6 research outputs found
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
- Author
- Liza
- - AP-HP) Bertrand Dousset (H\uf4pital Cochin
- - APHP) Anne Thomin (H\uf4pital Trousseau
- - ASST Rhodense) Carlo Corbellin (Ospedale Di Rho
- - NYU Winthrop Hospital) Amir H Sohail (NYU Langone Health
- - Xarxa Assistencial Universit\ue0ria de Manresa) Pablo Collera Ormazabal (Fundaci\uf3 Althaia
- / Columbia University Medical Center) Miriam Callahan (NewYork-Presbyterian
- 3 University Hospital) Bridget Egan (Tallaght
- 4 Lapolla Pierfrancesco
- 5 Spain: Eduardo E Rubio Susana Henriques (Hospital Garcia de Orta).
- 6 G\uf3mez Marcos
- \u2013 IRCCS Francesca Gaino (Humanitas Clinical and Research Center
- \u2013 Italy) 20089 Rozzano (MI)
- \uc1ngel Hern\ue1ndez Bartolom\ue9 Miguel
- A Aaraj Mahmoud
- A Ayeni Funbi
- A Bass Gary
- A Benson Ruth
- A Bozkurt Mehmet
- A Breen Kerry
- A Breen Kerry
- A Breen Kerry
- A Callcut Rachael
- A Chung Eric
- A Coughlin Patrick
- A de Gheldere Charles
- A De Marchi Joshua
- A Elliott Jessie
- A Fahey Brian
- A Griffiths Ewen
- A Griffiths Ewen
- A Griffiths Ewen
- A Guariglia Claudio
- A Hirji Sameer
- A Khalefa Mohamed
- A Marra (Fondazione Policlinico Universitario Agostino Gemelli) Angelo
- A Nguyen (Frankfurt University Hospital Truong
- A Olson (Duke University Medical Center) Steven
- A Raptis Dimitri
- A Rollett Rebecca
- A Saeed Samerah
- A Salama Hiba
- A Salamah Abdulrauf
- A Schnitzbauer Andreas
- A Schnitzbauer Andreas
- A Singh Aminder
- A Stevens Kent
- A Stylianides Nicholas
- A Thaha Mohamed
- A Vega (12 de Octubre University Hospital) Viviana
- A Vivas Alfredo
- A Zappa Marco
- Abate Emmanuele
- Abdalaziz (Gloucestershire Royal Hospital) Hossam
- Abdelkarim Mostafa
- Abdou Hossam
- Aboelkassem-Ibrahim Ahmad
- Abuown Ala
- Acebes-Garcia Fernando
- Acharya Metesh
- Adamina Michel
- Addae-Boateng Emmanuel
- Adolfo Pisanu (Cagliari University Hospital) Mauro Podda
- Aftab Raiyyan
- AG Moir John
- Agarwal Arnav
- AH Ibrahim Mohamed
- Aitken (Queen Elizabeth University Hospital) Emma
- Al-Azzawi Marwa
- Al-Embideen Somya
- Al-Sukaini Ahmad
- Alakaloko Felix
- Alam (Heartlands Hospital) Ruhina
- Alameer Ehab
- Alderson Derek
- Ali Mohamed Ali (Queen Elizabeth Hospital King's Lynn) Inthekab
- Aliyeva (Acibadem Mehmet Ali Aydinlar University Zumrud
- Aljanadi Firas
- Almasri Murad
- Alonso Poza (Hospital Universitario del Sureste) Alfredo
- Alonso-Ortu\uf1o Paula
- Alser Osaid
- Alser Osaid
- Alser Osaid
- Altintoprak (Sakarya University Faculty of Medicine) Fatih
- Amalina Che Bakri Nur
- Amjad Rabbia
- Anania Gabriele
- and Westminster Hospital NHS FT and Imperial College London) Chelsea
- Andabaka Tatjana
- Andrea Pisani Ceretti (ASST Santi Paolo e Carlo) Nicol\uf2 M Mariani
- Angelou Dimitrios
- Anita Volpe (New York Presbyterian Queens) Stephen Merola
- Annamalai Seethalakshmi
- Annessi Valerio
- Anthoney James
- Anuradha R Bhama (Rush University Medical Center) Alfonso Torquati
- Anwar Sibtain
- Aragon-Chamizo Juan
- Ardito Antonella
- Arigoni Michele
- Armao Teodora
- Arminio (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia) Armando
- Armstrong Lara
- Asaad Peter
- Ashcroft James
- Ashmore Christopher
- Asqalan Ahmad
- Asti (IRCCS Policlinico San Donato Emanuele
- Aubry Emmanuelle
- Aytac Erman
- Ayuso-Herrera Esther
- Azerbaijan:Elgun Samadov Joana FF Simoes (Chair). 2 Collaborators: (denotes Local Principal Investigator) Algeria: Faraj S Almaadany (\uc9tablissement Hospitalier Sp\ue9cialis\ue9 en Canc\ue9rologie - Centre Pierre-et- Marie-Curie).
- B Avellana Rocio
- B Catton Andrew
- B Fonsi Giovanni
- B Hing Caroline
- B O'Meara Lindsay
- B Schaffer Kathryn
- B Yousuf (Tobruk Medical Center) Farhat
- B\ue0mbina (Fabrizio Spaziani Hospital Fabrizio
- Bailon-Cuadrado (Hospital Universitario R\uedo Hortega) Martin
- Baldi Caterina
- Baldini Edoardo
- Baldo (Ospedale Santa Corona Stefano
- Ballabio Michele
- Baloyiannis Ioannis
- Baltazar Gerard
- Bandiera Alessandro
- Barlow Emma
- Barmasse (Ospedale Regionale Umberto Parini) Roberto
- Barmpagianni Christina
- Baronio (Policlinico San Pietro) Gianluca
- Barra Fabio
- Bartholomew's Hospital) St
- Bartsch Anne-Marie
- Basgaran Amedra
- Basha Amr
- Bashkirova (North Middlesex University Hospital) Varvara
- Bastazza Marco
- BB Sullivan (The Royal London Hospital) Tom
- Beak Philip
- Belcher Elizabeth
- Belgium: Gabrielle H van Ramshorst Sevda Jafarova (Leyla Medical Center).
- Beltr\ue1n de Heredia Juan
- Belvedere Angela
- Ben\uedtez-Linero Inmaculada
- Benjamin Franklin) Campus
- Bergeat Damien
- Bernasconi Matteo
- Bhalla Ashish
- Bhangu Aneel
- Bianco Federica
- Bisagni Pietro
- BJ Borgstein Alexander
- Blake (Southport and Formby District General Hospital) Iain
- Blanco-Colino Ruth
- Blazquez-Martin (Hospital Principe De Asturias) Alma
- Boal Matthew
- Bologna) Ausl
- Bonavina Giulia
- Bonavina Luigi
- Bond-Smith Giles
- Booth (Freeman Hospital) Karen
- Borges Filipe
- Borghi Felice
- Borja De Lacy (Hospital Clinic Barcelona) F
- Bourke Grainne
- Boyle Emily
- Brachini Gioia
- Brain Jessie
- Brar Amanpreet
- Breckles Lisa
- Brendan L Skelly (Altnagelvin Area Hospital) Catherine Rossborough
- Brianza) Carate
- Brixton Genevieve
- Bruzzaniti Placido
- Bueser Teofila
- Burnside Nathan
- C Bosanquet David
- C Brown (Manchester University NHS Foundation Trust Benjamin
- C De Souza Anthony
- C Glasbey James
- C Glasbey James
- C Hopkins James
- C Lauscher Johannes
- C McIntyre Robert
- C Mckay Siobhan
- C Neary Paul
- C Nugent III William
- C Rodriguez-Sanjuan (Marqu\ue9s de Valdecilla University Hospital) Juan
- C Roslani April
- C Tucker Sarah
- C Velmahos (Massachusetts General Hospital) George
- C Winter Stuart
- Caballero Albert
- Cairo University) Mahmoud MA Elfiky (Kasr Alainy Faculty of Medicine
- Calcerrada-Alises Enrique
- Camacho Fern\ue1ndez-Pacheco (Complejo Hospitalario Universitario Insular-Materno Infantil) Borja
- Camarero Enrique
- Campagnaro Tommaso
- Campanelli Michela
- Candiani Massimo
- Cannoletta (Royal Brompton Hospital) Marina
- Cantalejo-Diaz (Hospital Universitario Miguel Servet) Miguel
- Cao Han
- Capizzi Vita
- Carcano (Ospedale di Circolo Giulio
- Carissimi Francesca
- Carlini Massimo
- Carlos Bernal-Sprekelsen Juan
- Carlos Catal\ue1 Bauset (Consorcio Hospital General Universitario) Juan
- Carlucci Michele
- Carmela Giuffrida Maria
- Carmichael Heather
- Carrasco Milagros
- Carrillo Mariana
- Carvello Michele
- Casati Massimiliano
- Castoro Carlo
- Castro Ruiz Carolina
- Catalan Vanesa
- Catriona R Luney (Nuffield Orthopaedic Centre) Benjamin JF Dean
- Cavaleiro Salom\ue9
- Cellerino Paola
- Center Amsterdam) Cancer
- Centinaio (Ospedale Maggiore di Lodi) Giovanna
- Cernei Cristina
- Cervellera Maurizio
- Chakrabortee Sohini
- Chamberlain Stephanie
- Chan Jeffrey
- Chang Grace
- Chaudhry Daoud
- Chebaro Alexandre
- Chen (Jamaica Hospital) David
- Chetty Govind
- Chia (Royal Derby Hospital) Zoe
- Chiappini Ambra
- Chiarugi (Azienda Ospedaliero Universitaria Pisana) Massimo
- Chidambaram Swathikan
- Chiozza Matteo
- Cholewa Hanna
- Chong (Evelina London Children's Hospital) Clara
- Choolani-Bhojwani Ekta
- Christian Cotsoglou (ASST Vimercate) Stefano Granieri
- Chui Karen
- Chung Choyin
- Cirillo Bruno
- Citterio Davide
- Clermidi Pauline
- Coccolini Federico
- Colletti Gaia
- Compagnoni Bruno
- Concepci\uf3n-Mart\uedn Vanesa
- Confalonieri Marco
- Connolly Hannah
- Conso Christel
- Conti Luigi
- Cooper Zara
- Corral Javier
- Costa Marta
- Costanzi Andrea
- Cox Daniel
- Cozza Valerio
- CR Wormald Justin
- Croatia: Jakov Mihanovic Nicolas Duchateau (Heilig Hart Ziekenhuis Lier).
- CS Clough Ethan
- Cuming Tamzin
- Cuneo)
- Curtis Miles
- Cuschieri Joseph
- D Baron Ryan
- D Bosch Karen
- D Brown Oliver
- D Bueno-Ca\uf1ones Alejandro
- D Cato Liam
- D Drake Thomas
- D Jenkinson Michael
- D Jenkinson Michael
- D Liyanage Aloka S
- D Pinkney Thomas
- D Rajgor Amarkumar
- D Stewart Grant
- D Tebala Giovanni
- D'Agruma Michele
- D'Andrea Giancarlo
- D\uedaz P\ue9rez David
- D\uedaz-Garc\ueda (Hospital Universitario Nuestra Se\uf1ora de Candelaria) Alberto
- Da Roit Anna
- da Saliceto\u201d Patrizio Capelli (Ospedale \u201cG.
- Dare Oliver
- Darko Ebenezer
- Data Monitoring and Ethics Committee: Deborah S Keller H. Hunt Batjer (University of Texas Southwestern).
- Day Andrew
- De Andr\ue9s-Asenjo Beatriz
- de Medicina Facultad
- De Miguel-Ardevines Maria-Carmen
- De Nardi Paola
- De Simone Veronica
- De Toma Giorgio
- Deepti Sinha (University College London Hospital) Nicholas Kalavrezos
- Dehal (Kaiser Permanente Panorama City Medical Center) Ahmed
- Dehart Dustin
- Del Giudice Roberto
- Delgado-Oliver Eduardo
- Denmark: Henry G Smith Bernarda Bakmaz (Zadar General Hospital).
- Denning Max
- Desai Anant
- Desender (Ghent University Hospital) Liesbeth
- Dester (ASST Valcamonica Ospedale di Esine) Sara
- Di Candido Francesca
- Di Chiara Francesco
- Di Franco Gregorio
- Di Giuseppe (Ente Ospedaliero Cantonale del Canton Ticino) Matteo
- Di Saverio Salomone
- Di Saverio Salomone
- Di Saverio Salomone
- Di Saverio Salomone
- Diaz-Pe\uf1a Patricia
- Dieguez Fernandez Beatriz
- Dissemination Committee: Michel Adamina Aneel Bhangu.
- Dolores Del Toro M
- Domodossola
- Doussot Alexandre
- Duff Sarah
- Dunning Joel
- Dunstan Matt
- Duque-Mallen Victoria
- Dziakova Jana
- E Canova Michaela
- e Carle Hospital Chiara Peluso (Santa Croce
- e Carlo ASST Santi Paolo
- E Dawson Brett
- E Dickson Kathryn
- E Hudson Victoria
- E Jenny (Johns Hopkins Hospital) Hillary
- E Lewis Sophia
- E Nita George
- e Oftalmico) Giulio Iacob (Ospedale Fatebenefratelli
- E P\ue9rez-S\ue1nchez Luis
- E Rice Henry
- E Ssentongo Anna
- e Universit\ue1rio de Coimbra) Ana C Almeida (Centro Hospitalar
- E Xyda Souzana
- Edward Fitzgerald J
- EF Abbott Tom
- EF Abbott Tom
- Egan Richard
- Egypt: Mohamed El Kassas University of Copenhagen).
- El Youzouri Hanan
- El-Ali (Queen's Hospital Abess
- Elaine YL Leung (The Pan Birmingham Gynaecological Cancer Centre) Sudha Sundar
- Elfeki Hossam
- Elhadi Muhammed
- Eljareh (Aljalaa Hospital) Mohammed
- Elkadi Hannah
- Elkady Ramy
- Elkhafeefi Fatimah
- Elmore Ugo
- Elmoslemany (The Walton Centre NHS Foundation Trust) Tarek
- EM Bouhuwaish Ahmad
- EM Brathwaite Collin
- Emmerson (North Manchester General Hospital) Oliver
- Enemosah Ibrahim
- English Camilla
- English William
- Ereidge Simon
- Escartin Jorge
- Estaire-Gomez Mercedes
- EuroSurg
- Evans (Queen Elizabeth the Queen Mother Hospital Margate) Jessica
- Exley Rebecca
- F Bath Michael
- F Cunha Miguel
- F Cunha Miguel
- F Davis Niall
- F Ridgway Paul
- Fabbri Nicol\uf3
- Falco Giuseppe
- Familiari Pietro
- Fancellu (Cliniche San Pietro Alessandro
- Fanjul G\uf3mez Mar\ueda
- Farik Shebani
- Farr\ue9 Font Roser
- Farrell Tony
- Fehervari Matyas
- Fell Adam
- Fern\ue1ndez- Mart\uednez Mar\ueda
- Fern\ue1ndez-Gomez Cruzado (Hospital Urduliz) Laura
- Fern\ue1ndez-Mar\uedn Reyes
- Fernandez-Camu\uf1as Angel
- Ferrara)
- Ferrara Francesco
- Ferrari Guglielmo
- Ferrero Simone
- FF Simoes Joana
- FF Simoes Joana
- Findlay Laura
- Fiore Marco
- Fiore Marco
- Fiori Enrico
- FJ Dunne Declan
- Flatman Michael
- Flindall Ian
- Fontana (Vittorio Emanuele Tommaso
- Ford (The Robert Jones and Agnes Hunt Orthopaedic Hospital) David
- Ford Samuel
- Forlani Stefano
- Fr\ue9d\ue9ric Bretagnol (H\uf4pital Louis-Mourier - GHU AP-HP. Nord - Universit\ue9 de Paris) David Moszkowicz
- France: Zaher Lakkis Mohamed Sherief (MISR Cancer Center/MISR International Hospital).
- Francisco de Vitoria Universidad
- Francone Elisa
- Frattaruolo Colomba
- Frio (Institute of Neurological Sciences of Bologna Federico
- Frosinone)
- G Aoun Salah
- G Barranquero Alberto
- G Blazer III Dan
- G Collins Chris
- G Edwards John
- G Edwards John
- G Morton Dion
- G Povey Meical
- G Velopulos Catherine
- G Wade Ryckie
- Gabriel Kinnaman (IU Health Methodist Hospital) Ashley D Meagher
- Gagliano Annalisa
- Gagliardi Filippo
- Gahunia Sukhpreet
- Gala Tanzeela
- Galfrascoli Elisa
- Galimberti Luca
- Galindo Jara (Hospital Universitario de Torrej\uf3n Pablo
- Gallagher Phoebe
- Galleano Raffaele
- Gallo Gaetano
- Gallo Gaetano
- Gallo Gaetano
- Galv\ue1n-P\ue9rez Armando
- Gamal Amira Ibrahim Sallam
- Gammeri Emanuele
- Ganau Mario
- Garc\ue9s-Garc\ueda Ra\ufal
- Garcia Fernandez Andres
- Garcia-Conde Delgado Maria
- Garulli (Ospedale Infermi di Rimini) Gianluca
- Gascon-Ferrer Isabel
- Gattolin (Regina Montis Regalis Hospital Andrea
- Gaujoux Sebastien
- Gentilli Sergio
- Georgiades Fanourios
- Germany: Carsten Kamphues Didier Ollat (Institut Mutualiste Montsouris).
- Gerogiannis (Kingston Hospital NHS Foundation Trust) Ioannis
- Ghanbari (Homerton University Hospital) Amir
- Ghosh Dhruv
- Giacometti Marco
- Giblin Anna-Victoria
- Gilbert (Surrey and Sussex Healthcare NHS Trust) Catherine
- Gim\ue9nez Clara
- Giorgakis Emmanouil
- Gipponi Manuel
- Glen Paul
- GlobalPaedSurg GlobalSurg
- Goatly Giles
- Gobatti (San Carlo Borromeo Hospital Davide
- Godbole Chintamani
- Gohil Kajal
- Gomez-Rosado Juan-Carlos
- Gonullu Emre
- Gonzalez-De Miguel Melania
- Gonzalez-Gonzalez Enrique
- Gordini Luca
- Gracia Isabel
- Gracia-Roche Carlos
- Greece: Konstantinos Bouchagier Markus W L\uf6ffler (University Hospital Tu\u308bingen).
