10 research outputs found
Urban tree biomass estimation in Universiti Putra Malaysia (UPM) campus.
- Publication venue
- Publication date
- 01/01/2011
- Field of study
Biomass is a renewable energy source refers to living and recently dead biological materials that can reduce green house effect and clean surroundings. To estimate tree biomass individually from imagery, it is necessary to clarify the relationship between attributes of stand structure obtained by field measurement and remote sensing image.This study was carried out to estimate tree biomass in Universiti Putra Malaysia (UPM) campus. Five plots were established (40 m x 40 m) and all trees with diameters at breast high (dbh) more than 30 cm , tree height and canopy size were measured. Each trees biomass were calculated by non-destructive method. Results show that tree volume is ranged from 1.75 m3 to 24.73 m3, wood density is ranged from 0.99 t/m3 to 14.10 t/m3. The overall wood densities for five plots (30 trees) are 23.35 t/m3. Meanwhile the biomass estimated is 7,644 t/ha. Study demonstrate strong correlations (p < 0.05) between field measurement and IKONOS tree canopy estimates (r2 = 0.95). The results obtained from the analysis are encouraging especially canopy measurement where it can be incorporated to the existing mensuration models. Estimating tree biomass through satellite images are recommended because remote sensing through image processing has potential to estimate biomass in large area
A common variant near TGFBR3 is associated with primary open angle glaucoma
- Author
- (ANZgene)
- Alex W. Hewitt
- Allingham
- Allison E. Ashley Koch
- Anil K. Negi
- Anita S.Y. Chan
- Augusto Azuara Blanco
- Aurelien Goncalves
- Azhany Yakub
- Balekudaru Shantha
- Barrett
- Baskaran Mani
- Blanche Lim
- Blobe
- Bonnefond
- Bowen Zhao
- Burdon
- Cai
- Cameron P. Simmons
- Cao
- Changwon Kee
- Chen
- Chi Pui Pang
- Chiea-Chuen Khor
- Ching Yu Cheng
- Ching-Lin Ho
- Christopher A. Girkin
- Christopher K.S. Leung
- Chukai Huang
- Dan Milea
- Daniel H Su
- David A. Mackey
- David Broadway
- David F. Garway-Heath
- David Goh
- Diestel
- Do Nhu Hon
- Douglas E. Gaasterland
- E-Shyong Tai
- Elaine Chua
- Eranga N. Vithana
- Essam A. Osman
- Fan
- Fan
- Fan
- Fingert
- Fingert
- Fuchshofer
- Garway-Heath
- Gharahkhani
- Hannon
- Hirschhorn
- Hoglinger
- Hong Zhang
- Huyghe
- Hysi
- Ihaka
- Jae H. Kang
- Jamie E. Craig
- Janey L. Wiggs
- Jessica N. Cooke Bailey
- Jia Nee Foo
- Jianjun Liu
- Jin-Xin Bei
- Jinghong Sang
- Jonathan L. Haines
- Jong Chul Han
- Jost B. Jonas
- Julia E. Richards
- Kang
- Kathryn Burdon
- Kazuhiko Mori
- Kei Tashiro
- Kengo Yoshii
- Khaled K. Abu-Amero
- Khor
- Khor
- Kooner
- Lee
- Leon W. Herndon
- Li-Jia Chen
- Lingam Vijaya
- Liyun Jia
- Liza-Sharmini A. Tajudin
- Louis R. Pasquale
- Lu
- Masakazu Nakano
- Massague
- Mei Chin Lee
- Merwyn Chew
- Michael A. Hauser
- Mineo Ozaki
- Mingzhi Zhang
- Monemi
- Monisha E. Nongpiur
- Morio Ueno
- Nakano
- Nalls
- NiHong Zhang
- Ningli Wang
- Nobuo Fuse
- Pansy O.S. Tam
- Pascal Reynier
- Pasmant
- Pasquale
- Pena
- Periasamy Sundaresan
- Philomenadin Ferdinamarie Sharmila
- Prasanthi Namburi
- Pratap Challa
- Price
- Purcell
- Puya Gharahkhani
- Quigley
- Quigley
- R. Rand Allingham
- Rahat Husain
- Ramdas
- Reveille
- Rezaie
- Robert Ritch
- Ronnie George
- Rupert Bourne
- Ryuichi Sato
- Saleh A. Al-Obeidan
- Sarangapani Sripriya
- Saravanan Vijayan
- Sarfarazi
- Sawcer
- Sayoko E. Moroi
- Seang-Mei Saw
- Shamira A. Perera
- Sheffield
- Shigeru Kinoshita
- Sohn Seongsoo
- Songhomita Panda-Jonas
- Springelkamp
- Stone
- Stuart Macgregor
- Subbiah Ramasamy Krishnadas
- Takanori Mizoguchi
- Tan Do
- Tham
- Thorleifsson
- Tien Yin Wong
- Tin Aung
- Tina T. Wong
- Tran Nguyen Bich Chau
- Victor H.K. Yong
- Vithana
- Wang Xu
- Wee Yang Meah
- Wiggs
- Wiggs
- Xiao Yu Ng
- Xinghuai Sun
- Yaan Fun Chong
- Yi-Xin Zeng
- Yik Ying Teo
- Ying Lin
- Yoko Ikeda
- Yuhong Chen
- Yutao Liu
