Some investigations into non passive listening

Our knowledge of the function of the auditory nervous system is based upon a wealth of data obtained, for the most part, in anaesthetised animals. More recently, it has been generally acknowledged that factors such as attention profoundly modulate the activity of sensory systems and this can take place at many levels of processing. Imaging studies, in particular, have revealed the greater activation of auditory areas and areas outside of sensory processing areas when attending to a stimulus. We present here a brief review of the consequences of such non-passive listening and go on to describe some of the experiments we are conducting to investigate them. In imaging studies, using fMRI, we can demonstrate the activation of attention networks that are non-specific to the sensory modality as well as greater and different activation of the areas of the supra-temporal plane that includes primary and secondary auditory areas. The profuse descending connections of the auditory system seem likely to be part of the mechanisms subserving attention to sound. These are generally thought to be largely inactivated by anaesthesia. However, we have been able to demonstrate that even in an anaesthetised preparation, removing the descending control from the cortex leads to quite profound changes in the temporal patterns of activation by sounds in thalamus and inferior colliculus. Some of these effects seem to be specific to the ear of stimulation and affect interaural processing. To bridge these observations we are developing an awake behaving preparation involving freely moving animals in which it will be possible to investigate the effects of consciousness (by contrasting awake and anaesthetized), passive and active listening

Administration of human chorionic gonadotropin at embryo transfer induced ovulation of a first-wave dominant follicle and increased progesterone and transfer pregnancy rates

Beef Cattle Research, 2011 is known as Cattlemen’s Day, 2011Embryo transfer (ET) has become more widespread in recent years as a way to improve cattle genetics. According to the annual statistical survey of the American Embryo Transfer Association, more than 200,000 fresh and frozen bovine embryos were transferred in 2008. But despite advancements in reproductive technologies that have occurred since ET was commercialized in the 1970s, industrywide pregnancy rates are only 62.4 and 56.9% for fresh and frozen-thawed ET, respectively. Using ET helps avoid problems from failed fertilization; however, fertilization failure has been characterized as a relatively unimportant factor of pregnancy loss. Approximately 10% of pregnancy failures resulted from fertilization failure and another 10% from failed embryo development. Approximately 20 to 25% of the pregnancy loss in an ET program could be characterized as early embryonic loss

Modelling eggshell maculation

The eggshells of many avian species are characterised by distinctive patterns of maculation, consisting of speckles, spots, blotches or streaks, the spatial-statistical properties of which vary considerably between (and often within) species. Understanding the mechanisms underlying the production of eggshell maculation would enable us to explore the costs and constraints on the evolution of maculation patterns, but as yet this area is surprisingly understudied. Here I present a simple model of eggshell maculation, which is based on the known biology of pigment deposition, and which can produce a range of realistic maculation patterns. In particular, it provides an explanation for previous observations of maculation heterogeneity and diversity, and allows testable predictions to be made regarding maculation patterns, including a possible signalling role

New directions in island biogeography

Aim: Much of our current understanding of ecological and evolutionary processes comes from island research. With the increasing availability of data on distributions and phylogenetic relationships and new analytical approaches to understanding the processes that shape species distributions and interactions, a re-evaluation of this ever-interesting topic is timely. Location: Islands globally. Methods: We start by arguing that the reasons why island research has achieved so much in the past also apply to the future. We then critically assess the current state of island biogeography, focusing on recent changes in emphasis, including research featured in this special issue of Global Ecology and Biogeography. Finally, we suggest promising themes for the future. We cover both ecological and evolutionary topics, although the greater emphasis on island ecology reflects our own backgrounds and interests. Results: Much ecological theory has been directly or indirectly influenced by research on island biotas. Currently, island biogeography is renascent, with research focusing on, among other things, patterns and processes underlying species interaction networks, species coexistence and the assembly of island communities through ecological and evolutionary time. Continuing island research should provide additional insight into biological invasions and other impacts of human activities, functional diversity and ecosystem functioning, extinction and diversification, species pools and more. Deeper understanding of the similarities and differences between island and mainland systems will aid transferability of island theory to continental regions. Main conclusions: As research in biogeography and related fields expands in new directions, islands continue to provide opportunities for developing insights, both as natural laboratories for ecology and evolution and because of the exceptions islands often present to the usual ‘rules’ of ecology. New data collection initiatives are needed on islands world-wide and should be directed towards filling gaps in our knowledge of within-island distributions of species, as well as the functional traits and phylogenetic relationships of island species