- Green Susanna
- Grivon Manuela
- Grove (Department of Colorectal Surgery Thomas
- Guaglio Marcello
- Guaitoli (Perrino) Eleonora
- Guglielmi Alfredo
- Guha Soumya
- Gustavino (Unit of Obstetrics and Gynecology IRCCS Ospedale Policlinico San Martino Genoa) Claudio
- Guti\ue9rrez Samaniego Mar\ueda
- H Babu Bheemanakone
- H Chowdhury Abeed
- H Davidson Giana
- H Davidson Giana
- H Davidson Giana
- H Elfallal Ahmed
- H Emile Sameh
- H Kirmani Bilal
- H Liu Helen
- H Murphy Suzanne
- H van Ramshorst Gabrielle
- H\uf6lzle Frank
- Habeeb Amir
- Hagger Robert
- Hakmi Hazim
- Halkias Constantine
- Halkias Constantine
- Hampton (Rotherham District General Hospital) Matthew
- Handa Siddhartha
- Haq Iram
- Harky (Liverpool Heart and Chest Hospital) Amer
- Harries (Morriston Hospital Rhiannon
- Harrison Joseph
- Hasan Raashad
- Hawari Mohammad
- Hawkin Paul
- Hebblethwaite Bethany
- Helier University Hospitals NHS Trust) St
- Heritage Emily
- Hernandez Garcia Miguel
- Hernandez-Juara Pilar
- Herrero-Lopez Maria
- Hervieux Erik
- Heyd Bruno
- Higgs Simon
- Hitchman (Hull University Teaching Hospitals NHS Trust) Louise
- Ho Beatrice
- Hogan Aisling
- Hospital of Varese University
- Hospital Universitario del Henares) Miguel Angel Garcia-Ure\uf1a (Universidad Francisco de Vitoria
- Hospital) Atakent
- Hospital) Wythenshawe
- Hossain Tanvir
- Houston Roy
- Hurt Libor
- HV Byrne Matthew
- i Pujol) Alba Zarate (Hospital Germans Trias
- I Roxo (Brigham and Women's Hospital) Vanessa
- I van Berge Henegouwen (Amsterdam UMC Mark
- I Alessandro Di Bartolomeo (Policlinico Umberto
- Iannone Immacolata
- Ibrahim Sherif
- Iovino Domenico
- Ireland: Arnold DK Hill Paraskevi Tourountzi (Kavala General Hospital).
- Isik Arda
- Israel: Oded Zmora Thomas M Aherne (Galway University Hospital).
- Italy: Maurizio Zizzo Nadav Kugler (Shamir Medical Center).
- J Abbott Sarah
- J Baker Olivia
- J Baldwin Alexander
- J Beamish Andrew
- J Carlos William
- J Caruana Edward
- J Caruana Edward
- J Davies Emma
- J Diaz Jose
- J Doe Matthew
- J Eardley Nicola
- J Fern\ue1ndez Antonio
- J G\uf3mez D\uedaz Carlos
- J Hainsworth Alison
- J Hall Bria
- J Holme Thomas
- J Hutchinson Peter
- J Hutchinson Peter
- J Kalkwarf Kyle
- J Lin Daniel
- J Lowery Aoife
- J McCluney Simon
- J Mehigan Brian
- J Mills Sarah
- J Pachl (Birmingham Children's Hospital) Max
- J Rogers Luke
- J Ryan \uc9anna
- J Scurrah Rachel
- J Shackcloth Michael
- J Smart Neil
- J Steinkamp Pieter
- J Tejero-Pintor Francisco
- J Thomas Amy
- J Torres Antonio
- J Warren Oliver
- J Warren Oliver
- J Williams Katherine
- James RW Hall (Stepping Hill Hospital) Claire Hall
- James's Hospital) Conor P Barry (St.
- Jamil Tahir
- Jayaraju (University Hospital of Wales) Ullas
- Jenner Edward
- JG Chase Thomas
- Jha Shane Lester (James Cook University Hospital) Madan
- Jimenez-Higuera Elisa
- Jimeno Jaime
- JM Dunne Naomi
- JM Ferguson Henry
- Jo\ue3o Lima Maria
- Johnstone Jack
- Jones Mark
- Jordan: Mahmoud Al-Masri Gela).
- JS Wall Joshua
- Judkins Nicholas
- JW Wilkin Richard
- K Abou Chaar Mohamad
- K Ambler Graeme
- K Bankhead-Kendall Brittany
- K Bankhead-Kendall Brittany
- K Bankhead-Kendall Brittany
- K Brown Allison
- K Fusai Giuseppe
- K Gill Charn
- K Kamarajah Sivesh
- K Patel Panna
- K Ubhi Harmony
- K Weerasinghe Chamindri
- K\uf6nigsrainer Alfred
- Kalidindi Venugopala
- Kamal Mona
- Kang Chong
- Kara Yasin
- Karam Edward
- Karim Ahmed
- Kashora Florence
- KC Jonker (University Medical Center Groningen (University of Groningen) Pascal
- Kearney (Beaumont Hospital) David
- Khajuria Apoorva
- Khan Azam
- Khan Umul
- Khatri Chetan
- Kinross James
- Kler Aaron
- Klimopoulos (Evangelismos General Hospital) Serafeim
- Kocata\u15f (Kanuni Sultan Suleyman Training and Research Hospital) Ali
- Kolias Angelos
- Kolias Angelos
- Kontovounisios Christos
- Kourdouli (Leicester Royal Infirmary) Amar
- Krishnan Emily
- Kristinsson Sverrir
- Kruijff Schelto
- KS Viswanath Yirupaiahgari
- Kudsk-Iversen S\uf8ren
- Kufeji Dorothy
- Kulkarni Rugved
- Kurihara Hayato
- L Biffl Walter
- L Coleman Natasha
- L Collins Michelle
- L Engel (Temple University Hospital) Jamie
- L Fowler Amy
- L Garcia Galocha Jose
- L Hughes Jane
- L J\uf6nsson (Bispebjerg Hospital Maria
- L Labib Peter
- L Marsh (Scripps Memorial Hospital) Christopher
- L McKevitt Kevin
- L Osorio Alexander
- L Romera Jose
- L Serevina Olivia
- L Venn Mary
- L Venn Mary
- L Venn Mary
- L Wright Franklin
- L Young Alastair
- L\ue1zaro Andr\ue9
- La Torre Filippo
- Laface (Ospedale Vittorio Emanuele III Letizia
- Lami Mariam
- Landaluce-Olavarria Aitor
- Laura Hansen 9
- Lawani Ismail
- Lawday (Southmead Hospital) Samuel
- Lawday Samuel
- Le Roy Bertrand
- Lecco) Asst
- Lecolle Katia
- Lederhuber Hans
- Lederhuber Hans
- Leeds)
- Leicester)
- Leventoglu Sezai
- Li Elizabeth
- Li Elizabeth
- Li Zoe
- Libya: Ghadah Z Alkadeeki Hani Al-Najjar (King Hussein Cancer Center).
- Liew Ignatius
- Ligure (SV) Pietra
- Lima Buarque Igor
- Lisi Giorgio
- Lizzi Vincenzo
- Lo Terence
- Lombardia) Regione
- Lomiento Daniele
- Longhi Marco
- Lopez Antonanzas (Hospital Clinico San Carlos Leyre
- Losada Ruiz Manuel
- Lostis Emilie
- Lostoridis Eftychios
- Loubani Mahmoud
- Lowy- Benoliel Alejandro
- Lucianetti (Papa Giovanni XXIII Hospital) Alessandro
- Luigi MP Marino Cosentino (PO San Filippo Neri - ASL ROMA 1) Andrea Sagnotta
- luis Blas Laina Juan
- Luke Evans (Norfolk and Norwich University Hospital) Mina MG Youssef
- Luke Louis
- Lunevicius Raimundas
- Luraghi Marco
- Lye George
- M Alrahawy (Menofiya University Hospital) Mahmoud
- M Andreani Stefano
- M Ashoush Fouad
- M Bajomo Oreoluwa
- M Blundell Chris
- M Cicerchia Pierfranco
- M Connolly Tara
- M Diez-Alonso Manuel
- M Dur\ue1n-Mu\uf1oz-Cruzado (Hospital Universitario Virgen del Rocio) Virginia
- M Emslie Katy
- M Harrison Ewen
- M Holbrook Charlotte
- M Isolani Simone
- M Keatley James
- M Leite-Moreira Andr\ue9
- M Mithany Reda H
- M Mohan Helen
- M Mohan Helen
- M Monteiro Joana
- M Morgom (Tripoli Central Hospital) Marwa
- M Muguerza Jose
- M Nunes Quentin
- M Nygaard Rachel
- M Omar Aneel Bhangu Omar
- M Philp Matthew
- M Pollok Joerg
- M Rooney Siobhan
- M Sampietro Gianluca
- M Sewards Joseph
- M Tang Alethea
- M Trout Isobel
- M Walters (Harborview Medical Center Andrew
- MA Kaafarani Haytham
- MA Kaafarani Haytham
- MA Kaafarani Haytham
- Maarten van Heinsbergen (VieCuri Medisch Centrum) Joop Konsten
- Mabrouk Islam
- Macchi Alberto
- MacDonald Luisa
- Machairas (Royal Free Hospital) Nikolaos
- Madonini Marco
- Madrid)
- Madrid)
- Magalh\ue3es Maia Mariana
- Magne Augestad Knut
- Magowan Drew
- Maha H Haqqani (Boston Medical Center) Frederick T Drake
- Maisonneuve Emeline
- Majkowska Agata
- Majkowski (Northern General Hospital Lawrence
- Mak (Queen Elizabeth Hospital Birmingham) Jason
- Malabarba Stefano
- Malerba Michele
- Maninder Kalkat 7
- Mannan Syed
- Manson Joanna
- Mansuri Ahmer
- Mantoglu (Sakarya University Research and Educational Hospital) Baris
- Manu Nichola
- Manzoni 56 Via
- Maqsood Afnan
- Marano Alessandra
- Marchbank Adrian
- Marcos-Santos Pablo
- Marinos Kouris (Buckinghamshire Healthcare NHS Trust) Spyros
- Marqueta De Salas Maria
- Marrano Enrico
- Mart\uedn-Rom\ue1n Lorena
- Mart\uednez P\ue9rez Carolina
- Mart\uednez-dePaz Fernando
- Martel Lozano Saida
- Martin (St Mary's Hospital) Guy
- Martin Emmeline
- Martin Janet
- Martin-Albo Lorena
- Martine Uittenbogaart (M\ue1xima Medical Center) Wouter KG Leclercq
- Martinelli Fabio
- Martinez-German Antonio
- Martinez-Pinedo Carlos
- Martins Ricardo
- Marwan Hisham
- Marzi Federica
- MAS Baig Mirza
- Mateos-Sierra (Hospital General Universitario Gregorio Mara\uf1\uf3n) Olga
- Mater Studiorum University of Bologna) Alma
- Mathieu (CHU Besan\ue7on) Pierre
- Matute-Najarro Maria-Soledad
- Maw Andrew
- Mazingi Dennis
- Mazzaferro (Fondazione IRCCS Istituto Nazionale dei Tumori Vincenzo
- McCanny (Antrim Area Hospital) Andrew
- McKenzie Katherine
- McLarty (Northumbria NHS Hospital Trust) Nicola
- McPherson Iain
- Medina Esther
- Mediratta Saniya
- Medone Marzia
- Mehra (Guy's and St Thomas\u2019 NHS Foundation Trust) Gautam
- Mele Simone
- Melero-Cort\ue9s Lidia
- Melody Baeza (Morales Meseguer University Hospital) Jos\ue9 Aguilar
- Mendon\ue7a Ata\uedde Gomes Gustavo
- Mendoza-Moreno Fernando
- Meneghini Simona
- Merate
- Mercante Giuseppe
- Merdrignac (Rennes University Hospital) Aude
- Metallidis Symeon
- Michel (Pinderfields Hospital) Martin
- Migliore Marco
- Milan)
- Milan)
- Milan)
- Miller Douglas
- Minaya- Bravo Ana
- Minaya-Bravo Ana
- Minaya-Bravo Ana
- Minaya-Bravo Ana
- Mingoli Andrea
- Minto Gary
- Mirabella Antonello
- Misra Nikhil
- Mitrasinovic Stefan
- Miu Victor
- Moawad (Royal Victoria Hospital) Nader
- Mochet Sylvie
- Modabber Ali
- Mohammad Adam
- Mohan Midhun
- Moliner-S\ue1nchez Carmen
- Mondov\uec)
- Mongelli Francesco
- Monteleone (Ospedale San Leopoldo Mandic Michela
- Montuori Mauro
- Moore Rachel
- Mora-Guzm\ue1n (Hospital Santa B\ue1rbara) Ismael
- Morales Dieter
- Morales Xavier
- Morelli Luca
- Morelli Lucia
- Morgan Richard
- Morris Chris
- Mortini Pietro
- Mosca Angelo
- Moszkowicz David
- Moszkowicz David
- Motter Dema
- Moug Susan
- Mukherjee Samrat
- Munoz Rivas Ana
- Murcia)
- N Bence Matthew
- N Hopkinson David
- N Mashbari Hassan
- N Mashbari Hassan
- N Mashbari Hassan
- N Naumann David
- N Rao Jagan
- N Townshend David
- N\ufa\uf1ez Jordi
- Najdy Manhal
- Nakas (Glenfield Hospital Apostolos
- Namazov Ilgar
- Naredla Pradyumna
- Nasef Emmhamed
- Nassa Heeam
- Nath Rahul
- Navarro-S\ue1nchez Antonio
- Nazarian (Bupa Cromwell Hospital) Scarlet
- Neal Bhutiani (University of Louisville Hospital and Norton Hospital) Robert CG Martin
- Negri Giampiero
- Nehra Deepika
- Neil-Dwyer Jason
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Nepogodiev Dmitri
- Neri Jacopo
- Netherlands: Suzanne S Gisbertz Mustafa R Bulugma (Zawia Teaching Hospital). Mexico: Fernando Cordera (ABC Medical Center).
- Newton (Manchester Royal Infirmary) Katy
- Nikaj (Azienda Ospedaliero Universitaria Maggiore della Carit\ue0 Herald
- Niquen Milagros
- Nobile (Azienda Ospedaliera Universitaria Integrata di Verona) Sara
- Nogueiro Jorge
- Nogues Pevidal (Royo Villanova) Ana
- Novara)
- Ntirenganya Faustin
- Nugent Michael
- O Ademuyiwa Adesoji
- O Kavanagh Dara
- O Larkin John
- Oca\uf1a Juan
- of Amsterdam University
- of Ferrara) University
- of Insubria University
- of Milan) University
- of Surgeons in Training (ASiT) Association
- of Surgery) Department
- of Washington) University
- Okafor Barbara U.
- Okechukwu Valentine
- Oliva-Mompean (Hospital Universitario Virgen Macarena) Fernando
- Oliveira Ana
- OM Abdalla Mutwakil
- Omar M Omar
- OO Ayorinde John
- Osagie-Clouard (Epsom &
- Osman (Walsall Manor Hospital) Khabab
- Ottolina Jessica
- Ourieff (Mount Sinai Hospital) Jared
- Outani Oumaima
- Oyewole Bankole
- P Arnaud Alexis
- P Arnaud Alexis
- P Arnaud Alexis
- P Baker Markus
- P Belgaumkar Ajay
- P Boddy Alexander
- P Duffy (Nottingham City Hospital) John
- P Evans Jonathan
- P Hazelton Joshua
- P Jones Andrew
- P Jones Robert
- P Joyce Doireann
- P Kisiel Aaron
- P Pezzuto Anna
- P Singh Rabindra
- P\ue9rez-Gonz\ue1lez Marta
- P\ue9rez-Saborido Baltasar
- Pacheco-Sanchez David
- Padilla-Valverde (Hospital General Universitario De Ciudad Real) David
- Pai (Hammersmith Hospital) Madhava
- Paiella Salvatore
- Paisley (Brighton and Sussex NHS Trust Samuel
- Palermo)
- Palini Gianmarco
- Palmeri Matteo
- Parente Alessandro
- Parlanti Daniele
- Parmar Chetan
- Pascual Angela
- Pata Francesco
- Pata Francesco
- Patel Mahul
- Pathak Abhijit
- Patil Sangram
- Pattyn Piet
- Peckham- Cooper Adam
- Pedram Panahi (University Hospitals Plymouth NHS Trust) Mariam Rela
- Pedrazzani Corrado
- Pellino Gianluca
- Pereira Andr\ue9
- Pereira-Neves Ant\uf3nio
- Perez-Diaz Md
- Perivoliotis (General University Hospital of Larissa) Konstantinos
- Perkins Clare
- Perotto (CHU Saint Etienne) Ornella
- Perra Teresa
- Petrone Patrizio
- Phenix George
- Piacenza)
- Picazo Sara
- Picon-Rodriguez Rafael
- Piloni Martina
- Pingarr\uf3n-Mart\uedn Lorena
- Pinotti Enrico
- Pizzini Paolo
- PM de Vries Jean-Paul
- Pockney Peter
- Podolsky Dina
- Poggioli Gilberto
- Pompili Cecilia
- Pontari Michael
- Porcu Alberto
- Portugal: Hugo Santos-Sousa Pakistan: Mariyah Anwer (Jinnah postgraduate medical center).
