Hygienic substantiation off criteria of expansion of the prenatal monitoring programme under conditions of the impact of industrial chemical factors(bv the example of Perm region)

The authors aimed to hygienically substantiate the criteria of expansion of the programme of prenatal monitoring of congenital malformations in fetation taking into account territorial environmental load. The investigation was carried out by the example of the town of Berezniki that is the centre of the chemical industry in Perm Region. The subjects of the study were pregnant women, parturient women and newborns, programmes of prenatal diagnostics of congenital malformations. The blood of pregnant women from a risk group contained a number of organic compounds and heavy metals (benzene, toluene, ethylbenzene, phenol, manganese, lead, vanadium); their increased concentrations have a significant adverse impact in the form of a risk of increased levels of congenital malformations’ seromarkers during fetation. The paper indicates and recommends regional maximum permissible levels of blood toxicant concentrations in mothers and newborns. The article suggests a probability scale of individual nsk prediction of birth of children with congenital malformations. The authors present the prenatal monitoring programme taking into account territorial industrial load. Conclusions. Toxicant load of a pregnant woman’s organism is a significant risk factor for the development of congenital pathologies in children. The efficiency of the prenatal monitoring system may be increased by means of expanding and providing profound examinations of women from a high risk group in accordance with the regional specificity.Целью настоящего исследования являлось гигиеническое обоснование критериев расширения программы пренатального мониторинга врожденных пороков развития плода с учетом территориальной внешнесредовой нагрузки. Исследования выполнены на примере г. Березники, являющегося центром химической индустрии в Пермском крае. Объектом исследования являлись беременные женщины, роженицы и новорожденные дети, программы пренатальной диагностики врожденных пороков развития. В крови беременных женщин группы риска идентифицирован ряд органических соединений и тяжелых металлов (бензол, толуол, этилбензол, фенол, марганец, свинец, ванадий), увеличение концентрации которых оказывает значимое негативное влияние в виде риска повышения уровней сывороточных маркеров пороков развития плода. Определены и рекомендованы региональные предельно-допустимые уровни содержание токсикантов в крови матери и новорожденного. Предложена вероятностная шкала индивидуального прогноза риска рождения детей с врожденными деформациями развития. Представлена программа пренатального мониторинга с учетом территориальной техногенной нагрузки. Основные выводы. Токсикантная нагрузка организма беременной женщины является существенным фактором риска формирования врожденной патологии у детей. Эффективность системы пренатального мониторинга может быть повышена за счет расширения и углубления исследований женщин группы высокого риска в соответствии с региональной спецификой

Depth-psychological factors of dysthymic individuals’ abnormal interpersonal attitudes

The purpose of research was to study destructive and deficiency person’s factors of patients with dysthymia. There were investigated 50 patients (basic group) and 50 healthy subjects (control group). We used clinical-psychopathological (Symptom Checklist-90-Revised), experimental-psychological (ISTA Questionnaire, Buss&Durkee Aggression Questionnaire), statistical (descriptive statistics, Mann-Whitney U test) methods. It was estimated that unconscious central ego-functions of patients with dysthymia get expressed destructive or deficiency character. Low aggression and comparatively high level of animosity are peculiar to the patients with dysthymia. Patients with dysthymia are characterized by emotional stand-off, distrust to somebody, self-doubt as a result of insufficiently advanced ability of self-identification, inability to develop representations about own person, insufficiently flexible regulation of inherent activity, which is necessary for integration of mental life- on the one part, and expressed insult and suspiciousness - on the other part. This psychological peculiarity is supported with not adaptive patterns of behavior in the conditions of interpersonal relations and result in socio-psychological disadaptation.С целью оценки влияния глубинно-психологических факторов на сферу межличностных отношений у больных дистимией обследовано 50 пациентов (экспериментальная группа) и 50 здоровых лиц (группа сравнения). Методы: клинико-психопатологический (опросник SCL-90-R), экспериментально-психологический (опросник ISTA, опросник Басса-Дарки, опросник Бочарова), статистический (критерий U -Манна-Уитни, корреляционный и дисперсионный анализы). Установлено: у больных с дистимией бессознательные центральные Я-функции приобретают выраженный деструктивный или дефицитарный характер. Им свойственны низкая агрессивность и относительно высокий уровень враждебности. Отмечаются эмоциональная закрытость, недоверие к окружающ им, неуверенность в себе вследствие недостаточно развитой способности самоидентификации, способности развивать представления о собственной личности, недостаточно гибкой регуляции собственной активности, необходимой для интеграции психической жизни, - с одной стороны, и выраженной обиды и подозрительности - с другой. Эти психологические особенности не только приводят к социально-психологической дезадаптации, но и подкрепляются неадаптивными паттернами поведения в условиях межличностных отношений

Feasibility studies for the measurement of time-like proton electromagnetic form factors from p¯ p→ μ+μ- at P ¯ ANDA at FAIR

