Recent Progress in the Golem Project

We report on the current status of the Golem project which aims at the construction of a general one-loop evaluator for matrix elements. We construct the one-loop matrix elements from Feynman diagrams in a highly automated way and provide a library for the reduction and numerically stable evaluation of the tensor integrals involved in this approach. Furthermore, we present applications to physics processes relevant for the LHC.Comment: 7 pages, 4 figures, contrib. to proceedings of "Loops and Legs in Quantum Field Theory", 10th DESY Workshop on Elementary Particle Theory, 25-30 April 2010, Woerlitz, German

Charmonium Composition and Nuclear Suppression

We study charmonium production in hadron-nucleus collisions through the intermediate next-to-leading Fock space component $|(\bar{c}c)_8 g>$, formed by a colour octet $\bar{c}c$ pair and a gluon. We estimate the size of this state and show that its interaction with nucleons accounts for the observed charmonium suppression in nuclear interactions.Comment: Plain TeX, 8 pages, 5 figures available upon reques

Dispelling the N^3 myth for the Kt jet-finder

At high-energy colliders, jets of hadrons are the observable counterparts of the perturbative concepts of quarks and gluons. Good procedures for identifying jets are central to experimental analyses and comparisons with theory. The Kt family of successive recombination jet finders has been widely advocated because of its conceptual simplicity and flexibility and its unique ability to approximately reconstruct the partonic branching sequence in an event. Until now however, it had been believed that for an ensemble of N particles the algorithmic complexity of the Kt jet finder scaled as N^3, a severe issue in the high multiplicity environments of LHC and heavy-ion colliders. We here show that the computationally complex part of Kt jet-clustering can be reduced to two-dimensional nearest neighbour location for a dynamic set of points. Borrowing techniques developed for this extensively studied problem in computational geometry, Kt jet-finding can then be performed in N ln N time. Code based on these ideas is found to run faster than all other jet finders in current use.Comment: 11 pages, 3 figures; v2, to appear in Phys.Lett.B, includes an extra section briefly discussing the issues of jet areas and pileup subtraction, and also the Cambridge/Aachen jet finde

Semi-numerical resummation of event shapes

For many event-shape observables, the most difficult part of a resummation in the Born limit is the analytical treatment of the observable's dependence on multiple emissions, which is required at single logarithmic accuracy. We present a general numerical method, suitable for a large class of event shapes, which allows the resummation specifically of these single logarithms. It is applied to the case of the thrust major and the oblateness, which have so far defied analytical resummation and to the two-jet rate in the Durham algorithm, for which only a subset of the single logs had up to now been calculated.Comment: 29 pages, 7 figures. Version 2 adds some clarifications, a reference, as well as corrections to the subleading fixed-order coefficients and to figures 4 and

Dilepton-tagged jets in relativistic nucleus-nucleus collisions: A case study

We study the A+B -> l+ l- + jet +X process in nucleus-nucleus collisions at relativistic energies. The dilepton as well as the jet will pass through the matter produced in such collisions. The recoiling dilepton will carry information about the kinematical features of the jet, and will thus prove to be a very effective tool in isolating in-medium effects such as energy-loss and fragmentation function modifications. We estimate the contributions due to correlated charm and bottom decay and we identify a window where they are small as compared to pairs from the NLO Drell-Yan process.Comment: 7 pages, 9 figures Two figures modified, references adde

A Repeated Measures Experiment of Green Exercise to Improve Self-Esteem in UK School Children

Exercising in natural, green environments creates greater improvements in adult's self-esteem than exercise undertaken in urban or indoor settings. No comparable data are available for children. The aim of this study was to determine whether so called 'green exercise' affected changes in self-esteem; enjoyment and perceived exertion in children differently to urban exercise. We assessed cardiorespiratory fitness (20 m shuttle-run) and self-reported physical activity (PAQ-A) in 11 and 12 year olds (n = 75). Each pupil completed two 1.5 mile timed runs, one in an urban and another in a rural environment. Trials were completed one week apart during scheduled physical education lessons allocated using a repeated measures design. Self-esteem was measured before and after each trial, ratings of perceived exertion (RPE) and enjoyment were assessed after completing each trial. We found a significant main effect (F (1,74), = 12.2, p<0.001), for the increase in self-esteem following exercise but there was no condition by exercise interaction (F (1,74), = 0.13, p = 0.72). There were no significant differences in perceived exertion or enjoyment between conditions. There was a negative correlation (r = -0.26, p = 0.04) between habitual physical activity and RPE during the control condition, which was not evident in the green exercise condition (r = -0.07, p = 0.55). Contrary to previous studies in adults, green exercise did not produce significantly greater increases in self-esteem than the urban exercise condition. Green exercise was enjoyed more equally by children with differing levels of habitual physical activity and has the potential to engage less active children in exercise. © 2013 Reed et al

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

CRISPR-based precise gene-editing requires simultaneous delivery of multiple components into living cells, rapidly exceeding the cargo capacity of traditional viral vector systems. This challenge represents a major roadblock to genome engineering applications. Here we exploit the unmatched heterologous DNA cargo capacity of baculovirus to resolve this bottleneck in human cells. By encoding Cas9, sgRNA and Donor DNAs on a single, rapidly assembled baculoviral vector, we achieve with up to 30% efficacy whole-exon replacement in the intronic β-actin (ACTB) locus, including site-specific docking of very large DNA payloads. We use our approach to rescue wild-type podocin expression in steroid-resistant nephrotic syndrome (SRNS) patient derived podocytes. We demonstrate single baculovirus vectored delivery of single and multiplexed prime-editing toolkits, achieving up to 100% cleavage-free DNA search-and-replace interventions without detectable indels. Taken together, we provide a versatile delivery platform for single base to multi-gene level genome interventions, addressing the currently unmet need for a powerful delivery system accommodating current and future CRISPR technologies without the burden of limited cargo capacity

Resummed event-shape variables in DIS

We complete our study of resummed event-shape distributions in DIS by presenting results for the class of observables that includes the current jet mass, the C-parameter and the thrust with respect to the current-hemisphere thrust axis. We then compare our results to data for all observables for which data exist, fitting for alpha_s and testing the universality of non-perturbative 1/Q effects. A number of technical issues arise, including the extension of the concept of non-globalness to the case of discontinuous globalness; singularities and non-convergence of distributions other than in the Born limit; methods to speed up fixed-order Monte Carlo programs by up to an order of magnitude, relevant when dealing with many x and Q points; and the estimation of uncertainties on the predictions.Comment: 41 page

Vector boson production at hadron colliders: hard-collinear coefficients at the NNLO

We consider QCD radiative corrections to vector-boson production in hadron collisions. We present the next-to-next-to-leading order (NNLO) result of the hard-collinear coefficient function for the all-order resummation of logarithmically-enhanced contributions at small transverse momenta. The coefficient function controls NNLO contributions in resummed calculations at full next-to-next-to-leading logarithmic accuracy. The same coefficient function is used in applications of the subtraction method to perform fully-exclusive perturbative calculations up to NNLO.Comment: 13, pages, no figures. arXiv admin note: text overlap with arXiv:1106.465