138 research outputs found

    Maximising Consent: Operationalising Reciprocity in Secession Referenda

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    A constitutional referendum on secession from Indonesia was held in East Timor in 1999, with a pro-independence vote triggering widespread violence by the Indonesian army and pro-union militia. Montenegro underwent a similar process in 2006, also opting for independence but with much smoother results. This article will suggest that the deliberative democratic principle of reciprocity can help deliver referendum law based on justifications that can be accepted by all parties concerned. In particular, it proposes that reciprocity can be operationalised in referendum law if the participants in the negotiations that formulate the laws accept fair terms of social cooperation (FTSCs) and resolve disagreements using economy of moral disagreement (EMD). Respectively, these mean parties to negotiations should be willing to justify their position in mutually acceptable terms and if consensus is impossible, agreements should minimise their rejection of other parties’ views. This argument will be made using the negotiations that created East Timor and Montenegro’s referendum laws as case studies

    Transitions in climate and energy discourse between Hurricanes Katrina and Sandy

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    Although climate change and energy are intricately linked, their explicit connection is not always prominent in public discourse and the media. Disruptive extreme weather events, including hurricanes, focus public attention in new and different ways offering a unique window of opportunity to analyze how a focusing event influences public discourse. Media coverage of extreme weather events simultaneously shapes and reflects public discourse on climate issues. Here, we analyze climate and energy newspaper coverage of Hurricanes Katrina (2005) and Sandy (2012) using topic models, mathematical techniques used to discover abstract topics within a set of documents. Our results demonstrate that post-Katrina media coverage does not contain a climate change topic, and the energy topic is limited to discussion of energy prices, markets, and the economy with almost no explicit linkages made between energy and climate change. In contrast, post-Sandy media coverage does contain a prominent climate change topic, a distinct energy topic, as well as integrated representation of climate change and energy, indicating a shift in climate and energy reporting between Hurricane Katrina and Hurricane Sandy

    Optimal search strategies for hidden targets

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    What is the fastest way of finding a randomly hidden target? This question of general relevance is of vital importance for foraging animals. Experimental observations reveal that the search behaviour of foragers is generally intermittent: active search phases randomly alternate with phases of fast ballistic motion. In this letter, we study the efficiency of this type of two states search strategies, by calculating analytically the mean first passage time at the target. We model the perception mecanism involved in the active search phase by a diffusive process. In this framework, we show that the search strategy is optimal when the average duration of "motion phases" varies like the power either 3/5 or 2/3 of the average duration of "search phases", depending on the regime. This scaling accounts for experimental data over a wide range of species, which suggests that the kinetics of search trajectories is a determining factor optimized by foragers and that the perception activity is adequately described by a diffusion process.Comment: 4 pages, 5 figures. to appear in Phys. Rev. Let

    Integration of highly probabilistic sources into optical quantum architectures: perpetual quantum computation

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    In this paper we introduce a design for an optical topological cluster state computer constructed exclusively from a single quantum component. Unlike previous efforts we eliminate the need for on demand, high fidelity photon sources and detectors and replace them with the same device utilised to create photon/photon entanglement. This introduces highly probabilistic elements into the optical architecture while maintaining complete specificity of the structure and operation for a large scale computer. Photons in this system are continually recycled back into the preparation network, allowing for a arbitrarily deep 3D cluster to be prepared using a comparatively small number of photonic qubits and consequently the elimination of high frequency, deterministic photon sources.Comment: 19 pages, 13 Figs (2 Appendices with additional Figs.). Comments welcom

    Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial by inhibiting neutrophil extracellular traps

