101 research outputs found
Single-Dose Therapy for Oral Candidiasis with Fluconazole in HIV-Infected Adults: A Pilot Study
Single-Dose Therapy for Oral Candidiasis with Fluconazole in HIV-Infected Adults: A Pilot Study
Catchment drainage network scaling laws found experimentally in overland flow morphologies
The scaling relation between the drainage area and stream length (Hack's law), along with exceedance probabilities of drainage area, discharge, and upstream flow network length, is well known for channelized fluvial regions. We report here on a laboratory experiment on an eroding unconsolidated sediment for which no channeling occurred. Laser scanning was used to capture the morphological evolution of the sediment. High-intensity, spatially nonuniform rainfall ensured that the morphology changed substantially over the 16-hr experiment. Based on the surface scans and precipitation distribution, overland flow was estimated with the D8 algorithm, which outputs a flow network that was analyzed statistically. The above-mentioned scaling and exceedance probability relationships for this overland flow network are the same as those found for large-scale catchments and for laboratory experiments with observable channels. In addition, the scaling laws were temporally invariant, even though the network dynamically changed over the course of experiment
Impact of transient groundwater storage on the discharge of Himalayan rivers
International audienceIn the course of the transfer of precipitation into rivers, water is temporarily stored in reservoirs with different residence times such as soils, groundwater, snow and glaciers. In the central Himalaya, the water budget is thought to be primarily controlled by monsoon rainfall, snow and glacier melt, and secondarily by evapotranspiration. An additional contribution from deep groundwater has been deduced from the chemistry of Himalayan rivers, but its importance in the annual water budget remains to be evaluated. Here we analyse records of daily precipitation and discharge within twelve catchments in Nepal over about 30 years. We observe annual hysteresis loops--that is, a time lag between precipitation and discharge--in both glaciated and unglaciated catchments and independent of the geological setting. We infer that water is stored temporarily in a reservoir with characteristic response time of about 45 days, suggesting a diffusivity typical of fractured basement aquifers. We estimate this transient storage capacity at about 28km3 for the three main Nepal catchments; snow and glacier melt contribute around 14km3yr-1, about 10% of the annual river discharge. We conclude that groundwater storage in a fractured basement influences significantly the Himalayan river discharge cycle
Characterization of Serum Proteins Associated with IL28B Genotype among Patients with Chronic Hepatitis C
Introduction: Polymorphisms near the IL28B gene (e.g. rs12979860) encoding interferon lambda 3 have recently been associated with both spontaneous clearance and treatment response to pegIFN/RBV in chronic hepatitis C (CHC) patients. The molecular consequences of this genetic variation are unknown. To gain further insight into IL28B function we assessed the association of rs12979860 with expression of protein quantitative traits (pQTL analysis) generated using open-platform proteomics in serum from patients
High elevation of low-relief surfaces in mountain belts: does it equate to post-orogenic uplift?
International audienc
Géodynamique andine : résumés étendus = Andean geodynamics : extended abstracts = Geodinamica andina : resumenes ampliados
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