26 research outputs found

    Collaborative Action Learning and Leadership: A Feminist/Indigenous Model for Higher Education

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    An article discussion the intersectionality of feminism, traditional Indigenous models of leadership, and modern leadership studies

    Senior Recital: Jonathan Fallin, trumpet

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Music Education. Mr. Fallin studies trumpet with Dr. Douglas Lindsey.https://digitalcommons.kennesaw.edu/musicprograms/1026/thumbnail.jp

    Senior Recital: Connor Osburn, horn

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    This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Mr. Connor studies horn with Tom Witte.https://digitalcommons.kennesaw.edu/musicprograms/1257/thumbnail.jp

    2016-17 Concerto Competition Final Round

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    The 2016-17 Concerto Competition culminates in this performance featuring students competing to perform as a featured soloist with the KSU Symphony Orchestra on April 26, 2017.https://digitalcommons.kennesaw.edu/musicprograms/1695/thumbnail.jp

    A large-scale genome-wide association study meta-analysis of cannabis use disorder

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    Summary Background Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50–70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the study was to conduct a large genome-wide association study (GWAS) to identify novel genetic variants associated with cannabis use disorder. Methods To conduct this GWAS meta-analysis of cannabis use disorder and identify associations with genetic loci, we used samples from the Psychiatric Genomics Consortium Substance Use Disorders working group, iPSYCH, and deCODE (20 916 case samples, 363 116 control samples in total), contrasting cannabis use disorder cases with controls. To examine the genetic overlap between cannabis use disorder and 22 traits of interest (chosen because of previously published phenotypic correlations [eg, psychiatric disorders] or hypothesised associations [eg, chronotype] with cannabis use disorder), we used linkage disequilibrium score regression to calculate genetic correlations. Findings We identified two genome-wide significant loci: a novel chromosome 7 locus (FOXP2, lead single-nucleotide polymorphism [SNP] rs7783012; odds ratio [OR] 1·11, 95% CI 1·07–1·15, p=1·84 × 10−9) and the previously identified chromosome 8 locus (near CHRNA2 and EPHX2, lead SNP rs4732724; OR 0·89, 95% CI 0·86–0·93, p=6·46 × 10−9). Cannabis use disorder and cannabis use were genetically correlated (rg 0·50, p=1·50 × 10−21), but they showed significantly different genetic correlations with 12 of the 22 traits we tested, suggesting at least partially different genetic underpinnings of cannabis use and cannabis use disorder. Cannabis use disorder was positively genetically correlated with other psychopathology, including ADHD, major depression, and schizophrenia. Interpretation These findings support the theory that cannabis use disorder has shared genetic liability with other psychopathology, and there is a distinction between genetic liability to cannabis use and cannabis use disorder. Funding National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institute on Drug Abuse; Center for Genomics and Personalized Medicine and the Centre for Integrative Sequencing; The European Commission, Horizon 2020; National Institute of Child Health and Human Development; Health Research Council of New Zealand; National Institute on Aging; Wellcome Trust Case Control Consortium; UK Research and Innovation Medical Research Council (UKRI MRC); The Brain & Behavior Research Foundation; National Institute on Deafness and Other Communication Disorders; Substance Abuse and Mental Health Services Administration (SAMHSA); National Institute of Biomedical Imaging and Bioengineering; National Health and Medical Research Council (NHMRC) Australia; Tobacco-Related Disease Research Program of the University of California; Families for Borderline Personality Disorder Research (Beth and Rob Elliott) 2018 NARSAD Young Investigator Grant; The National Child Health Research Foundation (Cure Kids); The Canterbury Medical Research Foundation; The New Zealand Lottery Grants Board; The University of Otago; The Carney Centre for Pharmacogenomics; The James Hume Bequest Fund; National Institutes of Health: Genes, Environment and Health Initiative; National Institutes of Health; National Cancer Institute; The William T Grant Foundation; Australian Research Council; The Virginia Tobacco Settlement Foundation; The VISN 1 and VISN 4 Mental Illness Research, Education, and Clinical Centers of the US Department of Veterans Affairs; The 5th Framework Programme (FP-5) GenomEUtwin Project; The Lundbeck Foundation; NIH-funded Shared Instrumentation Grant S10RR025141; Clinical Translational Sciences Award grants; National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences.Peer reviewe