Evaluating investment deferral by incorporating distributed generation in distribution network planning

Environmental concerns, the need to diversify the energy mix, together with technology advances have made Distributed Generation (DG) increase worldwide over recent decades. One of the major and well-recognised benefits of DG is its ability to defer future demand-related investments, providing potentially significant savings and competitive advantage for regulated Distribution Network Operators (DNOs). In this paper an approach that considers the successive elimination method and multistage planning is proposed in order to quantify the investment deferral brought about by DG. Here, each required reinforcement and its implementation schedule affected by the connection of DG can be clearly identified by the DNO. A typical UK distribution network circuit is evaluated. Results show that characteristics of DG such as location, size, power factor and the commissioning time can result in significant reductions of the total planning costs. The investment deferral per MW of connected DG is also investigated as an index that could assist DNOs in evaluating the attractiveness of potential connection points as well as in quantifying the benefit produced by DG

Burnishing tool actuators and their influence on the burnishing force components

The article presents the results of studies on measuring components of force of diamond burnishing of surfaces with variable radius of curvature. The impact of structural elements of burnishing tools of different types on components of burnishing force was analyzed. The impact of different actuators of burnishing tools on components of burnishing force was analyzed. The design of the burnishing tool with an air receiver (bellows with compressed air as an actuator) with a parallelogram-type mounting of the indenter on the four flat posts, which ensures burnishing of profiled and other types of surfaces with constant radial force, was proposed

Subclinical Thyroid Dysfunction and Fracture Risk: A Meta-analysis

IMPORTANCE Associations between subclinical thyroid dysfunction and fractures are unclear and clinical trials are lacking. OBJECTIVE To assess the association of subclinical thyroid dysfunction with hip, nonspine, spine, or any fractures. DATA SOURCES AND STUDY SELECTION The databases of MEDLINE and EMBASE (inception to March 26, 2015) were searched without language restrictions for prospective cohort studies with thyroid function data and subsequent fractures. DATA EXTRACTION Individual participant data were obtained from 13 prospective cohorts in the United States, Europe, Australia, and Japan. Levels of thyroid function were defined as euthyroidism (thyroid-stimulating hormone [TSH], 0.45-4.49 mIU/L), subclinical hyperthyroidism (TSH <0.45 mIU/L), and subclinical hypothyroidism (TSH ≥4.50-19.99 mIU/L) with normal thyroxine concentrations. MAIN OUTCOME AND MEASURES The primary outcome was hip fracture. Any fractures, nonspine fractures, and clinical spine fractures were secondary outcomes. RESULTS Among 70,298 participants, 4092 (5.8%) had subclinical hypothyroidism and 2219 (3.2%) had subclinical hyperthyroidism. During 762,401 person-years of follow-up, hip fracture occurred in 2975 participants (4.6%; 12 studies), any fracture in 2528 participants (9.0%; 8 studies), nonspine fracture in 2018 participants (8.4%; 8 studies), and spine fracture in 296 participants (1.3%; 6 studies). In age- and sex-adjusted analyses, the hazard ratio (HR) for subclinical hyperthyroidism vs euthyroidism was 1.36 for hip fracture (95% CI, 1.13-1.64; 146 events in 2082 participants vs 2534 in 56,471); for any fracture, HR was 1.28 (95% CI, 1.06-1.53; 121 events in 888 participants vs 2203 in 25,901); for nonspine fracture, HR was 1.16 (95% CI, 0.95-1.41; 107 events in 946 participants vs 1745 in 21,722); and for spine fracture, HR was 1.51 (95% CI, 0.93-2.45; 17 events in 732 participants vs 255 in 20,328). Lower TSH was associated with higher fracture rates: for TSH of less than 0.10 mIU/L, HR was 1.61 for hip fracture (95% CI, 1.21-2.15; 47 events in 510 participants); for any fracture, HR was 1.98 (95% CI, 1.41-2.78; 44 events in 212 participants); for nonspine fracture, HR was 1.61 (95% CI, 0.96-2.71; 32 events in 185 participants); and for spine fracture, HR was 3.57 (95% CI, 1.88-6.78; 8 events in 162 participants). Risks were similar after adjustment for other fracture risk factors. Endogenous subclinical hyperthyroidism (excluding thyroid medication users) was associated with HRs of 1.52 (95% CI, 1.19-1.93) for hip fracture, 1.42 (95% CI, 1.16-1.74) for any fracture, and 1.74 (95% CI, 1.01-2.99) for spine fracture. No association was found between subclinical hypothyroidism and fracture risk. CONCLUSIONS AND RELEVANCE Subclinical hyperthyroidism was associated with an increased risk of hip and other fractures, particularly among those with TSH levels of less than 0.10 mIU/L and those with endogenous subclinical hyperthyroidism. Further study is needed to determine whether treating subclinical hyperthyroidism can prevent fractures

