304 research outputs found
Cyclic metric Lie groups
Cyclic metric Lie groups are Lie groups equipped with a left-invariant metric
which is in some way far from being biinvariant, in a sense made explicit in
terms of Tricerri and Vanhecke's homogeneous structures. The semisimple and
solvable cases are studied. We extend to the general case, Kowalski-Tricerri's
and Bieszk's classifications of connected and simply-connected unimodular
cyclic metric Lie groups for dimensions less than or equal to five
On Not Taming the Wild Tongue: Challenges and Approaches to Institutional Translation in a University Serving a Historically Minoritized Population
A consequence of the development of modern states has been the concept of“minority” as used to refer to subsets of the population that are differentiated from that portion of the population which is seen as the “majority.” These minorities are at times distinguished from each other using terms such as national minorities and immigrant minorities. Some scholars have challenged the distinctions drawn by these constructs. An example of how such constructs are not always accurate can be found in Texas’ Rio Grande Valley, where ethnic and linguistic, immigrant and national, minority and majority are not always clear cut. “The Valley,” as the region is locally known, has a long history of the numerical majority being in a minoritized position. In this context, a local university administered a “speech test” to Mexican American studentswho enrolled between the 1950s and the 1970s. The purpose, according to Anzaldúa (1987), was to tame their “wild tongue.” This same university, now transformed, proposes to rehabilitate itself, as it becomes bilingual, bicultural,and biliterate. Accordingly, it now undertakes a systematic effort to bilingualize its operations, starting with the localization into Spanish of its website as conducted by the University of Texas Rio Grande Valley’s Translation and Interpreting Office. A number of terminological strategies and translation challenges stemming from the variegated lectal and diglossic landscapes of the region have arisen, which can be illuminated by the Post-Colonial paradigm found in Translation Studies
Carbon dioxide system in the Canary region during October 1995
During the cruise F/S Poseidon 212/3 (September 30-October 8, 1995) determination of carbon system variables was carried out over the section of La Palma-La Graciosa and at the ESTOC station in the Canary Island area. Total alkalinity and pH in the total scale at 25 degreesC were determined at 24 stations from surface to bottom. In this area, the presence of different water masses can be traced by the carbon system variables. NACW is defined by a strong gradient of A(T) and pH from 150 to 750 m. MW is characterised by high values of A(T) and pH between 1000 to 1200 in and AAIW signals are found at around 900 in in the strait between Gran Canaria and Fuerteventura with low A(T), low pH and a maximum of fCO(2). Assuming an atmospheric mean value of fCO(2) of 360 mu atm and an average surface value of 393 +/-7 mu atm, we can conclude that during this cruise this oceanic area tends to release CO2 into the atmosphere, acting as a weak source with a carbon flux towards the atmosphere of +8.0 +/-1.8 mmol.m(-2)d(-1). The saturation levels in the Canary Island area have been found to be higher than 3600 m for calcite and 2700 in for aragonite. The inorganic carbon/organic carbon ratio (IC/OC) varies from 0.07 at 300 m to 0.5 at 3000 m. The IC/OC ratio shows that about a 34% increase in the C-T of the deep water is contributed by the inorganic CaCO3 dissolution. The IC at 300 in is around 7 mu mol kg(-1), increasing with depth to 37.5 mu mol kg(-1) at 3700 m
SOOP Network Enhancement Report
Report on the network enhancement project, this will document (a) extension of network coverage to South Atlantic; (b) evaluation of improved EOV carbonate system; and (c) re-assessment of instrumentatio
New molecular approaches in adipogenesis regulation: The connexin 43 role
Indexación: Scopus; Redalyc.La prevalencia de la obesidad a nivel mundial se ha incrementado
rápidamente durante los últimos años debido principalmente
a los cambios en el estilo de vida de la población
