Ion-Sensitive Field-Effect Transistor for Biological Sensing

In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells

Bio FEDs (field-effect-devices): "State-of-the-art and new directions

This paper gives a brief survey on biologically sensitive FEDs (field-effect devices) and introduces some recent approaches in this field. Basic concepts, functional principles and current trends in research and development for namely, ISFETs (ion-sensitive field-effect transistors), capacitive EIS (electrolyte-insulator-semiconductor) sensors and LAPS (light-addressable potentiometric sensor) structures will be presented