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    IntroductionNeutrophil extracellular traps (NETs) clear pathogens but may contribute Q8 pathogenically to host inflammatory tissue damage during sepsis. Innovative therapeutic agents targeting NET formation and their potentially harmful collateral effects remain understudied.MethodsWe investigated a novel therapeutic agent, neonatal NET-Inhibitory Factor (nNIF), in a mouse model of experimental sepsis – cecal ligation and puncture (CLP). We administered 2 doses of nNIF (1 mg/ kg) or its scrambled peptide control intravenously 4 and 10 hours after CLP treatment and assessed survival, peritoneal fluid and plasma NET formation using the MPO-DNA ELISA, aerobic bacterial colony forming units (CFU) using serial dilution and culture, peritoneal fluid and stool microbiomes using 16S rRNA gene sequencing, and inflammatory cytokine levels using a multiplexed cytokine array. Meropenem (25 mg/kg) treatment served as a clinically relevant treatment for infection.ResultsWe observed increased 6-day survival rates in nNIF (73%) and meropenem (80%) treated mice compared to controls (0%). nNIF decreased NET formation compared to controls, while meropenem did not impact NET formation. nNIF treatment led to increased peritoneal fluid and plasma bacterial CFUs consistent with loss of NET-mediated extracellular microbial killing, while nNIF treatment alone did not alter the peritoneal fluid and stool microbiomes compared to vehicle-treated CLP mice. nNIF treatment also decreased peritoneal TNF-a inflammatory cytokine levels compared to scrambled peptide control. Furthermore, adjunctive nNIF increased survival in a model of sub-optimal meropenem treatment (90% v 40%) in CLP-treated mice.DiscussionThus, our data demonstrate that nNIF inhibits NET formation in a translationally relevant mouse model of sepsis, improves survival when given as monotherapy or as an adjuvant with antibiotics, and may play an important protective role in sepsis

    Physical and land-cover variables influence ant functional groups and species diversity along elevational gradients

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    Of particular importance in shaping species assemblages is the spatial heterogeneity of the environment. The aim of our study was to investigate the influence of spatial heterogeneity and environmental complexity on the distribution of ant functional groups and species diversity along altitudinal gradients in a temperate ecosystem (Pyrenees Mountains). During three summers, we sampled 20 sites distributed across two Pyrenean valleys ranging in altitude from 1,009 to 2,339 m by using pitfall traps and hand collection. The environment around each sampling points was characterized by using both physical and land-cover variables. We then used a self-organizing map algorithm (SOM, neural network) to detect and characterize the relationship between the spatial distribution of ant functional groups, species diversity, and the variables measured. The use of SOM allowed us to reduce the apparent complexity of the environment to five clusters that highlighted two main gradients: an altitudinal gradient and a gradient of environmental closure. The composition of ant functional groups and species diversity changed along both of these gradients and was differently affected by environmental variables. The SOM also allowed us to validate the contours of most ant functional groups by highlighting the response of these groups to the environmental and land-cover variables

    ‘Not All That Is White Is Lime’—White Substances from Archaeological Burial Contexts: Analyses and Interpretations

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    YesArchaeological burial contexts may include a variety of white substances, but few analyses have been published. This study reports on the physico‐chemical characterization of such residues from seven archaeological sites. It is often assumed that white materials from burial contexts are lime. Our findings demonstrate that they can be gypsum, calcite (chalk), aragonite, brushite, degraded metal, natural (gum) resins or synthetic polymer–based products. These may be present as the result of diagenetic processes, funerary practices or modern contamination. This paper provides an analytical approach for the holistic investigation of white materials encountered in burial contexts.Investments for the future’ (IdEx Bordeaux ANR‐10‐IDEX‐03‐02). Grant Number: ANR‐10‐IDEX‐03‐02; Collaborative Projects of the France‐Stanford Center for Interdisciplinary Studies; Collaborative Projects of the France–Stanford Center; French State. Grant Number: IdEx Bordeaux ANR‐10‐IDEX‐03‐02; Northern Archaeological Associates Ltd; PACEA; Wessex Archaeology; INRAP; Mersea Island Museum Trust; Vatican's Pontifical Commission for Sacred Archaeology; University of Reading; IRAMAT-CRP2A; University of Bradford; CEREG

    Landscape structure, human disturbance and crop management affect foraging ground selection by migrating geese

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    It is well known that agricultural intensification has caused severe population declines among bird species which use farmland for breeding and overwintering, while migrating bird species may benefit from intensive farming, but in turn damage crops. Knowledge of the habitat selection of migrating birds is important from both a conservation and agro-economic point of view. We investigated the habitat preferences of three common migrating goose species: White-fronted Goose Anser albifrons, Bean Goose A. fabalis and Greylag Goose A. anser during the autumn of 2009 in western Poland. A total of 24 flocks of these species were identified. Geese preferred large, elevated fields that were remote from forests and human settlements but in close proximity to a lake. Geese selected maize stubbles and avoided winter cereals. They selected sites in landscapes with a lower diversity of crops. Flock size was negatively correlated with the proportion of pastures in the landscape, but it increased with field size, distance to forest and distance to town. Our results are in contrast with the paradigm that less intensive farmland positively influences habitat use by birds during foraging. We advise the delayed ploughing of stubbles with the aim of creating appropriate foraging habitats for geese and minimizing damage to cereal crops
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