190,819 research outputs found
Interest communities and flow roles in directed networks: the Twitter network of the UK riots
Directionality is a crucial ingredient in many complex networks in which
information, energy or influence are transmitted. In such directed networks,
analysing flows (and not only the strength of connections) is crucial to reveal
important features of the network that might go undetected if the orientation
of connections is ignored. We showcase here a flow-based approach for community
detection in networks through the study of the network of the most influential
Twitter users during the 2011 riots in England. Firstly, we use directed Markov
Stability to extract descriptions of the network at different levels of
coarseness in terms of interest communities, i.e., groups of nodes within which
flows of information are contained and reinforced. Such interest communities
reveal user groupings according to location, profession, employer, and topic.
The study of flows also allows us to generate an interest distance, which
affords a personalised view of the attention in the network as viewed from the
vantage point of any given user. Secondly, we analyse the profiles of incoming
and outgoing long-range flows with a combined approach of role-based similarity
and the novel relaxed minimum spanning tree algorithm to reveal that the users
in the network can be classified into five roles. These flow roles go beyond
the standard leader/follower dichotomy and differ from classifications based on
regular/structural equivalence. We then show that the interest communities fall
into distinct informational organigrams characterised by a different mix of
user roles reflecting the quality of dialogue within them. Our generic
framework can be used to provide insight into how flows are generated,
distributed, preserved and consumed in directed networks.Comment: 32 pages, 14 figures. Supplementary Spreadsheet available from:
http://www2.imperial.ac.uk/~mbegueri/Docs/riotsCommunities.zip or
http://rsif.royalsocietypublishing.org/content/11/101/20140940/suppl/DC
Random walks on mutual microRNA-target gene interaction network improve the prediction of disease-associated microRNAs
Background: MicroRNAs (miRNAs) have been shown to play an important role in pathological initiation, progression and maintenance. Because identification in the laboratory of disease-related miRNAs is not straightforward, numerous network-based methods have been developed to predict novel miRNAs in silico. Homogeneous networks (in which every node is a miRNA) based on the targets shared between miRNAs have been widely used to predict their role in disease phenotypes. Although such homogeneous networks can predict potential disease-associated miRNAs, they do not consider the roles of the target genes of the miRNAs. Here, we introduce a novel method based on a heterogeneous network that not only considers miRNAs but also the corresponding target genes in the network model. Results: Instead of constructing homogeneous miRNA networks, we built heterogeneous miRNA networks consisting of both miRNAs and their target genes, using databases of known miRNA-target gene interactions. In addition, as recent studies demonstrated reciprocal regulatory relations between miRNAs and their target genes, we considered these heterogeneous miRNA networks to be undirected, assuming mutual miRNA-target interactions. Next, we introduced a novel method (RWRMTN) operating on these mutual heterogeneous miRNA networks to rank candidate disease-related miRNAs using a random walk with restart (RWR) based algorithm. Using both known disease-associated miRNAs and their target genes as seed nodes, the method can identify additional miRNAs involved in the disease phenotype. Experiments indicated that RWRMTN outperformed two existing state-of-the-art methods: RWRMDA, a network-based method that also uses a RWR on homogeneous (rather than heterogeneous) miRNA networks, and RLSMDA, a machine learning-based method. Interestingly, we could relate this performance gain to the emergence of "disease modules" in the heterogeneous miRNA networks used as input for the algorithm. Moreover, we could demonstrate that RWRMTN is stable, performing well when using both experimentally validated and predicted miRNA-target gene interaction data for network construction. Finally, using RWRMTN, we identified 76 novel miRNAs associated with 23 disease phenotypes which were present in a recent database of known disease-miRNA associations. Conclusions: Summarizing, using random walks on mutual miRNA-target networks improves the prediction of novel disease-associated miRNAs because of the existence of "disease modules" in these networks
Flow-Based Network Analysis of the Caenorhabditis elegans Connectome
We exploit flow propagation on the directed neuronal network of the nematode C. elegans to reveal dynamically relevant features of its connectome. We find flow-based groupings of neurons at different levels of granularity, which we relate to functional and anatomical constituents of its nervous system. A systematic in silico evaluation of the full set of single and double neuron ablations is used to identify deletions that induce the most severe disruptions of the multi-resolution flow structure. Such ablations are linked to functionally relevant neurons, and suggest potential candidates for further in vivo investigation. In addition, we use the directional patterns of incoming and outgoing network flows at all scales to identify flow profiles for the neurons in the connectome, without pre-imposing a priori categories. The four flow roles identified are linked to signal propagation motivated by biological input-response scenarios
