Terahertz-based system for dehydration analysis of hydrogel contact lenses

The use of terahertz-based techniques has grown very fast since they are capable of performingevaluations at molecular level, being very suitable for the analysis of biological samples and bioma-terials such as those for contact lenses. These biomaterials are continuously evolving to enhancethe lens wearer’s comfort by improving their hydration state and surface wettability. Therefore, thisstudy examines a novel terahertz system for the assessment of the temporary in vitro dehydrationof hydrogel contact lenses, which provides a new index to assess their state of hydration. Severalconventional and silicone hydrogel contact lenses and lens care solutions were analysed. Traditionalmethods such as the gravimetric determination of water content and the measurement of the staticcontact angle were also carried out for the validation of the developed system. The dehydrationrate measurements of contact lenses obtained with the proposed system correlated with the valuesprovided by traditional methods. As a whole, conventional hydrogel contact lenses exhibited thelowest values for dehydration rate. The tests conducted on various solutions showed a correlationbetween the wetting action of the solution and the dehydration rate of the contact lens material.Peer ReviewedPostprint (published version

Stretchable electronic platform for soft and smart contact lens applications

A stretchable platform with spherical-shaped electronics based on thermo- plastic polyurethane (TPU) is introduced for soft smart contact lenses. The low glass transition temperature of TPU, its relatively low hardness, and its proven biocompatibility (i.e., protection of exterior body wounds) fulfill the essential requirements for eye wearable devices. These requirements include optical transparency, conformal fitting, and flexibility comparable with soft contact lenses (e.g., hydrogel-based). Moreover, the viscoelastic nature of TPU allows planar structures to be thermoformed into spherical caps with a well-defined curvature (i.e., eye’s curvature at the cornea: 9 mm). Numerical modeling and experimental validation enable fine-tuning of the thermo - forming parameters and the optimization of strain-release patterns. Such tight control is proven necessary to achieve oxygen permeable, thin, nonde- velopable, and wrinkle-free contact lenses with integrated electronics (silicon die, radio-frequency antenna, and stretchable thin-film interconnections). This work paves the way toward fully autonomous smart contact lenses potentially for vision correction or sensing applications, among others

Printing of wirelessly rechargeable solid-state supercapacitors for soft, smart contact lenses with continuous operations

Recent advances in smart contact lenses are essential to the realization of medical applications and vision imaging for augmented reality through wireless communication systems. However, previous research on smart contact lenses has been driven by a wired system or wireless power transfer with temporal and spatial restrictions, which can limit their continuous use and require energy storage devices. Also, the rigidity, heat, and large sizes of conventional batteries are not suitable for the soft, smart contact lens. Here, we describe a human pilot trial of a soft, smart contact lens with a wirelessly rechargeable, solid-state supercapacitor for continuous operation. After printing the supercapacitor, all device components (antenna, rectifier, and light-emitting diode) are fully integrated with stretchable structures for this soft lens without obstructing vision. The good reliability against thermal and electromagnetic radiations and the results of the in vivo tests provide the substantial promise of future smart contact lenses

Patients’ attitudes and beliefs to presbyopia and its correction

Objective Presbyopia is the gradual inability to focus near objects with age. This study explores patients’ attitudes and beliefs towards presbyopia including preferred modes of near refractive correction. Methods In the United Kingdom, twenty-four volunteers completed an online questionnaire and attended a structured, recorded focus group. Participants’ age ranged between 36 and 48 years, representing a pre-presbyopic and a presbyopic population. Attitudes and beliefs about presbyopia, its significance, and opinions about current refractive correction including multifocal contact lenses were transcribed and coded using content analysis for overarching themes and patterns. Results Six participants (25%) were already wearing a near visual correction while 18 (75%) were not. Five key primary themes with clear inter-participant similarities were identified as ‘age-related’ (75%), ‘acceptance’ (50%), clear lack of ‘familiarity with the word presbyopia’ (65%), a mixed/ reluctant attitude ‘towards (multifocal) contact lenses’ (62.5%), and ‘comfort and convenience’ of a presbyopic correction (79%) whereby cost is of less importance. Conclusion The need for a reading correction was perceived as a sign of age. Spectacles were the most preferred mode of near vision correction, while comfort and convenience were seen as more important than cost. Patient education about presbyopia is lacking. Multifocal contact lenses are not necessarily the preferred visual correction even if the patient already wears contact lenses for distance

Incidental discovery of circle contact lens by MRI: you can’t scan my poker face, circle contact lens as a potential MRI hazard

BACKGROUND: Circle contact lenses, also known as color contact lenses and big eye contact lenses, are a type of cosmetic contact lens. It is not generally known that a circle contact lens usually contains iron oxide and other metals, which means their use during magnetic resonance imaging (MRI) is a potential hazard. CASE PRESENTATION: We present a rare case of incidental discovery of circle contact lenses by MRI and MRI images of circle lenses in vitro. CONCLUSIONS: Circle contact lenses usually contain iron oxide, which is a known source of susceptibility artifact on MRI. Not only radiologists and radiographers but also referring physicians should be familiar with the imaging findings and potential risk of scanning circle contact lenses by MRI