- Potter (Royal Bournemouth Hospital) Ryan
- Price Claire
- Prita Daliya 8
- Pruvot (Lille University Hospital) Fran\ue7ois-Ren\ue9
- PTSurg ItSURG
- Pujol-Muncunill Roger
- Puppo Andrea
- Q Mehdi (University of Texas Medical Branch) Mohammad
- Quante Markus
- Quintana-Villamandos Bego\uf1a
- Qureshi Ali
- R Burke Joshua
- R Davidson Brian
- R Dixon Jan
- R Fretwell Kenneth
- R Gujjuri Rohan
- R Gujjuri Rohan
- R Kowal Mikolaj
- R O\u2019Neill John
- R Sarma Diwakar
- R Spalding Duncan
- R Springford Laurie
- Rachel Baumber (Royal National Orthopaedic Hospital) James T Parry
- Radenkovic Dejan
- Rahman Saad (Medway Maritime Hospital) Abdel
- Rakvin Ivan
- Ramallo-Sol\ueds Irene
- Ramcharan Sean
- Ramos Diego
- Ramos-Bonilla Antonio
- Ramos-De la Medina Antonio
- Ramzi Joussi
- Rathinam Sridhar
- Rausa Emanuele
- Ravaioli Matteo
- Ravindran Sharanya
- Raymond (Royal Lancaster Infirmary) Thomas
- Razik Aisha
- Redfern (Furness General Hospital) Jennifer
- Reguera-Rosal Julio
- Rey-Biel Juan
- Rey-Valcarcel Cristina
- RG Sheel Andrea
- Ribolla Marta
- Richards Tomos
- Richmond (University of Maryland Medical Center) Michael
- Righini (Ospedale del Delta Erminio
- Rio-Gomez Javier
- Riuniti Villa Sofia-Cervello Ospedali
- Riyat Harjoat
- Rizvi Sana
- Roberts Keith
- Roberts Matthew
- Robertson (University Hospitals Coventry and Warwickshire) Stuart
- Robertson (University of Arkansas for Medical Sciences) Ronald
- Robin-Valle Alvaro
- Rochon Melissa
- Rojo Mikel
- Rolli Luigi
- Romano Silvio
- Rome)
- Romford)
- Ross Elizabeth
- Ross Howard
- Rottoli Matteo
- Royal Hospital) Princess
- Ruiz (Hospital General Universitario Reina Sof\ueda Miguel
- Ruiz- Grande Fernando
- Ruiz-Martin (Rey Juan Carlos University Hospital) Irene
- Ruiz-Soriano (Hospital Cl\uednico Universitario de Valladolid) Mar\ueda
- Ruzzenente Andrea
- Ryska Ondrej
- S Abdelaal (Alexandria Main University Hospital) Ahmed
- S Al Maadany Faraj
- S Faria Carlos
- S Hammond John
- S Hossain Fahad
- S Jeyaretna Deva
- S Jones Conor
- S Khan (Queen Alexandra Hospital) Jim
- S Moura Francisco
- S Ng-Kamstra Joshua
- S Sica Giuseppe
- S Tamimy Muhammad
- S Wadley Martin
- S\ue1nchez- Arteaga Alejandro
- SA Taher Ahmed
- Saez Carlos
- Sahnan Kapil
- Sahni Arun
- Salim Ali
- Salvia Roberto
- Sammarco Giuseppe
- Sampaio-Alves Mafalda
- San Miguel-Mendez Carlos
- Sanchez del Pueblo Cristina
- Sanchez-Fuentes Maria-Nieves
- Sanchez-Pelaez Daniel
- Sanchez-Perez Coral
- Sanchez-Rubio Maria
- Sancho-Muriel Jorge
- Sanchon Fructuoso Lorena
- Sanders Julie
- Santero-Ramirez Maria-Pilar
- Santora Thomas
- Santoro Antonio
- Santos Irene
- Sapienza Paolo
- Sartarelli (Sant\u2019Orsola Hospital Lodovico
- Sarveswaran Janahan
- Sasia Diego
- Sassari) A. O. U.
- Saudemont Alain
- Saudi-Moro Sef
- Saxena Dolly
- Saxena Shobhit
- Sayasneh Ahmad
- Scalabre Aurelien
- Schache Andrew
- Schiavina Riccardo
- Schineis (Charit\ue9 University Medicine Christian
- Schreckenbach Teresa
- Scorza Antonella
- Scott Lucy
- Seegert (ProMedica Toledo Hospital) Sara
- Seguin-Givelet Agathe
- Senent-Boza Ana
- Serrano Gonz\ue1lez Javier
- Sette Laghi Asst
- Seymour Keith
- Shabana Amanda
- Shah (The Whittington Hospital) Sujay
- Shah Jigar
- Shah Karishma
- Shah Preena
- Shakir Taner
- Shalaby (Mansoura University Hospital) Mostafa
- Shankar (Oxford University Hospitals NHS Foundation Trust Sushma
- Shaw Richard
- Sheffield)
- Shehata Sameh
- Shelley Hwang E.
- Shen Ban Vin
- Shenfine Amy
- Sheridan Kelda
- Sherief Ahmed
- Sherif Mohamed
- Shinkwin Michael
- Shu Sebastian
- Siaw-Acheampong Kwabena
- Sileri (San Raffaele Scientific Institute Pierpaolo
- Singh Abhinav
- Singh Shailendra
- Sinha Sanjay
- Siragusa (Policlinico Tor Vergata Hospital Leandro
- Sivaprakasam Rajesh
- Sivayoganathan Sriharan
- SJ Ledesma Frances
- Smillie Robert
- Smith (Countess of Chester Hospital) Claire
- Smith Andrew
- Smith Christopher
- Sochorova (Royal Liverpool University Hospital) Dana
- Society of Coloproctology (ESCP) European
- Society of Colorectal Surgery (SICCR) Italian
- Soggiu Fiammetta
- Sohrabi (St Bartholomew's Hospital) Catrin
- Sohrabi (Whipps Cross University Hospital) Catrin
- Sohrabi Catrin
- Solari (Royal Gwent Hospital) Francesca
- Solli Piergiorgio
- Soreide Kjetil
- Soto Montesinos Cristina
- SpainSurg
- Spinelli Antonino
- Spinelli Antonino
- Spoletini (Sant'Eugenio Hospital) Domenico
- Spriano Giuseppe
- Sravanam Sanskrithi
- Ssentongo (Pennsylvania State University) Paddy
- Stanger Sophie
- Stavroulias Dionisios
- Steel (Sunderland Royal Hospital) Ben
- Stella Marco
- Stewart Robbie
- Stringer Sally
- Sudan: Osman M Ali Elima P Cagigal- Ortega (Hospital Universitario Severo Ochoa).
- Sulen Nina
- Sundar Sudha
- Sundhu (Aintree University Hospital) Matthew
- Surgical Research Collaborative (ISRC) Irish
- Suri (University of California Davis Health Avni
- Swansea)
- Switzerland: Dimitri Christoforidis Ali A Ali karar (Al-rajhi).
- Syed Arooj
- Szatmary Peter
- T Colonna Emily
- T Enjuto Diego
- T Montella (Azienda Unit\ue0 Sanitaria Locale-IRCCS di Reggio Emilia) Maria
- TA Neely David
- Tabiri Stephen
- Tadross Daniel
- Taglietti Lucio
- Tansey (Princess Alexandra Hospital) Rosamond
- Tartaglia Dario
- Tawheed (Endemic Medicine Department Ahmed
- Tayeh Salim
- Testa Valentina
- Tewari Nilanjana
- Thoenissen Philipp
- Thomas (Worcestershire Acute Hospitals NHS Trust) Kane
- Thrush Jessica
- Tierney Sean
- Tiwari Abhinav
- Tobias Teles (Hospital de Cascais - Dr. Jos\ue9 de Almeida) Pedro A Serralheiro
- Toledo Enrique
- Tonini Valeria
- Torkington Jared
- Torzilli Guido
- Totty Joshua
- Tousidonis Manuel
- Townend Philip
- Townsend Catherine
- Trompeter (St George's Hospital) Alex
- Trotta Francesco
- Truant St\ue9phanie
- Trujillo-D\uedaz Jeancarlos
- Tsoulfas George
- Tsoulfas Georgios
- Turco Celia
- Turkey: Volkan Ozben Georgios Peros (Kantonsspital Winterthur).
- Turrado- Rodriguez Victor
- Turri Giulia
- Tustin (Cumberland Infirmary) Harry
- Tyler Jayne
- Tzedakis Stylianos
- Tzovaras George
- Ullah Ramzan
- Unit\ue0 Sanitaria Locale di Ferrara Azienda
- United Kingdom: Richard J Davies Alp Yildiz (Yildirim Beyazit University Yenimahalle Training and Research Hospital).
- United States: John RT Monson (AdventHealth Orlando) Lavinia Onos (York Teaching Hospitals NHS Trust).
- University Hospitals NHS Trust) Nottingham
- University of Rome) Sapienza
- University) Goethe
- University) Helwan
- Urban (University of Colorado Hospital) Shane
- Urbani (Azienda Ospedaliero Universitaria San'Anna Alessia
- Usai Antonella
- V Bhavaraju Avi
- V Comini Lara
- V Feo Carlo
- V Marino Marco
- V Shaw Abigail
- V\ue1zquez- Fern\ue1ndez Andrea
- Vaccarella (Azienda Ospedaliera Gianpaolo
- Valdes- Hernandez Javier
- Valsecchi Luca
- Vashisht Rajiv
- VCO) Asl
- Venkatesan (Glan Clwyd Hospital) Gowtham
- Vera-Mansilla Cristina
- Vergari (Ospedali Riuniti di Ancona) Roberto
- Vescio (University 'Magna Graecia' of Catanzaro) Giuseppina
- Vidya Raghavan
- Vieira (Centro Hospital Universit\ue1rio S\ue3oJo\ue3o) Paula
- Vijay Vardhini
- Vimalachandran Dale
- Vimalachandran Dale
- Violante Tommaso
- Vovola Fernanda
- Vulliamy Paul
- W Endorf (Hennepin Healthcare) Frederick
- W Etchill Eric
- W L\uf6ffler Markus
- W L\uf6ffler Markus
- Wall Rosemary
- Wallwork Kate
- Ward Alex
- Warwick (University Hospital Southampton) David
- Waseem Saima
- Weaver Helen
- Wells Fiona
- Wen Jiaxin
- West Raha
- Whitehall Emma
- Wild Laura
- Wilkins Alex
- Williams Gethin
- Williams Matthew
- Winnand (University Hospital Aachen) Philipp
- Wong (Addenbrooke's Hospital) Ken
- Worku (Queen\u2019s Medical Centre Dawit
- Wright Naomi
- WS Ho (Leeds Teaching Hospitals NHS Trust Michael
- WT Ngu Albert
- y Cajal) Cristina Cerro (Hospital Universitario Ram\uf3n
- Y Oo (Department of Cardiothoracic Surgery Aung
- y Polit\ue9cnico La Fe) Blas Flor (Hospital Universitario
- Y van der Plas Willemijn
- Yalamanchili Seema
- Yershov (South Warwickshire NHS Foundation Trust) Danylo
- Young Richard
- Yousra Ahmed (Portsmouth Hospital NHS Trust) Simon Toh
- Yurttas Can
- Zadegan Frederic
- Zafar (Northwick Park Hospital) Noman
- Zakaria Rasheed
- Zambon Martina
- Zanini Nicola
- ZE Durst Alexander
- Zerbib Philippe
- Zonta (Ospedale San Biagio Sandro
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research
Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
- Author
- Abel K
- Adamali H.
- Adeloye D
- Adeyemi Oluwaseun
- Adrego Rita
- Aguilar Jimenez Laura A.
- Ahmad Haider N
- Ahmad Shanaz
- Ahmed R
- Ahwireng Nyarko
- Ainsworth Mark
- Al-Sheklly B.
- Alamoudi Asma
- Alfaro-Almagro Fidel
- Ali Mariam
- Aljaroof M
- Allan L
- Allen R J
- Allerton Lisa
- Allsop Lynne
- Allt Ann Marie
- Almeida Paula
- Altmann Danny
- Alvarez Corral Maria
- Amoils S.
- Anderson David
- Antoniades C
- Arbane Gill
- Arias Ava Maria
- Armour C.
- Armstrong Lisa
- Armstrong Natalie
- Arnold David
- Arnold H
- Ashish A
- Ashworth Andrew
- Ashworth M
- Aslani S
- Assefa-Kebede Hosanna
- Atkin C
- Atkin Paul
- Aul Raminder
- Aung H
- Austin Liam
- Avram Cristina
- Ayoub A.
- Babores M.
- Baggott R
- Bagshaw J
- Baguley D
- Bailey L
- Baillie J.K.
- Bain S
- Bakali M
- Bakau M
- Baldry E
- Baldwin D
- Baldwin M
- Ballard C
- Bandula Steven
- Banerjee A
- Bang Dongchun
- Barker R E
- Barman L
- Barratt Shaney
- Barrett Fiona
- Basire Donna
- Basu N.
- Bates A
- Bates M
- Batterham R
- Baxendale H
- Bayes Hannah
- Beadsworth M.
- Beckett P
- Beggs Mark
- Begum M
- Beirne Paul
- Bell Murdina
- Bell R
- Bennett Kaytie
- Beranova Eva
- Bermperi Areti
- Berridge Anthony
- Berry C.
- Betts Sarah
- Bevan Emily
- Bhui K
- Bingham Michelle
- Birchall K
- Bishop L.
- Bisnauthsing Karen
- Blaikely J.
- Bloss Angela
- Bolger A.
- Bolton Charlotte E.
- Bonnington J.
- Botkai A
- Bourne Charlotte
- Bourne Michelle
- Bramham K.
- Brear Lucy
- Breen G
- Breeze Jonathon
- Briggs A.
- Bright E
- Brightling Christopher E
- Brill Simon
- Brindle K
- Broad Lauren
- Broadley A
- Brookes C
- Broome M
- Brown Ammani
- Brown Angela
- Brown J.
- Brown Jeremy S
- Brown Jo
- Brown M.
- Brown M.
- Brown V.
- Brugha Terry
- Brunskill Nigel
- Buch M.
- Buckley Phil
- Bularga A.
- Bullmore E
- Bunker Jenny
- Burden L.
- Burdett Tracy
- Burn D.
- Burns A.
- Burns G.
- Busby J.
- Butcher Robyn
- Butt Al-Tahoor
- Byrne S.
- Cairns P
- Calder P C
- Calvelo Ellen
- Carborn H
- Card Bethany
- Carr Caitlin
- Carr Liesel
- Carson G
- Carter Penny
- Casey A
- Cassar Mark P.
- Cavanagh J
- Chablani Manish
- Chalder Trudie
- Chalmers James D.
- Chambers R C
- Chan Flora
- Channon K M
- Chapman Kerry
- Charalambou A
- Chaudhuri N
- Checkley A
- Chen Jin
- Cheng Yutung
- Chetham Luke
- Childs C
- Chilvers Edwin R
- Chinoy H
- Chiribiri Amedeo
- Chong-James K.
- Choudhury Gourab
- Choudhury N.
- Chowienczyk P
- Christie C
- Chrystal Melanie
- Clark Cameron
- Clark D
- Clarke Jude
- Clohisey S.
- Coakley G.
- Coburn Zach
- Coetzee S.
- Cole Joby
- Coleman C
- Conneh Florence
- Connell David
- Connolly B.
- Connor Lynda
- Cook Amanda
- Cooper B
- Cooper J
- Cooper Shirley
- Copeland D.
- Cosier Tracey
- Coulding Martina
- Coupland C.
- Cox Eleanor
- Craig T.
- Crisp P
- Cristiano Daniele
- Crooks M.G.
- Cross Andy
- Cruz Isabel
- Cullinan P.
- Cuthbertson Dan J
- Daines L
- Dalton Matthhew
- Daly Patrick
- Daniels Alison
- Dark P
- Dasgin J
- David A
- David C.
- Davies Ellie
- Davies Ffyon
- Davies Gareth
- Davies Gwyneth A
- Davies Kim
- Davies Melanie J
- Dawson Joy
- Daynes E
- De Soyza Anthony
- Deakin B
- Deans Andrew
- Deas C.
- Deery Joanne
- Defres S.
- Dell Amanda
- Dempsey K.
- Denneny E
- Dennis J
- Dewar A.
- Dharmagunawardena R
- Diar Bakerly Nawar
- Dickens C
- Dipper A.
- Diver Sarah
- Diwanji Shalin N
- Dixon Myles
- Djukanovic R
- Dobson H.
- Dobson S.L.
- Docherty Annemarie B.
- Donaldson A.
- Dong T.
- Dormand N.
- Dougherty Andrew
- Dowling R
- Drain S.
- Draxlbauer K
- Drury Katie
- Dulawan Pearl
- Dunleavy A
- Dunn Sarah
- Dupont Catherine
- Earley Joanne
- Easom Nicholas
- Echevarria Carlos
- Edwards Sarah
- Edwardson C
- El-Taweel Hosni
- Elliott Anne
- Elliott K
- Ellis Y.
- Elmer Anne
- Elneima Omer
- Evans D
- Evans H
- Evans J
- Evans R
- Evans Rachael A
- Evans Ranuromanana I.
- Evans Teriann
- Evenden Cerys
- Evison Lynsey
- Fabbri L
- Fairbairn Sara
- Fairman Alexandra
- Fallon K.
- Faluyi David
- Favager Clair
- Fayzan Tamanah
- Featherstone James
- Felton T.
- Ferreira Vanessa M.
- Finch J
- Finney Selina
- Finnigan J
- Finnigan Lucy
- Fisher Helen
- Fletcher S
- Flockton Rachel
- Flynn Margaret
- Foot H
- Foote David
- Ford Amber
- Forton D
- Fraile Eva
- Francis C.
- Francis R
- Francis Susan
- Frankel A.
- Fraser Emily
- Free Rob
- French N.
- Fu X
- Fuld Jonathan
- Furniss J.
- Garner Lucie
- Gautam N
- Geddes John R.
- George J.
- George P.
- Gibbons M
- Gill Mandy
- Gill Rhyan
- Gilmour L.
- Gleeson Fergus
- Glossop Jodie
- Glover Sarah
- Goodman N
- Goodwin Camelia
- Gooptu Bibek
- Gordon Hussain
- Gorsuch T.
- Greatorex M
- Greenhaff P.L.
- Greenhalf William
- Greenhalgh Alan
- Greening Neil J
- Greenwood John P
- Gregory Heidi
- Gregory Rebecca
- Grieve D.
- Griffin Denise
- Griffiths L
- Guerdette Anne-Marie
- Guillen Guio Beatriz
- Gummadi Mahitha
- Gupta Ayushman
- Gurram Sambasivarao
- Guthrie E
- Guy Z
- Hadley K
- Haggar Ahmed
- Hainey Kera
- Hairsine Brigid
- Haldar Pranab
- Hall I
- Hall Lucy
- Halling-Brown Mark
- Hamil R.
- Hancock Alyson
- Hancock Kia
- Hanley N.A.
- Haq Sulaimaan
- Hardwick H.E.
- Hardy E
- Hardy Tim
- Hargadon Beverley
- Harrington Kate
- Harris Edward
- Harris Victoria C
- Harrison Ewen M.
- Harrison P.
- Hart Nicholas
- Harvey Alice
- Harvey M
- Harvie M
- Haslam L
- Hastie Claire
- Havinden-Williams May
- Hawkes Jenny
- Hawkings Nancy
- Haworth Jill
- Hayday A.
- Haynes Matthew
- Hazeldine J
- Hazelton Tracy
- Heaney Liam G.
- Heeley Cheryl
- Heeney J L
- Heightman M
- Heller S.
- Henderson M
- Henson Helen
- Hesselden L
- Hewitt Melanie
- Highett Victoria
- Hillman T
- Hiwot T
- Ho Ling-Pei
- Hoare Amy
- Hoare Michaela
- Hockridge J
- Hogarth Philip
- Holbourn Ailsa
- Holden S
- Holdsworth L.