Recycling sediments between source and sink during a eustatic cycle: Systems of late Quaternary northwestern Gulf of Mexico Basin

The northwestern Gulf of Mexico Basin is an ideal natural laboratory to study and understand source-to-sink systems. An extensive grid of high-resolution seismic data, hundreds of sediment cores and borings and a robust chronostratigraphic framework were used to examine the evolution of late Quaternary depositional systems of the northwestern Gulf of Mexico throughout the last eustatic cycle (~125 ka to Present). The study area includes fluvial systems with a wide range of drainage basin sizes, climate settings and water and sediment discharges. Detailed paleogeographic reconstructions are used to derive volumetric estimates of sediment fluxes (Volume Accumulation Rates). The results show that the response of rivers to sea-level rise and fall varied across the region. Larger rivers, including the former Mississippi, Western Louisiana (presumably the ancestral Red River), Brazos, Colorado and Rio Grande rivers, constructed deltas that advanced across the shelf in step-wise fashion during Marine Isotope Stages (MIS) 5-2. Sediment delivery to these deltas increased during the overall sea-level fall due to increases in drainage basin area and erosion of sediment on the inner shelf, where subsidence is minimal, and transport of that sediment to the more rapidly subsiding outer shelf. The sediment supply from the Brazos River to its delta increased at least 3-fold and the supply of the Colorado River increased at least 6-fold by the late stages of sea-level fall through the lowstand. Repeated filling and purging of fluvial valleys from ~119-22 ka contributed to the episodic growth of falling-stage deltas.During the MIS 2 lowstand (~22-17 ka), the Mississippi River abandoned its falling-stage fluvial-deltaic complex on the western Louisiana shelf and drained to the Mississippi Canyon. Likewise, the Western Louisiana delta was abandoned, presumably due to merger of the Red River with the Mississippi River, terminating growth of the Western Louisiana delta. The Brazos River abandoned its MIS 3 shelf margin delta to merge with the Trinity, Sabine and Calcasieu rivers and together these rivers nourished a lowstand delta and slope fan complex. The Colorado and Rio Grande rivers behaved more as point sources of sediment to thick lowstand delta-fan complexes.Lowstand incised valleys exhibit variable morphologies that mainly reflect differences in onshore and offshore relief and the time intervals these valleys were occupied. They are deeper and wider than falling stage channel belts and are associated with a shelf-wide surface of erosion (sequence boundary).During the early MIS 1 (~17 ka to 7~10 ka) sea-level rise, the offshore incised valleys of the Calcasieu, Sabine, Trinity, Brazos, Colorado, and Rio Grande rivers were filled with sediment. The offshore valleys of smaller rivers of central Texas would not be filled until the late Holocene, mainly by highstand mud. The lower, onshore portions of east Texas incised valleys were filled with sediment mainly during the Holocene, with rates of aggradation in the larger Brazos and Colorado valleys being in step with sea-level rise. Smaller rivers filled their valleys with back-stepping fluvial, estuarine and tidal delta deposits that were offset by flooding surfaces. In general, the sediment trapping capacity of bays increased as evolving barrier islands and peninsulas slowly restricted tidal exchange with the Gulf and valley filling led to more shallow, wider bays. A widespread period of increased riverine sediment flux and delta growth is attributed to climate change during MIS 1, between ~11.5 and 8.0 ka, and occurred mainly under cool-wet climate conditions.Relatively small sea-level oscillations during the MIS 1 transgression (~17 ka to ~4.0 ka) profoundly influenced coastal evolution, as manifested by landward stepping shorelines, on the order of tens of kilometers within a few thousand years. The current barriers, strand plains and chenier plains of the study area formed at different times over the past ~8 ka, due mainly to differences in sand supply and the highly variable relief on the MIS 2 surface on which these systems formed.Modern highstand deposition on the continental shelf formed the Texas Mud Blanket, which occurs on the central Texas shelf and records a remarkable increase in fine-grained sediment supply. This increase is attributed to greater delivery of sediments from the Colorado and Brazos rivers, which had filled their lower valleys and abandoned their transgressive deltas by late Holocene time, and to an increase in westward directed winds and surface currents that delivered suspended sediments from the Mississippi River to the Texas shelf.Collectively, our results demonstrate that source-to-sink analyses in low gradient basin settings requires a long-term perspective, ideally a complete eustatic cycle, because most of the sediment that was delivered to the basin by rivers underwent more than one cycle of erosion, transport and sedimentation that was regulated by sea-level rise and fall. Climate was a secondary control. The export of sediments from the hinterland to the continental shelf was not directly in step with temperature change, but rather varied between different fluvial-deltaic systems