Contact Lens Visual Rehabilitation in Keratoconus and Corneal Keratoplasty

Keratoconus is the most common corneal distrophy. It's a noninflammatory progressive thinning process that leads to conical ectasia of the cornea, causing high myopia and astigmatism. Many treatment choices include spectacle correction and contact lens wear, collagen cross linking, intracorneal ring segments implantation and finally keratoplasty. Contact lenses are commonly used to reduce astigmatism and increase vision. There are various types of lenses are available. We reviewed soft contact lenses, rigid gas permeable contact lenses, piggyback contact lenses, hybrid contact lenses and scleral-semiscleral contact lenses in keratoconus management. The surgical option is keratoplasty, but even after sutur removal, high astigmatism may stil exists. Therefore, contact lens is an adequate treatment option to correct astigmatism after keratoplasty

Use of Scleral Lenses in the Visual Rehabilitation of Keratoconus: A Case Series

Introduction: Scleral lenses also known as scleral contact lenses are rigid gas permeable contact lenses that rest entirely on the sclera without touching the cornea. This unique feature of scleral lenses makes it ideal in the management of complex corneal and ocular surface irregularity. Purpose: To report the indications, use and fiting of Europa scleral lenses for the visual rehabilitation of two patients with Keratoconus in a specialty contact lens practice in Abuja, Nigeria. Case reports: We report the cases of two female patients of Nigerian descent diagnosed with Keratoconus who were managed previously with other modalities of contact lenses but presented with unsatisfactory vision and discomfort with their habitual correction. The patients experienced vision fluctuation and discomfort with their lenses. They were diagnosed with contact lens induced papillary conjunctivitis (Case1) and contact lens induced ocular surface disease (Case2) and uncorrected irregular astigmtism secondary to keratoconus (both cases). Following the management of the ocular surface disease both patients were fit into Europa scleral contact lenses which provided excellent vision and comfort to the patients. Conclusion: Scleral lenses are indicated in the management of complex corneal and ocular surface irregularities. These lenses vault the cornea and provide crisp vision expected of a rigid contact lens as well as comfort comparable to a soti lens.Keywords: Scleral contact lenses, Keratoconus, rigid gas permeable contact lenses, Ocular Surface disease

Nonsurgical Procedures for Keratoconus Management

Objectives. To describe the past 20 years’ correction modalities for keratoconus and their visual outcomes and possible complications. Methods. A review of the published literature related to the visual outcomes and possible complications in the context of keratoconus management using nonsurgical procedures for the last 20 years (glasses and contact lenses) was performed. Original articles that reported the outcome of any correction modalities of keratoconus management were reviewed. Results. The most nonsurgical procedure used on keratoconus management is the contact lens fitting. Soft contact lenses and soft toric contact lenses, rigid gas-permeable contact lenses, piggyback contact lens system, hybrid contact lenses, and scleral and corneoscleral contact lenses form the contemporary range of available lens types for keratoconus management with contact lenses. All of them try to restore the vision, improve the quality of life, and delay surgical procedures in patients with this disease. Complications are derived from the intolerance of using contact lens, and the use of each depends on keratoconus severity. Conclusions. In the context of nonsurgical procedures, the use of contact lenses for the management of keratoconic patients represents a good alternative to restore vision and improve the quality of live in this population

The impact of silicone hydrogel contact lenses on the measurement of intraocular pressure using non-contact tonometry

© 2017, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved. Background/Aim. Measurement of intraocular pressure (IOP) over therapeutic silicone hydrogel soft contact lenses by a non-contact method of tonometry could be applied in opthalmologic practice but the results obtained are still controversial. The aim of this study was to evaluate the effect of spherically designed silicone hydrogel soft contact lenses and their power on values of IOP measured by using a non-contact tonometry method. Methods. We measured IOP with and without spherical silicone hydrogel soft contact lenses on 143 eyes of 80 subjects who did not have any ocular or systemic diseases. Results. The Wilcoxon statistical analysis test for ranking average values of IOP measured on 143 eyes over a spherical silicone hydrogel soft contact lenses showed significantly higher values compared to those measured with no contact lenses (15.81 ± 3.46 mm Hg vs 14.54 ± 3.19 mm Hg; respectively; Z = -5.224, p = 0.001). Refractive power analysis of the contact lenses of -9.00D to +6.00 D showed a significant difference of IOP in the range from 0.00D to -6.00D. Conclusion. Non-contact tonometry is not an accurate method of IOP measuring over spherical silicone hydrogel soft contact lenses which belong to therapeutic contact lenses

The effect of lens wear on refractive index of conventional hydrogel and silicone-hydrogel contact lenses: a comparative study

Purpose: The purpose of this work was to evaluate the ability of four silicone-hydrogel contact lenses (galyfilcon A, balafilcon A, lotrafilcon A and lotrafilcon B) to retain their equilibrium water content before and after wear, through measurements of refractive index and compare with that of a conventional disposable hydrogel contact lens (etafilcon A). Methods: The refractive indices of 115 contact lenses were measured using an automated refractometer (CLR 12-70, Index Instruments, Cambridge, U.K.) before and after a schedule of daily wear by 58 patients for 30 days in the case of silicone-hydrogel lenses and 15 days for the conventional contact lenses. Results: In the silicone-hydrogel contact lenses the changes on the refractive indices were not statistically significant, however after being worn the refractive index of the conventional etalfilcon A hydrogel contact lens increased significantly ( p < 0.001). Conclusion: The results presented here show that after being worn the silicone-hydrogel contact lens, show more capacity to retain or to reach their initial equilibrium water content than conventional hydrogel contact lenses. This suggests that the silicone-hydrogel contact lenses are less susceptible to spoilation over time maintaining its biocompatibility and contributing to the clinical success of lens performance.Vision and Johnson & Johnson.Bausch & Lom