A Mixed Methods Approach to Identifying Administration Issues Pertinent in Interscholastic Sports

The purpose of this study was to investigate three propositions: a) What are the administration issues most pertinent to interscholastic sport today, as well as the next five years?, b) How important are those administration issues to athletic administrators?, and c) What are the potential implications of those pertinent administration issues to practicing athletic administrators? The literature provides a general overview of relevant issues surrounding interscholastic athletics. However, the importance and implications of relevant issues to practicing high school athletic administrators are difficult to discern. To answer the first proposition, the Minnesota State High School League (MSHSL) provided 10 contemporary administration issues that were most pertinent to interscholastic sport today, as well as the next five years. To answer the second proposition, a Likert-Scale was created so that practicing athletic administrators could rate each issue on a scale of 5 = extremely important to 1 = very little importance. A national study was conducted with athletic directors from the National Interscholastic Athletic Administrators Association (N = 170) annual conference. A one-tailed ANOVA was executed to determine significant differences among the 10 administration issues identified by the MSHSL. Four issues were found to be significant; Athletic Facilities, Athletic Training, Health Issues and Travel Teams. A Games-Howell post hoc was executed to determine significant differences across geographical regions of the United States. For the third proposition, semi-structured interviews were completed to provide insight on the implications for practicing athletic administrators. The results offer insight from which further investigations could be conducted to continue building on policies that influence interscholastic athletic administrators’ day-to-day accountability when overseeing their athletic programs

Millisecond Pulsars: Detectable Sources of Continuous Gravitational Waves?

Laboratory searches for the detection of gravitational waves have focused on the detection of burst signals emitted during a supernova explosion, but have not resulted in any confirmed detections. An alternative approach has been to search for continuous wave (CW) gravitational radiation from the Crab pulsar. In this paper, we examine the possibility of detecting CW gravitational radiation from pulsars and show that nearby millisecond pulsars are generally much better candidates. We show that the minimum strain h_c ~ 10E-26 that can be detected by tuning an antenna to the frequency of the milli- second pulsar PSR 1957+20, with presently available detector technology, is orders of magnitude better than what has been accomplished so far by observing the Crab pulsar, and within an order of magnitude of the maximum strain that may be produced by it. In addition, we point out that there is likely to be a population of rapidly rotating neutron stars (not necessarily radio pulsars) in the solar neighborhood whose spindown evolution is driven by gravitational radiation. We argue that the projected sensitivity of modern resonant detectors is sufficient to detect the subset of this population that lies within 0.1 kpc of the sun.Comment: 17 pages (including 2 Postscript figures), LaTeX file, uses AASTeX macros, accepted for publication in the Astrophysical Journa

Universal screening of Tanzanian HIV-infected adult inpatients with the serum cryptococcal antigen to improve diagnosis and reduce mortality: an operational study

Cryptococcal meningitis is a leading cause of death among HIV-infected individuals in sub-Saharan Africa. Recent developments include the availability of intravenous fluconazole, cryptococcal antigen assays and new data to support fluconazole pre-emptive treatment. In this study, we describe the impact of screening HIV-positive adult inpatients with serum cryptococcal antigen (CRAG) at a Tanzanian referral hospital. All adults admitted to the medical ward of Bugando Medical Centre are counseled and tested for HIV. In this prospective cohort study, we consecutively enrolled HIV-positive patients admitted between September 2009 and January 2010. All patients were interviewed, examined and screened with serum CRAG. Patients with positive serum CRAG or signs of meningitis underwent lumbar puncture. Patients were managed according to standard World Health Organization treatment guidelines. Discharge diagnoses and in-hospital mortality were recorded.\ud Of 333 HIV-infected adults enrolled in our study, 15 (4.4%) had confirmed cryptococcal meningitis and 10 of these 15 (66%) died. All patients with cryptococcal meningitis had at least two of four classic symptoms and signs of meningitis: fever, headache, neck stiffness and altered mental status. Cryptococcal meningitis accounted for a quarter of all in-hospital deaths. Despite screening of all HIV-positive adult inpatients with the serum CRAG at the time of admission and prompt treatment with high-dose intravenous fluconazole in those with confirmed cryptococcal meningitis, the in-hospital mortality rate remained unacceptably high. Improved strategies for earlier diagnosis and treatment of HIV, implementation of fluconazole pre-emptive treatment for high-risk patients and acquisition of better resources for treatment of cryptococcal meningitis are needed

FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR)

Adenosylcobalamin, the coenzyme form of vitamin B12, is one Nature's most complex coenzyme whose de novo biogenesis proceeds along either an anaerobic or aerobic metabolic pathway. The aerobic synthesis involves reduction of the centrally chelated cobalt metal ion of the corrin ring from Co(II) to Co(I) before adenosylation can take place. A corrin reductase (CobR) enzyme has been identified as the likely agent to catalyse this reduction of the metal ion. Herein, we reveal how Brucella melitensis CobR binds its coenzyme FAD (flavin dinucleotide) and we also show that the enzyme can bind a corrin substrate consistent with its role in reduction of the cobalt of the corrin ring. Stopped-flow kinetics and EPR reveal a mechanistic asymmetry in CobR dimer that provides a potential link between the two electron reduction by NADH to the single electron reduction of Co(II) to Co(I)

