Effect of Gypsum and Polyacrylamides on Water Turbidity and Infiltration in a Sodic Soil

Water ponded on sodic soils can develop turbidity problems which seriously affect rice crop establishment. A total of 19 polyacrylamide products were tested to assess their effectiveness to control water turbidity in a sodic soil under laboratory conditions. Anionic polyacrylamides were more effective than cationic or non-ionic polyacrylamides. When combined with gypsum, polyacrylamides were found to be more effective than applied alone. A split application strategy was more efficient than continuous application of polyacrylamide treatments. Different rates of polyacrylamides at 2.5, 5 and 10 kg/ha did not show significant difference in controlling water turbidity. Selected polyacrylamides were also tested on soil columns to study their effect on infiltration and percolation of water through the soil. Results have shown that polyacrylamides combined with low rates of gypsum did not modify the infiltration pattern to a greater extent. This study demonstrated that anionic polyacrylamides applied with small quantities of gypsum through a split application strategy would be an appropriate technique to overcome water turbidity problems in sodic soils

Dexamethasone Suppresses Histamine Synthesis by Repressing both Transcription and Activity of HDC in Allergic Rats

ABSTRACTBackgroundHistamine synthesized by histidine decarboxylase (HDC) from L-histidine is a major chemical mediator in the development of nasal allergy which is characterized by nasal hypersensitivity. However the regulatory mechanism of histamine synthesis by HDC remains to be elucidated. The objectives of the present study were to examine the changes of histamine content, HDC activity and HDC mRNA expression in the nasal mucosa of allergy model rats sensitized by the exposure to toluene diisocyanate (TDI) and to investigate the effect of dexamethasone on the above mentioned allergic parameters.MethodsRats were sensitized and provocated by TDI and the nasal allergy-like behaviors were scored during a 10 minute period after provocation. Histamine content and HDC activity in the nasal mucosa were determined using fluorometric high performance liquid chromatography. The expression of HDC mRNA in nasal mucosa was determined using real-time quantitative reverse transcriptase-polymerase chain reaction (RT-PCR).ResultsIn TDI-sensitized rats, nasal allergy-like behaviors such as sneezing and watery rhinorrhea were induced. Histamine content, HDC activity and HDC mRNA expression in nasal mucosa were also significantly increased after TDI provocation. Pretreatment with dexamethasone significantly suppressed nasal allergy-like behaviors, up-regulation of histamine content, HDC activity and HDC mRNA induced by TDI in TDI-sensitized rats.ConclusionsThese findings indicate that increased synthesis of histamine through up-regulation of HDC gene expression and HDC activity in nasal mucosa plays an important role in the development of nasal hypersensitivity. Repression of HDC gene expression and HDC activity by dexamethasone may underlie its therapeutic effect in the treatment of allergy