- Zheng Li
- Zhenglin Yang
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2015
- Field of study
Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex disease with a significant genetic contribution. We performed Exome Array (Illumina) analysis on 3504 POAG cases and 9746 controls with replication of the most significant findings in 9173 POAG cases and 26 780 controls across 18 collections of Asian, African and European descent. Apart from confirming strong evidence of association at CDKN2B-AS1 (rs2157719 [G], odds ratio [OR] = 0.71, P = 2.81 × 10−33), we observed one SNP showing significant association to POAG (CDC7–TGFBR3 rs1192415, ORG-allele = 1.13, Pmeta = 1.60 × 10−8). This particular SNP has previously been shown to be strongly associated with optic disc area and vertical cup-to-disc ratio, which are regarded as glaucoma-related quantitative traits. Our study now extends this by directly implicating it in POAG disease pathogenesis
Downloaded from
- Author
- Alex W Hewitt
- Allison E Ashley Koch
- Anil K Negi
- Anita S Y Chan
- Augusto Azuara Blanco
- Aurelien Goncalves
- Azhany Yakub
- Balekudaru Shantha
- Baskaran Mani
- Bich Chau
- Blanche Lim
- Bowen Zhao
- Cameron P Simmons
- Changwon Kee
- Chi Pui Pang
- Chiea-Chuen Khor
- Ching Yu Cheng
- Ching-Lin Ho
- Christopher A Girkin
- Christopher K S Leung
- Chukai Huang
- Dan Milea
- Daniel H Su
- David A Mackey
- David Broadway
- David F Garway-Heath
- David Goh
- Do Nhu Hon
- E-Shyong Tai
- Elaine Chua
- Eranga N Vithana
- Essam A Osman
- Hong Zhang
- Jae H Kang
- Jamie E Craig
- Janey L Wiggs
- Jessica N Cooke Bailey
- Jia Nee Foo
- Jianjun Liu
- Jin-Xin Bei
- Jinghong Sang
- Jonathan L Haines
- Jong Chul Han
- Jost B Jonas
- Kathryn Burdon
- Kazuhiko Mori
- Kei Tashiro
- Kengo Yoshii
- Khaled K Abu-Amero
- Leon W Herndon
- Li-Jia Chen
- Lingam Vijaya
- Liyun Jia
- Liza-Sharmini A Tajudin
- Louis R Pasquale
- Masakazu Nakano
- Mei Chin Lee
- Merwyn Chew
- Michael A Hauser
- Mineo Ozaki
- Mingzhi Zhang
- Minh City
- Monisha E Nongpiur
- Morio Ueno
- Nihong Zhang
- Ningli Wang
- Nobuo Fuse
- Pansy O S Tam
- Pascal Reynier
- Periasamy Sundaresan
- Philomenadin Ferdinamarie
- Prasanthi Namburi
- Pratap Challa
- Puya Gharahkhani
- R Rand Allingham
- Rahat Husain
- Ronnie George
- Rupert Bourne
- Ryuichi Sato
- Saleh A Al-Obeidan
- Sarangapani Sripriya
- Saravanan Vijayan
- Sayoko E Moroi
- Seang-Mei Saw
- Shamira A Perera
- Sharmila 17
- Shigeru Kinoshita
- Sohn Seongsoo
- Songhomita Panda-Jonas
- Stuart Macgregor
- Subbiah Ramasamy Krishnadas
- Takanori Mizoguchi
- Tan Do
- Tien Yin Wong
- Tin Aung
- Tina T Wong
- Tran Nguyen
- Victor H K Yong
- Vietnam
- Wang Xu
- Wee Yang Meah
- Xiao Yu Ng
- Xinghuai Sun
- Yaan Fun Chong
- Yi-Xin Zeng
- Yik Ying Teo
- Ying Lin
- Yoko Ikeda
- Yuhong Chen
- Yutao Liu
- Zheng Li
- Zhenglin Yang
- Publication venue
- Publication date
- 01/05/2020
- Field of study
Abstract Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex disease with a significant genetic contribution. We performed Exome Array ), we observed one SNP showing significant association to POAG (CDC7-TGFBR3 rs1192415, OR G-allele = 1.13, P meta = 1.60 × 10 −8 ). This particular SNP has previously been shown to be strongly associated with optic disc area and vertical cup-to-disc ratio, which are regarded as glaucoma-related quantitative traits. Our study now extends this by directly implicating it in POAG disease pathogenesis
Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study
- Author
- Aung Tin
- Bei Jin-Xin
- Cai Qing-Qing
- Chen Jie-Rong
- Chen Li Jia
- Chen Li-Zhen
- Chew Soo Hong
- Chin Suk Teng
- Chng Wee Joo
- Chowbay Balram
- Cui Jing
- Diong Colin Phipps
- Ebstein Richard P
- Feng Li-Na
- Feng Qi-Sheng
- Foo Jia Nee
- Guo Yun-Miao
- Ha Jeslin
- Khoo Lay Poh
- Khor Chiea Chuen
- Laurensia Yurike
- Li Hong-Min
- Li Zheng
- Lim Soon Thye
- Liu Jianjun
- Liu Wen-Sheng
- Liu Yan-Hui
- Meah Wee Yang
- Mohamad Farid
