317 research outputs found
Simulation and evaluation of a new PET system based on liquid xenon as detection medium
présenté par J.P. CussoneauDue to its intrinsic physical properties, high density and atomic number, fast scintillation, high scintillation light yield and low ionization potential, liquid xenon is an excellent medium for the tracking and the accurate energy measurement of γ-rays in the MeV energy domain. The use of liquid xenon associated to a micro gap structure device[1] to measure 511 keV γ-rays in PET system is under investigation at Subatech. A Geant3 simulation of a full PET design made of lXe-TPC modules has been developed and the first estimations of the performances from a realistic detector are very promising: good overall sensitivity to 511 keV γ's (~ 93% for a 9 cm lXe module), good three-dimensional spatial resolution (250 µm FWHM, for first interaction vertex localization). The measurement of the 3 coordinates of the interaction vertices and the energy loss associated allow to reconstruct the correct Compton sequence of correlated annihilation γ-rays. Hence the capability to identify the first interaction vertex leads to major progresses in PET imaging: a parallax free PET tomograph with high detection sensitivity and spatial resolution. Moreover, such lXe-PET camera have an excellent rejection power on scattered events in 3D reconstruction mode
A proposal for a high performance -camera based on liquid Xenon converter and gaseous photomultiplier for PET
présenté par D. Ther
Specific shifts in the endocannabinoid system in hibernating brown bears
In small hibernators, global downregulation of the endocannabinoid system (ECS), which is involved in modulating neuronal signaling, feeding behavior, energy metabolism, and circannual rhythms, has been reported to possibly drive physiological adaptation to the hibernating state. In hibernating brown bears (Ursus arctos), we hypothesized that beyond an overall suppression of the ECS, seasonal shift in endocannabinoids compounds could be linked to bear's peculiar features that include hibernation without arousal episodes and capacity to react to external disturbance. We explored circulating lipids in serum and the ECS in plasma and metabolically active tissues in free-ranging subadult Scandinavian brown bears when both active and hibernating. In winter bear serum, in addition to a 2-fold increase in total fatty acid concentration, we found significant changes in relative proportions of circulating fatty acids, such as a 2-fold increase in docosahexaenoic acid C22:6 n-3 and a decrease in arachidonic acid C20:4 n-6. In adipose and muscle tissues of hibernating bears, we found significant lower concentrations of 2-arachidonoylglycerol (2-AG), a major ligand of cannabinoid receptors 1 (CB1) and 2 (CB2). Lower mRNA level for genes encoding CB1 and CB2 were also found in winter muscle and adipose tissue, respectively. The observed reduction in ECS tone may promote fatty acid mobilization from body fat stores, and favor carbohydrate metabolism in skeletal muscle of hibernating bears. Additionally, high circulating level of the endocannabinoid-like compound N-oleoylethanolamide (OEA) in winter could favor lipolysis and fatty acid oxidation in peripheral tissues. We also speculated on a role of OEA in the conservation of an anorexigenic signal and in the maintenance of torpor during hibernation, while sustaining the capacity of bears to sense stimuli from the environment
Comment on "On the subtleties of searching for dark matter with liquid xenon detectors"
In a recent manuscript (arXiv:1208.5046) Peter Sorensen claims that
XENON100's upper limits on spin-independent WIMP-nucleon cross sections for
WIMP masses below 10 GeV "may be understated by one order of magnitude or
more". Having performed a similar, though more detailed analysis prior to the
submission of our new result (arXiv:1207.5988), we do not confirm these
findings. We point out the rationale for not considering the described effect
in our final analysis and list several potential problems with his study.Comment: 3 pages, no figure
Lowering the radioactivity of the photomultiplier tubes for the XENON1T dark matter experiment
The low-background, VUV-sensitive 3-inch diameter photomultiplier tube R11410
has been developed by Hamamatsu for dark matter direct detection experiments
using liquid xenon as the target material. We present the results from the
joint effort between the XENON collaboration and the Hamamatsu company to
produce a highly radio-pure photosensor (version R11410-21) for the XENON1T
dark matter experiment. After introducing the photosensor and its components,
we show the methods and results of the radioactive contamination measurements
of the individual materials employed in the photomultiplier production. We then
discuss the adopted strategies to reduce the radioactivity of the various PMT
versions. Finally, we detail the results from screening 216 tubes with
ultra-low background germanium detectors, as well as their implications for the
expected electronic and nuclear recoil background of the XENON1T experiment.Comment: 10 pages, 5 figure
Search for Event Rate Modulation in XENON100 Electronic Recoil Data
We have searched for periodic variations of the electronic recoil event rate
in the (2-6) keV energy range recorded between February 2011 and March 2012
with the XENON100 detector, adding up to 224.6 live days in total. Following a
detailed study to establish the stability of the detector and its background
contributions during this run, we performed an un-binned profile likelihood
analysis to identify any periodicity up to 500 days. We find a global
significance of less than 1 sigma for all periods suggesting no statistically
significant modulation in the data. While the local significance for an annual
modulation is 2.8 sigma, the analysis of a multiple-scatter control sample and
the phase of the modulation disfavor a dark matter interpretation. The
DAMA/LIBRA annual modulation interpreted as a dark matter signature with
axial-vector coupling of WIMPs to electrons is excluded at 4.8 sigma.Comment: 6 pages, 4 figure
Removing krypton from xenon by cryogenic distillation to the ppq level
The XENON1T experiment aims for the direct detection of dark matter in a
cryostat filled with 3.3 tons of liquid xenon. In order to achieve the desired
sensitivity, the background induced by radioactive decays inside the detector
has to be sufficiently low. One major contributor is the -emitter
Kr which is an intrinsic contamination of the xenon. For the XENON1T
experiment a concentration of natural krypton in xenon Kr/Xe < 200
ppq (parts per quadrillion, 1 ppq = 10 mol/mol) is required. In this
work, the design of a novel cryogenic distillation column using the common
McCabe-Thiele approach is described. The system demonstrated a krypton
reduction factor of 6.410 with thermodynamic stability at process
speeds above 3 kg/h. The resulting concentration of Kr/Xe < 26 ppq
is the lowest ever achieved, almost one order of magnitude below the
requirements for XENON1T and even sufficient for future dark matter experiments
using liquid xenon, such as XENONnT and DARWIN
Search for Two-Neutrino Double Electron Capture of Xe with XENON100
Two-neutrino double electron capture is a rare nuclear decay where two
electrons are simultaneously captured from the atomic shell. For Xe
this process has not yet been observed and its detection would provide a new
reference for nuclear matrix element calculations. We have conducted a search
for two-neutrino double electron capture from the K-shell of Xe using
7636 kgd of data from the XENON100 dark matter detector. Using a
Bayesian analysis we observed no significant excess above background, leading
to a lower 90 % credibility limit on the half-life
yr. We also evaluated the sensitivity of the XENON1T experiment, which is
currently being commissioned, and find a sensitivity of
yr after an exposure of 2 tyr.Comment: 6 pages, 4 figure
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