- Holgate D
- Holland Maureen
- Holloway Leah
- Holmes Katie
- Holmes Megan
- Holroyd-Hind B
- Holt L
- Hormis Anil
- Horsley Alexander
- Hosseini A.
- Hotopf M
- Houchen-Wolloff Linzy
- Howard K
- Howard Luke S.
- Howell Alice
- Hufton E
- Hughes A D
- Hughes Joan
- Hughes Paul J C
- Hughes Rachel Ann
- Humphries Amy
- Huneke N
- Hurditch E
- Hurst John R
- Husain M
- Hussell T.
- Hutchinson John
- Ibrahim W
- Ilyas F
- Ingham Julie
- Ingram L
- Ionita D
- Isaacs K
- Ismail K.
- Jackson T
- Jacob Joseph
- James W.Y.
- Jang W.
- Jarman Claire
- Jarrold I.
- Jarvis Hannah
- Jastrub Roman
- Jayaraman Bhagy
- Jenkins R Gisli
- Jezzard Peter
- Jiwa Kasim
- Johnson C
- Johnson S
- Johnston D.
- Jolley Caroline J.
- Jones Don
- Jones G.
- Jones H.
- Jones Heather
- Jones I.
- Jones L.
- Jones Mark G
- Jones S.
- Jose Sherly
- Kabir T.
- Kaltsakas G.
- Kamwa V
- Kanellakis N.
- Kaprowska Sabina
- Kausar Zunaira
- Keenan Natalie
- Kelly Matthew
- Kelly S.
- Kemp Graham J
- Kerr Steven
- Kerslake Helen
- Key Angela L.
- Khan F
- Khunti Kamlesh
- Kilroy Susan
- King Bernie
- King Clara
- Kingham L
- Kirk Jill
- Kitterick P
- Klenerman P
- Knibbs Lucy
- Knight Sean
- Knighton Abigail
- Kon Onn M
- Kon S
- Kon Samantha S
- Korszun A.
- Koychev Ivan
- Kurasz Claire
- Kurupati Prathiba
- Laing C
- Lamlum Hanan
- Landers G
- Langenberg C
- Lasserson D
- Lavelle-Langham L.
- Lawrie Allan
- Lawson C
- Lawson Cathy
- Layton Alison
- Lea A
- Leavy Olivia C
- Lee D
- Lee Elvina
- Lee Ju Hee
- Leitch Karen
- Lenagh Rebecca
- Lewis D
- Lewis J.
- Lewis Keir E
- Lewis Victoria
- Lewis-Burke N.
- Li X
- Light Tessa
- Lightstone L.
- Lilaonitkul W
- Lim Lai
- Linford S.
- Lingford-Hughes A.
- Lipman M
- Liyanage Kamal
- Lloyd Arwel
- Logan S
- Lomas D
- Lone Nazir I.
- Loosley Ronda
- Lord J M
- Lota Harpreet
- Lovegrove Wayne
- Lucey Alice
- Lukaschuk Elena
- Lye Alison
- Lynch Ceri
- MacDonald S
- MacGowan G.
- Macharia Irene
- Mackie J
- Macliver L.
- Madathil S
- Madzamba Gladys
- Magee N.
- Magtoto Murphy M.
- Mairs N
- Majeed N
- Major E.
- Malein Flora
- Malim M.
- Mallison Georgia
- Man William D-C.
- Mandal S
- Mangion K.
- Manisty Charlotte
- Manley R.
- March Katherine
- Marciniak S.
- Marino Philip
- Mariveles Myril
- Marks Michael
- Marouzet E
- Marsh Sophie
- Marshall B
- Marshall M
- Martin Jane
- Martineau A.
- Martinez L.M.
- Maskell Nick
- Matila Darwin
- Matimba-Mupaya Wadzanai
- Matthews Laura
- Mbuyisa Angeline
- McAdoo S.
- McAllister-Williams H.
- McArdle A
- McArdle P
- McAulay D.
- McAuley Hamish J C
- McCann Gerry P
- McCormick Jacqueline
- McCormick W.
- McCourt P
- McCracken Celeste
- McGarvey L.
- McGee C
- Mcgee K
- McGinness Jade
- McGlynn Kevin
- McGovern A
- McGuinness Heather
- McInnes I.B.
- McIntosh Jerome
- McIvor Emma
- McIvor K.
- McLeavey Laura
- McMahon A.
- McMahon Michael J.
- McMorrow L
- Mcnally T
- McNarry M
- McNeill J
- McQueen Alison
- McShane H.
- Mears Chloe
- Megson Clare
- Megson Sharon
- Mehta P
- Meiring J
- Melling Lucy
- Mencias Mark
- Menke Ricarda
- Menzies Daniel
- Merida Morillas Marta
- Michael Alice
- Miiler K
- Miller Christopher A
- Miller Karla
- Milligan L.
- Mills Clare
- Mills G
- Mills N.L.
- Milner L
- Misra S
- Mitchell J.
- Mohamed Abdelrahman
- Mohamed Noura
- Mohammed S.
- Molyneaux P.L.
- Monteiro Will
- Moriera Silvia
- Morley Anna
- Morrison Leigh
- Morriss R
- Morrow A.
- Moss Alastair J
- Moss P
- Motohashi K
- Msimanga N
- Mukaetova-Ladinska Elizabeta
- Munawar Unber
- Murira Jennifer
- Nanda U
- Nassa Heeah
- Nasseri Mariam
- Nathu Rashmita
- Neal A
- Needham Robert
- Neill Paula
- Neubauer Stefan
- Newby D E
- Newell Helen
- Newman J
- Newman Tom
- Newton-Cox A
- Nichols Thomas E
- Nicholson T.
- Nicoll Debby
- Nikolaidis Athanasios
- Nikolaidou Chrysovalantou
- Nolan C.M.
- Noonan Matthew J.
- Norman C
- Novotny Petr
- Nunag Jose Lloyd
- Nwafor Lorenza
- Nwanguma Uchechi
- Nyaboko J
- O'Brien Caitlin
- O'Brien Linda
- O'Donnell K
- O'Regan Declan P
- Odell Natasha
- Ogbole Godwin
- Ogg G.
- Olaosebikan Olaoluwa
- Oliver Catherine
- Omar Zohra
- Openshaw Peter J.M.
- Orriss-Dib Lorna
- Osborne Lynn
- Osbourne Rebecca
- Ostermann Marlies
- Overton Charlotte
- Owen J.
- Oxton J
- Pack Jamie
- Pacpaco Edmund
- Paddick S.
- Painter Sharon
- Pakzad A
- Palmer Sue
- Papineni Padmasayee
- Paques K
- Paradowski Kerry
- Pareek Manish
- Parekh Dhruv
- Parfrey H
- Pariante C.
- Parker S
- Parkes M.
- Parmar J
- Patale Sheetal
- Patel B.
- Patel Manish
- Patel Suhani
- Pattenadk Dibya
- Pavlides M.
- Payne Sheila
- Pearce Lorraine
- Pearl John E
- Peckham D.
- Pendlebury Jessica
- Peng Yanchun
- Pennington Chris
- Peralta Ida
- Perkins Emma
- Peterkin Z
- Peto T.
- Petousi Nayia
- Petrie J
- Pfeffer Paul
- Phipps Janet
- Piechnik Stefan K
- Pimm John
- Piper Hanley K.
- Pius R
- Plant Hannah
- Plein Sven
- Plekhanova Tatiana
- Plowright Megan
- Poinasamy Krisnah
- Polgar Oliver
- Poll L.
- Popescu Iulia
- Porter Joanna C
- Porter Julie
- Portukhay Sofiya
- Powell Natassia
- Prabhu A.
- Pratt James
- Price Andrea
- Price Carly
- Price Claire
- Price D.
- Price L
- Price L.
- Prickett A
- Prosper Sabrina
- Pugmire S.
- Quaid Sheena
- Quigley Jackie
- Quint Jennifer
- Qureshi H
- Qureshi I N
- Radhakrishnan K.
- Rahman Najib M.
- Ralser M
- Raman Betty
- Ramos Albert
- Ramos Hazel
- Rangeley Jade
- Rangelov B
- Ratcliffe L
- Ravencroft Phillip
- Reddington A
- Reddy A
- Reddy R.
- Redfearn H
- Redwood Dawn
- Reed Annabel
- Rees Meryl
- Rees Tabitha
- Regan Karen
- Reynolds W
- Ribeiro Carla
- Richards A.
- Richardson Emma
- Richardson Matthew
- Rivera-Ortega P.
- Roberts K.
- Robertson E.
- Robinson E
- Robinson Leanne
- Roche Lisa
- Roddis C
- Rodger J
- Rogers Natalie
- Ross Alexandra
- Ross Gavin
- Rossdale J.
- Rostron A
- Rowe Anna
- Rowland A
- Rowland J.
- Rowland Matthew J.
- Rowland-Jones Sarah L
- Roy K
- Roy Maura
- Rudan I
- Russell Emily
- Russell Richard
- Saalmink Gwen
- Sabit Ramsey
- Sage E.K.
- Samakomva T
- Samani Nilesh
- Samat Azlan Helmy A
- Sampson Claire
- Samuel Katherine
- Samuel R
- Sanders Zeena-Britt
- Sanderson Amy
- Sapey E
- Saralaya Dinesh
- Sargant J
- Sarginson C
- Sass T
- Sattar N
- Saunders Kathryn
- Saunders Laura C
- Saunders Peter
- Saunders Ruth M
- Savill Heather
- Saxon W.
- Sayer A.
- Schronce J.
- Schwaeble W
- Scott Janet T.
- Scott Kathryn
- Selby N.
- Semple Malcolm G.
- Sereno Marco
- Sewell Terri Ann
- Shah Ajay M
- Shah K.
- Shah P.
- Shankar-Hari M
- Sharma M
- Sharpe C.
- Sharpe M.
- Shashaa Sharlene
- Shaw Alison
- Shaw Karen
- Shaw V.
- Sheikh Aziz
- Shelton Sarah
- Shenton Liz
- Shevket K.
- Shikotra Aarti
- Short J
- Siddique Sulman
- Siddiqui Salman
- Sidebottom J
- Sigfrid L
- Simons G
- Simpson J.
- Simpson Neil
- Singapuri Amisha
- Singh Claire
- Singh Sally J
- Singh Suver
- Sissons D
- Skeemer J
- Slack Katie
- Smith Andrew
- Smith D.
- Smith Jacqui
- Smith Laurie
- Smith Nikki
- Smith Stephen
- Smith Susan
- Soares M
- Solano Teresa S
- Solly Reanne
- Solstice A.R.
- Soulsby T
- Southern David
- Sowter D
- Spears M
- Spencer L G
- Speranza Fabio
- Stadon Louise
- Stanel S
- Steeds Rick
- Steele N
- Steiner Mike
- Stensel D.
- Stephens G
- Stephenson Lorraine
- Stern M
- Stewart I
- Stimpson R
- Stockdale Sue
- Stockley J
- Stoker Wendy
- Stone Roisin
- Storrar Will
- Storrie Andrew
- Storton Kim
- Stringer E
- Strong-Sheldrake Sophia
- Stroud Natalie
- Subbe Christian
- Sudlow C L
- Suleiman Z
- Summers C
- Summersgill C
- Sutherland Debbie
- Sykes D.L.
- Sykes R.
- Talbot Nick
- Tan Ai Lyn
- Tarusan Lawrence
- Tavoukjian Vera
- Taylor Abigail
- Taylor Chris
- Taylor Jessica
- Te Amelie
- Tedd H.
- Tee Caroline
- Teixeira J
- Tench Helen
- Terry Sarah
- Thackray-Nocera Susannah
- Thaivalappil Favas
- Thamu B
- Thickett D
- Thomas Andrew K.
- Thomas Caradog
- Thomas David C.
- Thomas S.
- Thomas-Woods T.
- Thompson A A Roger
- Thompson T
- Thornton T
- Thorpe M
- Thwaites Ryan S.
- Tilley Jo
- Tinker N
- Tiongson Gerlynn F
- Tobin Martin
- Tomlinson Johanne
- Tong C
- Toshner Mark
- Touyz R.
- Treibel Thomas A
- Tripp K.A.
- Tunnicliffe Elizabeth M.
- Turnbull A
- Turner E
- Turner Kim
- Turner Sarah
- Turner Victoria
- Turney Sharon
- Turtle Lance
- Turton Helena
- Ugoji Jacinta
- Ugwuoke R
- Upthegrove R
- Valabhji J.
- Ventura M
- Vere Joanne
- Vickers Carinna
- Vinson B
- Wade Elaine
- Wade Phillip
- Wain Louise V
- Wainwright Tania
- Wajero Lilian O.
- Walder S
- Walker S
- Walker S.
- Wall E
- Wallis T
- Walmsley S
- Walsh J.A.
- Walsh S.
- Warburton Louise
- Ward T J C
- Warwick Katie
- Wassall Helen
- Waterson Samuel
- Watson Ekaterina
- Watson James
- Watson L.
- Webster M
- Weir-McCall Jonathan R
- Welch C
- Welch H.
- Welsh B.
- Wessely S.
- West Sophie
- Weston Heather
- Wheeler H
- White Sonia
- Whitehead Victoria
- Whitney J.
- Whittaker S
- Whittam Beverley
- Whitworth V
- Wight A
- Wild James M
- Wilkins M.
- Wilkinson D
- Williams B
- Williams Jenny
- Williams N
- Williams Nick
- Williams-Howard S.A.
- Willicombe M.
- Willis Gemma
- Willoughby J
- Wilson Ann
- Wilson D
- Wilson Imogen
- Window Nicola
- Witham M.
- Wolf-Roberts Rebecca
- Wood Chloe
- Woodhead F
- Woods Janet
- Wootton Daniel G.
- Wormleighton J
- Worsley J.
- Wraith D
- Wrey Brown Caroline
- Wright C.
- Wright L
- Wright S.
- Wyles J.
- Wynter Inez
- Xie Cheng
- Xu M
- Yasmin Najira
- Yasmin S
- Yates Tom
- Yip K P
- Young A.
- Young B.
- Young Susan
- Yousuf A J
- Zawia Amira
- Zeidan Lisa
- Zhao Bang
- Zheng Bang
- Zongo O.
- Publication venue
- Elsevier
- Publication date
- 22/09/2023
- Field of study
Introduction:
The multiorgan impact of moderate to severe coronavirus infections in the post-acute phase is still poorly understood. We aimed to evaluate the excess burden of multiorgan abnormalities after hospitalisation with COVID-19, evaluate their determinants, and explore associations with patient-related outcome measures.
Methods:
In a prospective, UK-wide, multicentre MRI follow-up study (C-MORE), adults (aged ≥18 years) discharged from hospital following COVID-19 who were included in Tier 2 of the Post-hospitalisation COVID-19 study (PHOSP-COVID) and contemporary controls with no evidence of previous COVID-19 (SARS-CoV-2 nucleocapsid antibody negative) underwent multiorgan MRI (lungs, heart, brain, liver, and kidneys) with quantitative and qualitative assessment of images and clinical adjudication when relevant. Individuals with end-stage renal failure or contraindications to MRI were excluded. Participants also underwent detailed recording of symptoms, and physiological and biochemical tests. The primary outcome was the excess burden of multiorgan abnormalities (two or more organs) relative to controls, with further adjustments for potential confounders. The C-MORE study is ongoing and is registered with ClinicalTrials.gov, NCT04510025.
Findings:
Of 2710 participants in Tier 2 of PHOSP-COVID, 531 were recruited across 13 UK-wide C-MORE sites. After exclusions, 259 C-MORE patients (mean age 57 years [SD 12]; 158 [61%] male and 101 [39%] female) who were discharged from hospital with PCR-confirmed or clinically diagnosed COVID-19 between March 1, 2020, and Nov 1, 2021, and 52 non-COVID-19 controls from the community (mean age 49 years [SD 14]; 30 [58%] male and 22 [42%] female) were included in the analysis. Patients were assessed at a median of 5·0 months (IQR 4·2–6·3) after hospital discharge. Compared with non-COVID-19 controls, patients were older, living with more obesity, and had more comorbidities. Multiorgan abnormalities on MRI were more frequent in patients than in controls (157 [61%] of 259 vs 14 [27%] of 52; p<0·0001) and independently associated with COVID-19 status (odds ratio [OR] 2·9 [95% CI 1·5–5·8]; padjusted=0·0023) after adjusting for relevant confounders. Compared with controls, patients were more likely to have MRI evidence of lung abnormalities (p=0·0001; parenchymal abnormalities), brain abnormalities (p<0·0001; more white matter hyperintensities and regional brain volume reduction), and kidney abnormalities (p=0·014; lower medullary T1 and loss of corticomedullary differentiation), whereas cardiac and liver MRI abnormalities were similar between patients and controls. Patients with multiorgan abnormalities were older (difference in mean age 7 years [95% CI 4–10]; mean age of 59·8 years [SD 11·7] with multiorgan abnormalities vs mean age of 52·8 years [11·9] without multiorgan abnormalities; p<0·0001), more likely to have three or more comorbidities (OR 2·47 [1·32–4·82]; padjusted=0·0059), and more likely to have a more severe acute infection (acute CRP >5mg/L, OR 3·55 [1·23–11·88]; padjusted=0·025) than those without multiorgan abnormalities. Presence of lung MRI abnormalities was associated with a two-fold higher risk of chest tightness, and multiorgan MRI abnormalities were associated with severe and very severe persistent physical and mental health impairment (PHOSP-COVID symptom clusters) after hospitalisation.
Interpretation:
After hospitalisation for COVID-19, people are at risk of multiorgan abnormalities in the medium term. Our findings emphasise the need for proactive multidisciplinary care pathways, with the potential for imaging to guide surveillance frequency and therapeutic stratification
Seed Size, Sediment, and Spatial Heterogeneity: Post-Flood Species Coexistence in Dryland Riparian Ecosystems
- Author
- A Bonis
- AA Sher
- AC Grundy
- AE Magurran
- AG Valk van der
- AJ Baxter
- AL Angert
- Andrea F. Hazelton
- AT Moles
- CM Levine
- DA Coomes
- DE Goldberg
- DH Wardrop
- G Galindez
- HL Moggridge
- J Silvertown
- JA Boudell
- JA Myers
- JC Stromberg
- JC Stromberg
- JC Stromberg
- JE Peterson
- Jere A. Boudell
- JL Harper
- JM Goodson
- JR McBride
- Juliet C. Stromberg
- K Jensen
- K Thompson
- K Tobe
- LA Dittmar
- LA Turnbull
- Lane Butler
- M Andrews
- M Parsons
- M Westoby
- MA Leck
- MA Leck
- MF Merigliano
- MR Leishman
- P Chesson
- PB Reich
- R Seager
- RE Ricklefs
- RE Ries
- RL Walls
- RM Bekker
- S Harrison
- SC Wang
- SJ Xiong
- SJ Xiong
- SM Yarnell
- T Drezner
- TW Jurik
- W Sluis
- WB Langbein
- WL Graf
- WM Mahaney
- WR Osterkamp
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Whole-genome sequencing reveals host factors underlying critical COVID-19
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdelrazik Marwa
- Abdollahi Hamed
- Abdullah T.