- Nairismagi Maarja-Liisa
- Ng Siok Bian
- Okada Yukinori
- Ong Choon Kiat
- Pang Chi Pui
- Peng Rou-Jun
- Quek Richard
- Raychaudhuri Soumya
- Sim Kar Seng
- Tan Soo Yong
- Tan Wen
- Tang Tiffany
- Tao Miriam
- Teh Bin Tean
- Xia Yi
- Zeng Yi-Xin
- Zhang Fen
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/11/2021
- Field of study
10.1016/S1470-2045(16)30148-6LANCET ONCOLOGY1791240-1247United State
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error
- Author
- Abhishek Nag
- Ahmad Fahmy
- Akira Meguro
- Alan Sugar
- Alan F. Wright
- Albert Hofman
- Alex W. Hewitt
- Ali Djalilian
- Alireza Mirshahi
- Andres Metspalu
- Andrew D. Paterson
- André G. Uitterlinden
- Aniket Mishra
- Ann Renucci
- Anthony Aldave
- Aulchenko
- B.J. Dupps
- Barathi
- Barathi
- Baratz
- Barbara E. Klein
- Bartly J. Mondino
- Beate St. Pourcain
- Ben A. Oostra
- Biino
- Boyd
- Boyle
- Brandon Ayres
- Brandon Suedekum
- Brian Fleck
- Brink
- Brockschmidt
- Burdon
- Carol Karp
- Caroline C.W. Klaver
- Cathy Williams
- Chen
- Chi Pui Pang
- Chiea-Chuen Khor
- Ching-Yu Cheng
- Christopher Croasdale
- Christopher J. Hammond
- Christopher Rapuano
- Claire L. Simpson
- Cornelia M. van Duijn
- Craig E. Pennell
- David A. Mackey
- David Bardenstein
- David G. Heidemann
- David Hwang
- David M. Meisler
- David R. Hardten
- David Verdier
- David M. Evans
- Dirani
- Dirani
- Donald Stone
- Dwight Stambolian
- E-Shyong Tai
- Eduardo Alfonso
- Ekaterina Yonova-Doing
- Elena Rochtchina
- Elisabeth Cohen
- Elisabeth M. van Leeuwen
- Elizabeth A. Davis
- Elmer Tu
- Emily Y. Chew
- Eranga Vithana
- Evans
- Evelin Mihailov
- Fan
- Faye Peters
- Fernando Rivadeneira
- Foong
- Foran
- Francis Price
- Fraser
- Fuhrmann
- Fumihiko Matsuda
- Gary Holland
- George McMahon
- George Rosenwasser
- Goran Bencic
- Grant W. Montgomery
- Guggenheim
- Guggenheim
- Guo
- H. Dwight Cavanaugh
- Hannah Forward
- Hao
- Harry Campbell
- Hemin Chin
- Hidetoshi Inoko
- Higgins
- Hofman
- Holle
- Howie
- Hsiang
- Hsu
- Hunson Kaz Soong
- Igor Rudan
- Ingrid Borecki
- Ip
- James Caudill
- James Chodosh
- James McCulley
- James F. Wilson
- Jamie E. Craig
- Javitt
- Jeremy A. Guggenheim
- Jiemin Liao
- Jie Jin Wang
- Jing Hua Zhao
- Joan E. Bailey-Wilson
- Joel Sugar
- Johannes R. Vingerling
- John P. Kemp
- Jonathan H. Lass
- Juho Wedenoja
- Kari-Matti Makela
- Karl J. Lackner
- Kathleen Kelly
- Kathryn Colby
- Kathryn P. Burdon
- Katie M. Williams
- Katrina Goddard
- Keith Baratz
- Kim
- Klein
- Klein
- Konrad Oexle
- Kristin Hammersmith
- Laura Portas
- Lavanya
- Leibowitz
- Leo Maguire
- Li
- Li Jia Chen
- Liang Xu
- Lim
- Lin
- Liu
- Louttit
- Lu
- Lyhne
- M. Kamran Ikram
- Mackey
- Marchini
- Maria Schache
- Marianne Price
- Mario Pirastu
- Mark Gorovoy
- Mark Mannis
- Mark Mifflin
- Mark Terry
- Mark Vital
- Marlene Brown
- Matt Oliva
- Maurice K.H. Yap
- Merwyn Chew
- Michael Shaughnessy
- Michael W. Belin
- Mika Kahonen
- Mitchell
- Nagahisa Yoshimura
- Najaf Amin
- Neda Shamie
- Nelis
- Newnham
- Nicholas J. Timpson
- Nobuhisa Mizuki
- Norbert Pfeiffer
- Oexle
- Olavi Pärssinen
- Olli Raitakari
- Ozren Polasek
- Pan
- Pardo
- Pascolini
- Paul G. Galentine
- Paul J. Foster
- Paul Mitchell
- Paul N. Baird
- Paulus T.V.M. de Jong
- Peng Chen
- Peter Laibson
- Pirro G. Hysi
- Pärssinen
- Qiao Fan
- Rahi
- Raitakari
- Randal Olson
- René Höhn
- Richard Lindstrom
- Richard Yee
- Robert L. Schultze
- Robert P. Igo
- Robert Wojciechowski
- Rohit Varma
- Ronald Klein
- Rozen
- Ruoying Li
- S. Mohsen Hosseini
- Sanfilippo
- Sanjay Patel
- Saw
- Saw
- Saw
- Scott Hauswirth
- Seang-Mei Saw
- Shahzad Mian
- Shea Ping Yip
- Sherman Reeves
- Shiels
- Shufelt
- Sim
- Solouki
- Sonia Yoo
- Spector
- Steffens
- Stephen Hamilton
- Stephens
- Steven I. Rosenfeld
- Steven P. Dunn
- Steven Verity
- Stuart MacGregor
- Sudha K. Iyengar
- Tanja Zeller
- Terho Lehtimaki
- Terri L. Young
- Thomas Bettecken
- Thomas Meitinger
- Thomas Steinemann
- Tien-Yin Wong
- Tin Aung