    Shared genetic risk between eating disorder- and substance-use-related phenotypes:Evidence from genome-wide association studies

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    First published: 16 February 202

    Frequently asked questions about chlorophyll fluorescence, the sequel

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    [EN] Using chlorophyll (Chl) a fluorescence many aspects of the photosynthetic apparatus can be studied, both in vitro and, noninvasively, in vivo. Complementary techniques can help to interpret changes in the Chl a fluorescence kinetics. Kalaji et al. (Photosynth Res 122: 121-158, 2014a) addressed several questions about instruments, methods and applications based on Chl a fluorescence. Here, additionalChl a fluorescence-related topics are discussed again in a question and answer format. Examples are the effect of connectivity on photochemical quenching, the correction of F-V/F-M values for PSI fluorescence, the energy partitioning concept, the interpretation of the complementary area, probing the donor side of PSII, the assignment of bands of 77 K fluorescence emission spectra to fluorescence emitters, the relationship between prompt and delayed fluorescence, potential problems when sampling tree canopies, the use of fluorescence parameters in QTL studies, the use of Chl a fluorescence in biosensor applications and the application of neural network approaches for the analysis of fluorescence measurements. The answers draw on knowledge fromdifferent Chl a fluorescence analysis domains, yielding in several cases new insights.Kalaji, H.; Schansker, G.; Brestic, M.; Bussotti, F.; Calatayud, A.; Ferroni, L.; Goltsev, V.... (2017). Frequently asked questions about chlorophyll fluorescence, the sequel. 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    Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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    Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and characterize the relationship between AD and other psychiatric and behavioral outcomes, we carried out the largest genome-wide association study to date of DSM-IV-diagnosed AD. Genome-wide data on 14,904 individuals with AD and 37,944 controls from 28 case-control and family-based studies were meta-analyzed, stratified by genetic ancestry (European, n = 46,568; African, n = 6,280). Independent, genome-wide significant effects of different ADH1B variants were identified in European (rs1229984; P = 9.8 x 10(-13)) and African ancestries (rs2066702; P = 2.2 x 10(-9)). Significant genetic correlations were observed with 17 phenotypes, including schizophrenia, attention deficit-hyperactivity disorder, depression, and use of cigarettes and cannabis. The genetic underpinnings of AD only partially overlap with those for alcohol consumption, underscoring the genetic distinction between pathological and nonpathological drinking behaviors.Peer reviewe

    An Indigenous Perspective on Women Leadership: An Example for Higher Education

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    Fielding Graduate University, founded in 1974, offers distributed graduate education and research programsin three social science areas: psychology, human and organizational development, and educationalleadership. All three schools affirm a commitment to social change and social justice. The EducationalLeadership and Change (ELC) doctoral program was developed in 1996 as a way to influence educationalreform and to make doctoral education accessible to working adults, especially those from underservedcommunities. During its development, the program struggled and faltered as it tried to establish its identityand work toward its goals. After an abrupt change in leadership, two women emerged to form a co-deanleadership team: Susan Tiara, Ph.D. and Judy Witt, Ph.D. Looking for a model that emphasized relationshipsand a more global outlook, they adopted Total Transformational Management Process (Mink, Esterhuysen,Mink, & Owen, 1993) as the conceptual framework for ELC's governance. Based on action researchprocesses, TTMP utilizes an inclusive model for change that emphasizes the system, "paying specialattention to the human side" (p. 11). TTMP was instrumental in developing ELC's way of simultaneouslyworking at the individual, group, and organizational levels and in seeing participatory action research (Park,1992, 1993) as "transformation concomitant with intense learning" (Mink, et al., 1993, p. 11). Consideringthe complexity of Fielding's dispersed learning environment, such a transformational priority in leadership,communication, and decision-making became a critical priority for both Fielding and EL
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