con un aumento significativo en el consumo de energía y disminución
de los niveles de actividad física. Es por esto que
la comunidad científica está interesada en comprender de
forma más profunda los mecanismos que regulan la fisiopatología
de la obesidad. Dentro de los diferentes blancos de
estudio se encuentra la adipogénesis, cuyo entendimiento es
fundamental para comprender el desarrollo de la obesidad y
las patologías asociadas a esta. Recientemente ha surgido
importantes evidencias que involucran a la proteína de canales
de “Gap Junction” conexina 43 (Cx43) en la regulación
de los procesos relacionados con adipogénesis, cuyo papel
es básicamente anti-adipogénico, sin embargo, nuevas funciones
de Cx43 en la regulación de la formación del tejido
adiposo siguen descubriéndose.The global prevalence of obesity has been increased rapidly
over the past few years mainly due to changes in the lifestyle
of the population with a significant increase in energy
consumption and decreased levels of physical activity. As a
result, the scientific community is interested in a deeper understanding
of the mechanisms that regulate the pathophysiology
of obesity. In this context, adipogenesis process is an
important target of study to understand the obesity and associated
pathologies. Recently has been emerged important
evidence that involve gap junction channel protein connexin
43 (Cx43) in the regulation of processes related to adipogenesis,
whose role is fundamentally anti-adipogenic. However,
new functions of Cx43 in the regulation of adipose tissue
function also continued to emerge.http://www.redalyc.org/articulo.oa?id=5594990800
Regional differences in modelled net production and shallow remineralization in the North Atlantic subtropical gyre
© The Author(s), 2012. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Biogeosciences 9 (2012): 2831-2846, doi:10.5194/bg-9-2831-2012.We used 5-yr concomitant data of tracer distribution from the BATS (Bermuda Time-series Study) and ESTOC (European Station for Time-Series in the Ocean, Canary Islands) sites to build a 1-D tracer model conservation including horizontal advection, and then compute net production and shallow remineralization rates for both sites. Our main goal was to verify if differences in these rates are consistent with the lower export rates of particulate organic carbon observed at ESTOC. Net production rates computed below the mixed layer to 110 m from April to December for oxygen, dissolved inorganic carbon and nitrate at BATS (1.34±0.79 mol O2 m−2, −1.73±0.52 mol C m−2 and −125±36 mmol N m−2) were slightly higher for oxygen and carbon compared to ESTOC (1.03±0.62 mol O2 m−2, −1.42±0.30 mol C m−2 and −213±56 mmol N m−2), although the differences were not statistically significant. Shallow remineralization rates between 110 and 250 m computed at ESTOC (−3.9±1.0 mol O2 m−2, 1.53±0.43 mol C m−2 and 38±155 mmol N m−2) were statistically higher for oxygen compared to BATS (−1.81±0.37 mol O2 m−2, 1.52±0.30 mol C m−2 and 147±43 mmol N m−2). The lateral advective flux divergence of tracers, which was more significant at ESTOC, was responsible for the differences in estimated oxygen remineralization rates between both stations. According to these results, the differences in net production and shallow remineralization cannot fully explain the differences in the flux of sinking organic matter observed between both stations, suggesting an additional consumption of non-sinking organic matter at ESTOC.B. Mourino was supported by the
Ramon y Cajal program from the Spanish Minister of Science and
Technology. Funding for this study was provided by the Xunta de
Galicia under the research project VARITROP (09MDS001312PR,
PI B. Mourino) and by the Ministerio de Ciencia e Innovation
MOMAC project (CTM2008-05914/MAR)
Sharp Trace Hardy-Sobolev-Maz'ya Inequalities and the Fractional Laplacian
In this work we establish trace Hardy and trace Hardy-Sobolev-Maz'ya
inequalities with best Hardy constants, for domains satisfying suitable
geometric assumptions such as mean convexity or convexity. We then use them to
produce fractional Hardy-Sobolev-Maz'ya inequalities with best Hardy constants
for various fractional Laplacians. In the case where the domain is the half