- Abecasis Goncalo
- Abedalthagafi M.
- Abel Lynn
- Abernathy C.
- Abraheem Azmeralde
- Abul-Husn Noura S.
- Acquilini D.
- Adams C.
- Adams Emma L.
- Adams K.
- Adamsara Alireza
- Adanini Olurenke
- Adeleye O.
- Adra D.
- Afilalo J.
- Afilalo M.
- Afolabi D.
- Afrasiabi Z.
- Agasou A.
- Agrawal Shruti
- Agüero D.
- Ahmad N.
- Ahmadi Saeideh
- Ahmed A.
- Ahmed Cecilia
- Akeroyd L.
- Akhtar M.N.
- Akinkugbe O.
- Aksentijevich Alexandra
- Al-Afghani H.
- Al-Awdah L.
- Alaamery M.
- Alahmadey Z.Z.
- Alaverdian D.
- Alavere H.
- Albader A.
- Albaiceta G.M.
- Albakri J.K.
- AlBardis H.
- Albeladi M.
- Albesher N.
- Albrich W.
- AlDhawi N.
- Aldridge J.
- Aleagha Afshar Etemadi
- Alexander Peter.
- Alfonso J.
- Alghamdi B.
- Alghamdi J.
- Ali A.
- Ali Altaf
- Ali I.A.M.
- Ali Syamlan
- Aliannejad Rasoul
- Aljawini N.
- AlJohani S.
- Alkwai S.
- Allan A.
- Allan E.
- Allan J.
- Alldis Zoe
- Allen L.
- Allen Meryem
- Allen Schvearn
- Allibone S.
- Allison K.S.
- Allos R.
- Ally S.M.
- AlMalik A.
- Almalki F.
- Almohammed I.
- Almutairi M.
- Alotaibi S.
- Alowayn A.M.
- Alqahtani S.
- Alqubaishi F.
- Alrashed M.
- Alshareef A.
- Alsolm E.
- Alswailm M.
- Altabaibeh A.
- Alvaro A.
- AlZahrani D.
- Amin V.
- Amirsavadkouhi Ali
- Amitrano Sara
- Anastasescu E.
- Anderson F.
- Anderson J.
- Anderson Madeleine
- Anderson Peter
- Anderson S.
- Anderson S.
- Anderson T.
- Andolfo I.
- Andretta F.
- Andreucci E.
- Andrew Angela
- Andrew B.
- Andrew Gratrix
- Andrews E.
- Andrews Shea J.
- Anedda F.
- Anemoli V.
- Annis A.
- Antcliffe David
- Antinori Andrea
- Antoni M.D.
- Anumakonda V.
- Apetri E.
- Aquino Maia
- Arabi Y.M.
- Aravindan Latha
- Arbane Gill
- Archer Katie
- Arden T.
- Arias Sonia Sousa
- Arif S.
- Armstrong Jacob
- Armstrong Lisa
- Armstrong Ruth
- Arning N.
- Arnold Sophie
- Arranz MarÃa Jesús
- Arribas E.
- Artuso R.
- Arumugam Prabhu
- Ascolillo Steven
- Ashraf Saima
- Ashton L.
- Aslibekyan S.
- Astin-Chamberlain Raine
- Atkinson E.G.
- Attwood B.
- Aucella F.
- Auld D.
- Auld F.
- Austin Karen
- Austin Pauline
- Auton A.
- Ayers A.
- Azarzar S.
- Bachetti T.
- Baikady R.R.
- Baillie John Kenneth
- Baines Balvinder
- Baines D.
- Baines K.
- Baird Yolanda
- Bakthavatsalam Dhanalakshmi
- Balaconis Mary K.
- Baldassarri M.
- Ball C.A.
- Baltzell A.H.
- Bamford A.
- Bamford Peter
- Banach Dorota
- Bancroft Hollie
- Band G.
- Bandini M.
- Bandla Nageswar
- Bano S.
- Baptista David
- Barakeh D.
- Baras Aris
- Baratti S.
- Barber R.
- Barberis L.
- Barbieri C.
- Barclay Lucy
- Bargagli E.
- Barhoush E.
- Barker J.
- Barnes K.C.
- Baroni S.
- Barrett F.
- Barron A.
- Barry P.
- Bartels M.
- Bartley Shauna
- Baruah R.
- Bashyal Archana
- Basikolo C.
- Bassetti M.
- Bastion V.
- Bates H.
- Bates Michelle
- Batini Chiara
- Battle Ceri
- Bauchmuller K.
- Baxter N.
- Baya N.
- Bayo L.A.
- Beadle Jane
- Bean S.
- Beaumont K.
- Beavis S.
- Beck A.
- Beckmann Noam D.
- Bedini J. L.
- Bee Catherine E.
- Beech E.
- Beech Valerie
- Beekes M.
- Beesley K.
- Begg Colin
- Beguin Y.
- Behan T.
- Beith C.M.
- Belagodu Zakaula
- Belbin Gillian Morven
- Belfield H.
- Belhaj Y.
- Beligni G.
- Belisle A.
- Bell D.
- Bell G.
- Bell M.
- Bell S.
- Bellamy Mary
- Belli M.A.
- Bellini A.
- Bellwood R.
- Below Jennifer
- Bemand T.
- Benetti E.
- Benham Leonie
- Bennett D.
- Bennett Sara
- Bentley David
- Bentley M.
- Benyon S.
- Beranova E.
- Bercades G.
- Bergantini L.
- Bergomi P.
- Berkowitz Nathan
- Bernardo D.
- Bevan E.
- Bewley J.
- Bhatia Nikhil
- Bhatterjee Ravi
- Bhuie Parminder
- Bi R.
- Biagio A.D.
- Bianchi F.
- Bibert S.
- Bibi Fatima
- Biddle Jack
- Biggs Heather
- Birch J.
- Birch J.
- Birch Sophie.
- Birchall K.
- Birchall K.
- Bird S.
- Birkinshaw Isobel
- Birt M.
- Biscarini F.
- Black E.
- Black K.
- Blackledge B.
- Blackman H.
- Blakemore H.
- Blay Natalia
- Blow Sara
- Blunt M.
- Board S.
- Bochud P.Y.
- Bociek Aneta
- Boezen M.
- Boillat N.
- Bokhari M.
- Bolton Matthew
- Bolton Rachel
- Bonner Stephen
- Booker L.
- Borislavova B.
- Borra Catherine
- Botello A.
- Botfield Liam
- Bottà G.
- Bouab M.
- Bough L.
- Boughton A.P.
- Bowes A.
- Bowles Ruth
- Boyle P.
- Boyle R.
- Boz Ceilia
- Bradford Y.
- Bradley C.
- Bradley P.
- Bradley-Potts Joanne
- Bradshaw Zena
- Brady A.
- Brady M.
- Brady R.
- Brandwood C.
- Branney D.
- Brantwood Craig
- Brassard N.
- Brayne A.
- Brealey D.
- Bremmer P.
- Brenner B.
- Bretherick Andrew D.
- Brett Michael
- Brett Stephen
- Brickell K.
- Bridgett V.
- Brimfield Lutece
- Brinkworth Elaine
- Briton Kate
- Britvan Bari
- Bromley M.
- Brooke Hollie
- Brooks S.
- Brown A.
- Brown Adam
- Brown C.W.
- Brown Ellen
- Brown Joanna
- Bruce M.
- Brumpton Ben M.
- Bruno Raffaele
- Brunton Mark
- Bruttini M.
- Bryant J.
- Bryant S.
- Buckley C.
- Buckley Sarah
- Bunni L.
- Burda D.
- Buring Julie E
- Burn I.
- Burnett C.
- Burns K.
- Burt K.
- Burtenshaw Andrew
- Burton Maudrian
- Busani S.
- Bussotti M.
- Butcher D.
- Butler Aaron
- Butler Joanna
- Butler S.
- Butler-Laporte G.
- Butterworth A.S.
- Butterworth-Cowin N.
- Button H.
- Buxbaum Joseph D
- Cabrelli Louise
- Cagova L.
- Caldarelli G.P.
- Callaghan Marie
- Callier S.
- Cameli Paolo
- Campbell Archie
- Campbell Archie
- Campbell Helen
- Campbell Rachael
- Campbell Suzanne
- Campos Sara
- Camsooksai J.
- Canaccini A.
- Cantarini L.
- Cantor M.N.
- Capasso M.
- Capitani K.
- Cappelli S.
- Capps N.
- Carbral-Ortega L.
- Carella M.
- Carey D.J.
- Carmody Margaret
- Carmody S.
- Carnahan M.
- Carreras A.
- Carriero M.L.
- Carter A.
- Carter David
- Carter E.
- Carter Joseph
- Carter S.
- Carungcong J.
- Casey Matt
- Castaño-Vinyals G.
- Castelli F.
- Castle K.
- Castori M.
- Caswell Melanie
- Catena E.
- Caterson Jess
- Cathcart Susanne
- Catlow L.
- Caulfield Mark J.
- Cavazza Anna
- Cawley Kathryn
- Cawthron K.
- Ceri S.
- Chablani M.
- Chadbourn Indra
- Chamnanphon Monpat
- Chan Georgia
- Chan R.
- Chandler B.
- Chang Xiao
- Chapman Susan
- Chariyavilaskul Pajaree
- Charles B.
- Charlesworth Ruth
- Charney Alexander W.
- Charnock R.
- Chasman D.I.
- Chassé M.
- Chaudhary Kumardeep
- Chavan S.
- Cheema Yusuf
- Chen Hung-Hsin
- Chen Jiantao
- Cheng N.
- Cherian Shiney
- Chetam L.
- Chetruengchai Wanna
- Cheyne C.
- Childs D.
- Chittoor G.
- Cho Judy H.
- Cho K.
- Choi Sam
- Choudhury Yasmin
- Christine Almaden-Boyle None
- Chukkambotla Srikanth
- Churchhouse C.
- Chwialkowska Karolina
- Claassen S.
- Clamp Sarah
- Clapham M.
- Claringbould A.
- Clark Amy
- Clark M.
- Clark Martynn
- Clark Richard
- Clark Sarah
- Clark Victoria
- Clarke D.
- Clarke N.
- Clarkson M.
- Clayton Sarah
- Clement Ian
- Clements S.
- Coates Charlotte
- Cockrell Maeve
- Coetzee S.
- Coghlan Phoebe
- Coignet M.
- Coiro G.
- Coker D.
- Cole J.
- Cole J.
- Cole Stephen
- Coleman Dabheoc
- Coles Holly
- Colley Julie
- Collier D.
- Collier David
- Collins Amy
- Collins Brett L.
- Collins C.
- Collins E.
- Collins E.
- Collins Katy
- Collins Rebecca
- Collis M.
- Colobrán R.
- Colombo R.
- Combes Edward
- Connolly K.
- Conticini E.
- Convery K.
- Conyngham J.A.
- Cooper J.
- Cooper L.
- Corcoran Eleanor
- Cordioli Mattia
- Cornell S.
- Corral M.A.
- Corridi M.
- Cortés B.
- Cosgrove D.
- Cosier T.
- Cossarizza A.
- Cother Naiara
- Coto E.
- Coton Z.
- Coulding Martina
- Coutts Audrey
- Coventry T.
- Coviello D.A.
- Cowley A.
- Cowley Nicholas
- Cowton Amanda
- Cox Amber
- Coyle Judy
- Craig J.
- Crawley R.
- Creagh-Brown B.
- Crew A.
- Crickmore V.
- Crisp N.
- Criste Kristine
- Cristiano D.
- Croci L.
- Croci S.
- Croft Maria
- Crook D.W.
- Crooks K.
- Crotti L.
- Crowe Rebecca
- Crowley Maria
- Cruz C.
- Cullell Natalia
- Cullum Louise
- Cunningham A.
- Cunningham M.
- Cupitt Jason
- Curgenven H.
- Cusack Rebecca
- Cusick C.
- Cutler Sean
- Cárcel-Márquez Jara
- D'Alessandro M.
- D'Mellow Kenton
- D'Sylva S.
- Da Gloria Edna Fernandes
- Daga S.
- Daglish Jacqueline
- Dale K.
- Dale S.
- Dalmau D.
- Daly Mark J.
- Daly Zoe
- Dalziel Jack
- Dance A.
- Danesh J.
- Daniel A.
- Daniel Priya
- Daniels A.
- Darcis G.
- Dark P.
- Darlington K.
- Das Mihaela
- Das Sukamal
- Dasgin Jo
- Daubney Esther
- Davey Miriam
- David B.
- Davidson Neil
- Davies C.
- Davies E.
- Davies F.
- Davies G.
- Davies K.
- Davies L.
- Davies Michelle
- Davies R.
- Davis Caroline
- Davison Chloe
- Dawson Deborah
- Dawson J.
- Day Nicky
- Daya M.
- de Almeida Martins L.G.
- de Cid R.
- de Geus E.
- de Gordoa Laura Ortiz-Ruiz
- de la Cal-Sabater P.
- De Neef M.
- De Vivo O.
- Deacon Bethan
- Dearden Joy
- Death Y.
- Debreceni G.
- DeDiego M.L.
- Deelen P.
- Deery J.
- Dei S.
- Delgado Carlos Castro
- Demetriou C.
- Denmade C.
- Dennis C.
- Dent K.
- Dent Martin
- Depante Maria
- Desanctis E.
- Dexter Catherine
- Di Angelantonio Emanuele
- Di Domenico P.
- Di Pietro M.
- Dietl Beatriz
- Digby Brian
- Digby Stephen
- Ding Lijun
- Djeugam B.
- Do Ron
- Dobaño C.
- Doble P.
- Dobson Emma
- Doddato G.
- Dodds Steve
- Domingo C.
- DomÃnguez-Mayoral A.
- Donaldson A.
- Donaldson D.
- Donati A.
- Donlon S.
- Donnachie J.
- Donne B.
- Donnelly K.
- Donnelly Lorna
- Donner K.
- Donnison P.
- Donovan Sally
- Dooks E.
- Doonan R.
- Dore R.
- Dormand N.
- Douglas K.
- Downes Charlotte
- Drummond Andy
- Duberly Stephen
- Duffield Joseph
- Duffin D.
- Duffy Katharine
- Duffy Stacey
- Duncan E.
- Duncan Esther
- Duncan T.
- Dunmore Charlie
- Durand M.
- Durga L.
- Durie Alison
- Durrans L.J.
- Durrant Georgia
- Duskova M.
- Dykes Joseph
- Eapen B.
- Earle S.G.
- Eastgate-Jackson C.
- Easthope Amy
- Easton J.
- Ebano Patrizia
- Eckbad C.
- Edmond I.
- Edwards M.
- Efford G.
- Egan Jasmine
- Eid Mohammed A.
- El-Jawhari Jehan J.
- El-Lawaty Walaa M.
- El-shanshory Mohamed R.
- El-Sherbiny Yasser M.
- Elgar Greg
- Elhadidy Tamer A.
- Elhassan Munzir
- Elliott K.
- Elliott Katherine S.
- Elliott Paul
- Ellis Hannah
- Elnagdy Marwa H.
- Elsaadany M.
- Elston Kay
- Eltayeb A.
- Eltoukhy Madonna M.
- Emiliozzi A.
- English K.
- Erard V.
- Esko T.
- Esparza-Gordillo J.
- Evitts J.
- Ezeobu Obiageri
- Fabbiani M.
- Fagan Andrew
- Falcone M.
- Fallerini C.
- Farnell-Ward Sarah
- Farquhar F.
- Farré X.
- Farzad Z.
- Faulkner B.
- Faulkner Maria
- Fava F.
- Fawkes Angie
- Fawns-Ritchie Chloe
- Fawzy M.S.
- Fearby M.
- Felemban W.A.
- Felton Timothy
- Feng Y.C.A.
- Ferguson S.
- Feri M.
- Fernandes K.
- Fernandes Rita
- Fernandez Ziortza
- Fernandez-Cadenas Israel
- Fernandez-Roman Jaime
- Ferreira Manuel A.R.
- Ferri C.
- Fidler K.
- Filipe H.
- Filshtein-Sonmez T.
- Finch C.
- Findlay L.
- Fine Christopher
- Finer S.
- Finernan Paul
- Finn J.
- Finn S.
- Finney Clare
- Finucane H.
- Fiorentino G.
- Fisher Emma
- Fiz-López A.
- Flanagan R.
- Fletcher Jo
- Flint N.
- Fofano A.
- Folkes Linda
- Foote D.
- Ford A.
- Forgetta V.
- Forsey M.
- Foster L.
- Fotiadis Stavros
- Fottrell-Gould D.
- Fourman Max Head
- Fowler S.
- Fowler T.
- Fowler Tom A.
- Fox C.
- Fox Heather
- Fox Jonathan
- Franchi F.
- Francisci D.
- Franco G.
- Franke George
- Franke L.
- Frankham J.
- Frater Alasdair
- Frediani B.
- Free Robert C.
- Frippiat F.
- Frise Matthew
- Frithiof R.
- Frost Victoria
- Frullanti E.
- Fuller Bridget
- Furini S.
- Furlong Anita
- Furniss James
- Gabbi C.
- Gabrieli A.
- Gaddis Michael
- Gales A.
- Gallagher Bernadette
- Galván-FemenÃa I.
- Ganesan Arunkumar
- Ganna Andrea
- Garcia S.M.
- Garcia-Aymerich Judith
- GarcÃa-Clemente M.
- GarcÃa-Madrona S.
- Gardner Amy
- Garg Atul
- Garland Z.
- Garner L.
- Garrioch S.
- Gascoyne R.
- Gass M.C.
- Gatti F.
- Gay Bethan
- Gaylard J.
- Gaziano J.M.
- Geary T.
- Gellamucho Minnie
- Gemmell Lisa
- Gendall E.
- Genetu R.
- George Aparna
- George L.
- Georges M.
- Gettler Kyle
- Gherman Anca
- Ghosh A.
- Ghosh B.
- Giannattasio F.
- Gibson Sian
- Gignoux C.R.
- Gilbert K.
- Gilchrist Tammy
- Giliberti A.
- Gill Jaspret
- Gill M.
- Giorli A.
- Giot J.B.
- Girach Rumanah
- Girardis M.
- Girshick A.
- Glasgow Susannah.
- Glass L.
