Controlled stacking of graphene monolayer saturable absorbers for ultrashort pulse generation in erbium-doped fiber lasers

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPStacked chemical-vapour deposited (CVD) graphene monolayer samples were fabricated and applied as saturable absorbers in erbium-doped fiber laser (EDFL). Transient absorption experiments show that at the saturation absorption regime, and regardless the number of stacked layers (from 1 to 5 layers), samples present 1 ps recovery time. Pulses with duration from 0.60 to 1.17 ps were generated in an EDFL, depending on the number of graphene layers (i.e., the linear optical absorption) used. The results show that it is possible to increase the linear optical absorption of a graphene stacking without affecting its nonlinear optical behavior and ultrafast response time. Therefore, by stacking individual CVDmonolayer graphene samples it is possible to control the optical properties in graphene-based EDFLs and simultaneously tune their ultra-short pulse generation.7725282537FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP2010/19085-82012/07678-02012/50259-82013/16911-

Atributos físicos e biológicos de um Neossolo Flúvico sob diferentes sistemas de manejo cultivado com feijão-caupi.

O objetivo deste trabalho foi avaliar as alterações ocorridas nos atributos físicos e biológicos de um Neossolo Flúvico, em sistemas de plantio convencional e direto, cultivado com feijão-caupi

Chemical composition, antifungal activity and potential anti-virulence evaluation of the Eugenia uniflora essential oil against Candida spp.

Made available in DSpace on 2018-06-07T01:06:27Z (GMT). No. of bitstreams: 1 ART18022.pdf: 2573576 bytes, checksum: 0dcd8f7123a9ebba1c1ac9e8f328b113 (MD5) Previous issue date: 2018-06-04bitstream/item/178269/1/ART18022.pd

The role of bioenergy in a climate-changing world

Bioenergy has been under intense scrutiny over the last ten years with significant research efforts in many countries taking place to define and measure sustainable practices. We describe here the main challenges and policy issues and provide policy recommendations for scaling up sustainable bioenergy approaches globally. The 2016 Intended Nationally Determined Contributions (INDCs defined under the UN Framework Convention on Climate Change) (UNFCCC) Conference of the Parties (COP21) will not reach global Greenhouse Gas (GHG) emission targets of 2°C. Sustainable biomass production can make a significant contribution. Substantive evidence exists that many bioenergy cropping systems can bring multiple benefits and off-set environmental problems associated with fossil fuels usage as well as intensive food production and urbanization. We provide evidence that there are many approaches to land use for bioenergy expansion that do not lead to competition for food or other needs. We should focus on how to manage these approaches on a synergistic basis and how to reduce tradeoffs at landscape scales. Priorities include successful synergies between bioenergy and food security (integrated resource management designed to improve both food security and access to bioenergy), investments in technology, rural extension, and innovations that build capacity and infrastructure, promotion of stable prices to incentivize local production and use of double cropping and flex crops (plants grown for both food and non-food markets) that provide food and energy as well as other services. The sustainable production of biomass requires appropriate policies to secure long-term support to improve crop productivity and also to ensure environmental as well as economic and social benefits of bioenergy cropping systems. Continuous support for cropping, infrastructure, agricultural management and related policies is needed to foster positive synergies between food crops and bioenergy production. In comparison to fossil fuels, biofuels have many positive environmental benefits. Potential negative effects caused by land-use change and agriculture intensification can be mitigated by agroecological zoning, best management practices, the use of eco-hydrology and biodiversity-friendly concepts at field, watershed and landscape scales. Global climate and environmental changes related to the use of fossil fuels and inequitable development make it unethical not to pursue more equitable energy development that includes bioenergy. To achieve sustainable development, competitiveness and costs of bioenergy production need to be addressed in a manner that considers not only economic gains but also development of local knowledge and social and environmental benefits

Coupled dark energy: Towards a general description of the dynamics

In dark energy models of scalar-field coupled to a barotropic perfect fluid, the existence of cosmological scaling solutions restricts the Lagrangian of the field \vp to p=X g(Xe^{\lambda \vp}), where X=-g^{\mu\nu} \partial_\mu \vp \partial_\nu \vp /2, $\lambda$ is a constant and $g$ is an arbitrary function. We derive general evolution equations in an autonomous form for this Lagrangian and investigate the stability of fixed points for several different dark energy models--(i) ordinary (phantom) field, (ii) dilatonic ghost condensate, and (iii) (phantom) tachyon. We find the existence of scalar-field dominant fixed points (\Omega_\vp=1) with an accelerated expansion in all models irrespective of the presence of the coupling $Q$ between dark energy and dark matter. These fixed points are always classically stable for a phantom field, implying that the universe is eventually dominated by the energy density of a scalar field if phantom is responsible for dark energy. When the equation of state w_\vp for the field \vp is larger than -1, we find that scaling solutions are stable if the scalar-field dominant solution is unstable, and vice versa. Therefore in this case the final attractor is either a scaling solution with constant \Omega_\vp satisfying 0<\Omega_\vp<1 or a scalar-field dominant solution with \Omega_\vp=1.Comment: 21 pages, 5 figures; minor clarifications added, typos corrected and references updated; final version to appear in JCA