Link Prediction in Complex Networks: A Survey
Link prediction in complex networks has attracted increasing attention from
both physical and computer science communities. The algorithms can be used to
extract missing information, identify spurious interactions, evaluate network
evolving mechanisms, and so on. This article summaries recent progress about
link prediction algorithms, emphasizing on the contributions from physical
perspectives and approaches, such as the random-walk-based methods and the
maximum likelihood methods. We also introduce three typical applications:
reconstruction of networks, evaluation of network evolving mechanism and
classification of partially labelled networks. Finally, we introduce some
applications and outline future challenges of link prediction algorithms.Comment: 44 pages, 5 figure
A similarity-based community detection method with multiple prototype representation
Communities are of great importance for understanding graph structures in
social networks. Some existing community detection algorithms use a single
prototype to represent each group. In real applications, this may not
adequately model the different types of communities and hence limits the
clustering performance on social networks. To address this problem, a
Similarity-based Multi-Prototype (SMP) community detection approach is proposed
in this paper. In SMP, vertices in each community carry various weights to
describe their degree of representativeness. This mechanism enables each
community to be represented by more than one node. The centrality of nodes is
used to calculate prototype weights, while similarity is utilized to guide us
to partitioning the graph. Experimental results on computer generated and
real-world networks clearly show that SMP performs well for detecting
communities. Moreover, the method could provide richer information for the
inner structure of the detected communities with the help of prototype weights
compared with the existing community detection models
Studying and Modeling the Connection between People's Preferences and Content Sharing
People regularly share items using online social media. However, people's
decisions around sharing---who shares what to whom and why---are not well
understood. We present a user study involving 87 pairs of Facebook users to
understand how people make their sharing decisions. We find that even when
sharing to a specific individual, people's own preference for an item
(individuation) dominates over the recipient's preferences (altruism). People's
open-ended responses about how they share, however, indicate that they do try
to personalize shares based on the recipient. To explain these contrasting
results, we propose a novel process model of sharing that takes into account
people's preferences and the salience of an item. We also present encouraging
results for a sharing prediction model that incorporates both the senders' and
the recipients' preferences. These results suggest improvements to both
algorithms that support sharing in social media and to information diffusion
models.Comment: CSCW 201
Topology comparison of Twitter diffusion networks effectively reveals misleading information
In recent years, malicious information had an explosive growth in social
media, with serious social and political backlashes. Recent important studies,
featuring large-scale analyses, have produced deeper knowledge about this
phenomenon, showing that misleading information spreads faster, deeper and more
broadly than factual information on social media, where echo chambers,
algorithmic and human biases play an important role in diffusion networks.
Following these directions, we explore the possibility of classifying news
articles circulating on social media based exclusively on a topological
analysis of their diffusion networks. To this aim we collected a large dataset
of diffusion networks on Twitter pertaining to news articles published on two
distinct classes of sources, namely outlets that convey mainstream, reliable
and objective information and those that fabricate and disseminate various
kinds of misleading articles, including false news intended to harm, satire
intended to make people laugh, click-bait news that may be entirely factual or
rumors that are unproven. We carried out an extensive comparison of these
networks using several alignment-free approaches including basic network
properties, centrality measures distributions, and network distances. We
accordingly evaluated to what extent these techniques allow to discriminate
between the networks associated to the aforementioned news domains. Our results
highlight that the communities of users spreading mainstream news, compared to
those sharing misleading news, tend to shape diffusion networks with subtle yet
systematic differences which might be effectively employed to identify
misleading and harmful information.Comment: A revised new version is available on Scientific Report
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