- Todd Morason
- Toomas Haller
- Ula Jurkunas
- Veluchamy A. Barathi
- Verhoeven
- Verhoeven
- Veronique Vitart
- Vinod Mootha
- Virginie J.M. Verhoeven
- Vitale
- Vitart
- Vitart
- Vithana
- W. Barry Lee
- Walter Rotkis
- Wan-Ting Tay
- Ward
- Wayne Bowman
- Wichmann
- William Bourne
- William Reinhart
- Williams
- Wong
- Wong
- Xin Zhou
- Xu
- Ya Xing Wang
- Yik-Ying Teo
- Yingfeng Zheng
- Yunhee Lee
- Zheng
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2013
- Field of study
10.1016/j.ajhg.2013.06.016American Journal of Human Genetics932264-277AJHG
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
- Author
- AA Al Olama
- Abhilasha Karkey
- Ahmad Tajudin Liza-Sharmini
- Alex W Hewitt
- Alexander C Day
- Aliza Jap
- Anavaj Sakuntabhai
- Anita Manassakorn
- Anita S Chan
- Anneke I den Hollander
- Antonio Fea
- Anuwat Prutthipongsit
- AP Boyle
- Arkasubhra Ghosh
- Aye Thi Han
- B Thylefors
- Balekudaru Shantha
- Bonnie N K Choy
- Boon-Ang Lim
- Boonsong Wanichwecharungruang
- BP Fairfax
- Bruno B de Souza
- Buddha Basnyat
- Carlo Lavia
- CC Gregorio-King
- Celso Tello
- Chan-Yun Kim
- Chaw Chaw Khaing
- Chelvin C Sng
- Chi Pui Pang
- Chiea Chuen Khor
- Ching-Lin Ho
- Ching-Yu Cheng
- Chona S Liao
- Christine A Kiire
- Chunyan Qiao
- Clement C Tham
- Curt Hartleben-Matkin
- CY Cheng
- Daniel H Su
- Daniela Paoli
- David Goh
- David Lozano-Giral
- Deepak P Edward
- Desmond T Quek
- DF Gudbjartsson
- Donald T Tan
- DY Wang
- E Randy Craven
- E-Shyong Tai
- Edgar U Leuenberger
- Eileen Png
- EK Speliotes
- Emma Rusmayani
- EN Vithana
- Eng Hui Gan
- Eranga N Vithana
- Ewa Kosior-Jarecka
- Farah Akhtar
- Francesca Pasutto
- GH Dolmans
- Giulia Consolandi
- Giulia Pignata
- Greet Boland
- Guangxian Tang
- Guillermo Barreto Fong
- HA Quigley
- HA Quigley
- Hailin Meng
- Harm Snippe
- Hiroshi Sakai
- HJ Westra
- Hlaing May Than
- Hon-Tym Wong
- Hongyan Jia
- Huaizhou Wang
- Huan Nguyen Pham
- Humaira Ayub
- Huong T T Bui
- Hyoung Won Bae
- Irene R Felarca
- J Dupuis
- Jamie E Craig
- Jamil Miguel Neto
- JC Barrett
- Jeanne Ogle
- Jeeyun Ahn
- Jelinar Mohamed-Noor
- Jennifer W H Shum
- Jia Nee Foo
- Jie Jin Wang
- Jimmy S M Lai
- Jin Wook Jeoung
- Jinxin Bei
- JL Wiggs
- John F Salmon
- John H Fingert
- Jonathan C H Chan
- Jose Maria Martinez
- Jost B Jonas
- José P C de Vasconcellos
- Jovell Ian M Peregrino
- JS Mandak
- Juan C Zenteno
- JW Cheng
- K Kiryluk
- Kar Seng Sim
- Kathryn P Burdon
- Kazuhiko Mori
- Kei Tashiro
- Kessara Pathanapitoon
- Khaled Abu-Amero
- Khin Thida Oo
- Ki-Ho Park
- KP Burdon
- Kuldeep Mohanty
- Kyu Hyung Park
- L Dandona
- L Shi
- Laura Dallorto
- LD Ward
- Leonard W Yip
- Lerprat Mangkornkanokpong
- Leyla A Aljasim
- Li Jia Chen
- Liang Xu
- Lingam Vijaya
- Manchima Makornwattana
- Mani Baskaran
- Maria C Aquino
- Maria L Guevara-Fujita
- Mark Seielstad
- Martin L Hibberd
- Mary Ann T Catacutan
- Masakazu Nakano
- Masako Kuroda
- ME Nongpiur
- ME Nongpiur
- Mei-Chin Lee
- Michael A Hauser
- Michiko Yonahara
- Mimiwati Zahari
- Mineo Ozaki
- MM Pomerantz
- Mona S Awadalla
- Monisha E Nongpiur
- Morio Ueno
- MP Purdue
- Muhammad Imran Khan
- Muneeb A Faiq
- Mônica Barbosa de Melo
- Nagaswamy Soumittra
- Naris Kitnarong
- Naushin Waseem
- Nay Lin Oo
- Nguyen Van Vinh Chau
- Nhu Hon Do
- Ningli Wang
- Norlina Ramli
- Nuttamon Srisamran
- Owen Hee
- P Gharahkhani
- Pancy O S Tam
- Paolo Frezzotti
- Paul J Foster
- Paul Mitchell
- Paul T K Chew
- Periasamy Sundaresan
- PG Hysi
- PJ Foster
- PJ Foster
- PJ Foster
- Prin Rojanapongpun
- PT Ellinor
- R Barone
- R Rand Allingham
- Rahat Husain
- Raheel Qamar
- Rajesh S Kumar
- Ramanjit Sihota
- Raquel Quino
- Rengaraj Venkatesh
- Renyi Wu
- Ricardo Fujita
- Ricardo Y Abe
- Richard P Ebstein
- Richard Stead
- Rigo Daniel Reyes
- Robert Ritch
- Rodolfo A Perez-Grossmann
- Rohit Shetty
- Ronnie George
- Roopam Duvesh
- Rrima Dada
- S Tuupanen
- Saleh Al-Obeidan
- Sami Al-Shahwan
- Sancy Low
- Sarah J Dunstan
