sheaths with axonal preservation. Areas of focal necrosis appear beyond 15 months and are preceded by widespread demyelination. Human white matter specimens obtained post-radiation confirm early loss of oligodendrocyte progenitors and delayed onset of myelin sheath fragmentation with preserved capillaries. Conclusions. This study demonstrates that long term radiation injury is associated with irreversible damage to the neural stem cell compartment in the rodent SVZ and loss of oligodendrocyte precursor cells in both rodent and human brain. Delayed onset demyelination precedes focal necrosis and is likely due to the loss of oligodendrocyte precursor

    Micelles as Delivery Vehicles for Oligofluorene for Bioimaging

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    With the successful development of organic/polymeric light emitting diodes, many organic and polymeric fluorophores with high quantum efficiencies and optical stability were synthesized. However, most of these materials which have excellent optical properties are insoluble in water, limiting their applications in biological fields. Herein, we used micelles formed from an amino-group-containing poly(ε-caprolactone)-block-poly(ethylene glycol) (PCL-b-PEG-NH2) to incorporate a hydrophobic blue emitter oligofluorene (OF) to enable its application in biological conditions. Although OF is completely insoluble in water, it was successfully transferred into aqueous solutions with a good retention of its photophysical properties. OF exhibited a high quantum efficiency of 0.84 in a typical organic solvent of tetrahydrofuran (THF). In addition, OF also showed a good quantum efficiency of 0.46 after being encapsulated into micelles. Two cells lines, human glioblastoma (U87MG) and esophagus premalignant (CP-A), were used to study the cellular internalization of the OF incorporated micelles. Results showed that the hydrophobic OF was located in the cytoplasm, which was confirmed by co-staining the cells with nucleic acid specific SYTO 9, lysosome specific LysoTracker Red®, and mitochondria specific MitoTracker Red. MTT assay indicated non-toxicity of the OF-incorporated micelles. This study will broaden the application of hydrophobic functional organic compounds, oligomers, and polymers with good optical properties to enable their applications in biological research fields

    Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector

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    A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fb−1 of s=7  TeV \sqrt{s}=7\;\mathrm{TeV} proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan β < 40
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