This paper reports on Monte Carlo simulation results for future measurements of the moduli of time-like proton electromagnetic form factors, | GE| and | GM| , using the p¯ p→ μ+μ- reaction at P ¯ ANDA (FAIR). The electromagnetic form factors are fundamental quantities parameterizing the electric and magnetic structure of hadrons. This work estimates the statistical and total accuracy with which the form factors can be measured at P ¯ ANDA , using an analysis of simulated data within the PandaRoot software framework. The most crucial background channel is p¯ p→ π+π-, due to the very similar behavior of muons and pions in the detector. The suppression factors are evaluated for this and all other relevant background channels at different values of antiproton beam momentum. The signal/background separation is based on a multivariate analysis, using the Boosted Decision Trees method. An expected background subtraction is included in this study, based on realistic angular distributions of the background contribution. Systematic uncertainties are considered and the relative total uncertainties of the form factor measurements are presented

PANDA Phase One - PANDA collaboration

The Facility for Antiproton and Ion Research (FAIR) in Darmstadt, Germany, provides unique possibilities for a new generation of hadron-, nuclear- and atomic physics experiments. The future antiProton ANnihilations at DArmstadt (PANDA or P¯ANDA) experiment at FAIR will offer a broad physics programme, covering different aspects of the strong interaction. Understanding the latter in the non-perturbative regime remains one of the greatest challenges in contemporary physics. The antiproton–nucleon interaction studied with PANDA provides crucial tests in this area. Furthermore, the high-intensity, low-energy domain of PANDA allows for searches for physics beyond the Standard Model, e.g. through high precision symmetry tests. This paper takes into account a staged approach for the detector setup and for the delivered luminosity from the accelerator. The available detector setup at the time of the delivery of the first antiproton beams in the HESR storage ring is referred to as the Phase One setup. The physics programme that is achievable during Phase One is outlined in this paper

Precision resonance energy scans with the PANDA experiment at FAIR: Sensitivity study for width and line shape measurements of the X(3872)

This paper summarises a comprehensive Monte Carlo simulation study for precision resonance energy scan measurements. Apart from the proof of principle for natural width and line shape measurements of very narrow resonances with PANDA, the achievable sensitivities are quantified for the concrete example of the charmonium-like X(3872) state discussed to be exotic, and for a larger parameter space of various assumed signal cross-sections, input widths and luminosity combinations. PANDA is the only experiment that will be able to perform precision resonance energy scans of such narrow states with quantum numbers of spin and parities that differ from J P C = 1 - -

Comparison of Distributions of Atmospheric Gas Admixture Concentrations Measured by Remote and In Situ Instruments over the Russian Sector of the Arctic

International audienc

Air Composition over the Russian Arctic: 1—Methane

In the Arctic, global warming is 2–3 times faster than over other regions of the globe. As a result, noticeable changes are already being recorded in all areas of the environment. However, there is very little data on such changes in the Russian Arctic. Therefore, to fill the gap in the data on the vertical distribution of the gas and aerosol composition of air in this region, an experiment was carried out on the Tu-134 Optik flying laboratory in September 2020 to sound the atmosphere and water surface over the water areas of all seas in the Russian Arctic. This paper analyzes the spatial distribution of methane. It is shown that during the experiment its concentration was the highest over the Kara Sea (2090 ppb) and the lowest over the Chukchi Sea (2005 ppb). The East Siberian and Bering Seas were slightly different from the Chukchi Sea in terms of the methane concentration. Average values of CH4 are characteristic of the Barents (2030 ppb) and the Laptev Seas (2040 ppb). The difference between the concentrations at an altitude of 200 meters and in the free troposphere attained 150 ppb over the Kara Sea, decreased to 91 and 94 ppb over the Barents and Laptev Seas, and further decreased over the East Siberian, Chukchi, and Bering Seas to 66, 63, and 74 ppb, respectively. Horizontal heterogeneity in the distribution of methane over the Arctic seas is the greatest over the Laptev Sea, where it attained 73 ppb. It is two times higher than over the Barents and Kara Seas, and 5–7 times higher than over the East Siberian and Bering Seas

Air Composition over the Russian Arctic: 2–Carbon Dioxide

International audienceWe analyze the spatial distribution of carbon dioxide over the seas of the Russian Arctic based on the results of the comprehensive experiment conducted in September 2020. It turned out that during the experiment, the concentration of CO2 increased from west to east. The minimum of 396 ppm was over the Barents Sea, and the maximum of 4106 ppm was over the Chukchi Sea. The difference between the concentrations at an altitude of 200 m and in the free troposphere attained 156 ppm over the Barents Sea and decreased to 56 ppm over the Laptev Sea. Over the eastern seas, the difference became generally positive, which was associated with the air transfer from Alaska. Above the waters of most seas, the distribution of carbon dioxide was horizontally heterogeneous, which showed the regional features of its assimilation by the ocean and transfer from the continent