- Saravanan Vijayan
- Satoko Nakano
- Saw Htoo Set
- Seang Mei Saw
- Seng Kheong Fang
- Seng-Chee Loon
- Shamira A Perera
- Shazia Micheal
- Shigeru Kinoshita
- Shomi S Bhattacharya
- Shuang Ru Goh
- SJ Dunstan
- Soo Hong Chew
- Soon Thye Lim
- Srinivasan Kavitha
- Sripriya Sarangapani
- Stephen A Vernon
- Su Nyunt Zaw
- Subbiah R Krishnadas
- Sujie Fan
- Suman S Thapa
- Sunee Chansangpetch
- T Aung
- Takanori Mizoguchi
- Tam Thi Luu
- Tan Do
- Tanuj Dada
- Thanh Thu Nguyen
- Thayanithi Sandragasu
- Thi Lam Huong Dao
- Thi Thuy Giang Nguyen
- Thipnapa Patthanathamrongkasem
- Tien Dat Tran
- Tien Y Wong
- Tin Aung
- Tina T Wong
- Tomasz Zarnowski
- Toshiaki Kubota
- Tuan Anh Tran
- Tung S Hoan
- Tuyet Bach Trinh
- Urszula Lukasik
- V Senée
- Vania Castro Tamanaja
- Vernon K Yong
- Vi Huyen Doan
- Victor H Yong
- Vira Wardhana Istiantoro
- Visanee Tantisevi
- Vital P Costa
- VJ Verhoeven
- Widya Artini Wiyogo
- Wing Lau Ho
- Xiao Yin Chen
- Xiao-Yu Ng
- Y Chen
- Y Lachkar
- Y Okada
- Ya-Xing Wang
- Yaakub Azhany
- Yaan Fun Chong
- Yasuo Kurimoto
- Yee Yee Aung
- Yi Xin Zeng
- Yik Y Teo
- Yin Mon Aung
- Yoko Ikeda
- Yong Ho Sohn
- Young Hoon Hwang
- YS Cho
- YS Kim
- Yuzhen Jiang
- Z Li
- Z Shen
- Zeiras Eka Djamal
- Zheng Li
- Zhicheng Xie
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe, North America, and South America. We observed significant evidence of disease association at five new genetic loci upon meta-analysis of all patient collections. These loci are at EPDR1 rs3816415 (odds ratio (OR) = 1.24, P = 5.94 × 10(-15)), CHAT rs1258267 (OR = 1.22, P = 2.85 × 10(-16)), GLIS3 rs736893 (OR = 1.18, P = 1.43 × 10(-14)), FERMT2 rs7494379 (OR = 1.14, P = 3.43 × 10(-11)), and DPM2-FAM102A rs3739821 (OR = 1.15, P = 8.32 × 10(-12)). We also confirmed significant association at three previously described loci (P < 5 × 10(-8) for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1-ST18), providing new insights into the biology of PACG
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma
- Author
- AA Al Olama
- Abhilasha Karkey
- Ahmad Tajudin Liza-Sharmini
- Alex W Hewitt
- Alexander C Day
- Aliza Jap
- Anavaj Sakuntabhai
- Anita Manassakorn
- Anita S Chan
- Anneke I den Hollander
- Antonio Fea
- Anuwat Prutthipongsit
- AP Boyle
- Arkasubhra Ghosh
- Aye Thi Han
- B Thylefors
- Balekudaru Shantha
- Bonnie N K Choy
- Boon-Ang Lim
- Boonsong Wanichwecharungruang
- BP Fairfax
- Bruno B de Souza
- Buddha Basnyat
- Carlo Lavia
- CC Gregorio-King
- Celso Tello
- Chan-Yun Kim
- Chaw Chaw Khaing
- Chelvin C Sng
- Chi Pui Pang
- Chiea Chuen Khor
- Ching-Lin Ho
- Ching-Yu Cheng
- Chona S Liao
- Christine A Kiire
- Chunyan Qiao
- Clement C Tham
- Curt Hartleben-Matkin
- CY Cheng
- Daniel H Su
- Daniela Paoli
- David Goh
- David Lozano-Giral
- Deepak P Edward
- Desmond T Quek
- DF Gudbjartsson
- Donald T Tan
- DY Wang
- E Randy Craven
- E-Shyong Tai
- Edgar U Leuenberger
- Eileen Png
- EK Speliotes
- Emma Rusmayani
- EN Vithana
- Eng Hui Gan
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- Owen Hee
- P Gharahkhani
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- Periasamy Sundaresan
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- Thi Thuy Giang Nguyen
- Thipnapa Patthanathamrongkasem
- Tien Dat Tran
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- Tin Aung
- Tina T Wong
- Tomasz Zarnowski
- Toshiaki Kubota
- Tuan Anh Tran
- Tung S Hoan
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- Urszula Lukasik
- V Senée
- Vania Castro Tamanaja
- Vernon K Yong
- Vi Huyen Doan
- Victor H Yong
- Vira Wardhana Istiantoro
- Visanee Tantisevi
- Vital P Costa
- VJ Verhoeven
- Widya Artini Wiyogo
- Wing Lau Ho
- Xiao Yin Chen
- Xiao-Yu Ng
- Y Chen
- Y Lachkar
- Y Okada
- Ya-Xing Wang
- Yaakub Azhany
- Yaan Fun Chong
- Yasuo Kurimoto
- Yee Yee Aung
- Yi Xin Zeng
- Yik Y Teo
- Yin Mon Aung
- Yoko Ikeda
- Yong Ho Sohn
- Young Hoon Hwang
- YS Cho
- YS Kim
- Yuzhen Jiang
- Z Li
- Z Shen
- Zeiras Eka Djamal