Scattering of charge carriers in graphene induced by topological defects

We study the scattering of graphene quasiparticles by topological defects, represented by holes, pentagons and heptagons. For holes, we found that at low concentration they give a negligible contribution to the resistivity. Whenever pentagons or heptagons are introduced we realize that a fermionic current is scattered by defects

Stomatal and Non-Stomatal Leaf Responses during Two Sequential Water Stress Cycles in Young Coffea canephora Plants

This research was funded by Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ, Brazil) granted to E.C. (200.957/2022), together with fellowships awarded to D.F.B., W.P.B. and L.Z.C. (E-26/200.327/2020, E-26/200.172/2021, and E-26/203.158/2023). The research was additionally funded by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Brazil) with fellowships granted to G.A.R.S., C.M.A., A.R.S., L.C.S.B. and L.F.T.B. (88887.968322/2024-00, 88887.903335/2023-00, 88887.671147/2022-00, 88887.704841/2022-00, and 88887.822657/2023-00), by Fundação de Amparo à Pesquisa e Inovação do Espírito Santo (FAPES, Brazil) by fellowship awarded to M.R. (2022–M465D), and National Council for Scientific and Technological Development (CNPq, Brazil) by fellowship awarded to E.C (304470/2023-6). © 2024 by the authors. Licensee MDPI, Basel, Switzerland.Understanding the dynamics of physiological changes involved in the acclimation responses of plants after their exposure to repeated cycles of water stress is crucial to selecting resilient genotypes for regions with recurrent drought episodes. Under such background, we tried to respond to questions as: (1) Are there differences in the stomatal-related and non-stomatal responses during water stress cycles in different clones of Coffea canephora Pierre ex A. Froehner? (2) Do these C. canephora clones show a different response in each of the two sequential water stress events? (3) Is one previous drought stress event sufficient to induce a kind of “memory” in C. canephora? Seven-month-old plants of two clones (’3V’ and ‘A1’, previously characterized as deeper and lesser deep root growth, respectively) were maintained well-watered (WW) or fully withholding the irrigation, inducing soil water stress (WS) until the soil matric water potential (Ψmsoil) reached ≅ −0.5 MPa (−500 kPa) at a soil depth of 500 mm. Two sequential drought events (drought-1 and drought-2) attained this Ψmsoil after 19 days and were followed by soil rewatering until a complete recovery of leaf net CO2 assimilation rate (Anet) during the recovery-1 and recovery-2 events. The leaf gas exchange, chlorophyll a fluorescence, and leaf reflectance parameters were measured in six-day frequency, while the leaf anatomy was examined only at the end of the second drought cycle. In both drought events, the WS plants showed reduction in stomatal conductance and leaf transpiration. The reduction in internal CO2 diffusion was observed in the second drought cycle, expressed by increased thickness of spongy parenchyma in both clones. Those stomatal and anatomical traits impacted decreasing the Anet in both drought events. The ‘3V’ was less influenced by water stress than the ‘A1’ genotype in Anet, effective quantum yield in PSII photochemistry, photochemical quenching, linear electron transport rate, and photochemical reflectance index during the drought-1, but during the drought-2 event such an advantage disappeared. Such physiological genotype differences were supported by the medium xylem vessel area diminished only in ‘3V’ under WS. In both drought cycles, the recovery of all observed stomatal and non-stomatal responses was usually complete after 12 days of rewatering. The absence of photochemical impacts, namely in the maximum quantum yield of primary photochemical reactions, photosynthetic performance index, and density of reaction centers capable of QA reduction during the drought-2 event, might result from an acclimation response of the clones to WS. In the second drought cycle, the plants showed some improved responses to stress, suggesting “memory” effects as drought acclimation at a recurrent drought.publishersversionpublishe