Search for New Physics with Jets and Missing Transverse Momentum in pp collisions at sqrt(s) = 7 TeV

A search for new physics is presented based on an event signature of at least three jets accompanied by large missing transverse momentum, using a data sample corresponding to an integrated luminosity of 36 inverse picobarns collected in proton--proton collisions at sqrt(s)=7 TeV with the CMS detector at the LHC. No excess of events is observed above the expected standard model backgrounds, which are all estimated from the data. Exclusion limits are presented for the constrained minimal supersymmetric extension of the standard model. Cross section limits are also presented using simplified models with new particles decaying to an undetected particle and one or two jets

Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study

We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout period, after which they were randomly divided into 5 groups that received daily a placebo, a capsule containing one of the 3 strains or a capsule containing a mixture of two strains for 30 days. The intervention was followed by another 15-day washout period. Patients did not consume fermented milk for the entire duration of the study. Gastrointestinal symptoms, defecation frequency and stool consistency were not altered by probiotic intake. No relevant changes in blood and serum, as well as no adverse events occurred during or after treatment. Probiotic administration slightly modified bacterial populations in the volunteers’ feces. Intestinal persistence occurred in volunteers who received L. rhamnosus CNCM I-4036. Administration of B. breve CNCM I-4035 resulted in a significant increase in fecal secretory IgA content. IL-4 and IL-10 increased, whereas IL-12 decreased in the serum of volunteers treated with any of the three strains. These results demonstrate that the consumption of these three bacterial strains was safe and exerted varying degrees of immunomodulatory effects.Part of the research currently in progress in the authors' laboratory is funded by the company Hero Spain, S. A. through the grant #3582 managed by the Fundacion General Empresa-Universidad de Granada

Deltamethrin Resistance Mechanisms in Aedes aegypti Populations from Three French Overseas Territories Worldwide

BACKGROUND:Aedes aegypti is a cosmopolite mosquito, vector of arboviruses. The worldwide studies of its insecticide resistance have demonstrated a strong loss of susceptibility to pyrethroids, the major class of insecticide used for vector control. French overseas territories such as French Guiana (South America), Guadeloupe islands (Lesser Antilles) as well as New Caledonia (Pacific Ocean), have encountered such resistance. METHODOLOGY/PRINCIPAL FINDINGS:We initiated a research program on the pyrethroid resistance in French Guiana, Guadeloupe and New Caledonia. Aedes aegypti populations were tested for their deltamethrin resistance level then screened by an improved microarray developed to specifically study metabolic resistance mechanisms. Cytochrome P450 genes were implicated in conferring resistance. CYP6BB2, CYP6M11, CYP6N12, CYP9J9, CYP9J10 and CCE3 genes were upregulated in the resistant populations and were common to other populations at a regional scale. The implication of these genes in resistance phenomenon is therefore strongly suggested. Other genes from detoxification pathways were also differentially regulated. Screening for target site mutations on the voltage-gated sodium channel gene demonstrated the presence of I1016 and C1534. CONCLUSION /SIGNIFICANCE:This study highlighted the presence of a common set of differentially up-regulated detoxifying genes, mainly cytochrome P450 genes in all three populations. GUA and GUY populations shared a higher number of those genes compared to CAL. Two kdr mutations well known to be associated to pyrethroid resistance were also detected in those two populations but not in CAL. Different selective pressures and genetic backgrounds can explain such differences. These results are also compared with those obtained from other parts of the world and are discussed in the context of integrative research on vector competence

LC-MS analysis and antifungal activity of Turnera subulata Sm.

Fungi of the Candida genus are responsible for invasive candidiasis, which affects people all over the world and has high mortality rates. This is due to their virulence factors, which give them great resistance and pathogenicity. In addition, the emergence of multidrug-resistant strains makes it difficult to treat these infections. In this way, natural products have emerged as an alternative to standard drugs, where plants known for their medicinal properties such as Turnera subulata become attractive to research. The present work aimed to analyze the ethanol extract of Turnera subulata leaves against standard strains of Candida albicans, Candida krusei and Candida tropicalis using broth microdilution techniques. The identification of the compounds in T. subulata leaves by LC-MS revealed the presence of a wide variety of substances such as carboxylic acids and terpenes, with flavonoids and fatty acids being more evident. The antifungal assays showed that the extract was not able to inhibit the growth of the tested strains at concentrations with a clinical relevance. However, at higher concentrations, it was able to inhibit the fungal dimorphism of C. albicans and C. tropicalis. It is possible that the T. subulata extract has potential as an inhibitor of fungal virulence factors without affecting the cell viability. Further research should be carried out in order to assess its inhibitory potential for other fungal virulence factors