- Zheng Li
- Zhicheng Xie
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
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- Alakaloko Felix
- Alaloul Enas
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- Alexandre Challine
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- Alghamdi Basim
- Alghamdi Masood
- Alghamdi Mohammed Saleh A.
- Algohary Osama
- Alhabli Ibrahim
- Alhady Khaled
- Alhassan Basmah
- Alhazmi Wedyan
- Alhendy Mohammed
- Alherz Mohammad
- Ali Ahmad
- Ali Ahmed
- Ali Ased
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Farah Mahmoud
- Ali Hussein
- Ali Safia
- Ali Samuel Sani
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Alihonou Thierry
- Alimi Quentin
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- Alkammash Abdelrahman
- Alkelani Muhammad
- Alkhabbaz Dalia
- Allam Meran
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- Allegri Andrea
- Allen John Lee Y
- Almallah Ahmad
- Almanon Christel Leanne
- Almoflihi Abdullah
- Almuallem Sultan
- Almy Jack
- Alnaby Mohamed Hassab
- Alnawam Ehab
- Alnuqaydan Saleh A.
- Alnusairat Aseel
- Alomar Ibrahim N.
- Alqahtani Enas
- Alqahtani Saleh
- Alrahawy Mahmoud
- Alrajraji Mawaddah
- Alrifaie Ahmad
- AlRowais Mohammed
- Alsaggaf Mohammed
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
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- Althwainy Amani
- Altibi Ahmed
- Altinel Yuksel
- Altoe Fernanda
- Altwigry Abdulrahman M.
- Altwijri Abdulaziz
- Alvarez Ismael Isaac Zelada
- Alvi Abdul Rehman
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- Aly Abouelatta Khairy
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- Alzahrani Mohammed
- Alzayat Thuraya
- Aman Nowrin F.
- Amandito Radhian
- Ambrozeviciute Viktorija
- Ameen Mohamed
- Amer Mohamed A
- Amin Hager Abdul Aziz
- Amin Jasim
- Amin Shadid Al
- Amjad Mohammadasim
- Ammar Mohamed
- Ammar Mohamed Sabry
- Amoah Michael
- Amoako Joachim
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- Assal Abdelrahman
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- Atkinson Kieran
- Atobatele Kazeem
- Attallah Noura A.
- Attar Samaa Mahmoud Al
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- Aziz Mohamed Rezal Abdul
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- Azizeldine Mohammed G.
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- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badr Ahmed
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin M
- Badwi Nermin Mohamed
- Badwy Assmaa
- Bahar Suraya
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- Bailey Karen
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- Balkan Ali Zeynel Abidin
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- Barrawi Fayez Elian Al
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- Barrios Emanuel
- Barrios Emmanuel
- Basilicò Silvia
- Basir Elissa Rifhan Mohd
- Bassem Monica
- Bassit Khalil Abdul
- Basso Celeste Del
- Basso Stefano M. M
- Bastawis Fatema Al
- Basto Carlos Alejandro Arroyo
- Bautista Ana Cecilia Manchego
- Beasley William
- Bedada Alemayehu Ginbo
- Bediako-Bowan Antoinette
- Behar Nebil
- Beisa Virgilijus
- Bekhet Amira Hassan
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- Beleño Alvaro Enrique Mendoza
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- Belli Andrea
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- Elsayed Makki
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- Elsayed Zaynab M
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- Niazi Ali Khan
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- null null
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- Shamsedine Ahmed W.
- Shamsi Ghina Shamim
- Sharpin Claire
- Shatkar Veereanna
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- Shawki Marwan
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- Shehata Sherif
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- Shiwani Haaris A.