- Gledhill L.
- Glessner J.R.
- Glessner Joseph T.
- Goddard Peter
- Goddard Wendy
- Goff E.
- Gofflot S.
- Golden David
- Golder Kim
- Golding Hannah
- Goldstein J.I.
- Golightly Alisa
- Gomez J.
- Gomez Rachel
- Gondo P.
- González-Villa E.
- Goodchild Drew
- Goodsell J.
- Goodwin Emma
- Gopal S.
- Gordon Anthony
- Gordon E.
- Gori Marco
- Gorman C.
- Graham C.
- Grassi D.
- Gratrix A.
- Grau Neus
- Grauslyte Lina
- Green J.
- Green R.C.
- Greer Sandra
- Gregory J.
- Greig J.
- Griffin D.
- Griffiths C.J.
- Griffiths Fiona
- Grimmer L.
- Grip J.
- Guarnaccia A.
- Gude Estefania Treus
- Guerin J.
- Guerrini S.
- Guidelli L.
- Guindo-Martinez M.
- Guiot J.
- Gulati A.
- Gumbrill B.
- Gummadi M.
- Guntz J.
- Gupta A.
- Gupta R.
- Gurasashvili Jana
- Gurr L.
- Guturu H.
- Guyatt Anna L.
- Guzman C.
- Hadebe B.
- Hafezi Katarzyna
- Hairsine B.
- Hakonarson H.
- Halawani R.T.
- Haldeos Anne
- Hales D.
- Halkes M.
- Hall K.
- Halls Rosslyn
- Hambrook G.
- Hamilton David O.
- Hamilton Debbie
- Hammerton K.
- Hanley S.
- Hanratty H.
- Hanson H.
- Hanson K.
- Hansson Karen
- Haq Risna
- Hard K.
- Harden L.
- Harding P.
- Hardy J.
- Harerimana Nadia V.
- Harford Rachel
- Hargreaves Jeanette
- Harling Rhiannan
- Harper R.
- Harrington K.
- Harris C.
- Harris J.
- Harris J.R.
- Harris N.
- Harrison Abiola
- Harrison Alison
- Harrison L.
- Harrison W.
- Harthi F.A.
- Hartley Janice
- Hartridge Pippa
- Harvey A.
- Hasanato R.
- Hass I.
- Hatton J.
- Hawcutt D.
- Hawes J.
- Hay A.
- Hayes Anne
- Hayes K.
- Hayman Mel
- Hays C.
- Hayward Caroline
- Hazelton T.
- Headlam Evie
- Heeney E.
- Hegazy Mohamed A.F.
- Helgeland Ø.
- Hellen Mybaya
- Helm David
- Henderson S.
- Hendry Ross
- Hendry Sara Clohisey
- Henry D.
- Hensen K.
- Herdman-Grant Rosaleen
- Heron Anne Emma
- Hesseldon L.
- Hewitt C.
- Hey S.
- Hibbert M.
- Hierons S.
- Hiester Liam L.
- Higham A.
- Highgate J.
- Hijazi Muhammad
- Hill H.
- Hill M.
- Hilldrith A.
- Hilltout P.
- Hilton Mary
- Hindale J.
- Hinds Charles
- Hirankarn Nattiya
- Ho Y.L.
- Hobden Gillian
- Hobrok M.
- Hodgkiss T.
- Hodgson Luke
- Hoggart Clive
- Holcombe H.
- Holding Kathleen
- Holdroyd K.
- Holland M.
- Hollox Edward J.
- Home M.
- Hong E.L.
- Hope Dave
- Hope S.
- Hopkins Bridget
- Horby Peter
- Hormis A.
- Horner D.
- Hornsby James
- Horowitz Julie E.
- Horsley E.
- Hosseini Abdolmajid
- Hottenga J.J.
- Houlden H.
- Housley K.
- Houston G.
- Howard Kate
- Howe Gwenllian Sera
- Howie L.
- Howle R.
- Howlett A.
- Hruska M.
- Huang Q.Q.
- Huckins Laura M.
- Hudig L.
- Hudson A.
- Huffman J.E.
- Hughes Alistair
- Hughes G.
- Hughes R.A.
- Hugill Keith
- Hull R.
- Hulme Jonathan
- Hultström M.
- Humphrey C.
- Humphreys S.
- Hunt J.
- Hunt Jodie
- Hunt K.A.
- Hurford F.
- Hurt William James
- Hussain Musarat
- Hussain Samia
- Hussain Y.
- Hutter J.
- Hutton Paula
- Huynen P.
- Hveem K.
- Iglesias L.L.
- Ikram M.A.
- Imeson-Wood J.
- Ingham Joanne
- Inweregbu K.
- Iolascon A.
- Ireland Jane
- Irvine V.
- Ishaq T.
- Itan Yuval
- Jackson Matthew
- Jackson P.
- Jackson Y.
- Jackson-Lawrence K.
- Jacob R.
- Jacques J.
- Jacques Nicola
- Jakkula S.
- Jantarabenjakul Watsamon
- Jardine C.
- Jarmain J.
- Jarman C.
- Javaid A.
- Jeffrey Helen
- Jenkins S.
- Jenkins Samuel
- Jennings C.
- Jerome Ellen
- Jetha C.
- Jha Rajeev
- Jhanji S.
- Jim R.
- Jiménez-Xarrié Elena
- Joe W.
- Joefield Teishel
- John Catherine
- Johnson Emily
- Johnson Laura
- Johnson R.
- Johnston Brian
- Jones C.
- Jones D.
- Jones G.A.L.
- Jones J.
- Jones Jessica
- Jones Megan
- Jones Oliver
- Jones Rhianna
- Jones S.
- Jones Tim Owen
- Jordan Daniel
- Jose S.
- Joseph Anna
- Joseph Rosane
- Joseph Sibet
- Josyula N.S.
- Joy Rosie
- Jude Edward
- Jung J.
- Justice Anne
- Kadiri Salma
- Kaliappan A.
- Kallaste A.
- Kallon Delordson
- Kamdar D.
- Kamundi Charlotte
- Kanai Masahiro
- Kannan T.
- Kanu Rebecca
- Kapoor R.
- Karczewski K.J.
- Karjalainen Juha
- Karlson E.W.
- Karp Avromie
- Karthik K.
- Kasipandian V.
- Kassam Jamila
- Katary A.
- Kaufmann D.E.
- Kaul S.
- Kaunisto M.
- Kausar R.
- Kay Andrea
- Kayani A.
- Kaye C.
- Kaye D.
- Kazi Aayesha
- Keating Liza
- Keating Sean
- Keenan N.
- Keenan S.
- Keith Sara
- Keller Katherine
- Kelly D.
- Kelly F.
- Kelly S.
- Kelsall Olivia
- Kennard-Holden G.
- Kennedy-Hay S.
- Kenny Eimear E.
- Kent Alisa
- Kent H.
- Kent Melanie
- Kerr Shona M.
- Keshet-Price J.
- Khade Reena
- Khafaga Walid T.
- Khaliq Waqas
- Khan Meherunnisa
- Khattab A.K.
- Khera Jacyntha
- Kibutu F.
- Kimchi N.
- Kinch Ashley
- King B.
- King D.
- King Kirsten
- King Laura
- Kingsley Clare
- Kirkby A.
- Kisand K.
- Kitson R.
- Kivinen K.
- Klaric Lucija
- Knight A.
- Knight Julian
- Knight S.
- Knighton Abigail
- Knights E.
- Knowles K.
- Koelling N.
- Kogevinas M.
- Kolakaluri L.
- Kong T.
- Koskelainen S.
- Kosmicki Jack A.
- Kousathanas Athanasios
- Krishnamurthy Vinodh
- Kristiansson K.
- Kubisz-Pudelko A.
- Kumar Rita
- Kumar Rohit
- Kumar S.
- Kuravi Aditya
- Laane E.
- Labkowsky Alexander
- Laha S.
- Laisk T.
- Lake V.
- Lamb T.
- Lambermont B.
- Lamond Zoe
- Lancaster N.
- Lancoma-Malcolm Ivone
- Langley Margaret
- Langton H.
- Lankester L.
- Lanting P.
- Latham S.
- Lathrop G.M.
- Latif M.
- Laurent L.
- Law Andy
- Law Dawn
- Law Rachel
- Law Sarah
- Lawton T.
- Lazo Maria
- Leader J.B.
- Lean R.
- Leaver Susannah
- Ledgard C.
- Lee E.
- Lee Paul H.
- Lee S.
- Lee Y.
- LeFaive J.
- Leggett Samantha
- Leigh M.
- Lena F.
- Lenagh B.
- Lennon L.
- Lepage P.
- Lepamets M.
- Levy Tess
- Lewis A.
- Lewis J.
- Lewis T.
- Li B.
- Li K.W.
- Li R.
- Liao Rachel G.
- Liderth S.
- Lidstone-Scott Rebecca
- Liew J.
- Liggett Steven
- Lim Lai
- Lim Rosario
- Lin S.K.
- Lindergard G.
- Ling Lowell
- Linnett V.
- Lipcsey M.
- Lisboa Ana
- Lista M.
- Little J.
- Liyanage K.
- Llucià -Carol Laia
- Loader D.
- Lomas D.
- London Emily
- Long Kate
- Loos Ruth J. F
- Loosley R.
- Lopera E.
- Lorubbio M.
- Lorusso R.
- Love N.
- Loveridge Adam
- Low Emma
- Lozano F.
- Lu W.
- Lubimbi G.
- Lucas A.
- Lucas R.
- Luchi S.
- Ludovisi S.
- Lye A.
- Lyle Amanda
- Lynch Ceri
- Lyon A.
- Lyons C.
- Lyons Marc
- Läll K.
- Léonar P.
- Ma L.
- Mac A.
- Maccacari Elena
- MacCallum N.
- Macgillivray Louise
- MacGoey Patrick
- Macharia I.
- Mackay C.
- Mackintosh K.
- Maclean Alan
- MacMahon M.
- Maggiolo F.
- Magnus P.
- Maharajh A.
- Mahay K.
- Mahenthran M.
- Mahjoob P.
- Mahmoud E.S.
- Mal Hanning
- Malaise O.
- Male Michelle
- Maleady-Crowe Fiona
- Malinauskas Tomas
- Mallinson J.
- Mallon Lewis
- Mamlouk N.
- Mancarella S.
- Mandalà M.
- Mangino M.
- Mangul S.
- Manna Soumendu
- Manso K.
- Manson J.A.E.
- Mantovani S.
- Mapfunde I.
- Maqsood Zahira
- Marani Martyna
- Marcantonio S.
- Marciano C.
- Margalef Jordi
- Margarson Michael
- Mari F.
- Maricic T.
- Marotti Martina
- Marriott C.
- Marriott S.
- Marsden T.
- Marsh C.
- Marsh S.
- Marshall Lucy
- Marshall R.
- Martin A.R.
- Martin D.
- Martin H.C.
- Martin J.
- Martin T.
- Martindale Tim
- Martinelli E.
- Martinez Maria Lopez
- Martinson V.
- Martir G.
- MartÃ-FÃ bregas Joan
- MartÃn-Nalda A.
- MartÃnez A.P.
- Mascarenhas M.
- Masjuan J.
- Maslove David
- Mason D.
- Massadeh S.
- Masucci L.
- Masuko S.
- Masunda B.
- Matapure L.
- Matharu Maninderpal
- Matheson J.
- Mathew B.
- Mathew Jisha
- Matt Roseanna
- Matthews J.
- May Peter
- Mayangao I.
- Mayer A.
- Maynard V.
- Mazzei M.A.
- McAlindon Michael
- McAuley Danny
- McCafferty Sarah
- McCormack L.
- McCormick Jacqueline
- McCormick Joseph B.
- McCormick W.
- McCreath G.
- McCulloch Corrienne
- McCurdy Alex
- McCurdy S.
- McFarland D.
- McGowan J.
- McGregor A.
- McGregor A.
- McGuigan P.J.
- McGuinness H.
- McHugh T.
- McIvor S.
- McKechnie Stuart
- McKenley India
- McKenna E.
- McLaughlan D.
- McMaster Ellie
- McMorrow L.
- McNeela Fiona
- McParland C.
- McParland C.
- McPhail Mark
- Meadows Emma
- Meaney Eoghan
- Medhora J.
- Medina-Gomez C.
- Meghari H.
- Meigs J.B.
- Meikle A.
- Meikle Jen
- Melia D.
- Melling Sarah
- Mellor S.
- Meloni I.
- Melville Julie
- Menatti E.
- Mencarelli M.A.
- Menzies D.
- Menéndez-Valladares P.
- Mepham S.
- Mercader J.
- Mercader J.M.
- Mercer Oliver
- Mercer P.
- Meredith Megan
- Merla G.
- Merwaha E.
- Metcalfe Alexandra
- Metherell S.
- Metsalu K.
- Metspalu A.
- Meuris C.
- Mew L.
- Michael A.
- Michael H.T.
- Michalak-Glinska N.
- Middleton H.
- Milani L.
- Millar Jonathan
- Millar Jonathan E.
- Millen G.
- Milligan B.
- Mills G.H.
- Millward H.
- Milner L.
- Mimbrera A.d.F.
- Miraglia F.G.
- Mirshahi Tooraj
- Misset B.
- Mitchard S.
- Mitchell A.M.
- Mitchelmore Oliver
- Mitra A.
- Moahmed Hanteera S.
- Moghaddam Seyed Behrooz Mohseni
- Mohamed Attia A.S.
- Moncur E.
- Mondelli M.U.
- Monforte A.D.
- Monica M.D.
- Monnery Sonja
- Montagnani F.
- Montaser R.
- Montgomery Hugh
- Moore Faye
- Moore L.S.P.
- Moore Shona C.
- Mooser V.
- Moreno V.
- Moreno-Cuesta Jeronimo
- Morgan Aled
- Morgan J.
- Morino Eriko
- Morrice Kirstie
- Morris A.
- Morris Lucy
- Morris Marcela
- Morris S.
- Morrison A.
- Morrison D.R.
- Moss Stuart
- Mostoles L.
- Motherwell N.
- Moultrie S.
- Moutschen M.
- Moutsianas Loukas
- Msiska Maines
- Mtuwa S.
- Muchenje N.
- Muiño Elena
- Mulcahy Michelle
- Mulla Suleman.
- Mullan D.
- Munt Sheila
- Mupudzi M.
- Murdoch E.
- Murdoch S.
- Murphy A.
- Murphy Carl
- Murphy L.
- Murphy Lee
- Murphy S.N.
- Murphy Sheena
- Mussini C.
- Mutairi A.A.
- Mutch R.
- Mwaura E.
- Mwaura L.
- Márquez L.
- Mägi R.
- Naaber P.
- Naderpour Zeinab
- Nadkarni Girish N.
- Nagra Imrun
- Naisbitt Jay
- Nakanishi T.
- Naranjo Andres
- Nasir Farah
- Nayak Monalisa
- Nazari R.
- Neal Alan
- Neale Benjamin M.
- Nencioni C.
- Neofytos D.
- Netherton K.
- Newell H.
- Newey Luke
- Newman J.
- Newman Tabitha
- Newton M.
- Ng Anthony
- Nguyen Huy
- Niavarani Ahmadreza
- Niblo Kristi
- Nichol Alistair
- Nicholson A.
- Nicholson A.
- Nicol L.
- Niemi Mari E.K.
- Nikitas N.
- Nilaratanakul Voraphoj
- Nilsson Anette.
- Nivard M.
- Nixon R.
- Nkambul L.
- Nkambul Lindokuhle
- Noble Harriet
- Nolan C.
- Norman K.
- Norris John
- Nortcliffe T.
- North J.
- North Kari
- Noto Keith
- Novis C.
- Nown Angela
- Nune A.
- Nussle S.G.
- Nwafor L.
- O'Brien L.
- O'Brien P.
- O'Connell A.M.
- O'Connell S.
- O'Connor Denise
- O'Connor Grainne
- O'Donnell C.J.
- O'Hara M.
- O'Leary R.
- O'Malley L.
- O'Neil Pauline
- O'Neill L.
- O'Reilly Kevin
- O'Reilly Paul
- O'Sullivan S.
- Oakley Naomi
- Oblak M.
- Odam M.
- Odhams Christopher A.
- Oetjens Matthew
- Ogg Bethan
- Ognibene A.
- Okasha Kamal
- Okeefe L.
- Oliveira M.
- Olufuwa Olumide
- Omar Z.
- Oosthuyzen Wilna
- Openshaw Peter
- Ori A.P.S.
- Ostermann Marlies
- Otahal I.
- Oxspring S.
- Paciosi F.
- Packer Richard J.
- Packham S.
- Padden Grace
- Page V.J.
- Pairo-Castineira Erola
- Pakou G.
- Palmer D.S.
- Palmieri M.
- Palotie A.
- Pancrazzi A.
- Panese S.
- Pappa Evita
- Paramsothy Remi
- Parati G.
- Parisi S.G.
- Park D.
- Park L.
- Parker R.
- Parkin J.
- Parkinson Nick
- Parkinson P.
- Parmar C.
- Parravicini P.
- Parris V.
- Parsons P.
- Partha R.
- Partridge R.
- Pasko D.
- Passmore H.
- Patch Christine
- Patel A.
- Patel B.
- Patel B.
- Patel Kamal
- Patel Mital
- Patel Tahera
- Paterson Trevor
- Pathak Gita
- Pathan Nazima
- Pattison N.
- Paul P.
- Pavlovic Milos
- Pawley C.
- Pearson Harriet
- Pearson S.
- Peasgood Emily
- Peloso G.
- Penacerrada M.
- Pendlebury J.
- Penn R.
- Pereira Alexandre C.
- Perez E.F.
- Perez J.
- Perez-Tur J.
- Perkins E.
- Perna R.
- Perola M.
- Perrella A.
- Perry J.
- Peruggia Michael
- Pessina G.
- Pesukova J.
- Peters Cecilia
- Peters M.J.
- Peterson P.
- Petitjean L.
- Petrocelli P.
- Petty Lauren E.
- Pheby Jane
- Philbin Jennifer
- Phillips Claire
- Phillips P.
- Phipps J.
- Phokaew Chureerat
- Phull Mandeep
- Piacentini P.
- Picchiotti N.
- Pickard A.
- Piercy C.
- Pigazzini S.
- Pinnell J.
- Pinoli P.
- Pinto A.M.
- Pinzuti Irene
- Pippard L.
- Pirinen Matti
- Piscopo C.
- Pitts S.
- Planas A.M.
- Player B.
- Pogreban Tatiana
- Pogson David
- Polgar O.
- Polgarova Petra
- Polikowski Hannah
- Polimanti Renato
- Pollard R.