space our results cover the full range of the exponent of the
fractional Laplacians. We answer in particular an open problem raised by Frank
and Seiringer \cite{FS}.Comment: 42 page
An assessment of the Atlantic and Arctic sea–air CO2 fluxes, 1990–2009
© The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Biogeosciences 10 (2013): 607-627, doi:10.5194/bg-10-607-2013.The Atlantic and Arctic Oceans are critical components of the global carbon cycle. Here we quantify the net sea–air CO2 flux, for the first time, across different methodologies for consistent time and space scales for the Atlantic and Arctic basins. We present the long-term mean, seasonal cycle, interannual variability and trends in sea–air CO2 flux for the period 1990 to 2009, and assign an uncertainty to each. We use regional cuts from global observations and modeling products, specifically a pCO2-based CO2 flux climatology, flux estimates from the inversion of oceanic and atmospheric data, and results from six ocean biogeochemical models. Additionally, we use basin-wide flux estimates from surface ocean pCO2 observations based on two distinct methodologies. Our estimate of the contemporary sea–air flux of CO2 (sum of anthropogenic and natural components) by the Atlantic between 40° S and 79° N is −0.49 ± 0.05 Pg C yr−1, and by the Arctic it is −0.12 ± 0.06 Pg C yr−1, leading to a combined sea–air flux of −0.61 ± 0.06 Pg C yr−1 for the two decades (negative reflects ocean uptake). We do find broad agreement amongst methodologies with respect to the seasonal cycle in the subtropics of both hemispheres, but not elsewhere. Agreement with respect to detailed signals of interannual variability is poor, and correlations to the North Atlantic Oscillation are weaker in the North Atlantic and Arctic than in the equatorial region and southern subtropics. Linear trends for 1995 to 2009 indicate increased uptake and generally correspond between methodologies in the North Atlantic, but there is disagreement amongst methodologies in the equatorial region and southern subtropics.U. Schuster has been supported by
EU grants IP 511176-2 (CARBOOCEAN), 212196 (COCOS), and
264879 (CARBOCHANGE), and UK NERC grant NE/H017046/1
(UKOARP). G. A. McKinley and A. Fay thank NASA for support
(NNX08AR68G, NNX11AF53G). P. Landsch¨utzer has been
supported by EU grant 238366 (GREENCYCLESII). N. Metzl
acknowledges the French national funding program LEFE/INSU.
Support for N. Gruber has been provided by EU grants 264879
(CARBOCHANGE) and 283080 (GEO-CARBON) S. Doney
acknowledges support from NOAA (NOAA-NA07OAR4310098).
T. Takahashi is supported by NOAA (NAO80AR4320754)
Monoclonal gammopathy of renal significance (MGRS): Real-world data on outcomes and prognostic factors
Monoclonal gammopathy of renal significance (MGRS) is a recognized clinical entity. Literature regarding treatment and its outcomes in MGRS is sparse due to the rarity and misdiagnosis of MGRS. We retrospectively analyzed 280 adults with an MGRS diagnosis from 2003 to 2020 across 19 clinical centers from 12 countries. All cases required renal biopsy for the pathological diagnosis of MGRS. Amyloidosis-related to MGRS (MGRS-A) was present in 180 patients; nonamyloidosis MGRS (MGRS-NA), including a broad spectrum of renal pathologies, was diagnosed in 100 patients. The median overall survival in the studied cohort was 121.0 months (95% CI: 105.0–121.0). Patients with MGRS-A had a shorter overall survival than patients with MGRS-NA (HR = 0.41, 95%CI: 0.25–0.69; p = 0.0007). Both hematologic and renal responses were associated with longer survival. Achievement of ≥VGPR was generally predictive of a renal response (OR = 8.03 95%CI: 4.04–115.96; p < 0.0001), one-fourth of patients with ≥VGPR were renal nonresponders. In MGRS-A, factors associated with poor prognosis included elevated levels of creatinine, beta-2-microglobulin, and hemodialysis at diagnosis. In MGRS-NA, only age >65 years was associated with increased risk of death. Treatments provided similar hematologic response rates in both types of MGRS. Autologous stem cell transplantation led to better response than other treatments. This multicenter and international effort is currently the largest report on MGRS
- …