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- Staerkle Ralph F
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- Thanusan Vimalakanthan
- Tharmalingam Shivanee
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- Thollot Aurore
- Thomas Efeson
- Thomas Hannah S
- Thompson Ben
- Thorarinsdottir Hildur
- Thorell Anders
- Thorsen Kenneth
- Ticona Willy Alcca
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- Tun Aung Kyaw
- Tun Myint
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- Turner Megan
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- Tyler Robert
- Tze R. Goh Ern
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- Ukwenya Yahaya
- Uluşahin Mehmet
- Upadhyaya Vijaid
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- Urniežius Zigmantas
- Urquizu Mario Contreras
- Usaityte Ausrine
- Uščinas Laimonas
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- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldaña María
- Valioulis Ioannis
- Vargas Marvin
- Varkalys Karolis
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Vega Gustavo Miguel Machain
- Velasquez Ricardo
- Velásquez Armando José Román
- Velásquez Carlos Iván Pérez
- Vella-Baldacchino Martinique
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venugopal Caranj
- Verjee Azmina
- Vermaas Maarten
- Veronese Ezio
- Vianna Julia Guasti Pinto
- Vicario Erika
- Vida Lucian Corneliu
- Vilčinskas Mantas
- Villa Roberta
- Villalobos Santiago
- Vimalachandran Dale
- Vincent Joe
- Violi Paola
- Višinskas Petras
- Vivekanantham Sayinthen
- Vlachogiorgos Apostolos
- Vollmer Sebastian
- Voulgaris Evangelos
- Wael Noha
- Wagener Mark
- Waleed Hamza
- Walędziak Maciej
- Walsh Michael
- Waqar Muhammad
- Warda Mahmoud
- Warren Oliver
- Waterman Ade
- Watts Anna
- Weber Beatrix
- Weber Per
- Weiser Thomas G
- Wheeler James
- Whitaker John
- White Timothy
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Wild Jonathan R L
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Witherspoon Paul
- Wogensen Fredrik
- Woin Evelina
- Wold Trude Beate
- Wolf Bernhard
- Wondimu Sahlu
- Wondoh Paul
- Wong Chee Siong
- Wong Chui Yee
- Wong Hong Yee
- Wood Greta
- Woodward Helen
- Worku Mengistu
- Worku Tewodros
- Wredberg Cecilia
- Wright Naomi J
- Xerri Thelma
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yaseen Tahir
- Yaseen Tahir Muhammad
- Yavuz Mehmet Ali
- Ye Joselyn
- Yeang Li Jing
- Yeo Lee Shi
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yip Chingwan
- Yip Sebastian Bernardo Shu
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yong Cheryl Ou
- Yong Guo Liang
- Youssef Daniel
- Youssef Haney
- Youssef Mohamed
- Youssif Jehad Hassan
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zachariades Dimitris-Christos
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zalabia Mohamed F
- Zamarin Kresimir
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zardab Ali
- Zegarra Sergio
- Zerihun Abebe Bekele
- Zhang Zhongtao
- Zheng Fei
- Zidan Hagar
- Zidan Mohamed
- Ziff Oliver
- Zil-E-Ali Ahsan
- Zohair Ahmed
- Zuber Markus
- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Mohamed
- Abbasy Jibran
- Abbo Olivier
- Abbouch Meryem
- Abd-Elmawla Manar
- Abd-Elrasoul Yasmin
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdel-Wahab Nehal Yosri Elsayed
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- AbdelFattah Ibrahim
- Abdelgelil Asmaa
- Abdelghany Sarah
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkareem Ahmed
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraheim Mohamed
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshafy Mahmoud
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulbagi Omar
- Abdulgawad Mahmoud
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abebe Nebiyou Seyoum
- Abebe Nebyou Seyoum
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboarab Aya
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboraya Metwally
- Aboraya Mohammad
- Abouelnasr Alaa
- Aboul-Naga Mariam Saad
- Abouzahra Amany
- Abouzaid Arwa
- Abozaid Mohamed
- Abozeid Khaled
- Abozyed Mahmoud Ahmed Fathi
- Abu-toyour Maram
- Abubakr Marwan
- Abudeeb Haytham
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abuseif Mohamed
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Nourhan
- Adams Ryan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adekoya Adeleke
- Adel Abdalrahman
- Adel Ahmed
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesuyi Abidemi
- Adeyeye Ademola
- Adham Walid
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adnan Ahmad Bin
- Adu-Aryee Niiarmah
- Afana Samah
- Afandy Ahmed
- Afifi Ahmed Mohamed
- Africa South
- Agalianos Christos
- Agarwal Arnav
- Agbedinu Kwabena
- Agius Marija
- Aglan Amro
- Aguilar Wendy Leslie Messa
- Aguilar-Jimenez Jose
- Aguilera Maria Lorena
- Aguilera Omar
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahmed Ahmed
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Emad Ali
- Ahmed Hala
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahmed Soliman Magdy
- Ahounou Ernest Yemalin Stephane
- Aigrain Yves
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi E
- Ajiboye Anthony
- Akatibo Emmanuel
- Akeel Nouf
- Akoto Elliot
- Al-Aarag Asmaa Abdel-Rahman
- Al-Azraqi Israa Abdullah Aziz
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-Faifi Jubran J
- Al-faqawi Maha
- Al-farram Hadeel
- Al-Hameedi Hasan Ismael Ibraheem
- Al-Hasani Ruqaya Kadhim Mohammed Jawad
- Al-khatib Ahmed
- Al-Mallah Abdullah
- Al-Marakby Dina
- Al-Mousa Mashael
- Al-Nahrawi Safwat
- Al-Obaedi Ossama
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-shammari Abeer
- Al-Slaibi Ibrahim
- Al-taher Taher
- Alada Muslimat
- Alahmady Omar
- Alakaloko Felix
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- Elgendy Fatimah I
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- Elnagar Ahmedglal
- Elnajjar Mahmoud A.