- Polymeropoulos C.
- Polymeropoulos M.H.
- Polymeropoulos V.
- Pongpanich Monnat
- Ponting Chris P.
- Poole Alice
- Popescu M.
- Porteous David J.
- Poscente M.
- Pothecary Carla
- Potla Darsh
- Potoczna D.
- Potts Kathryn
- Poulaka M.
- Poultney U.
- Prady H.
- Prager Kirsty
- Praman K.
- Pratley A.
- Prendergast C.
- Prentice L.
- Preston Stephen
- Preuss Michael
- Price A.
- Price C.
- Price Richard
- Prime Zoe
- Pristopan V.
- Pritchard K.
- Proudfoot N.
- Prout R.
- Prysyazhna Oleksandra
- Przychodzen B.P.
- Pugh R.
- Purewal B.
- Purewal Manjit
- Purohit Dharam
- Purvis S.
- Putchareon Opass
- Puthanakit Thanyawee
- Puusepp M.
- Puxty Alex
- Puxty Kathryn
- Pye K.
- Qiu X.
- Quaid S.
- Queiroz Joana
- Quinn A.
- Quinn H.
- Quinodoz M.
- Quiros-Roldan E.
- Rad L.
- Rader D.
- Rader Daniel J.
- Radford E.
- Radhakrishnan Jayachandran
- Rafaels N.
- Raggi P.
- Ragoussis J.
- Rahmouni S.
- Rai Sabi Gurung
- Raimondi F.
- Raith E.
- Raithatha A.
- Raj M.
- Ramos L.
- Rancan I.
- Rand J.
- Rand K.
- Randell G.
- Ranga Poonam
- Rangarajan H.
- Rankin Tobias
- Ratnam V.
- Rattray A.
- Ravaglia S.
- Rawlik Konrad
- Rawlins John
- Ray S.
- Raynard Dana
- Reddy A.
- Reece-Anthony R.
- Reed A.
- Rees A.
- Rees S.
- Rees Tabitha
- Rehman Hafiz
- Reid K.
- Reimann E.
- Rekha P.
- Rendon Augusto
- Renieri A.
- Reschreiter H.
- Reyes A.
- Reynolds Jessica
- Rezk N.
- Rhead B.
- Rhead K.
- Rhodes Daniel
- Rhodes Joanne
- Rice P.
- Richards J.B.
- Richards Owen
- Richardson N.
- Riches J.
- Riches Katie
- Richmond Anne
- Rico V.
- Ridker P.M.
- Rikunenko R.
- Ringmets I.
- Ripamonti D.
- Ripatti S.
- Rishton Chloe
- Ritchie Marylyn D.
- Ritzema J.
- Riva A.
- Rivers V.
- Rivolta C.
- Rizzi M.
- Rizzo C.L.
- Roberts Belinda
- Roberts G.
- Robinson M.
- Robinson P.
- Robles V.
- Roche L.
- Roche Lisa
- Roche Samantha
- Rodden Natalie
- Roe N.
- Rogers N.
- Rogers P.
- Rogerson K.
- Rogne T.
- Rojo Roceld
- Rojo S.
- Romani D.
- Rooney Kevin
- Rooney L.
- Rooyackers O.
- Rosa A.D.
- Rosaroso Lace
- Rose Alastair
- Rose Steve
- Rossetti B.
- Rostron A.
- Rothwell J.
- Rovere M.T.L.
- Rowan Kathy
- Rowland-Jones S.
- Roy A.
- Roynon-Reed Anna
- Rudkin J.K.
- Ruiz Luong
- Ruiz-Jaén F.
- Runciman N.
- Ruotsalainen S.
- Rusconi S.
- Russell Clark D.
- Russo R.
- Ryan Lucy
- Ryan-Smith Janet
- Saad Samuel
- Sabrina R.
- Saeedi Morteza
- Safieh L.A.
- Saha R.
- Saha Rohit
- Saha Sian
- Sainsbury Hannah
- Salberg A.
- Salciute Erika
- Saleem Malik
- Salehi Shahla
- Salerni L.
- Salib Irene
- Salmi S.
- Salmon Karen
- Salutous D.
- Saluzzio Romina Pepermans
- Samakomva Tinashe
- Samir Amr
- Sampson Julia
- Sanarico M.
- Sanderson A.
- Sandhu Rajdeep
- Sangombe Mirriam
- Sanguinetti M.
- Sarathy V.
- Sargeant Janet
- Sarma G.
- Sarno L.D.
- Sarzi-Braga S.
- Sathe S.
- Satterstrom F.K.
- Saunderson A.
- Saunderson P.
- Sauvage A.S.
- Savill Heather
- Sawaji M.
- Scaggiante R.
- Scala R.
- Scanlon J.
- Schadt Eric E.
- Scherewode J.
- Schiaroli E.
- Scholefield B.
- Schon Katherine
- Schumacher N.
- Schurr E.
- Scolletta S.
- Scott Richard H.
- Scott T.
- Scott Zoe
- Scotton P.G.
- Scriven James
- Sealfon Stuart
- Seaman Rebecca
- Sebra Robert P.
- Seed C.
- Segala F.V.
- Segura T.
- Sell C.
- Sellick K.
- Selvanayagam S.
- Semple OBE Malcolm G.
- Semple Gary
- Senaratne D.
- Serra-Llovich A.
- Serrano-Heras G.
- Serrano-Ruiz A.
- Service J.
- Sesso H.D.
- Shah Nirav
- Shahin Doaa
- Shankar-Hari Manu
- Shanmugasundaram P.
- Sharififard Bahareh
- Shastri A.J.
- Shaw David
- Shaw Douglas M.
- Shaw L.
- Shaw R.
- Shelley B.
- Shelton J.F.
- Shelton S.
- Shen Xia
- Shepardson S.
- Shepherd A.
- Shiel Julian
- Shokkar R.
- Short A.
- Shortt J.
- Shotelersuk Vorasuk
- Shovelton C.
- Shrine Nick
- Shuker Karen
- Siano M.
- Sicat Christine
- Siddiq Afshan
- Silva Pedro
- Sim M.
- Simms Richard
- Simpson K.
- Simpson K.
- Singh Jayaprakash
- Singleton Jo
- Skinner D.
- Slater V.
- Slaughter M.
- Slawson Nicola
- Slevin K.
- Sloan Brendan
- Sloane G.
- Sloofman Laura G.
- Smedley Clare
- Smieszek S.P.
- Smith A.V.
- Smith E.
- Smith J.
- Smith J.
- Smith John
- Smith K.
- Smith L.
- Smith Matthew
- Smith Oliver
- Smith T.
- Smithson Elizabeth
- Smoller J.W.
- Smuts Sara
- Smyth D.
- Smyth M.
- Sobh Ali
- Sodsai Pimpayao
- Soler P.
- Sollesta Kathryn
- Solligard E.
- Solomonson Matthew
- Soranzo N.
- Soriano A.
- Sowter J.
- Spargi G.
- Spector T.D.
- Spencer C.C.A.
- Spencer K.
- Spencer S.
- Spertilli C.
- Spivey M.
- Springle Philippa
- Squeo G.M.
- Sri-Chandana C.
- Srikaran S.
- Stacey A.
- Stammers K.
- Starkopf J.
- Stead R.
- Stella A.
- Stenhouse Andrew
- Stephens D.
- Stephenson E.
- Stephenson L.
- Stevens Christine
- Stevenson L.
- Stewart R.
- Stickley J.
- Stoddard Emma
- Stone S.
- Stones E.
- Stowe B.
- Strachan D.
- Stroud Katerina
- Stroud Natalie
- Stuart Carmel
- Stuckey Alex
- Suardi C.
- Suarez Jose Cebrian
- Subramanian Deepak
- Subramanian G.
- Suchartlikitwong Pintip
- Suh N.
- Sukha A.
- Sukumaran A.
- Suliman B.A.
- Summers Charlotte
- Summers J.
- Sumoy L.
- Sun Y.V.
- Sundar Ashok
- Sundaram Radha
- Sutherland I.
- Sutherland S.B.
- Suttichet Thitima B.
- Swain Andrew
- Sweeney L.
- Sweet K.
- Swets Maaike
- Symon L.
- Symons A.
- Szakmany Tamas
- Szoor-McElhinney Helen
- Tabri J.
- Tacconi D.
- Tadi Hengameh A.
- Tagliavini E.
- Tamm A.
- Tampsett R.
- Taneski Filip
- Tanfoni M.
- Tang Lara
- Tardif N.
- Tariq A.
- Tatham K.C.
- Tavares S.
- Tavecchia L.
- Taylor A.
- Taylor June
- Taylor M.
- Taylor Melanie
- Tebbutt J.
- Templeton Maie
- Tench H.
- Tenesa Albert
- Tetla D.
- Texeira Joana
- Thanasi Maria
- Thankachen M.
- Thirlwall Yvette
- Thirumaran Muthu
- Thomas A.
- Thomas A.
- Thomas B.
- Thomas E.
- Thomas H.
- Thomas Jacqueline
- Thomas M.
- Thomas R.
- Thomas V.
- Thomis L.
- Thompsom Maria
- Thompson Christopher
- Thompson R.
- Thompson Ryan C.
- Thomson Nicola
- Thornton D.
- Thornton L.
- Thorpe C.
- Thrasyvoulou Laura.
- Thrush Jessica
- Thwaites V.
- Thys M.
- Tibke Clare
- Tierney Carey
- Tilbey S.
- Tilney Emma
- Timlick E.
- Timmers Paul R.H.J.
- Ting L.
- Tiseo G.
- Tita R.
- Tivenan H.
- Tobin Martin D.
- Todd A.
- Todd Linda
- Tolson M.
- Tomas A.L.
- Tommasi A.
- Tonks L.
- Torky Mohamed S.
- Torrents D.
- Torvorapanit Pattama
- Tracy B.
- Trankiem Amy
- Tranter Helen
- Trembath R.C.
- Tridente Ascanio
- Trim F.
- Trivedi B.
- Trodd D.
- Trogstad L.I.S.
- Trotman Sallyanne
- Trotta T.
- Trower H.
- Truman Nick
- Trumper E.
- Tsao P.
- Tselios C.
- Tsinaslanidis George
- Tsuo K.
- Tucci A.
- Tuckey V.
- Tully Redmond
- Tumbarello M.
- Turki S.
- Turley P.
- Turnbull A.
- Turner Keri
- Turner Lynne
- Turner P.
- Turner Victoria
- Turner-Bone I.
- Turney S.
- Turtle Lance
- Tutton R.
- Twiss S.
- Tyl David
- Tyler A.
- Uitterlinden A.G.
- Underwood Slayton J.
- Vaghi M.
- Vaida M.
- Valente S.
- Valentine J.
- Valentino F.
- van Blokland I.
- van Heel D.A.
- van Koutrik L.
- Varghese M.
- Vecchia M.
- Vedage D.
- Veerapen Kumar
- Venkatesh Harish
- Venn Laura D.
- Venturelli S.
- Vergori A.
- Verlander M.
- Verma Anurag
- Verma S.S.
- Vertue M.
- Verula J.
- Verzuri A.
- Vigurs Charlie
- Villalonga J.M.
- Vincent Rachel
- Vincenti A.
- Virgilio Emma
- Vitart Veronique
- Vizcaychipi M.P.
- Vochin A.
- Voide C.
- von Frenckell C.
- von Hohenstaufen Kathrin Aprile
- Vonk J.M.
- Vulesevic B.
- Vuylsteke A.
- Wackett Tony
- Wadams B.
- Waddington N.
- Wagstaff Veronica
- Wain Louise V.
- Waite Alicia A.C.
- Wakefield Phillipa
- Wakinshaw F.
- Waldron J.
- Walker D.
- Walker R.
- Walker S.
- Walker Susan
- Wall Alanna
- Walsh Timothy
- Walters R.K.
- Walton Olivia
- Wang Bo
- Wang J.
- Wang Xueyang
- Wanying Zhu
- Ward G.
- Ward Luke
- Ward Mairi
- Warden Scott
- Warmerdam R.
- Warren D.
- Wassall H.
- Wasson C.
- Watkins Claire
- Watson E.
- Watson G.
- Watson J.
- Watters M.
- Waugh Victoria
- Weaver Jane
- Webster A.
- Webster D.
- Webster K.
- Wei Shuying
- Weiss S.T.
- Weldon C.H.
- Wells C.
- Welters Ingeborg D.
- Weston H.
- Whileman A.
- Whitbread J.
- White Deborah
- White Ian
- White K.
- White M.
- White N.
- White N.
- Whiteley Simon
- Whiteside J.
- Whittle H.
- Whitton Christopher
- Whyte Clare
- Wicks S.J.
- Wilby Elizabeth
- Wilcox L.
- Wilcox R.
- Wild H.
- Wild Laura
- Wiles M.
- Wilkins J.
- Wilkinson Ami
- Wilkinson B.
- Willer C.
- Williams A.
- Williams A.
- Williams A.
- Williams Alexander T.
- Williams D.
- Williams E.
- Williams F.
- Williams Gemma
- Williams H.
- Williams Karen
- Williams Marie
- Williams P.
- Williams S.
- Williams Toran
- Willis C.
- Willis Heather
- Wills M.
- Willson J.
- Wilson A.
- Wilson D.J.
- Wilson James F.
- Wilson Jean
- Winnard Sarah
- Winter-Goodwin B.
- Wolf-Roberts R.
- Wolford Brooke N.
- Wong Joanna
- Wood D.
- Wood Hannah-Louise
- Wood Suzanne
- Wood T.
- Woodford C.
- Woodruff M.
- Woods L.
- Woodyatt Wiesia
- Woolley A.E.
- Worner R.
- Worsley L.
- Wray G.
- Wren L.
- Wright D.
- Wright J.
- Wright M.
- Wrobel Nicola
- Wu Yang
- Wulandari R.
- Wyllie D.H.
- Wynter I.
- Xavier Kugan
- Xue X.
- Yadav A.
- Yang Jian
- Yassen Amr M.
- Yates Brian
- Ye C.
- Yun Nikki
- Zainy Tala
- Zak Anne
- Zaki Ahmed
- Zamikula J.
- Zanella I.
- Zborowski A.C.
- Zeberg Hugo
- Zechner Marie
- Zguro K.
- Zhang M.
- Zhao J.H.
- Zheng Chenqing
- Zhou W.
- Zitter L.
- Zlatopolsky Menachem
- Zongo Olivier
- Zucchi P.
- Zyndorf Marissa
- Zöllner S.
- Åsvold Bjørn Olav
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial
- Author
- Abrams Judith
- Adda Mireille
- Adderley Jane
- Adhikari Neill K. J.
- Adhikari Neill K. J.
- Aissaoui Nadia
- Alam Ahsan
- Albrett Jonathan
- Albright Robert C.
- Alcuaz Victoria
- Allam Hayat
- Altarelli Marco
- Amaral Andre
- Amsbaugh Amy
- Anderson Felicity
- Andreu Pascal
- Antunes Veronica
- Arbane Gill
- Argaud Laurent
- Arias Castro
- Asehnoune Karim
- Attwood Ben
- Auld Fiona
- Ayas Najib
- Aycinena Juan Carlos
- Azais Marie-Ange
- Bachler Mirjam
- Backhouse Felicity
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Bagshaw Sean M.
- Baharlo Behrad
- Bai Guoqiang
- Bai Jing
- Baig Nadia
- Baig Nadia
- Bailey Matthew
- Baker Nerilee
- Ball Ian M.
- Ball Jonathan
- Barbar Saber Davide
- Barbier François
- Barchard Jennifer
- Bass Frances
- Bates Samantha
- Baudry Thomas
- Beck James
- Beehre Nina
- Bellemare David
- Belley-Cote Emilie
- Bellmann Romuald
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benettaib Fatna
- Benoit Luc
- Benton Jane
- Benzekri Dalila
- Bergin Colin
- Bihari Shailesh
- Bihorac Azra
- Bird Sarah
- Bitker Laurent
- Board Jasmin
- Bociek Aneta
- Bohé Julien
- Boisrame-Helms Julie
- Boivin Annick
- Bojic Andja
- Bone Allison
- Boschert Catherine
- Bouisse Camille
- Boulain Thierry
- Boulet Éric
- Boumahni Dounia
- Bourchard Pierre-Alexandre
- Bowman Katie
- Bracke Stephanie
- Bradford Celia
- Brailsford Jane
- Brandtner Anna
- Bretagnol Anne
- Brickell Kathy
- Broadfield Emma
- Brodutch Shira
- Brooks Jenny
- Brown Gillian
- Brown Sherry
- Browne Troy
- Buehner Ulrike
- Buhr Heidi
- Burke Tara
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- Fletcher Jason
- Forbes Loretta
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- Forshaw Greg
- Foulkes Stephen
- Francoeur Charles Langis
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- French Craig
- Friedrich Jan
- Fries Dietmar
- Fu Lijuan
- Fu Yongjian
- Fusco Kelly
- Gallagher Martin P.
- Gallagher Martin P.
- Gangopadhyay Himangsu
- Gantner Dashiell
- Gao Lan
- Garg Amit
- Gattas David
- Gatward Jonathan
- Gaudry Stéphane
- Gaudry Stéphane
- George Aparna
- Georgescu Ilinca
- Gernez Coralie
- Ghamraoui Ali
- Ghate Taneera
- Ghosh Angaj
- Giannakouros Panagiota
- Gibson Neil
- Giebel Shelley
- Gilder Eileen
- Glybina Anna
- Gomes Brigette
- Gomez Raquel
- Goodson Jennifer
- Gordon Boyd J.
- Goulart Joyce McKenney
- Goulart Joyce McKenney
- Goundry Stephanie
- Grainger Lia
- Grangé Steven
- Grant Alice
- Grant Caroline
- Gray Geraldine
- Grenier Stéphanie
- Gresham Rebecca
- Grillot Nicolas
- Guerot Emmanuel
- Guery Aurore
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- Guitton Christophe
- Guo Dongchen
- Guo Litao
- Gurung Babita
- Gutierrez David
- Guy Zoe
- Haljan Gregory
- Hall Adam
- Hallion Jane
- Haltia Paivi
- Hambrook Geraldine
- Hammond Naomi
- Hamshere Alexandra
- Hang Lele
- Harasemiw Oksana
- Harkett Samanth
- Harkins Margaret
- Harmon John
- Harris Claire-Louise
- Harrop Clare
- Hartig Frank
- Harvey Dan
- Hashemighouchani Haleh
- Haslam Nicole
- Hasslacher Julia
- Hauschild Caroline
- Hazelton Tracy
- He Xiandi
- He Xiaona
- Heidegger Claudia
- Heinonen Jonna
- Henderson Seton
- Henderson Steven
- Hendry Deborah
- Hernandez Clara
- Hernu Romain
- Herridge Margaret S.