The TIGA technique for detecting gravitational waves with a spherical antenna

We report the results of a theoretical and experimental study of a spherical gravitational wave antenna. We show that it is possible to understand the data from a spherical antenna with 6 radial resonant transducers attached to the surface in the truncated icosahedral arrangement. We find that the errors associated with small deviations from the ideal case are small compared to other sources of error, such as a finite signal-to-noise ratio. An in situ measurement technique is developed along with a general algorithm that describes a procedure for determining the direction of an external force acting on the antenna, including the force from a gravitational wave, using a combination of the transducer responses. The practicality of these techniques was verified on a room-temperature prototype antenna.Comment: 15 pages, 14 figures, submitted to Physical Review

Genetic and Phylogenetic Divergence of Feline Immunodeficiency Virus in the Puma (Puma concolor)

Feline immunodeficiency virus (FIV) is a lentivirus which causes an AIDS-like disease in domestic cats (Felis catus). A number of other felid species, including the puma (Puma concolor), carry a virus closely related to domestic cat FIV. Serological testing revealed the presence of antibodies to FIV in 22% of 434 samples from throughout the geographic range of the puma. FIV-Pco pol gene sequences isolated from pumas revealed extensive sequence diversity, greater than has been documented in the domestic cat. The puma sequences formed two highly divergent groups, analogous to the clades which have been defined for domestic cat and lion (Panthera leo) FIV. The puma clade A was made up of samples from Florida and California, whereas clade B consisted of samples from other parts of North America, Central America, and Brazil. The difference between these two groups was as great as that reported among three lion FIV clades. Within puma clades, sequence variation is large, comparable to between-clade differences seen for domestic cat clades, allowing recognition of 15 phylogenetic lineages (subclades) among puma FIV-Pco. Large sequence divergence among isolates, nearly complete species monophyly, and widespread geographic distribution suggest that FIV-Pco has evolved within the puma species for a long period. The sequence data provided evidence for vertical transmission of FIV-Pco from mothers to their kittens, for coinfection of individuals by two different viral strains, and for cross-species transmission of FIV from a domestic cat to a puma. These factors may all be important for understanding the epidemiology and natural history of FIV in the puma

Discovery of a Gas-Rich Companion to the Extremely Metal-Poor Galaxy DDO 68

We present HI spectral-line imaging of the extremely metal-poor galaxy DDO 68. This system has a nebular oxygen abundance of only 3% Z$_{\odot}$, making it one of the most metal-deficient galaxies known in the local volume. Surprisingly, DDO 68 is a relatively massive and luminous galaxy for its metal content, making it a significant outlier in the mass-metallicity and luminosity-metallicity relationships. The origin of such a low oxygen abundance in DDO 68 presents a challenge for models of the chemical evolution of galaxies. One possible solution to this problem is the infall of pristine neutral gas, potentially initiated during a gravitational interaction. Using archival HI spectral-line imaging obtained with the Karl G. Jansky Very Large Array, we have discovered a previously unknown companion of DDO 68. This low-mass (M$_{\rm HI}$ $=$ 2.8$\times$10$^{7}$ M$_{\odot}$), recently star-forming (SFR$_{\rm FUV}$ $=$ 1.4$\times$10$^{-3}$ M$_{\odot}$ yr$^{-1}$, SFR$_{\rm H\alpha}$ $<$ 7$\times$10$^{-5}$ M$_{\odot}$ yr$^{-1}$) companion has the same systemic velocity as DDO 68 (V$_{\rm sys}$ $=$ 506 km s$^{-1}$; D $=$ 12.74$\pm$0.27 Mpc) and is located at a projected distance of 42 kpc. New HI maps obtained with the 100m Robert C. Byrd Green Bank Telescope provide evidence that DDO 68 and this companion are gravitationally interacting at the present time. Low surface brightness HI gas forms a bridge between these objects.Comment: Accepted for publication in the Astrophysical Journal Letter

Milling plant and soil material in plastic tubes over-estimates carbon and under-estimates nitrogen concentrations

Peer reviewedPostprin

Seasonal forage quality of rangelands across Kansas

The K-State Research and Extension Forage Task Force surveyed Kansas rangelands during the course of seasonal changes to enable producers and managers to better estimate the feed value of their pasture forage during particular times of the year. Kansas’ two distinct rangeland vegetation types, shortgrass and tallgrass prairie, were evaluated. Forage samples were collected monthly from two rangeland sites in each of 10 Kansas counties. Tallgrass vegetation was lowest in acid detergent fiber (ADF) and greatest in crude protein (CP) from May to July, and rapidly increased in ADF and declined in CP the rest of the season. Shortgrass vegetation was also lower in ADF and greater in CP from May to July, but changed less from early summer to the winter than did tallgrass vegetation. Degradable intake protein (DIP) was greatest for tallgrass vegetation in May. Otherwise DIP was similar between tallgrass and shortgrass except in February and March when shortgrass had greater DIP. DIP was greatest in May and June for both vegetation types and gradually declined from June to December. Undegradable intake protein (UIP) values were greater for tallgrass vegetation than for shortgrass vegetation from May through July, but all other months were similar. Seasonal forage quality is different between and within rangeland vegetation types, and identification of dominant vegetation is a key determinant in choosing appropriate animal nutritional management strategies