- Elnemr Abdelrhman Essam
- Elrazek Aly Abd
- Elsabbagh Nourhan
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- Elsawy Amira
- Elsayed Makki
- Elsayed Mohammed
- Elsayed Nada Ahmed Reda
- Elsayed Nadin
- Elsayed Zaynab M
- Elsebaaye Abdelrhman Osama
- Elsehimy Mohamed
- Elsemelawy Rofida
- Elshaar Mohammed
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- Elshafay Abd Elrahman
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- Elsorogy Diaa Eldin Abdelazeem Amin
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- Elwakil Hager
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- Elzahed Nada
- Elzayat Ibrahim
- Elzayat Mohamed
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- Emergencia Cirugia De
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- Fahmy Mohamed A Baky
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- Farag Ahmed
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- Farfan Erick Samuel Florez
- Farhad Mustafa
- Farhan-Alanie Muhamed M H
- Farinella Eriberto
- Farmakis Konstantinos
- Farouk Sara Amr Mohamed
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- Fermani Claudio
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- Halhouli Oday
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- null null
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- Shaalan Mohamed
- Shabkah Alaa
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- Zegarra Sergio
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- Zheng Fei
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- Zidan Mohamed
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- Zil-E-Ali Ahsan
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- Zulkifli Athirah
- Žilinskas Justas
- Žilinskienė Reda
- Žiubrytė Greta
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
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- Smith Albert J. Jr.
- Smith J
- Smith M. J.
- Smith M. J.
- So K.
- Soaba Russell
- Social Science
- Sociology
- Somlo Patty
- Sones Deborah G
- Song Cathy
- Soto Gary
- Spencer David
- Speraw S.
- Spoehr Alexander
- Sridhar Kamal K
- Stabile Jeff
- Staccy Jackie
- Stasiulus Daiva
- Steltzer Ulli
- Stem TWM
- Stenderup Viberke
- Stephan Cookie White
- Stokes Bruce
- Stolarik M. Mark
- Strnfa
- Strom Robert
- Stromquist Shelton
- Strouse Joan
- Studies Center
- Subramani
- Sue JenniferAbe
- Summers Molly
- Sunoo Brenda Paik
- Tabrah Ruth M
- Tainer Evelina
- Takagi Mariko
- Takaki JanieHitomi
- Takaki Ronald
- Takami David
- Takami David
- Tamura Linda
- Tan Amy
- Tarpley John
- Tatar Elizabeth
- Taverna Odette
- Teachers College
- Tepper M.
- The
- The Original Tracks Portland
- Thompson Richard H
- Tidwell Romeria
- Tien-Hyatt L.
- Tiffany Sharon W
- Tinloy Marion
- Tokyo
- Tollefson W.
- Tong Rosemarie
- Train Patricia A
- Trueba Henry T
- Tsang Daniel C
- Tsuang W.
- Tsui Alice M
- Tsui Kitty
- Tsui P.
- Tsukada Mamoru
- Tsutakawa Mayumi
- Tumarkin D. D.
- U.S. Commission
- Uamzon T. A.
- Ugalde-Yellen Corazon
- Umemoto Karen
- Unnithan N. Prabha.
- Urban Education
- Van Tran Thahn
- Vang Chue
- Vang Kou
- Vang Kou
- Vaughan Palani
- Villegas Jose J
- Vogt Lynn A
- Vue Pao Ly
- Wald Alan
- Walker Keith
- Ward W. Peter.
- Watts Jerry G
- Waugh Dexter
- Wegner Eldon L
- Weis Lois
- Weisner S.
- Weiss Michael J
- West
- White Hmong Language Lessons
- White Michael J
- Wilkinson
- Wilkinson D. Y.
- Will George M
- Willcox Don
- Williams
- Williams Carolyn L
- Wilson Anne
- Wilson R.
- Wilson-Smith April
- Winter F. H.
- Wong
- Wong Bernard
- Wong JadeSnow
- Wong William
- Wong-Rieger Durhane
- Woo Merle
- Wooden Wayne S
- Word David L
- Wu LiZhen
- Wurzel Jaime
- Xenos Peter
- Yamamoto Hisaye
- Yamamoto Joe
- Yamamoto Kathee
- Yao Esther Lee
- Yao Mary V
- Yasui Minoru
- Yee L. Y.
- Yellow Pages Japan Inc
- Yochum Gilbert
- Yoon K. K.
- Young Bear Ray
- Young P. K. Y.
- Yuen J.
- Zaharlick A.
- Zarsky Lyuba
- Zhang
- Zimmerman Diana
- Zoglin J.
- Publication venue
- 'UCLA American Indian Studies Center'
- Publication date
- Field of study