- Higson Vicki
- Hill Dianne
- Hill Helen
- Hindle Julia
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- Hirst Claire
- Hodder Jennifer
- Hodgson Luke E.
- Hopkins Philip
- Hoppu Sanna
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- Hou Guo
- Houghton James
- Howard Kate
- Howcroft Clare
- Howe Elizabeth
- Howlett Luisa
- Hu Chenghuan
- Hu Tingting
- Hu Xiaobo
- Huang Lili
- Huang Yingzi
- Hunt Anna
- Hunt Miranda
- Hunter Stephanie
- Hussain Nauman
- Hutch Debra
- Inkinen Outi
- Investigators STARRT-AKI
- Jackson Carolyn
- Jackson David
- Jagannathan Vijay
- Jalkanen Ville
- Jang Ryan
- Janin Pierre
- Ji Xiaojun
- Jim Kym
- Jin Xia
- Joannidis Michael
- Joannidis Michael
- Johnson Emily
- Johnston Andy
- Joseph Gipsy
- Judd Harriet
- Junge Andrea
- Järvisalo Mikko J.
- Kamel Toufik
- Kapoor Ritoo
- Karachi Tim
- Karlsson Sari
- Kashani Kianoush B.
- Kaufman Melissa
- Kaur Navjot
- Kavikondala Kanthi
- Kaye Callum
- Keet Owen
- Kentala Satu
- Kerr Deborah
- Khalid Imrana
- Ki Vincent
- Kiley Sean
- Kirkham Simon
- Kissling Sébastien
- Klein David
- Klein Sebastian
- Knight David
- Knott Cameron
- Koglberger Paul
- Kokotsis Nicos
- Kol Mark
- Koottayi Sathyajith
- Korhonen Anna-Maija
- Kruger Peter
- Kuitunen Anne
- Kummerlen Christine
- Kutsogiannis Demetrios J.
- Küllmar Mira
- Lacave Guillaume
- Lacherade Jean Claude
- Ladouceur Marilène
- Lafrance Jean-Philippe
- Lagarrigue Matthieu Henry-
- Lakatos Louis
- Lakhal Karim
- Lambert Bridget
- Lamontagne François
- Lamontagne François
- Lamontagne François
- Landais Mickael
- Landoni Giovanni
- Lapinsky Stephen
- Lappi Eliria
- Large Audrey
- Latimer-Bell Charlotte
- Latta Laura
- Laurie Gordon
- Lauzier François
- Lawrence Cassie
- Le Moal Charlène
- Leaver Susannah
- Lebert Christine
- LeBlanc Guillaume
- Lebrasseur Martine
- Lee Sandra
- Leivo Keijo
- Lellouche Francois
- Lembo Rosalba
- Lenga Ilan
- Lesona Eden
- Levoranta Markus
- Li Hao
- Li Jian
- Li Jianquan
- Li Jing
- Li Min
- Li Nan
- Li Rui
- Lian Yingtao
- Liangos Orfeas
- Licari Elisa
- Lim Rosario
- Lin Jin
- Lin Jincan
- Liu Airan
- Liu Cheng
- Liu Hongjuan
- Liu Jingfeng
- Liu Kathleen D.
- Liu Manli
- Liu Pei
- Liu Xingang
- Liu Yu
- Liu Zhongmin
- Liu Zhou
- Liu Zhuang
- Lizotte Patricia
- Lobaz Steve
- Lombardi Gaetano
- Long Dali
- Long Stephanie
- Lord Jenny
- Lowrey Julie
- Lu Kun
- Lu Liping
- Lyas Claretha
- Lynch Matthew
- Lynch Matthew
- Långsjö Jaakko
- Ma Hongye
- MacIntyre Erika
- Magder Sheldon
- Maguire Teena
- Maizel Julien
- Malila Kaisa
- Mallaird Samia Abed
- Mallet Maxime
- Manns Braden J.
- Manso Katarina
- Marceron Alina
- Marchalot Antoine
- Marchand Joannie
- Margalef Jordi
- Margarson Michael
- Marinoff Nicole
- Marios Clémence
- Marotti Martina
- Marque Sophie
- Martin Emma
- Martin-Lefevre Laurent
- Martino Frédéric
- Martins Laura
- Marzaroli Matteo
- Marzouk Mehdi
- Masi Paul
- Maslove David
- Mason Chris
- Mason Sophie
- Mason Tracy
- Masse Marie-Hélène
- Masters Kristy
- Matheson Elisha
- Mathonnet Armelle
- Mayaux Julien
- Mayette Michael
- Mazer David
- McArthur Colin
- McAuley Daniel F.
- McAuley Danny F.
- McCall Philip
- McClure Jason
- McConnochie Rachael
- McCoshen Lorena
- McCracken Phoebe
- McGain Forbes
- McGlone Philip
- McGloughlin Steve
- McGonigal Elizabeth
- McGuinness Shay
- McGuinness Shay
- McGuinness Shay P.
- McIntyre Lauralyn
- Mckay-Vucago Agnes
- McKerrow Elizabeth
- McLaughlan Derek
- Meehan Sharon
- Mehrtens Jan
- Mehta Navdeep
- Mehta Sangeeta
- Mei Huaxian
- Mei Jing
- Meng Zhaoli
- Merdji Hamid
- Meredith Megan
- Messika Jonathan
- Mew Louise
- Meyer Jason
- Meziani Ferhat
- Millen Tina
- Mitchell Wendy
- Mo Min
- Monnier Alexandra
- Monti Giacomo
- Montillier Philippe
- Moon Angela
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- Morawiec Elise
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- Morgan Matt
- Morgan Rebecca
- Morgan Stacey
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- Moser Max
- Mu Sijie
- Mulder John
- Muller Grégoire
- Muller Lucie
- Murray Lauren
- Murray Patrick T.
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- Naeem Syed
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- Nichol Alistair D.
- Nichol Alistair D.
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- Niven Daniel J.
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- Orford Neil
- Ortiz-Soriano Victor M.
- Ostermann Marlies
- Ostermann Marlies
- Ostermann Marlies
- Ovakim Daniel
- Ovsenek Athena
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- O’Mara AnnMarie
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- Palevsky Paul M.
- Pan Chun
- Pan Yu
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- Stelfox Henry T.
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- Tridente Ascanio
- Trusson Rémi
- Tung Ying
- Turgeon Alexis F.
- Törnblom Sanna
- Udy Andrew
- Vaara Suvi
- Vaara Suvi T.
- Vaara Suvi T.
- Vallance Shirley
- Vamplew Luke
- van Diepen Sean
- van Waegeningh Thomas
- Van Hoa Dang
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- Varila Simo
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- Velez Laura
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- Vladic Chelsey
- Wagner Martin
- Walczak Karolina
- Wald Ron
- Wald Ron
- Wald Ron
- Wallace Samantha
- Wang Amanda Y.
- Wang Chuanyao
- Wang Chunting
- Wang Cunzhen
- Wang Dongxin
- Wang Haibo
- Wang Haiman
- Wang Jane
- Wang Jinlong
- Wang Kaiwu
- Wang Peng
- Wang Qizhi
- Wang Quihui
- Wang Xue
- Wang Yifeng
- Ward Geraldine
- Watpool Irene
- Watson Hayley
- Waugh Victoria
- Wax Randy
- Weir Matthew
- Weir Matthew A.
- Welsh Deborah
- Welters Ingeborg
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- Wetzig Krista
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- Whitehead Christina
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- Whitlock Richard P.
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- Williams Erin
- Williams Karen
- Willox Fiona
- Wise Matthew
- Wittig Monika
- Wolverson Adam
- Wong Helen
- Wood Gordon
- Woolett Melissa
- Wootten Anna
- Wren Lynn
- Wu Changde
- Wu Jing
- Wun James
- Wyncoll Duncan
- Xu Hao
- Xu Song
- Yan Jie
- Yan Jinqi
- Yang Enyu
- Yang Jianxu
- Yang Juan
- Yang Yang
- Yang Yi
- Yang Ziqi
- Yao Han
- Yao Lan
- Yarad Elizabeth
- Ye Baning
- Yehia Aihem
- Young Helen
- Young Meredith
- Young Paul
- Youngs Nora
- Yu Zhui
- Zahirieh Alireza
- Zampieri Fernando G.
- Zangrillo Alberto
- Zarbock Alexander
- Zeng Qinjing
- Zhang Jichen
- Zhang Lei
- Zhang Meng
- Zhang Minwei
- Zhang Songsong
- Zhao Dan
- Zhao Mengya
- Zhao Shibing
- Zhao Shuangping
- Zhi Deyuan
- Zhou Qi
- Zhou Xiao
- Zhuang Haizhou
- Zotter Klemens
- Zuber Benjamin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Background
Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared two strategies of KRT initiation (accelerated versus standard) in critically ill patients with acute kidney injury and found neutral results for 90-day all-cause mortality. Probabilistic exploration of the trial endpoints may enable greater understanding of the trial findings. We aimed to perform a reanalysis using a Bayesian framework.
Methods
We performed a secondary analysis of all 2927 patients randomized in multi-national STARRT-AKI trial, performed at 168 centers in 15 countries. The primary endpoint, 90-day all-cause mortality, was evaluated using hierarchical Bayesian logistic regression. A spectrum of priors includes optimistic, neutral, and pessimistic priors, along with priors informed from earlier clinical trials. Secondary endpoints (KRT-free days and hospital-free days) were assessed using zero–one inflated beta regression.
Results
The posterior probability of benefit comparing an accelerated versus a standard KRT initiation strategy for the primary endpoint suggested no important difference, regardless of the prior used (absolute difference of 0.13% [95% credible interval [CrI] − 3.30%; 3.40%], − 0.39% [95% CrI − 3.46%; 3.00%], and 0.64% [95% CrI − 2.53%; 3.88%] for neutral, optimistic, and pessimistic priors, respectively). There was a very low probability that the effect size was equal or larger than a consensus-defined minimal clinically important difference. Patients allocated to the accelerated strategy had a lower number of KRT-free days (median absolute difference of − 3.55 days [95% CrI − 6.38; − 0.48]), with a probability that the accelerated strategy was associated with more KRT-free days of 0.008. Hospital-free days were similar between strategies, with the accelerated strategy having a median absolute difference of 0.48 more hospital-free days (95% CrI − 1.87; 2.72) compared with the standard strategy and the probability that the accelerated strategy had more hospital-free days was 0.66.
Conclusions
In a Bayesian reanalysis of the STARRT-AKI trial, we found very low probability that an accelerated strategy has clinically important benefits compared with the standard strategy. Patients receiving the accelerated strategy probably have fewer days alive and KRT-free. These findings do not support the adoption of an accelerated strategy of KRT initiation
Regional Practice Variation and Outcomes in the Standard Versus Accelerated Initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) Trial: A Post Hoc Secondary Analysis.
- Author
- Abed Mallaird Samia
- Abrams Judith
- Adda Mireille
- Adderley Jane
- Adhikari Neill KJ
- Adhikari Neill KJ
- Adhikari Neill KJ
- Aissaoui Nadia
- Alam Ahsan
- Albrett Jonathan
- Albright Robert C
- Alcuaz Victoria
- Allam Hayat
- Altarelli Marco
- Amaral Andre
- Amsbaugh Amy
- Amélie Ordon Marie
- Anderson Felicity
- Andreu Pascal
- Antunes Veronica
- Arbane Gill
- Argaud Laurent
- Arias Castro
- Asehnoune Karim
- Attwood Ben
- Auld Fiona
- Ayas Najib
- Azais Marie-Ange
- Bachler Mirjam
- Backhouse Felicity
- Bagshaw Sean M
- Bagshaw Sean M
- Bagshaw Sean M
- Bagshaw Sean M
- Baharlo Behrad
- Bai Guoqiang
- Bai Jing
- Baig Nadia
- Baig Nadia
- Bailey Matthew
- Baker Nerilee
- Ball Ian M
- Ball Jonathan
- Barbar Davide
- Barbier François
- Barchard Jennifer
- Bass Frances
- Bates Samantha
- Baudry Thomas
- Beck James
- Beehre Nina
- Bellemare David
- Belley-Cote Emilie
- Bellmann Romuald
- Bellomo Rinaldo
- Bellomo Rinaldo
- Bellomo Rinaldo
- Benettaib Fatna
- Benoit Luc
- Benton Jane
- Benzekri Dalila
- Bergin Colin
- Bihari Shailesh
- Bihorac Azra
- Bird Sarah
- Bitker Laurent
- Board Jasmin
- Bociek Aneta
- Bohé Julien
- Boisrame-Helms Julie
- Boivin Annick
- Bojic Andja
- Bone Allison
- Boschert Catherine
- Bouisse Camille
- Boulain Thierry
- Boulet Éric
- Boumahni Dounia
- Bourchard Pierre-Alexandre
- Bowman Katie
- Bracke Stephanie
- Bradford Celia
- Brailsford Jane
- Brandtner Anna
- Bretagnol Anne
- Brickell Kathy
- Broadfield Emma
- Brodutch Shira
- Brooks Jenny
- Brown Gillian
- Brown Sherry
- Browne Troy
- Buehner Ulrike
- Buhr Heidi
- Burke Tara
- Burns Karen
- Buscher Hergen
- Butler Magdalena
- Butler Susie
- Cahill Hazel
- Cailhier Jean-François
- Callender Owen
- Campbell Eileen
- Campbell Troy
- Campbell Victoria
- Campisi Josie
- Camporota Luigi
- Campos Sara
- Canet Emmanuel
- Cantien Marie
- Carbonnaeu Élaine
- Carles Michel
- Carlos Aycinena Juan
- Carney Dominic
- Carney Gayle
- Carpentier Dorothée
- Carrera Ron
- Carrier François-Martin
- Carson Joshua
- Carter Joseph
- Carungcong Jaime
- Carvelli Paula
- Castro Delgado Carlos
- Cegarra Santiago
- Cennamo Armando
- Chadbourn Indra
- Chadwick Lesley
- Chan Peter
- Chee Nigel
- Chen Man
- Chen Yan
- Chen Zhenzhen
- Chenaf Samir
- Cheung Winston
- Chevrel Guillaume
- Chiella Bianca
- Chimunda Tim
- Christophe Callahan Jean
- Chudeau Nicolas
- Cinotti Raphaël
- Cirone Robert
- Clarey Emma
- Clark Amy
- Clark Edward
- Clark Michele
- Clarke France
- Claude Lacherade Jean
- Cleophax Cedric
- Clere-Jehl Raphael
- Cloutier Eve
- Cohen Yves
- Cole Jade
- Cole Louise
- Coles Jennifer
- Colin Gwenhaël
- Collins Amy
- Combes Alain
- Commeureuc Morgane
- Condin Christopher
- Conner Louise
- Cooper Lauren
- Corcoran Eleanor
- Costa Patricia
- Costerousse Olivier
- Coupez Elisabeth
- Cour Martin
- Cowdrey Keri-Anne
- Creary Thais
- Crosby Laura
- Cross Rosalba
- Cunningham Mishell
- Cupka Julie
- D'Aragon Frédérick
- Dang Van Hoa
- Daniels Alison
- Dargent Auguste
- De Crop Luc
- De La Salle Sylvie
- De Prost Nicolas
- De Watteville Aude
- Decalvele Maxens
- Dechanet Aline
- Dekeyser Thibault
- Delabranche Xavier
- Delaney Anthony
- Delecolle Lucie
- Delisle-Thibault Charles
- Demeure Dominique
- Demiri Suela
- Demoule Alexandre
- Deng Fuxing
- Derrien Benoit
- Despy Liesl
- Devereaux Kelson
- Di Nella Michelle
- Didier Thevenin Lens
- Diehl Jean-Luc
- Diel Naomi
- Dignam Gemma
- Dilawershah Maria
- Ding Lili
- Ding Ruiqi
- Ditlbacher Adelheid
- Dodek Peter
- Dominy Clive
- Dong Lei
- Dong Xin
- Dooley Natalie
- Doran Peter
- Dorfman Robert
- Dos Santos Sandra
- Dres Martin
- Dreyfuss Didier
- Dreyfuss Didier
- Dreyfuss Didier
- Drover John
- Du Bin
- Du Bin
- Duan Meili
- Dubos René
- Duffy Jane
- Duffy Karina
- Dufour Nicolas
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- Eastwood Glenn M
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- Mayaux Julien
- Mayette Michael
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- McArthur Colin
- McAuley Daniel F
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- Wald Ron
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- Ward Geraldine
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- Woolett Melissa
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- Wu Jing
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- Wyncoll Duncan
- Xu Hao
- Xu Song
- Yan Jie
- Yan Jinqi
- Yang Enyu
- Yang Jianxu
- Yang Juan
- Yang Yang
- Yang Yi
- Yang Ziqi
- Yao Han
- Yao Lan
- Yarad Elizabeth
- Ye Baning
- Yehia Aihem
- Young Helen
- Young Meredith
- Young Paul
- Youngs Nora
- Yu Zhui
- Zahirieh Alireza
- Zangrillo Alberto
- Zarbock Alexander
- Zeng Qinjing
- Zhang Jichen
- Zhang Lei
- Zhang Meng
- Zhang Minwei
- Zhang Songsong
- Zhao Dan
- Zhao Mengya
- Zhao Shibing
- Zhao Shuangping
- Zhi Deyuan
- Zhou Qi
- Zhou Xiao
- Zhuang Haizhou
- Zotter Klemens
- Zuber Benjamin
- Publication venue
- Ovid Technologies (Wolters Kluwer Health)
- Publication date
- 01/02/2024
- Field of study
ObjectivesAmong patients with severe acute kidney injury (AKI) admitted to the ICU in high-income countries, regional practice variations for fluid balance (FB) management, timing, and choice of renal replacement therapy (RRT) modality may be significant.DesignSecondary post hoc analysis of the STandard vs. Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial (ClinicalTrials.gov number NCT02568722).SettingOne hundred-fifty-three ICUs in 13 countries.PatientsAltogether 2693 critically ill patients with AKI, of whom 994 were North American, 1143 European, and 556 from Australia and New Zealand (ANZ).InterventionsNone.Measurements and main resultsTotal mean FB to a maximum of 14 days was +7199 mL in North America, +5641 mL in Europe, and +2211 mL in ANZ (p p p p p p p p = 0.007).ConclusionsAmong STARRT-AKI trial centers, significant regional practice variation exists regarding FB, timing of initiation of RRT, and initial use of continuous RRT. After adjustment, such practice variation was associated with lower ICU and hospital stay and 90-day mortality among ANZ patients compared with other regions